WO1999042087A3 - Controlled release potassium chloride pellet based pharmaceutical compositions having a high active ingredient content - Google Patents
Controlled release potassium chloride pellet based pharmaceutical compositions having a high active ingredient content Download PDFInfo
- Publication number
- WO1999042087A3 WO1999042087A3 PCT/HU1999/000013 HU9900013W WO9942087A3 WO 1999042087 A3 WO1999042087 A3 WO 1999042087A3 HU 9900013 W HU9900013 W HU 9900013W WO 9942087 A3 WO9942087 A3 WO 9942087A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- potassium chloride
- weight
- controlled release
- pellets
- active ingredient
- Prior art date
Links
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 title abstract 10
- 239000001103 potassium chloride Substances 0.000 title abstract 5
- 235000011164 potassium chloride Nutrition 0.000 title abstract 5
- 239000008188 pellet Substances 0.000 title abstract 4
- 238000013270 controlled release Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 239000001828 Gelatine Substances 0.000 abstract 2
- 239000002775 capsule Substances 0.000 abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 2
- 229920000159 gelatin Polymers 0.000 abstract 2
- 235000019322 gelatine Nutrition 0.000 abstract 2
- JIGUQPWFLRLWPJ-UHFFFAOYSA-N Ethyl acrylate Chemical compound CCOC(=O)C=C JIGUQPWFLRLWPJ-UHFFFAOYSA-N 0.000 abstract 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 1
- 239000012752 auxiliary agent Substances 0.000 abstract 1
- 239000011247 coating layer Substances 0.000 abstract 1
- 239000010410 layer Substances 0.000 abstract 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 1
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 1
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000000454 talc Substances 0.000 abstract 1
- 229910052623 talc Inorganic materials 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Medicinal Preparation (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SK1188-2000A SK287281B6 (en) | 1998-02-20 | 1999-02-19 | Controlled release multi-dosage pharmaceutical composition in solid peroral form and method for the preparation thereof |
AU25404/99A AU2540499A (en) | 1998-02-20 | 1999-02-19 | Controlled release potassium chloride pellet based pharmaceutical compositions having a high active ingredient content |
PL343268A PL193028B1 (en) | 1998-02-20 | 1999-02-19 | Controlled release potassium chloride pellet based pharmaceutical compositions having a high active ingredient content |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HUP9800369 | 1998-02-20 | ||
HU9800369A HU221435B (en) | 1998-02-20 | 1998-02-20 | Pellet-based pharmaceutical composition of controlled release with high content of potassium-chloride, and process for it's production |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999042087A2 WO1999042087A2 (en) | 1999-08-26 |
WO1999042087A3 true WO1999042087A3 (en) | 1999-11-25 |
Family
ID=89996172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/HU1999/000013 WO1999042087A2 (en) | 1998-02-20 | 1999-02-19 | Controlled release potassium chloride pellet based pharmaceutical compositions having a high active ingredient content |
Country Status (6)
Country | Link |
---|---|
AU (1) | AU2540499A (en) |
CZ (1) | CZ299182B6 (en) |
HU (1) | HU221435B (en) |
PL (1) | PL193028B1 (en) |
SK (1) | SK287281B6 (en) |
WO (1) | WO1999042087A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19928312A1 (en) * | 1999-06-16 | 2000-12-21 | Schering Ag | Drug preparation with delayed drug delivery |
DE10347242A1 (en) | 2003-10-10 | 2005-05-04 | Wella Ag | Dye-containing pellets for dyeing keratin fibers |
EA014262B1 (en) * | 2006-05-19 | 2010-10-29 | Эгиш Дьёдьсердьяр Ньильваношан Мюкёдё Ресвеньтаршашаг | Process for the preparation of a pallet mass |
DE102008063800A1 (en) | 2008-12-19 | 2010-06-24 | Henkel Ag & Co. Kgaa | Coated colorants |
CN102961363B (en) * | 2012-12-14 | 2014-09-17 | 河南中帅医药科技股份有限公司 | Potassium chloride slow release capsule |
EP3213747B1 (en) | 2016-03-04 | 2019-02-13 | Laboratorio Reig Jofre S.A. | Tablets with a high-content of active ingredients useful for treating hair loss or stimulating its growth |
EP4308286A1 (en) | 2021-03-16 | 2024-01-24 | Symrise AG | Active substance capsules |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2087235A (en) * | 1980-11-12 | 1982-05-26 | Ciba Geigy Ag | A granular delayed-release form of pharmaceutical active substances |
WO1984002843A1 (en) * | 1983-01-26 | 1984-08-02 | Egyt Gyogyszervegyeszeti Gyar | Process for the preparation of sustained release pharmaceutical compositions having a high active ingredient content |
GB2157170A (en) * | 1984-03-23 | 1985-10-23 | Ciba Geigy Ag | Quick-disintegrating pressed shapes |
US5397574A (en) * | 1993-10-04 | 1995-03-14 | Andrx Pharmaceuticals, Inc. | Controlled release potassium dosage form |
-
1998
- 1998-02-20 HU HU9800369A patent/HU221435B/en unknown
-
1999
- 1999-02-19 WO PCT/HU1999/000013 patent/WO1999042087A2/en active IP Right Grant
- 1999-02-19 SK SK1188-2000A patent/SK287281B6/en not_active IP Right Cessation
- 1999-02-19 AU AU25404/99A patent/AU2540499A/en not_active Abandoned
- 1999-02-19 PL PL343268A patent/PL193028B1/en unknown
- 1999-02-19 CZ CZ20002858A patent/CZ299182B6/en not_active IP Right Cessation
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2087235A (en) * | 1980-11-12 | 1982-05-26 | Ciba Geigy Ag | A granular delayed-release form of pharmaceutical active substances |
WO1984002843A1 (en) * | 1983-01-26 | 1984-08-02 | Egyt Gyogyszervegyeszeti Gyar | Process for the preparation of sustained release pharmaceutical compositions having a high active ingredient content |
GB2157170A (en) * | 1984-03-23 | 1985-10-23 | Ciba Geigy Ag | Quick-disintegrating pressed shapes |
US5397574A (en) * | 1993-10-04 | 1995-03-14 | Andrx Pharmaceuticals, Inc. | Controlled release potassium dosage form |
Non-Patent Citations (1)
Title |
---|
THOMA, K. ET AL: "Preparation and testing of potassium chloride diffusion pellets", PHARM. IND. (1989), 51(6), 685-9, XP002116009 * |
Also Published As
Publication number | Publication date |
---|---|
HUP9800369A1 (en) | 2000-08-28 |
AU2540499A (en) | 1999-09-06 |
SK11882000A3 (en) | 2001-01-18 |
PL193028B1 (en) | 2007-01-31 |
CZ20002858A3 (en) | 2001-01-17 |
SK287281B6 (en) | 2010-05-07 |
WO1999042087A2 (en) | 1999-08-26 |
HU221435B (en) | 2002-10-28 |
CZ299182B6 (en) | 2008-05-14 |
HU9800369D0 (en) | 1998-04-28 |
PL343268A1 (en) | 2001-08-13 |
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