ATE429416T1 - Cyanophenoxy-carbonsäuren und zusammensetzungen für die freisetzung aktiver substanzen - Google Patents

Cyanophenoxy-carbonsäuren und zusammensetzungen für die freisetzung aktiver substanzen

Info

Publication number
ATE429416T1
ATE429416T1 AT01979883T AT01979883T ATE429416T1 AT E429416 T1 ATE429416 T1 AT E429416T1 AT 01979883 T AT01979883 T AT 01979883T AT 01979883 T AT01979883 T AT 01979883T AT E429416 T1 ATE429416 T1 AT E429416T1
Authority
AT
Austria
Prior art keywords
compositions
cyanophenoxy
release
active substances
carbonic acids
Prior art date
Application number
AT01979883T
Other languages
English (en)
Inventor
Destardi Moye-Sherman
David Gschneidner
Original Assignee
Emisphere Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emisphere Tech Inc filed Critical Emisphere Tech Inc
Application granted granted Critical
Publication of ATE429416T1 publication Critical patent/ATE429416T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT01979883T 2000-09-06 2001-09-05 Cyanophenoxy-carbonsäuren und zusammensetzungen für die freisetzung aktiver substanzen ATE429416T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23033100P 2000-09-06 2000-09-06
US23723500P 2000-10-02 2000-10-02
PCT/US2001/041984 WO2002020466A1 (en) 2000-09-06 2001-09-05 Cyanophenoxy carboxylic acid compounds and compositions for delivering active agents

Publications (1)

Publication Number Publication Date
ATE429416T1 true ATE429416T1 (de) 2009-05-15

Family

ID=26924131

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01979883T ATE429416T1 (de) 2000-09-06 2001-09-05 Cyanophenoxy-carbonsäuren und zusammensetzungen für die freisetzung aktiver substanzen

Country Status (14)

Country Link
US (2) US7115663B2 (de)
EP (1) EP1317419B1 (de)
JP (1) JP5089845B2 (de)
CN (1) CN1313441C (de)
AT (1) ATE429416T1 (de)
AU (1) AU2002211805A1 (de)
BR (1) BR0114799A (de)
CA (1) CA2421575C (de)
DE (1) DE60138468D1 (de)
DK (1) DK1317419T3 (de)
ES (1) ES2321693T3 (de)
NZ (1) NZ524138A (de)
PT (1) PT1317419E (de)
WO (1) WO2002020466A1 (de)

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WO2001051454A1 (en) 2000-01-13 2001-07-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
AU2002352974A1 (en) 2001-11-29 2003-06-10 Emisphere Technologies, Inc. Formulations for oral administration of cromolyn sodium
US20030198666A1 (en) * 2002-01-07 2003-10-23 Richat Abbas Oral insulin therapy
AU2004204727B8 (en) * 2003-01-06 2006-11-09 Emisphere Technologies, Inc. Night-time oral insulin therapy
US20050203001A1 (en) * 2004-03-05 2005-09-15 Emisphere Technologies, Inc. Oral insulin therapies and protocol
AU2005214167B2 (en) * 2004-02-13 2008-08-07 Warner-Lambert Company Llc Androgen receptor modulators
JP2007536268A (ja) 2004-05-06 2007-12-13 エミスフェアー・テクノロジーズ・インク 固体剤形の湿性ヘパリン
CA2565188C (en) * 2004-05-14 2014-03-04 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
WO2005117854A2 (en) 2004-05-14 2005-12-15 Emisphere Technologies, Inc. Aryl ketone compounds and compositions for delivering active agents
RU2406504C2 (ru) * 2004-05-19 2010-12-20 Эмисфире Текнолоджис, Инк. Способы изготовления лекарственных составов ацикловира
US9498487B2 (en) 2004-05-19 2016-11-22 Emisphere Technologies, Inc. Topical cromolyn formulations
BRPI0513020A (pt) * 2004-07-08 2008-04-22 Warner Lambert Co moduladores de andrÈgenio, seus usos, composição farmacêutica, formulação farmacêutica tópica e artigo de fabricação
JP2008509145A (ja) 2004-08-03 2008-03-27 エミスフィアー テクノロジーズ インコーポレイテッド 抗糖尿病性経口インスリン−ビグアニドの組み合わせ
US20060078623A1 (en) * 2004-08-13 2006-04-13 Emisphere Technologies, Inc. Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent
JP4907552B2 (ja) 2004-12-29 2012-03-28 エミスフェアー・テクノロジーズ・インク ガリウム塩の製剤
WO2006076692A1 (en) 2005-01-12 2006-07-20 Emisphere Technologies, Inc. Compositions for buccal delivery of parathyroid hormone
TW200724139A (en) * 2005-05-05 2007-07-01 Warner Lambert Co Androgen modulators
US8975227B2 (en) 2005-07-15 2015-03-10 Emisphere Technologies, Inc. Intraoral dosage forms of glucagon
US20090170886A1 (en) * 2005-08-08 2009-07-02 Pfizer Inc Androgen modulators
US8927015B2 (en) 2006-04-12 2015-01-06 Emisphere Technologies, Inc. Formulations for delivering insulin
WO2007133944A2 (en) 2006-05-09 2007-11-22 Emisphere Technologies, Inc. Topical administration of acyclovir
JP5475443B2 (ja) 2006-06-28 2014-04-16 エミスフェアー・テクノロジーズ・インク 硝酸ガリウム製剤
WO2008022242A2 (en) * 2006-08-18 2008-02-21 Emisphere Technologies, Inc. Synthesis of propyl phenoxy ethers and use as delivery agents
EP2057112B1 (de) 2006-08-31 2018-12-19 Emisphere Technologies, Inc. Verbindungen und zusammensetzungen zur wirkstofffreisetzung
EP2114145B1 (de) * 2007-02-08 2017-11-01 Emisphere Technologies, Inc. Mittel zur förderung von phenylalkylcarboxylsäure
CA3013149C (en) 2007-03-13 2021-12-07 Jds Therapeutics, Llc Methods and compositions for the sustained release of chromium
WO2009002867A2 (en) 2007-06-26 2008-12-31 Nutrition 21, Inc. Multiple unit dosage form having a therapeutic agents in combination with a nutritional supplement
US20110039930A1 (en) 2009-08-03 2011-02-17 Emisphere Technologies, Inc. Fast-acting naproxen composition with reduced gastrointestinal effects
MX344925B (es) 2011-03-01 2017-01-11 N21 Acquisition Holding Llc Composiciones de insulina y cromo para el tratamiento y prevención de diabetes, hipoglucemia y alteraciones relacionadas.
EP2897620B1 (de) 2012-09-21 2020-07-22 Intensity Therapeutics, Inc Verfahren zur behandlung von karzinomen
EP2919804B1 (de) 2012-11-13 2018-01-31 Adocia Schnell wirkende insulinformulierung mit einer anionischen substituierten verbindung
FR3020947B1 (fr) * 2014-05-14 2018-08-31 Adocia Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations
US9795678B2 (en) 2014-05-14 2017-10-24 Adocia Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound
FR3043557B1 (fr) 2015-11-16 2019-05-31 Adocia Composition a action rapide d'insuline comprenant un citrate substitue
MX2018009748A (es) 2016-02-11 2019-02-07 Nutrition 21 Llc Composiciones que contienen cromo para mejorar la salud y el estado físico.
WO2021183752A1 (en) 2020-03-12 2021-09-16 Baxter International Inc. Daptomycin formulations containing a combination of sorbitol and mannitol

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US4060619A (en) * 1976-01-14 1977-11-29 Ayerst Mckenna And Harrison Ltd. 1,4-Dihydro-4-oxo-benzothiopyrano (4,3-b)pyridine-2-carboxylates and derivatives
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US5443841A (en) 1992-06-15 1995-08-22 Emisphere Technologies, Inc. Proteinoid microspheres and methods for preparation and use thereof
EP0513675B1 (de) * 1991-05-13 1996-09-11 Fujisawa Pharmaceutical Co., Ltd. Neue Peptid-Verbindungen und Verfahren zur Herstellung davon
US5401516A (en) 1992-12-21 1995-03-28 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
IL108432A (en) * 1993-01-29 1997-09-30 Sankyo Co DERIVATIVES OF 3, 5-DIHYDROXY-7- £1, 2, 6, 7, 8, 8a-HEXAHYDRO-2- METHYL-8- (SUBSTITUTED ALKANOYLOXY)-1-NAPHTHYL| HEPTANOIC ACID AND THEIR LACTONES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
JPH06279389A (ja) * 1993-03-30 1994-10-04 Terumo Corp アミジノフェニルエーテル誘導体
US5643957A (en) 1993-04-22 1997-07-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
CA2160693C (en) 1993-04-22 2010-03-16 Sam J. Milstein Oral drug delivery compositions and methods
US5866536A (en) 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5776888A (en) 1997-02-07 1998-07-07 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6289286B1 (en) 1998-05-29 2001-09-11 Biacore Ab Surface regeneration of biosensors and characterization of biomolecules associated therewith
EP1146860A4 (de) 1999-01-08 2002-07-03 Emisphere Tech Inc Polymere arzneimittelabgabesysteme und -verbindungen
IL149337A0 (en) 1999-11-05 2002-11-10 Emisphere Tech Inc Phenoxy carboxylic acid compounds and compositions for delivering active agents

Also Published As

Publication number Publication date
EP1317419B1 (de) 2009-04-22
BR0114799A (pt) 2003-12-30
US7115663B2 (en) 2006-10-03
AU2002211805A1 (en) 2002-03-22
US7390834B2 (en) 2008-06-24
EP1317419A4 (de) 2005-09-28
US20030199427A1 (en) 2003-10-23
CN1313441C (zh) 2007-05-02
EP1317419A1 (de) 2003-06-11
DE60138468D1 (de) 2009-06-04
JP2004521862A (ja) 2004-07-22
NZ524138A (en) 2004-12-24
DK1317419T3 (da) 2009-06-15
JP5089845B2 (ja) 2012-12-05
CN1454205A (zh) 2003-11-05
PT1317419E (pt) 2009-05-08
ES2321693T3 (es) 2009-06-10
CA2421575A1 (en) 2002-03-14
CA2421575C (en) 2011-07-12
US20060264356A1 (en) 2006-11-23
WO2002020466A1 (en) 2002-03-14
WO2002020466B1 (en) 2002-07-25

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