EP4308286A1 - Active substance capsules - Google Patents

Active substance capsules

Info

Publication number
EP4308286A1
EP4308286A1 EP21712800.8A EP21712800A EP4308286A1 EP 4308286 A1 EP4308286 A1 EP 4308286A1 EP 21712800 A EP21712800 A EP 21712800A EP 4308286 A1 EP4308286 A1 EP 4308286A1
Authority
EP
European Patent Office
Prior art keywords
sodium
peg
acid
potassium
sulfate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21712800.8A
Other languages
German (de)
French (fr)
Inventor
Ralf Bertram
Marcus HÖFLICH
Marek Münstermann
Benjamin ROST
Andreas Vogel
Britta RAABE
Christina KOEPKE
Lisette HOFFARTH
Daniela GREGOR
Nadine KRUG
Ines SCHÜNEMANN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Symrise AG
Original Assignee
Symrise AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symrise AG filed Critical Symrise AG
Publication of EP4308286A1 publication Critical patent/EP4308286A1/en
Pending legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B01J13/046—Making microcapsules or microballoons by physical processes, e.g. drying, spraying combined with gelification or coagulation
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/02—Acyclic compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/04—Oxygen or sulfur attached to an aliphatic side-chain of a carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/14—Polymerisation; cross-linking
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0097—Dye preparations of special physical nature; Tablets, films, extrusion, microcapsules, sheets, pads, bags with dyes
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/0039—Coated compositions or coated components in the compositions, (micro)capsules
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D9/00—Compositions of detergents based essentially on soap
    • C11D9/005—Synthetic soaps
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D9/00—Compositions of detergents based essentially on soap
    • C11D9/04—Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
    • C11D9/44—Perfumes; Colouring materials; Brightening agents ; Bleaching agents
    • C11D9/444—Dyes; Pigments

Definitions

  • the present invention is in the field of detergent preparations and relates to active ingredient capsules with stably incorporated dyes.
  • Core-shell capsules containing microcrystalline cellulose in the core are well known from the prior art, namely, for example
  • WO 2017 107628 A1 also discloses chitosan capsules which contain microcrystalline cellulose in the capsule shell.
  • the object of the present invention was therefore to provide capsules loaded with active ingredients and dyes, in which the active ingredients and dyes are stably incorporated, so that no bleeding takes place.
  • the capsules should be resistant to breakage, so that a sufficiently large or prolonged mechanical force is required before they break open and release both the dye and the active ingredient.
  • the capsules should be surfactant-stable, i.e. the shell should not disintegrate even in an environment containing a high level of surfactants, such as a soap base or a cream.
  • a first object of the invention relates to active ingredient capsules that can be obtained or obtained by
  • Another subject of the invention relates to an analogous production process, comprising or consisting of the following steps:
  • microcrystalline fibers specifically microcrystalline cellulose
  • the fiber is sealed with the dye in the second step.
  • the capsules are produced by coacervation in a hardening or precipitation bath and are not only extremely break-resistant, but also surfactant-stable.
  • the active substance capsules according to the invention can be obtained as described above by providing an emulsion comprising fibers, active substances, dyes and gel formers and dripping the emulsion into a hardening or precipitation bath.
  • the capsules are intensely colored after production. However, since they are only added to the end products in small amounts, they only affect their color when they are mechanically broken up and then primarily color the foam.
  • microcrystalline is understood to mean fibers or fiber fragments that have dimensions of about 100 to about 1,500 ⁇ m, preferably from about 200 to about 1,200 ⁇ m and in particular in their longest extent (“length”) from about 500 to about 1000 ⁇ m.
  • these fibers are spherical in shape.
  • MCC microcrystalline cellulose
  • MKZ microcrystalline cellulose
  • E460i microcrystalline cellulose
  • Microcrystalline cellulose is used in particular in direct tabletting. MCC is made from woody parts of plants, not from waste paper. Here, the vegetable cellulose is freed from non-crystalline cellulose parts with diluted hydrochloric acid at temperatures above 100 °C. Thereafter, optional carboxylation can occur to increase hydrophilicity. Thus, a microcrystalline carboxy- or carboxymethyl cellulose is also included in the present invention.
  • component (b) the selection of the active ingredients that form component (b) is not critical since it depends only on the intended use. However, perfumes and/or antimicrobial agents are particularly preferred.
  • Perfumes which may be mentioned are mixtures of natural and synthetic fragrances. Natural fragrances are extracts of flowers (lily, lavender, rose, jasmine, neroli, ylang-ylang), stems and leaves (geranium, patchouli, petitgrain), fruits (aniseed, coriander, caraway, juniper), fruit peel (bergamot, lemon, oranges), roots (mace, angelica, celery, cardamom, costus, iris, Calmus), wood (pine, sand egg, guaiac, cedar, rosewood), herbs and grasses (tarragon, lemongrass, sage, thyme).
  • Typical synthetic fragrance compounds are products of the ester, ether, aldehyde, ketone, alcohol and hydrocarbon type.
  • Perfume compounds of the ester type are, for example, benzyl acetate, phenoxyethyl isobutyrate, p-tert-butylcyclohexyl acetate, linalyl acetate, dimethylbenzylcarbinyl acetate, phenylethyl acetate, linalyl benzoate, benzyl formate, ethylmethylphenylglycinate, allylcyclohexylpropionate, styrallylpropionate and benzyl salicylate.
  • the ethers include, for example, benzyl ethyl ether
  • the aldehydes include, for example, the linear alkanals with 8 to 18 carbon atoms, citral, citronellal, citronellyloxyacetaldehyde, cyclamenaldehyde, hydroxycitronellal, lilial and bourgeonal
  • the ketones include, for example, the ionones, a-isomethylionone and methylcedryl ketone
  • the alcohols anethole, citronellol, eugenol, isoeugenol, geraniol, linalool, phenylethyl alcohol and terpineol
  • the hydrocarbons mainly include terpenes and balms.
  • fragrance oils of lower volatility which are mostly used as aroma components, are also suitable as perfume oils, for example sage oil, camomile oil, clove oil, lemon balm oil, mint oil, cinnamon leaf oil, lime blossom oil, juniper berry oil, vetiver oil, olibanum oil, galbanum oil, labolanum oil and lavandin oil.
  • flavors examples include peppermint oil, spearmint oil, anise oil, star anise oil, caraway oil, eucalyptus oil, fennel oil, lemon oil, wintergreen oil, clove oil, menthol and the like.
  • Suitable antimicrobial agents can be selected from the group consisting of benzoic acid and para-hydroxybenzoic acid, their esters and salts, benzyl benzoate, propionic acid and their salts, salicylic acid and their salts, 2,4-hexadienoic acid (sorbic acid) and their Salts, levulinic acid and its salts, anisic acid and its salts, perillaic acid and its salts, cinnamic acid and its salts, formaldehyde and paraformaldehyde, 4-hydroxybenzaldehyde, ortho-, meta- and para-anisaldehyde, cinnamaldehyde, cinnamic alcohol, 2-hydroxybiphenyl ether and Its salts, 2-zinc sulfidopyridine N-oxide, inorganic sulfites and bisulfites, sodium iodate, chlorobutanol, 4-ethylmercury(II)-5-amino
  • Phenylpropanol, o-cymen-5-ol, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, 4-hydroxyacetophenone and mixtures thereof are particularly preferred.
  • Pigments are preferably used as dyes, the particle diameter of which is smaller by a factor of 10 to 100 and in particular by a factor of 20 to 50 than the length of the microcrystalline fibers.
  • Preferred gel formers within the scope of the invention are substances which can form gels in aqueous solution at temperatures above 40.degree.
  • Typical examples of such gel formers are heteropolysaccharides and proteins.
  • Preferred thermogelling heteropolysaccharides are agaroses, which can also be present in the form of the agar-agar obtainable from red algae together with up to 30% by weight of non-gel-forming agaropectins.
  • the main components of agaroses are linear polysaccharides made from galactose and 3,6-anhydro-L-galactose with alternating 1,3- and 1,4-glycosidic bonds.
  • the heteropolysaccharides preferably have a molecular weight of 110,000 to 160,000 and are both odorless and tasteless. Suitable alternatives are pectins, xanthans (including xanthan gum) and mixtures thereof. Other preferred types are those that still form gels in a 1% by weight aqueous solution, which below 80° C. do not melt and solidify again above 40°C. Examples from the group of thermo-gelling proteins are the various gelatins.
  • alginic acid or its salts are preferably used as the gelling agent.
  • Alginic acid is a mixture of carboxyl-containing polysaccharides with the following idealized monomer unit:
  • alginic acid or alginates The average molecular weight of alginic acid or alginates is in the range from 150,000 to 250,000.
  • Salts of alginic acid and its complete and partial neutralization products are understood to mean, in particular, the alkali metal salts, preferably sodium alginate ("algin"), and the ammonium and alkaline earth metal salts.
  • Mixed alginates for example sodium/magnesium or sodium/calcium alginates, are particularly preferred.
  • carboxymethyl cellulose and anionic chitosan derivatives for example the carboxylation and especially succinylation products, are also suitable for this.
  • chitosans can also be used as gel formers.
  • biopolymers that also belong to the group of hydrocolloids. From a chemical point of view, these are partially deacetylated chitins with different molecular weights, which contain the following - idealized - monomer unit:
  • chitosans In contrast to most hydrocolloids, which are negatively charged at biological pH values, chitosans are cationic biopolymers under these conditions. The positively charged chitosans are able to interact with oppositely charged surfaces and are therefore used in cosmetic hair and body care products and pharmaceutical preparations. emulsifiers
  • the emulsions can optionally also contain emulsifiers, which represent component (e).
  • emulsifiers are nonionic surfactants from at least one of the following groups:
  • Alkyl and/or alkenyl oligoglycosides having 8 to 22 carbon atoms in the alk(en)yl radical and their ethoxylated analogues;
  • Partial esters of polyglycerol (average degree of self-condensation 2 to 8), polyethylene glycol (molecular weight 400 to 5000), trimethylolpropane, pentaerythritol, sugar alcohols (e.g. sorbitol), alkyl glucosides (e.g. methyl glucoside, butyl glucoside, lauryl glucoside) and polyglucosides (e.g. cellulose) with saturated and/or unsaturated, linear or branched fatty acids having 12 to 22 carbon atoms and/or hydroxycarboxylic acids having 3 to 18 carbon atoms and their adducts with 1 to 30 moles of ethylene oxide;
  • block copolymers e.g., polyethylene glycol-30 dipolyhydroxystearates
  • Polymer emulsifiers e.g. Pemulen types (TR-1JR-2) from Goodrich or Cosmedia®
  • Alkoxylates The addition products of ethylene oxide and/or propylene oxide with fatty alcohols, fatty acids, alkylphenols or castor oil are known, commercially available products. These are homologous mixtures whose average degree of alkoxylation corresponds to the ratio of the amounts of ethylene oxide and/or propylene oxide and Substrate with which the addition reaction is carried out corresponds. C12 / 1 & - Fatty acid mono- and diesters of addition products of ethylene oxide to glycerol are known as moisturizing agents for cosmetic preparations.
  • Alkyl and/or alkenyl oligoglycoside Alkyl and/or alkenyl oligoglycosides, their preparation and their use are known from the prior art. They are produced in particular by reacting glucose or oligosaccharides with primary alcohols having 8 to 18 carbon atoms.
  • the glycoside residue both monoglycosides, in which a cyclic sugar residue is glycosidically bonded to the fatty alcohol, and oligomeric glycosides with a degree of oligomerization of preferably up to about 8 are suitable.
  • the degree of oligomerization is a statistical mean value which is based on a homolog distribution customary for such technical products.
  • Sorbitan Esters Als Sorbitanester Arlington Sorbitanmonoisostearat, Sorbitan- sesquiisostearat, Sorbitan-diisostearat, Sorbitantriisostearat, Sorbitanmonooleat, Sorbitan- sesquioleat, Sorbitan-dioleat, Sorbitantrioleat, Sorbitanmonoerucat, Sorbitansesquierucat, Sorbitandierucat, Sorbitantrierucat, Sorbitanmonoricinoleat, Sorbitansesquiricinoleat, Sor- bitandiricinoleat, Sorbitantriricinoleat, Sorbitanmonohydroxystearat, Sorbitan- sesquihydroxystearat , sorbitan dihydroxystearate, sorbitan trihydroxystearate, sorbitan mono tartrate, sorbitan sesqui tartrate, sorbitan di tartrate, sorbitan tri tart
  • Polyglycerol esters are polyglyceryl-2 dipolyhydroxystearate (Dehymuls® PGPH), polyglycerol-3-diisostearate (Lameform® TGI), polyglyceryl-4 isostearate (Isolan® Gl 34), polyglyceryl-3 oleate, diisostearoyl polyglyceryl- 3 Diisostearate (Isolan® PDI), Polyglyceryl-3 Methylglucose Distearate (Tego Care® 450), Polyglyceryl-3 Beeswax (Cera Bellina®), Polyglyceryl-4 Caprate (Polyglycerol Caprate T2010/90), Polyglyceryl-3 Cetyl Ether (Chimexane® NL), polyglyceryl-3 distearate (C
  • polystyrene resin examples include the mono-, di- and triesters of trimethylolpropane or pentaerythritol with lauric acid, coconut fatty acid, tallow fatty acid, palmitic acid, stearic acid, oleic acid, behenic acid and the like, optionally reacted with 1 to 30 moles of ethylene oxide.
  • Anionic emulsifiers are aliphatic fatty acids having 12 to 22 carbon atoms, such as palmitic acid, stearic acid or behenic acid, and dicarboxylic acids having 12 to 22 carbon atoms, such as azelaic acid or sebacic acid.
  • zwitterionic surfactants are those surface-active compounds which contain at least one quaternary ammonium group and at least one carboxylate and one sulfonate group in the molecule.
  • Particularly suitable zwitterionic surfactants are the so-called betaines, such as the N-alkyl-N,N-dimethylammonium glycinates, for example coconut alkyldimethylammonium glycinate, N-acylaminopropyl-N,N-dimethylammonium glycinates, for example cocoacylaminopropyldimethylammonium glycinate, and 2-alkyl-3-carboxylmethyl -3-Hydroxyethylimidazoline each having 8 to 18 carbon atoms in the alkyl or acyl group and the cocoacylaminoethylhydroxyethylcarboxymethylglycinate.
  • betaines such as the N-alkyl-N,N-dimethylammonium glycinates, for example coconut alkyldimethylammonium glycinate, N-acylaminopropyl-N,N-dimethylammonium gly
  • fatty acid amide derivative known under the CTFA name Cocamidopropyl Betaine is particularly preferred.
  • suitable emulsifiers are ampholytic surfactants.
  • Ampholytic surfactants are surface-active compounds which contain at least one free amino group and at least one --COOH or --SO.sub.3 H group in addition to a C.sub.s /i.s.-alkyl or acyl group in the molecule and are capable of forming inner salts.
  • ampholytic surfactants are N-alkylglycines, N-alkylpropionic acids, N-alkylaminobutyric acids, N-alkyliminodipropionic acids, N-hydroxyethyl-N-alkylamidopropylglycines, N-alkyltaurines, N-alkylsarcosines, 2-alkylaminopropionic acids and alkylaminoacetic acids, each with about 8 to 18 carbon atoms in the alkyl group.
  • Particularly preferred ampholytic surfactants are N-cocoalkylaminopropionate, cocoacylaminoethylaminopropionate and Ci 2/18 -acylsarcosine.
  • cationic surfactants are also suitable as emulsifiers, with those of the esterquat type, preferably methyl-quaternized difatty acid triethanolamine ester salts, being particularly preferred. thickener
  • the thickeners that represent the optional component (f) can be selected from the group formed by Aerosil types (hydrophilic silicic acids), polysaccharides, in particular xanthan gum, guar guar, agar-agar, Alginates and tyloses, carboxymethyl cellulose and hydroxyethyl and hydroxypropyl cellulose, also high molecular weight polyethylene glycol mono- and diesters of fatty acids, polyacrylates (e.g. Carbopole® and Pemulen types from Goodrich; Synthalene® from Sigma; Keltrol types from Kelco; Sepigel types from Seppic; Salcare grades from Allied Colloids), polyacrylamides, polymers, polyvinyl alcohol and polyvinylpyrrolidone.
  • Aerosil types hydrophilic silicic acids
  • polysaccharides in particular xanthan gum, guar guar, agar-agar, Alginates and tyloses, carboxymethyl cellulose and hydroxyeth
  • Bentonites such as Bentone® Gel VS-5PC (Rheox), which is a mixture of cyclopentasiloxane, disteardimonium hectorite and propylene carbonate, have also proven particularly effective.
  • Surfactants such as ethoxylated fatty acid glycerides, esters of fatty acids with polyols such as pentaerythritol or trimethylolpropane, fatty alcohol ethoxylates with a narrow homolog distribution or alkyl oligoglucosides and electrolytes such as sodium chloride and ammonium chloride are also suitable.
  • the emulsions as described above are preferably Pickering emulsions.
  • This is a system that is stabilized by solid particles (here: microcrystalline fibers) that adsorb at the interface between the two phases.
  • This type of emulsion was made according to S.U. Pickering, who described the phenomenon in 1907.
  • S.U. Pickering who described the phenomenon in 1907.
  • solid particles are added to the mixture, they bind to the surface of the interface and prevent the droplets from coalescing, making the emulsion more stable.
  • Emulsions are preferably used which
  • the emulsions form the matrix, which still has to be cured. This is preferably done by coacervation, in particular by dripping in a hardening or precipitation bath, for example by imparting vibration to the emulsion with the aid of an oscillating membrane and then dripping through at least one nozzle, as described for example in EP 1413238 A1 (COGNIS).
  • COGNIS EP 1413238 A1
  • Corresponding apparatuses are available, for example, from Rieter Automatic GmbH.
  • alginic acid or chitosan or their salts are used as gel formers.
  • the hardening or precipitation bath contains a cationic compound, for example calcium ions. If a cationic gelling agent such as chitosan is used, the bath must contain an anionic compound such as alginate.
  • microcapsules with an average diameter of preferably 1 to 3 mm are obtained. It is advisable to sieve the capsules to ensure an even size distribution.
  • the microcapsules thus obtained can have any shape within the production-related limits, but are preferably essentially spherical.
  • the present invention also encompasses detergent preparations which contain the active ingredient capsules according to the invention.
  • These preparations are, for example, soap bases, bar soaps, syndet soaps, liquid soaps, cream soaps and the like intended for body cleansing.
  • the product types mentioned to which the capsules are to be added are collectively referred to as detergent bases.
  • the detergent base may contain the capsules of the invention in amounts of from about 0.5% to about 5% by weight, preferably from about 1% to about 2% by weight.
  • the detergent base essentially consists of a surfactant or a surfactant mixture, which in turn is preferably composed of anionic and mixtures of anionic and amphoteric surfactants.
  • the detergent base can contain vegetable oils and the components that are also part of the above be called emulsions, so mainly emulsifiers, thickeners, perfumes and dyes.
  • anionic and amphoteric (also called zwitterionic) surfactants forming component (a) include: mandelamidopropylamine oxide, mandelamidopropylbetaine, aminopropyllaurylglutamine, ammonium C12-15 alkyl sulfate, ammonium C12-16 alkyl sulfate, ammonium capryth sulfate, Ammonium Cocomonoglyceride Sulfate, Ammonium Coco Sulfate, Ammonium Cocoyl Isethionate, Ammonium Cocoyl Sarcosinate, Ammonium C12-15 Pareth Sulfate, Ammonium C9-10 Perfluoroalkylsulfonates, Ammonium Dinonyl Sulfosuccinate, Ammonium Dodecylbenzenesulfonate, Ammonium Isostearate, Ammonium Laureth-6 Carboxylate, Ammonium Laureth-8 Carboxylate, Ammonium
  • Capryloamphodipropionate Disodium Capryloylglutamate, Disodium Cetearylsulfosuccinate, Disodium Cetylphenyletherdisulfonate, Disodium Cetyl Sulfosuccinate, Disodium Cocamido MEA-Sulfosuccinate, Disodium Cocamido MIPA PEG-4 Sulfosuccinate, Disodium Cocamido MIPA-Sulfosuccinate, Disodium Cocamido PEG-3 Sulfosuccinate, Disodium Coceth-3 Sulfo succinate, disodium cocoamphocarboxyethylhydroxypropylsulfonate, disodium cocoampho- diacetate, disodium cocoamphodipropionate, disodium coco-glucoside sulfosuccinate, disodium coco sulfosuccinate, disodium cocoyl butyl gluceth-10 sulfosuccinate, disodium
  • PEG/PPG-150/35 Copolymer PEG/PPG-160/30 Copolymer, PEG/PPG-190/60 Copolymer,
  • PEG/PPG-200/40 Copolymer PEG/PPG-300/55 Copolymer, PEG/PPG-20/22 Methyl Ether Dimethicone, PEG-26-PPG-30 Phosphate, PEG/PPG-4/2 Propyl Heptyl Ether, PEG/PPG -6/2 propyl heptyl ether, PEG-7/PPG-2 propyl heptyl ether, PEG/PPG-8/2 propyl heptyl ether, PEG/PPG- 10/2 propyl heptyl ether, PEG/PPG-14/2 propyl heptyl ether, PEG/PPG-40 /2 Propylheptyl Ether, PEG/PPG-10/2 Ricinoleate, PEG/PPG-32/3 Ricinoleate, PEG-55 Propylene Glycol Oleate, PEG-25 Propylene Glycol Stearate, PEG-75 Propylene Glycol Stearate,
  • Caproyl methyl taurate sodium caprylate, sodium capryleth-2-carboxylate, sodium capryleth-9-carboxylate, sodium capryloamphoacetate, sodium
  • Cocoglyceryl Ether Sulfonate Sodium Coco/Hydrogenated Tallow Sulfate, Sodium Cocoiminodiacetate, Sodium Cocomonoglyceride Sulfate, Sodium Cocomonoglyceride Sulfonate, Sodium Coco PG-Dimonium Chloride Phosphate, Sodium Coco Sulfate, Sodium Cocoyl Sulfoacetate, Sodium Cocoyl Alaninate , Sodium Cocoyl Amino Acids, Sodium Cocoyl Collagen Amino Acids, Sodium Cocoyl Glutamate, Sodium Cocoyl Glutamate, Sodium Cocoyl Glycinate, Sodium Cocoyl/Hydrogenated Tallow Glutamate, Sodium Cocoyl Hydrolyzed Collagen, Sodium Cocoyl Hydrolyzed Keratin, Sodium Cocoyl Hydrolyzed Rice Protein, Sodium Cocoyl Hydrolyzed Silk, Sodium Cocoyl Hydrolyzed Soy Protein, Sodium Cocoyl Hydrolyzed
  • Cocoyl/Palmoyl/Sunfloweroyl Glutamate Sodium Cocoyl Proline, Sodium Cocoyl Sarcosinate, Sodium Cocoyl Taurate, Sodium Cocoyl Threoninate, Sodium Cocoyl Wheat Amino Acids, Sodium C12-14 Olefin Sulphonate, Sodium C14-16 Olefin Sulfonate, Sodium C14-18 Olefin Sulfonate, Sodium C16-18 Olefin Sulfonate, Sodium Cornamphopropionate, Sodium Cottonseedamphoacetate, Sodium C13-15 Pareth-8-Butyl Phosphate, Sodium C9-II Pareth- 6-Carboxylate, Sodium Cll-15 Pareth-7 Carboxylate, Sodium C12-13 Pareth-5 Carboxylate, Sodium C12-13 Pareth-8 Carboxylate, Sodium C12-13 Pareth-12 carboxylate, sodium C12- 15 pareth-6 carboxylate, sodium C12-15 pareth
  • Lauryl Glucoside Crosspolymer Sodium Hydroxystearate, Sodium Isostearate, Sodium Isosteareth-6-Carboxylate, Sodium Isosteareth- 11 Carboxylate, Sodium Isostearoamphoacetate, Sodium Isostearoamphopropionate, Sodium N- Isostearoyl Methyltaurate, Sodium Laneth Sulfate, Sodium Lanolate, Sodium Lardate, Sodium Lauramido Diacetate, Sodium Lauraminopropionate, Sodium laurate, Sodium laureth-3 carboxylate, Sodium laureth-4 carboxylate, Sodium laureth-5 carboxylate, Sodium laureth-6 carboxylate, Sodium laureth- 8 carboxylate, Sodium laureth-11 carboxylate, Sodium Laureth-12 carboxylate, sodium laureth-13 carboxylate, sodium laureth-14 carboxylate, sodium laureth-16 carboxylate, sodium laureth-17 carboxylate, sodium laure
  • Preferred anionic surfactants are one or more compounds selected from the group consisting of sodium laureth sulfate, sodium lauryl sulfate, sodium/potassium stearate, sodium/potassium oleate, sodium/potassium palmitate, sodium/potassium palmate, sodium/potassium palm kernelate, sodium/ Potassium Linoleate, Sodium/Potassium Laurate, Sodium/Potassium Myristate, Sodium/Potassium Caprylate, Sodium/Potassium Caprate, Sodium/Potassium Cocoate, Sodium/Potassium C14-16 Olefin Sulfonate, Sodium/Potassium Tallowate, Sodium/Potassium Lauroyl Isethionate, Sodium/potassium isethionate, coconut acid, coconut fatty acid C12-18, palm acid, palm kernel acid, stearic acid, lauric acid and mixtures thereof.
  • amphoteric surfactants include cocamidopropyl betaine, sodium cocoamphoacetate, and mixtures thereof.
  • Another subject of the invention relates to a method for producing a detergent preparation comprising or consisting of the following steps:
  • Incorporation means that the capsules are stirred into the base formulation with the necessary care either directly or after redispersion in a suitable solvent and are distributed homogeneously therein without the capsules mechanically breaking.
  • Example 1 Active ingredient capsules based on Aigmat
  • phase A The components of phase A were placed in water and processed into a homogeneous pre-emulsion. Then the emulsifier and the carrier (phase B) were added and also homogenized with stirring. In the third step, phase C was added and the carrier was loaded with the dye particles.
  • the composition of the overall mixture is given in Table 1.
  • composition of active ingredient capsules (quantities as % by weight)
  • Example 1 was repeated.
  • the composition of the overall mixture is given in Table 2.
  • composition of active ingredient capsules (quantities as % by weight) The mixture was then dropped into a bath consisting of a 30% strength by weight aqueous calcium chloride solution, during which the capsules hardened. After about 30 minutes, the intensely red colored capsules were filtered off and dried. Thereafter they were ready for incorporation into a detergent base.
  • phase A The components of phase A were placed in water and processed into a homogeneous pre-emulsion.
  • the emulsifier and the carrier (phase B) were then added and also homogenized with stirring.
  • phase C was added and the carrier was loaded with the dye particles.
  • Table 3 The composition of the overall mixture is given in Table 3.
  • Liquid soap (amounts in % by weight)
  • Liquid soap (amounts in % by weight)
  • Body cleansers (amounts in % by weight)
  • Liquid soap (amounts as % by weight)

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Abstract

The invention relates to novel active substance capsules which are or can be obtained by (i) providing an aqueous emulsion containing (a) at least one microcrystalline fiber, (b) at least one active substance, (c) at least one dye and (d) at least one gel former; (ii) atomizing the emulsion in a curing bath into droplets to form capsules; and (iii) subsequently separating and optionally drying the capsules.

Description

Wi rkstof f ka psel n Active ingredient capsules
GEBIET DER ERFINDUNG FIELD OF THE INVENTION
[0001] Die vorliegende Erfindung befindet sich auf dem Gebiet der Detergenszubereitungen und betrifft Wirkstoffkapseln mit stabil eingearbeiteten Farbstoffen. The present invention is in the field of detergent preparations and relates to active ingredient capsules with stably incorporated dyes.
TECHNOLOGISCHER HINTERGRUND TECHNOLOGICAL BACKGROUND
[0002] Viele Wirkstoffe benötigen nach der Applikation auf der Haut eine gewisse Zeit um Ihre Wirkung vollständig entfalten zu können. Hier spielen verschiedenste Faktoren wie z.B Bioverfügbarkeit, lipophile Eigenschaften, Konzentration, Permeabilität der Haut, galenische Effekte und viele weitere eine Rolle. Im Rahmen von Neuentwicklungen sind der Schutz der Wirkstoffeigenschaften, die gleichmäßige Verteilung und die visuelle Wahrnehmung des Wirkkomplexes als auch die taktilen und visuellen Indikation der Freisetzung und der Wir kung beim Endkunden von besonderer Bedeutung. Ein Beispiel für die gewünschte Funk tion eines solchen Produktes wäre ein Matrixpartikel mit einem antibakteriellen Wirkstoff in einer Flüssigseife. Während der Applikation beim Endkunden soll der Matrix Partikel durch Solvatation bzw. mechanische Kraft zerstört und der Wirkstoff freigesetzt werden. Um dem Endkunden neben der taktilen Wahrnehmung auch einen visuellen Effekt liefern zu können, wird zusätzlich ein Farbstoff eingesetzt, dessen Freisetzung als Indikator für eine hinreichend gründliche Anwendung dient. [0002] Many active ingredients require a certain amount of time after application to the skin in order to be able to develop their full effect. A wide variety of factors such as bioavailability, lipophilic properties, concentration, permeability of the skin, galenic effects and many others play a role here. In the context of new developments, the protection of the properties of the active ingredient, the even distribution and the visual perception of the active complex as well as the tactile and visual indication of the release and the effect on the end customer are of particular importance. An example of the desired function of such a product would be a matrix particle with an antibacterial agent in a liquid soap. During the application at the end customer, the matrix particle should be destroyed by solvation or mechanical force and the active substance should be released. In order to be able to provide the end customer with a visual effect in addition to the tactile perception, a dye is also used, the release of which serves as an indicator for a sufficiently thorough application.
[0003] Die im Stand der Technik verfügbaren Verkapselungsverfahren haben sich als unge eignet erwiesen, die aktuellen Anforderungen zu erfüllen, da das Netzwerk der verwendeten Hydrokolloide nicht die nötige Diffusionsstabilität aufweist und die in der Kapsel enthaltenen Wirk- und Farbstoffe sehr rasch ausbluten. Die mechanische Kraft während einer Handwä sche reicht zudem nicht aus, um den Wirkstoff aus den Kapseln des Stands der Technik ent sprechend zeitnah gesteuert freizusetzen. The encapsulation processes available in the prior art have proven to be unsuitable for meeting current requirements, since the network of hydrocolloids used does not have the necessary diffusion stability and the active ingredients and dyes contained in the capsule bleed out very quickly. In addition, the mechanical force during a hand wash is not sufficient to release the active substance from the capsules of the prior art in a timely and controlled manner.
STAND DER TECHNIK STATE OF THE ART
[0004] Kern-Hülle-Kapseln, die mikrokristalline Cellulose im Kern enthalten sind aus dem Stand der Technik hinreichend bekannt, nämlich beispielsweise aus Core-shell capsules containing microcrystalline cellulose in the core are well known from the prior art, namely, for example
• WO 1999 042087 A2 (EGYPT) • WO 1999 042087 A2 (EGYPT)
• WO 2006 047931 Al (GUOLIAN) • WO 2006 047931 A1 (GUOLIAN)
• WO 2012 027968 Al (CHNGDU UNIVERSITY) • WO 2015 172608 Al (SHANGHAI SPRINGTANG) • WO 2012 027968 Al (CHNGDU UNIVERSITY) • WO 2015 172608 Al (SHANGHAI JUMPING TANG)
• WO 2017 051362 Al (CASI) • WO 2017 051362 A1 (CASI)
• WO 2020 098795 Al (HUTCHISON) • WO 2020 098795 A1 (HUTCHISON)
• US 2003 0500312 AA (NOVO NORDISK) • US 2003 0500312AA (NOVO NORDISK)
• US 2018 072624 AA (SHENGTHEN UNIVERSITY) • US 2018 072624 AA (SHENGTHEN UNIVERSITY)
[0005] Aus der WO 2017 107628 Al (GUANGDONG UNIVERSITY) sind zudem Chitosankap- seln bekannt, die mikrokristalline Cellulose in der Kapselhülle enthalten. [0005] WO 2017 107628 A1 (GUANGDONG UNIVERSITY) also discloses chitosan capsules which contain microcrystalline cellulose in the capsule shell.
AUFGABE DER ERFINDUNG OBJECT OF THE INVENTION
[0006] Daher hat die Aufgabe der vorliegenden Erfindung darin bestanden, mit Wirkstoffen und Farbstoffen beladene Kapseln zur Verfügung zu stellen, bei denen die Wirk- und Farb stoffe stabil eingearbeitet sind, so dass kein Ausbluten stattfindet. Zudem sollten die Kapseln bruchstabil sein, so dass es schon einer einreichend großen oder länger anhaltenden mecha nischen Krafteinwirkung bedarf, bis sie aufbrechen und sowohl den Farbstoff als auch den Wirkstoff freisetzen. Schließlich sollten die Kapseln tensidstabil sein, d.h. die Hülle sollte sich auch in einer hochtensidhaltigen Umgebung, wie beispielsweise einer Seifenbasis oder einer Creme nicht auflösen. [0006] The object of the present invention was therefore to provide capsules loaded with active ingredients and dyes, in which the active ingredients and dyes are stably incorporated, so that no bleeding takes place. In addition, the capsules should be resistant to breakage, so that a sufficiently large or prolonged mechanical force is required before they break open and release both the dye and the active ingredient. Finally, the capsules should be surfactant-stable, i.e. the shell should not disintegrate even in an environment containing a high level of surfactants, such as a soap base or a cream.
BESCHREIBUNG DER ERFINDUNG DESCRIPTION OF THE INVENTION
[0007] Ein erster Gegenstand der Erfindung betrifft Wirkstoffkapseln, die dadurch erhältlich sind oder erhalten werden, indem man A first object of the invention relates to active ingredient capsules that can be obtained or obtained by
(i) eine wässrige Emulsion bereitstellt, enthaltend (i) providing an aqueous emulsion containing
(a) wenigstens eine mikrokristalline Faser, (a) at least one microcrystalline fiber,
(b) wenigstens einen Wirkstoff, (b) at least one active substance,
(c) wenigstens einen Farbstoff und (c) at least one dye and
(d) wenigstens einen Gelbildner; (d) at least one gelling agent;
(ii) die Emulsion in ein Härtungsbad unter Ausbildung von Kapseln vertropft und (ii) dripping the emulsion into a hardening bath to form capsules and
(iii) die Kapseln anschließend abtrennt und gegebenenfalls trocknet. (iii) subsequently separating the capsules and optionally drying them.
[0008] Ein weiterer Gegenstand der Erfindung betrifft ein analoges Herstellverfahren, umfas send oder bestehend aus den folgenden Schritten: Another subject of the invention relates to an analogous production process, comprising or consisting of the following steps:
(i) Bereitstellen einer wässrigen Emulsion, enthaltend (i) providing an aqueous emulsion containing
(a) wenigstens eine mikrokristalline Faser, (a) at least one microcrystalline fiber,
(b) wenigstens einen Wirkstoff, (c) wenigstens einen Farbstoff und (b) at least one active substance, (c) at least one dye and
(d) wenigstens einen Gelbildner; (d) at least one gelling agent;
(ii) Vertropfen der Emulsion in ein Härtungsbad unter Ausbildung von Kapseln; und(ii) dripping the emulsion into a hardening bath to form capsules; and
(iii) Abtrennen und gegebenenfalls Trocknen der Kapseln. (iii) separating and optionally drying the capsules.
[0009] Überraschenderweise wurde gefunden, dass sich mikrokristalline Fasern, speziell mik rokristalline Cellulose mit Wirkstoffen beladen und mit Farbstoffen versiegeln und so stabil in eine Kapselmatrix einarbeiten lassen. Dies ist insbesondere dann möglich, wenn der Durch messer der Farbstoffpartikel um den Faktor 10 bis 100 kleiner ist als die maximale Länge der einzelnen Fasern. Nachdem im ersten Schritt die Faser mit dem Wirkstoff beladen wird, er folgt im zweiten Schritt die Versiegelung der Faser durch den Farbstoff. Die Kapseln werden durch Koazervation in einem Härtungs- oder Fällungsbad hergestellt und erweisen sich nicht nur als ausgesprochen bruchfest, sondern auch als tensidstabil. Dies bedeutet, dass man nach Einarbeitung beispielsweise in eine Seifenbasis schon eine gewisse Zeit benötigt, bis die Kap seln durch mechanische Beanspruchung aufplatzen und den auf dem Träger aufgebrachten Wirkstoff sowie auch die Farbstoffpartikel freisetzen. Diese im Vergleich zu Kapseln, bei de nen der Wirkstoff direkt in der Matrix gelöst und nicht auf einem Träger aufgebracht und stabilisiert vorliegt, geht einher, mit der Absicht, dem Anwender zu einem längeren und gründlicheren Händewaschen anzuhalten, ehe die Farbfreisetzung signalisiert, dass der Reini gungsvorgang jetzt gründlich genug war und beendet werden kann. Surprisingly, it has been found that microcrystalline fibers, specifically microcrystalline cellulose, can be loaded with active ingredients and sealed with dyes and thus be incorporated stably into a capsule matrix. This is particularly possible when the diameter of the dye particles is smaller by a factor of 10 to 100 than the maximum length of the individual fibers. After the fiber is loaded with the active ingredient in the first step, the fiber is sealed with the dye in the second step. The capsules are produced by coacervation in a hardening or precipitation bath and are not only extremely break-resistant, but also surfactant-stable. This means that after incorporation into a soap base, for example, a certain amount of time is required before the capsules burst open due to mechanical stress and release the active substance applied to the carrier as well as the dye particles. Compared to capsules, where the active ingredient is dissolved directly in the matrix and not applied and stabilized to a carrier, this goes hand in hand with the intention of encouraging the user to wash their hands longer and more thoroughly before the color release signals that the The cleaning process was now thorough enough and can be completed.
HERSTELLVERFAHREN MANUFACTURING PROCESS
[0010] Die erfindungsgemäßen Wirkstoffkapseln lassen sich wie oben beschrieben durch Bereitstellen einer Fasern, Wirkstoffe, Farbstoffe und Gelbildner umfassenden Emulsion und Vertropfen der Emulsion in ein Härtungs- oder Fällungsbad gewinnen. Die Kapseln sind nach der Herstelung intensiv gefärbt. Da sie jedoch nur in geringen Mengen den Endprodukten zugesetzt werden, beeinflussen sie deren Farbe erst dann, wenn sie mechanisch aufgebro chen werden und dann vor allem den Schaum stark einfärben. The active substance capsules according to the invention can be obtained as described above by providing an emulsion comprising fibers, active substances, dyes and gel formers and dripping the emulsion into a hardening or precipitation bath. The capsules are intensely colored after production. However, since they are only added to the end products in small amounts, they only affect their color when they are mechanically broken up and then primarily color the foam.
Mikrokristalline Fasern microcrystalline fibers
[0011] Unter „mikrokristallin" sind im Sinne der Erfindung solche Fasern bzw. Faserbruchstü cke zu verstehen, die in ihrer längsten Ausdehnung („Länge") Abmessungen von etwa 100 bis etwa 1.500 pm, vorzugsweise von etwa 200 bis etwa 1.200 pm und insbesondere von etwa 500 bis etwa 1.000 pm aufweisen. Vorzugsweise sind diese Fasern sphärisch geformt. Beson ders bevorzugt ist mikrokristalline Cellulose (MCC, MKZ, E460i), die diese Vorgaben hervorra gend erfüllt. Hierbei handelt es sich um eine weiße, freifließende Cellulose in Pulverform, die in der Lebensmittel- und Pharmaindustrie verwendet wird. MCC dient vor allem als unverdau licher Ballaststoff für kalorienreduzierte Lebensmittel (etwa Salatsoßen, Desserts und Eis- cremes), als Trennmittel oder als Trägerstoff. In der Pharmazie kommt es als Bindemittel und Trägerstoff für die Tablettenherstellung zum Einsatz. Mikrokristalline Cellulose wird beson ders bei der Direkttablettierung verwendet. Hergestellt wird MCC aus verholzten Pflanzentei len, also nicht etwa aus Altpapier. Hierbei wird die Pflanzen-Cellulose mit verdünnter Salzsäu re bei Temperaturen über 100 °C von nichtkristallinen Cellulose-Anteilen befreit. Danach kann wahlweise eine Carboxylierung erfolgen, um die Hydrophilie zu erhöhen. Somit ist akso auch eine mikrokristalline Carboxy- oder Carboxymethylcellulose von der vorliegenden Erfin dung mitumfasst. For the purposes of the invention, “microcrystalline” is understood to mean fibers or fiber fragments that have dimensions of about 100 to about 1,500 μm, preferably from about 200 to about 1,200 μm and in particular in their longest extent (“length”) from about 500 to about 1000 µm. Preferably, these fibers are spherical in shape. Particular preference is given to microcrystalline cellulose (MCC, MKZ, E460i), which meets these requirements extremely well. This is a white, free-flowing powdered cellulose used in the food and pharmaceutical industries. MCC is primarily used as an indigestible dietary fiber for calorie-reduced foods (e.g. salad dressings, desserts and ice cream creams), as a release agent or as a carrier. In pharmacy, it is used as a binding agent and carrier for the manufacture of tablets. Microcrystalline cellulose is used in particular in direct tabletting. MCC is made from woody parts of plants, not from waste paper. Here, the vegetable cellulose is freed from non-crystalline cellulose parts with diluted hydrochloric acid at temperatures above 100 °C. Thereafter, optional carboxylation can occur to increase hydrophilicity. Thus, a microcrystalline carboxy- or carboxymethyl cellulose is also included in the present invention.
Wirkstoffe active ingredients
[0012] Grundsätzlich ist die Auswahl der Wirkstoffe, die die Komponente (b) bilden, unkri tisch, da sie sich nur nach dem Einsatzzweck richtet. Besonders bevorzugt sind jedoch Par fümstoffe und/oder antimikrobielle Wirkstoffe. In principle, the selection of the active ingredients that form component (b) is not critical since it depends only on the intended use. However, perfumes and/or antimicrobial agents are particularly preferred.
Parfümstoffe Perfumes
[0013] Als Parfümstoffe seien genannt Gemische aus natürlichen und synthetischen Riechstoffen. Natürliche Riechstoffe sind Extrakte von Blüten (Lilie, Lavendel, Rosen, Jasmin, Neroli, Ylang-Ylang), Stengeln und Blättern (Geranium, Patchouli, Petitgrain), Früchten (Anis, Koriander, Kümmel, Wacholder), Fruchtschalen (Bergamotte, Zitrone, Orangen), Wurzeln (Macis, Angelica, Sellerie, Kardamon, Costus, Iris, Calmus), Hölzern (Pinien-, Sandei-, Guajak-, Zedern-, Rosenholz), Kräutern und Gräsern (Estragon, Le- mongras, Salbei, Thymian), Nadeln und Zweigen (Fichte, Tanne, Kiefer, Latschen), Har zen und Balsamen (Galbanum, Elemi, Benzoe, Myrrhe, Olibanum, Opoponax). Wei terhin kommen tierische Rohstoffe in Frage, wie beispielsweise Zibet und Castoreum. Typische synthetische Riechstoffverbindungen sind Produkte vom Typ der Ester, Ether, Aldehyde, Ketone, Alkohole und Kohlenwasserstoffe. Riechstoffverbindungen vom Typ der Ester sind z.B. Benzylacetat, Phenoxyethylisobutyrat, p-tert.-Bu- tylcyclohexylacetat, Linalylacetat, Dimethylbenzylcarbinylacetat, Phenylethylacetat, Linalylbenzoat, Benzylformiat, Ethylmethylphenylglycinat, Allylcyclohexylpropionat, Styrallylpropionat und Benzylsalicylat. Zu den Ethern zählen beispielsweise Benzylethylether, zu den Aldehyden z.B. die linearen Alkanale mit 8 bis 18 Kohlen stoffatomen, Citral, Citronellal, Citronellyloxyacetaldehyd, Cyclamenaldehyd, Hydro- xycitronellal, Lilial und Bourgeonal, zu den Ketonen z.B. die Jonone, a-Isomethylionon und Methylcedrylketon, zu den Alkoholen Anethol, Citronellol, Eugenol, Isoeugenol, Geraniol, Linalool, Phenylethylalkohol und Terpineol, zu den Kohlenwasserstoffen ge hören hauptsächlich die Terpene und Balsame. Bevorzugt werden jedoch Mischungen verschiedener Riechstoffe verwendet, die gemeinsam eine ansprechende Duftnote erzeugen. Auch ätherische Öle geringerer Flüchtigkeit, die meist als Aro makomponenten verwendet werden, eignen sich als Parfümöle, z.B. Salbeiöl, Kamil lenöl, Nelkenöl, Melissenöl, Minzenöl, Zimtblätteröl, Lindenblütenöl, Wacholderbee renöl, Vetiveröl, Olibanöl, Galbanumöl, Labolanumöl und Lavandinöl. Vorzugsweise werden Bergamotteöl, Dihydromyrcenol, Lilial, Lyral, Citronellol, Phenylethylalkohol, a-Hexylzimtaldehyd, Geraniol, Benzylaceton, Cyclamenaldehyd, Linalool, Boisambrene Forte, Ambroxan, Indol, Hedione, Sandelice, Citronenöl, Mandarinenöl, Orangenöl, Allylamylglycolat, Cyclovertal, Lavandinöl, Muskateller Salbeiöl, ß-Damascone, Gera niumöl Bourbon, Cyclohexylsalicylat, Vertofix Coeur, Iso-E-Super, Fixolide NP, Evernyl, Iraldein gamma, Phenylessigsäure, Geranylacetat, Benzylacetat, Rosenoxid, Romilllat, Irotyl und Floramat allein oder in Mischungen, eingesetzt. Als Aromen kommen bei spielsweise Pfefferminzöl, Krauseminzöl, Anisöl, Sternanisöl, Kümmelöl, Eukalyptusöl, Fenchelöl, Citronenöl, Wintergrünöl, Nelkenöl, Menthol und dergleichen in Frage. [0013] Perfumes which may be mentioned are mixtures of natural and synthetic fragrances. Natural fragrances are extracts of flowers (lily, lavender, rose, jasmine, neroli, ylang-ylang), stems and leaves (geranium, patchouli, petitgrain), fruits (aniseed, coriander, caraway, juniper), fruit peel (bergamot, lemon, oranges), roots (mace, angelica, celery, cardamom, costus, iris, Calmus), wood (pine, sand egg, guaiac, cedar, rosewood), herbs and grasses (tarragon, lemongrass, sage, thyme). ), needles and twigs (spruce, fir, pine, mountain pine), resins and balms (galbanum, elemi, benzoin, myrrh, olibanum, opoponax). Furthermore, animal raw materials are suitable, such as civet and castoreum. Typical synthetic fragrance compounds are products of the ester, ether, aldehyde, ketone, alcohol and hydrocarbon type. Perfume compounds of the ester type are, for example, benzyl acetate, phenoxyethyl isobutyrate, p-tert-butylcyclohexyl acetate, linalyl acetate, dimethylbenzylcarbinyl acetate, phenylethyl acetate, linalyl benzoate, benzyl formate, ethylmethylphenylglycinate, allylcyclohexylpropionate, styrallylpropionate and benzyl salicylate. The ethers include, for example, benzyl ethyl ether, the aldehydes include, for example, the linear alkanals with 8 to 18 carbon atoms, citral, citronellal, citronellyloxyacetaldehyde, cyclamenaldehyde, hydroxycitronellal, lilial and bourgeonal, the ketones include, for example, the ionones, a-isomethylionone and methylcedryl ketone, the alcohols anethole, citronellol, eugenol, isoeugenol, geraniol, linalool, phenylethyl alcohol and terpineol, the hydrocarbons mainly include terpenes and balms. However, preference is given to using mixtures of different fragrances which together have an appealing fragrance note generate. Essential oils of lower volatility, which are mostly used as aroma components, are also suitable as perfume oils, for example sage oil, camomile oil, clove oil, lemon balm oil, mint oil, cinnamon leaf oil, lime blossom oil, juniper berry oil, vetiver oil, olibanum oil, galbanum oil, labolanum oil and lavandin oil. Preferred are bergamot oil, dihydromyrcenol, lilial, lyral, citronellol, phenylethyl alcohol, a-hexylcinnamaldehyde, geraniol, benzylacetone, cyclamenaldehyde, linalool, boisambrene forte, ambroxan, indole, hedione, sandelice, lemon oil, tangerine oil, orange oil, allylamyl glycolate, cyclovertal, lavandin oil, muscatel Sage oil, ß-Damascone, Bourbon geranium oil, cyclohexyl salicylate, Vertofix Coeur, Iso-E-Super, Fixolide NP, Evernyl, Iraldein gamma, phenylacetic acid, geranyl acetate, benzyl acetate, rose oxide, romillate, Irotyl and Floramat alone or in mixtures. Examples of flavors that can be used are peppermint oil, spearmint oil, anise oil, star anise oil, caraway oil, eucalyptus oil, fennel oil, lemon oil, wintergreen oil, clove oil, menthol and the like.
Antimikrobielle Wirkstoffe Antimicrobial Agents
[0014] Geeignete antimikrobielle Mittel können ausgewählt werden aus der Gruppe beste hend aus Benzoesäure und para-Hydroxybenzoesäure, deren Estern und Salzen, Benzylben zoat, Propionsäure und deren Salzen, Salicylsäure und deren Salzen, 2,4-Hexadiensäure (Sor binsäure) und deren Salzen, Lävulinsäure und deren Salzen, Anisinsäure und ihre Salze, Peril- lasäure und ihre Salze, Zimtsäure und ihre Salze, Formaldehyd und Paraformaldehyd, 4- Hydroxybenzaldehyd, ortho-, meta- und para-Anisaldehyd, Zimtaldehyd, Zimtalkohol, 2- Hydroxybiphenylether und seine Salze, 2-Zink-sulfidopyridin-N-oxid, anorganische Sulfite und Bisulfite, Natriumjodat, Chlorbutanolum, 4-Ethylquecksilber-(II)-5-amino-l,3-bis(2- hydroxybenzoesäure), seine Salze und Ester, Dehydracetsäure, Ameisensäure, 1,6-Bis(4- amidino-2-bromphenoxy)-n-hexan und seine Salze, das Natriumsalz der Ethylquecksilber-(II)- thiosalicylsäure, Phenylquecksilber und seine Salze, 10-Undecylensäure und seine Salze, 5- Amino-l,3-bis(2-ethylhexyl)-5-methyl-hexahydropyrimidin, 5-Brom-5-nitro-l,3-dioxan, 2- Brom-2-nitro-l,3-propandiol, 2,4-Dichlorbenzylalkohol, N-(4-Chlorphenyl)-N'-(3,4- dichlorphenyl)-Harnstoff, 4-Chlor-m-kresol, 2,4, 4'-Trichlor-2'-hydroxy-diphenylether, 4- Chlor-3,5-dimethylphenol, l,l'-Methylen-bis-(3-(l-hydroxymethyl-2,4-dioximidazolidin-5- yl)-harnstoff), Poly-(hexamethylendiguanid)-hydrochlorid, (Benzyloxymethoxy)-methanol- hexamethylentetramin, l-(3-Chlorallyl)-3,5,7-triaza-l-azonia-adamantan-chlorid, l-(4- Chlorphenoxy)-l-(lH-imidazol-l-yl)-3,3-dimethyl-2-butanon, l,3-Bis-(hydroxymethyl)-5,5- dimethyl-2,4-imidazolidindion, l,2-Dibrom-2,4-dicyanobutan, 2,2'-Methylen-bis-(6-brom-4- chlorphenol), Bromchlorophen, Mischung aus 5-Chlor-2-methyl-3(2H)-isothiazolinon, 2- Methyl-3(2H)-isothiazolinon und mit Magnesiumchlorid und Magnesiumnitrat, 2-Octyl-2H- isothiazol-3-on, l,2-Benzisothiazol-3(2H)-on, 2-Benzyl-4-chlorphenol, 3-(4-Chlorphenoxy)- 1,2-propandiol (Chlorphenesin), 2-Chloracetamid, Chlorhexidin, Chlorhexidinacetat, Chlorhexidingluconat, Chlorhexidinhydrochlorid, N-Alkyl(C12-Suitable antimicrobial agents can be selected from the group consisting of benzoic acid and para-hydroxybenzoic acid, their esters and salts, benzyl benzoate, propionic acid and their salts, salicylic acid and their salts, 2,4-hexadienoic acid (sorbic acid) and their Salts, levulinic acid and its salts, anisic acid and its salts, perillaic acid and its salts, cinnamic acid and its salts, formaldehyde and paraformaldehyde, 4-hydroxybenzaldehyde, ortho-, meta- and para-anisaldehyde, cinnamaldehyde, cinnamic alcohol, 2-hydroxybiphenyl ether and Its salts, 2-zinc sulfidopyridine N-oxide, inorganic sulfites and bisulfites, sodium iodate, chlorobutanol, 4-ethylmercury(II)-5-amino-1,3-bis(2-hydroxybenzoic acid), its salts and esters, Dehydroacetic acid, formic acid, 1,6-bis(4-amidino-2-bromophenoxy)-n-hexane and its salts, the sodium salt of ethylmercuric(II)-thiosalicylic acid, phenylmercury and its salts, 10-undecylenic acid and its salts, 5 - amino-1,3-bis(2-ethylhexyl)- 5-methyl-hexahydropyrimidine, 5-bromo-5-nitro-1,3-dioxane, 2-bromo-2-nitro-1,3-propanediol, 2,4-dichlorobenzyl alcohol, N-(4-chlorophenyl)-N' -(3,4-dichlorophenyl)urea, 4-chloro-m-cresol, 2,4,4'-trichloro-2'-hydroxydiphenyl ether, 4-chloro-3,5-dimethylphenol, l,l'- methylene bis(3-(l-hydroxymethyl-2,4-dioximidazolidin-5-yl)urea), poly(hexamethylenediguanide) hydrochloride, (benzyloxymethoxy)methanolhexamethylenetetramine, l-(3-chloroallyl)- 3,5,7-triaza-l-azonia-adamantane chloride, l-(4-chlorophenoxy)-l-(lH-imidazol-l-yl)-3,3-dimethyl-2-butanone, l,3- bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione, 1,2-dibromo-2,4-dicyanobutane, 2,2'-methylene-bis(6-bromo-4-chlorophenol), bromochlorophene , mixture of 5-chloro-2-methyl-3(2H)-isothiazolinone, 2- methyl-3(2H)-isothiazolinone and with magnesium chloride and magnesium nitrate, 2-octyl-2H-isothiazol-3-one, l,2- Benzisothiazol-3(2H)-one, 2-Benzyl-4-chlorophenol, 3-(4-Chlorophenoxy)-1,2-propanediol (Chlorphenesin), 2-Chloroacetamide, Chlorhexidine, Chlorhe xidine acetate, Chlorhexidine gluconate, chlorhexidine hydrochloride, N-alkyl(C12-
C22)trimethylammoniumbromid und -chlorid, 4,4-Dimethyl-l,3-oxazolidin, N- Hydroxymethyl-N-(l,3-di(hydroxymethyl)-2, 5-Dioxoimidazolidin-4-yl)-N'- hydroxymethylharnstoff, l,6-Bis(4-amidino-phenoxy)-n-hexan und seine Salze, Glutaralde- hyd, 5-Ethyl-l-aza-3,7-dioxabicyclo(3. 3. 0)octan, 3-(4-Chlorphenoxy)-l,2-propandiol, Hya- mine, Alkyl-(C8-C18)-dimethyl-benzyl-ammoniumchlorid, Alkyl-(C8-C18)-dimethyl-benzyl- ammoniumbromid, Alkyl-(C8-C18)-dimethyl-benzyl-ammonium saccharinat, Benzylhemifor- mal, 3-Iod-2-propinylbutylcarbamat, Natriumhydroxymethyl-aminoacetat oder Natriumhyd- roxymethyl-aminoacetat, Imidazolidinylharnstoff, Diazolidinylharnstoff, Natriumhydroxyme- thylglycinat, DMDM-Hydantoin, Tropolon, (Ethylendioxy)dimethanol, 2-Brom-2- (brommethyl)pentandinitril, N-(3-Aminopropyl)-N-dodecylpropan-l, 3-Diamin, a,a',a"- Trimethyl-l,3,5-triazin-l,3,5(2H,4H,6H)-triethanol, Pyridin-2-thiol-l-oxid, Natriumsalz, Tetra- hydro-1, 3,4,6-Tetrakis(hydroxymethyl)imidazo[4,5-d]imidazol-2,5(lH,3H)-dion, 1,3- Bis(hydroxymethyl)-l-(l,3,4-tris(hydroxy-methyl)-2, 5-Dioxoimidazolidin-4-yl)harnstoff (Dia zolidinylharnstoff), l,3-Bis(hydroxy-methyl)-5,5-dimethylimidazolidin-2,4-dion, 3-Acetyl-2- hydroxy-6-methyl-4H-pyran-4-on, Cetylpyridiumchlorid, Caprylhydroxamsäure, Sorbohydro- xamsäure und deren Gemische; 1,3-Propandiol, Methylpropandiol, 1,2-Pentandiol, 1,2- Hexandiol, 1,2-Octandiol, 1,2-Decandiol, 1,5-Pentandiol, 1,6-Hexandiol, 1,8-Octandiol, 1,2- Decandiol, Ethylhexylglycerin, Hexoxypropan-l,2-diol, Heptoxypropan-l,2-diol, Octoxypro- pan-1, 2-Diol, 3-Phenoxy-Propan-l,2-Diol, 3-Benzyloxy-Propan-l,2-Diol, 3-Phenylethyloxy- Propan-l,2-Diol, 3-Phenylpropyloxy-Propan-l, 2-Diol, 3-Methylbenzyloxy-Propan-l, 2-Diol, Sorbitan Caprylat, Triclosan, Climbazol, Octopirox (l-Hydroxy-4-methyl-6-(2, 4,4- Trimethylpentyl)-2(lH)-pyridon, 2-Aminoethanol), Chitosan, Farnesol, 2-Butyloctansäure, 2- Benzylheptan-l-ol, Glycerinmonolaurat, Bis(2-pyridylthio)Zink-l,l'-dioxid, N,N'-(Decan-l,10- diyldipyridin-l-yl-4-yliden)-dioctan-l-amin-Dihydrochlorid (Octenidin-Dihydrochlorid), Thy mol, Eugenol, Benzylalkohol, 2-Phenyethylalkohol, 3-Phenylpropanol, 2-Phenoxyethanol, 1- Phenoxypropan-2-ol, 3-Phenoxypropanol, Benzyloxymethanol, o-Cymen-5-ol, 4-Hydroxy- acetophenon, 1,2-Pentandiol, 1,2-Hexandiol, 1,2-Octandiol, 1,2-Decandio, 1,2-Dodecandiol, 1,2-Tetradecandiol und Mischungen davon. C22) trimethylammonium bromide and chloride, 4,4-dimethyl-1,3-oxazolidine, N-hydroxymethyl-N-(1,3-di(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl)-N'-hydroxymethyl urea , l,6-bis(4-amidinophenoxy)-n-hexane and its salts, glutaraldehyde, 5-ethyl-l-aza-3,7-dioxabicyclo(3. 3. 0)octane, 3-( 4-chlorophenoxy)-l,2-propanediol, hyamine, alkyl-(C8-C18)-dimethyl-benzyl-ammonium chloride, alkyl-(C8-C18)-dimethyl-benzyl-ammonium bromide, alkyl-(C8-C18) -dimethyl-benzyl-ammonium saccharinate, benzyl hemiformal, 3-iodo-2-propynylbutylcarbamate, sodium hydroxymethyl-aminoacetate or sodium hydroxymethyl-aminoacetate, imidazolidinyl urea, diazolidinyl urea, sodium hydroxymethylglycinate, DMDM-hydantoin, tropolone, (ethylenedioxy)dimethanol, 2 -bromo-2-(bromomethyl)pentanedinitrile, N-(3-aminopropyl)-N-dodecylpropane-1,3-diamine, a,a',a"-trimethyl-1,3,5-triazine-1,3, 5(2H,4H,6H)-triethanol, pyridine-2-thiol-1-oxide, sodium salt, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)imidazo[4,5-d]imidazole-2 ,5(1H,3H)-d ion, 1,3-bis(hydroxymethyl)-1-(1,3,4-tris(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl)urea (diazolidinylurea), 1,3-bis(hydroxy -methyl)-5,5-dimethylimidazolidine-2,4-dione, 3-acetyl-2-hydroxy-6-methyl-4H-pyran-4-one, cetylpyridium chloride, caprylic hydroxamic acid, sorbohydroxamic acid and mixtures thereof; 1,3-propanediol, methylpropanediol, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, 1,5-pentanediol, 1,6-hexanediol, 1,8-octanediol, 1,2-decanediol, ethylhexylglycerol, hexoxypropane-1,2-diol, heptoxypropane-1,2-diol, octoxypropane-1,2-diol, 3-phenoxy-propane-1,2-diol, 3-benzyloxy- Propane-1,2-diol, 3-phenylethyloxy-propane-1,2-diol, 3-phenylpropyloxy-propane-1, 2-diol, 3-methylbenzyloxy-propane-1, 2-diol, sorbitan caprylate, triclosan, climbazole , octopirox (l-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(lH)-pyridone, 2-aminoethanol), chitosan, farnesol, 2-butyloctanoic acid, 2-benzylheptan-l-ol , Glycerol monolaurate, Bis(2-pyridylthio)zinc l,l'-dioxide, N,N'-(Decan-l,10-diyldipyridin-l-yl-4-ylidene)-dioctan-l-amine dihydrochloride (octenidine -dihydrochloride), thymol, eugenol, benzyl alcohol, 2-phenyethyl alcohol, 3-phenylpropanol, 2-phenoxyethanol, 1-phenoxypropan-2-ol, 3-phenoxypropanol, benzyloxymethanol, o-cymen-5-ol, 4-hydroxyacetophenone , 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol , 1,2-decanedio, 1,2-dodecanediol, 1,2-tetradecanediol and mixtures thereof.
[0015] Besonders bevorzugt sind Phenylpropanol, o-Cymen-5-ol, 1,2-Pentandiol, 1,2- Hexandiol, 1,2-Octandiol, 1,2-Decandiol, 4-Hydroxyacetophenon und deren Mischungen. Phenylpropanol, o-cymen-5-ol, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, 4-hydroxyacetophenone and mixtures thereof are particularly preferred.
Farbpigmente color pigments
[0016] Die Auswahl der Farbpigmente, die die Gruppe (c) bilden ist ebenfalls weitgehend unkritisch, da sich deren Einsatz im Wesentlichen nach der gewünschten Farbe richtet. In Be tracht kommen beispielsweise: The selection of the color pigments that form group (c) is also largely uncritical, since their use depends essentially on the desired color. For example:
[0017] Vorzugsweise werden als Farbstoffe Pigmente einsetzt, deren Partikeldurchmesser um den Faktor 10 bis 100 und insbesondere um den Faktor 20 bis 50 kleiner ist, als die Länge der mikrokristallinen Fasern. Pigments are preferably used as dyes, the particle diameter of which is smaller by a factor of 10 to 100 and in particular by a factor of 20 to 50 than the length of the microcrystalline fibers.
Gelbildner gelling agent
[0018] Bevorzugte Gelbildner im Rahmen der Erfindung sind Substanzen, die in wässriger Lösung bei Temperaturen oberhalb von 40° C Gele bilden können. Typische Beispiele für sol- che Gelbildner sind Heteropolysaccharide und Proteine. Bevorzugte thermogelierende Hete ropolysaccharide sind Agarosen, die in Form des aus Rotalgen erhältlichen Agar-Agar auch zusammen mit bis zu 30 Gew.-% nicht gelbildender Agaropektine vorliegen können. Haupt bestandteil der Agarosen sind lineare Polysaccharide aus Galactose und 3,6-Anhydro-L- Galactose mit abwechselnd 1,3- und 1,4-glykosidischen Bindungen. Die Heteropolysacchari- de haben vorzugsweise ein Molekulargewicht von 110.000 bis 160.000 und sind sowohl ge- ruchs- als auch geschmacksneutral. Geeignete Alternativen sind Pektine, Xanthane (ein schließlich Xanthangummi) und Mischungen davon. Weitere bevorzugte Typen sind solche, die in 1 gew.-%iger wässriger Lösung noch Gele bilden, die unterhalb von 80° C. nicht schmelzen und oberhalb von 40° C. wieder erstarren. Beispiele aus der Gruppe der thermo- gelierenden Proteine sind die verschiedenen Gelatinen. Preferred gel formers within the scope of the invention are substances which can form gels in aqueous solution at temperatures above 40.degree. Typical examples of such gel formers are heteropolysaccharides and proteins. Preferred thermogelling heteropolysaccharides are agaroses, which can also be present in the form of the agar-agar obtainable from red algae together with up to 30% by weight of non-gel-forming agaropectins. The main components of agaroses are linear polysaccharides made from galactose and 3,6-anhydro-L-galactose with alternating 1,3- and 1,4-glycosidic bonds. The heteropolysaccharides preferably have a molecular weight of 110,000 to 160,000 and are both odorless and tasteless. Suitable alternatives are pectins, xanthans (including xanthan gum) and mixtures thereof. Other preferred types are those that still form gels in a 1% by weight aqueous solution, which below 80° C. do not melt and solidify again above 40°C. Examples from the group of thermo-gelling proteins are the various gelatins.
[0019] Im Sinne der vorliegenden Erfindung werden als Gelbildner vorzugsweise Alginsäure oder deren Salze, insbesondere Natriumalginat eingesetzt. Die Alginsäure ist ein Gemisch aus carboxylhaltigen Polysacchariden mit der folgenden idealisierten Monomereinheit: For the purposes of the present invention, alginic acid or its salts, in particular sodium alginate, are preferably used as the gelling agent. Alginic acid is a mixture of carboxyl-containing polysaccharides with the following idealized monomer unit:
[0020] Das mittlere Molekulargewicht der Alginsäure bzw. der Alginate liegt im Bereich von 150.000 bis 250.000. Unter Salzen der Alginsäure und deren vollständigen und teilweisen Neutralisationsprodukten versteht man insbesondere die Alkalimetallsalze, vorzugsweise Natriumalginat ("Algin") sowie die Ammonium- und Erdalkalimetallsalze. Besonders bevor zugt sind Mischalginate, zum Beispiel Natrium/Magnesium- oder Natrium/Calcium-Alginate. In einer alternativen Ausführungsform der Erfindung sind jedoch auch Carboxymethylcellulo- sen und anionische Chitosanderivate, zum Beispiel die Carboxylierungs- und vor allem Succi- nylierungsprodukte, dafür geeignet. [0021] Alternativ können als Gelbildner auch Chitosane eingesetzt werden, Dabei handelt es sich um Biopolymere, die ebenfalls zur Gruppe der Hydrokolloide gehören. Chemisch gese hen handelt es sich um teildeacetylierte Chitine mit unterschiedlichen Molekulargewichten, die folgende - idealisierte - Monomereinheit enthalten: The average molecular weight of alginic acid or alginates is in the range from 150,000 to 250,000. Salts of alginic acid and its complete and partial neutralization products are understood to mean, in particular, the alkali metal salts, preferably sodium alginate ("algin"), and the ammonium and alkaline earth metal salts. Mixed alginates, for example sodium/magnesium or sodium/calcium alginates, are particularly preferred. In an alternative embodiment of the invention, however, carboxymethyl cellulose and anionic chitosan derivatives, for example the carboxylation and especially succinylation products, are also suitable for this. Alternatively, chitosans can also be used as gel formers. These are biopolymers that also belong to the group of hydrocolloids. From a chemical point of view, these are partially deacetylated chitins with different molecular weights, which contain the following - idealized - monomer unit:
[0022] Im Gegensatz zu den meisten Hydrokolloiden, die bei biologischen pH-Werten nega tiv geladen sind, sind Chitosane unter diesen Bedingungen kationische Biopolymere. Die po sitiv geladenen Chitosane sind in der Lage, mit entgegengesetzt geladenen Oberflächen zu interagieren und werden daher in kosmetischen Haar- und Körperpflegeprodukten und pharmazeutischen Zubereitungen eingesetzt. Emulgatoren In contrast to most hydrocolloids, which are negatively charged at biological pH values, chitosans are cationic biopolymers under these conditions. The positively charged chitosans are able to interact with oppositely charged surfaces and are therefore used in cosmetic hair and body care products and pharmaceutical preparations. emulsifiers
[0023] Die Emulsionen können optional weiterhin Emulgatoren, die Bestandteil (e) darstellen, enthalten. Als Emulgatoren kommen beispielsweise nichtionogene Tenside aus mindestens einer der folgenden Gruppen in Frage: The emulsions can optionally also contain emulsifiers, which represent component (e). Examples of suitable emulsifiers are nonionic surfactants from at least one of the following groups:
• Anlagerungsprodukte von 2 bis 30 Mol Ethylenoxid und/ oder 0 bis 5 Mol Propylenoxid an lineare Fettalkohole mit 8 bis 22 C-Atomen, an Fettsäuren mit 12 bis 22 C-Atomen, an Alkylphenole mit 8 bis 15 C-Atomen in der Alkylgruppe sowie Alkylamine mit 8 bis 22 Kohlenstoffatomen im Alkylrest; • Adducts of 2 to 30 moles of ethylene oxide and/or 0 to 5 moles of propylene oxide onto linear fatty alcohols containing 8 to 22 carbon atoms, onto fatty acids containing 12 to 22 carbon atoms, onto alkylphenols containing 8 to 15 carbon atoms in the alkyl group and alkylamines having 8 to 22 carbon atoms in the alkyl radical;
• Alkyl- und/oder Alkenyloligoglykoside mit 8 bis 22 Kohlenstoffatomen im Alk(en)ylrest und deren ethoxylierte Analoga; • Alkyl and/or alkenyl oligoglycosides having 8 to 22 carbon atoms in the alk(en)yl radical and their ethoxylated analogues;
• Anlagerungsprodukte von 1 bis 15 Mol Ethylenoxid an Ricinusöl und/oder gehärtetes Ricinusöl; • adducts of 1 to 15 moles of ethylene oxide with castor oil and/or hydrogenated castor oil;
• Anlagerungsprodukte von 15 bis 60 Mol Ethylenoxid an Ricinusöl und/oder gehärtetes Ricinusöl; • adducts of 15 to 60 moles of ethylene oxide with castor oil and/or hardened castor oil;
• Partialester von Glycerin und/oder Sorbitan mit ungesättigten, linearen oder gesättig ten, verzweigten Fettsäuren mit 12 bis 22 Kohlenstoffatomen und/oder Hydroxycar- bonsäuren mit 3 bis 18 Kohlenstoffatomen sowie deren Addukte mit 1 bis 30 Mol Ethy lenoxid; • Partial esters of glycerol and/or sorbitan with unsaturated, linear or saturated, branched fatty acids having 12 to 22 carbon atoms and/or hydroxycarboxylic acids having 3 to 18 carbon atoms and their adducts with 1 to 30 moles of ethylene oxide;
• Partialester von Polyglycerin (durchschnittlicher Eigenkondensationsgrad 2 bis 8), Po- lyethylenglycol (Molekulargewicht 400 bis 5000), Trimethylolpropan, Pentaerythrit, Zu ckeralkoholen (z.B. Sorbit), Alkylglucosiden (z.B. Methylglucosid, Butylglucosid, Lau- rylglucosid) sowie Polyglucosiden (z.B. Cellulose) mit gesättigten und/oder ungesättig ten, linearen oder verzweigten Fettsäuren mit 12 bis 22 Kohlenstoffatomen und/oder Hydroxycarbonsäuren mit 3 bis 18 Kohlenstoffatomen sowie deren Addukte mit 1 bis 30 Mol Ethylenoxid; • Partial esters of polyglycerol (average degree of self-condensation 2 to 8), polyethylene glycol (molecular weight 400 to 5000), trimethylolpropane, pentaerythritol, sugar alcohols (e.g. sorbitol), alkyl glucosides (e.g. methyl glucoside, butyl glucoside, lauryl glucoside) and polyglucosides (e.g. cellulose) with saturated and/or unsaturated, linear or branched fatty acids having 12 to 22 carbon atoms and/or hydroxycarboxylic acids having 3 to 18 carbon atoms and their adducts with 1 to 30 moles of ethylene oxide;
• Mischester aus Pentaerythrit, Fettsäuren, Citronensäure und Fettalkohol und/oder Mi schester von Fettsäuren mit 6 bis 22 Kohlenstoffatomen, Methylglucose und Polyolen, vorzugsweise Glycerin oder Polyglycerin. • Mixed esters of pentaerythritol, fatty acids, citric acid and fatty alcohol and/or mixed esters of fatty acids having 6 to 22 carbon atoms, methyl glucose and polyols, preferably glycerol or polyglycerol.
• Mono-, Di- und Trialkylphosphate sowie Mono-, Di- und/oder Tri-PEG-alkylphosphate und deren Salze; • mono-, di- and trialkyl phosphates and mono-, di- and/or tri-PEG-alkyl phosphates and their salts;
• Wollwachsalkohole; • wool wax alcohols;
• Polysiloxan-Polyalkyl-Polyether-Copolymere bzw. entsprechende Derivate; • Polysiloxane-polyalkyl-polyether copolymers or corresponding derivatives;
• Block-Copolymere z.B. Polyethylenglycol-30 Dipolyhydroxystearate; • block copolymers, e.g., polyethylene glycol-30 dipolyhydroxystearates;
• Polymeremulgatoren, z.B. Pemulen-Typen (TR-1JR-2) von Goodrich oder Cosmedia®• Polymer emulsifiers, e.g. Pemulen types (TR-1JR-2) from Goodrich or Cosmedia®
SP von Cognis; SP from Cognis;
• Polyalkylenglycole sowie Glycerincarbonat. • Polyalkylene glycols as well glycerol carbonate.
[0024] Im Folgenden werden besonders geeignete Emulgatoren näher erläutert: Particularly suitable emulsifiers are explained in more detail below:
[0025] Alkoxylate. Die Anlagerungsprodukte von Ethylenoxid und/oder von Propylenoxid an Fettalkohole, Fettsäuren, Alkylphenole oder an Ricinusöl stellen bekannte, im Handel er hältliche Produkte dar. Es handelt sich dabei um Homologengemische, deren mittlerer Alko xylierungsgrad dem Verhältnis der Stoffmengen von Ethylenoxid und/ oder Propylenoxid und Substrat, mit denen die Anlagerungsreaktion durchgeführt wird, entspricht. C12/1&- Fettsäuremono- und -diester von Anlagerungsprodukten von Ethylenoxid an Glycerin sind als Rückfettungsmittel für kosmetische Zubereitungen bekannt. Alkoxylates. The addition products of ethylene oxide and/or propylene oxide with fatty alcohols, fatty acids, alkylphenols or castor oil are known, commercially available products. These are homologous mixtures whose average degree of alkoxylation corresponds to the ratio of the amounts of ethylene oxide and/or propylene oxide and Substrate with which the addition reaction is carried out corresponds. C12 / 1 & - Fatty acid mono- and diesters of addition products of ethylene oxide to glycerol are known as moisturizing agents for cosmetic preparations.
[0026] Alkyl- und/oder Alkenyloligoglykosid. Alkyl- und/oder Alkenyloligoglycoside, ihre Herstellung und ihre Verwendung sind aus dem Stand der Technik bekannt. Ihre Herstellung erfolgt insbesondere durch Umsetzung von Glucose oder Oligosacchariden mit primären Alkoholen mit 8 bis 18 Kohlenstoffatomen. Bezüglich des Glycosidrestes gilt, daß sowohl Monoglycoside, bei denen ein cyclischer Zuckerrest glycosidisch an den Fettalkohol gebun den ist, als auch oligomere Glycoside mit einem Oligomerisationsgrad bis vorzugsweise etwa 8 geeignet sind. Der Oligomerisierungsgrad ist dabei ein statistischer Mittelwert, dem eine für solche technischen Produkte übliche Homologenverteilung zugrunde liegt. Alkyl and/or alkenyl oligoglycoside. Alkyl and/or alkenyl oligoglycosides, their preparation and their use are known from the prior art. They are produced in particular by reacting glucose or oligosaccharides with primary alcohols having 8 to 18 carbon atoms. With regard to the glycoside residue, both monoglycosides, in which a cyclic sugar residue is glycosidically bonded to the fatty alcohol, and oligomeric glycosides with a degree of oligomerization of preferably up to about 8 are suitable. The degree of oligomerization is a statistical mean value which is based on a homolog distribution customary for such technical products.
[0027] Partialglyceride. Typische Beispiele für geeignete Partialglyceride sind Hydroxys- tearinsäuremonoglycerid, Hydroxystearinsäurediglycerid, Isostearinsäuremonoglycerid, Isostearinsäurediglycerid, Ölsäuremonoglycerid, Ölsäurediglycerid, Ricinolsäuremoglycerid, Ricinolsäurediglycerid, Linolsäuremonoglycerid, Linolsäurediglycerid, Linolensäuremonogly- cerid, Linolensäurediglycerid, Erucasäuremonoglycerid, Erucasäurediglycerid, Weinsäuremo- noglycerid, Weinsäurediglycerid, Citronensäuremonoglycerid, Citronendiglycerid, Äpfelsäu- remonoglycerid, Äpfelsäurediglycerid sowie deren technische Gemische, die untergeordnet aus dem Herstellungsprozeß noch geringe Mengen an Triglycerid enthalten können. Eben falls geeignet sind Anlagerungsprodukte von 1 bis 30, vorzugsweise 5 bis 10 Mol Ethylenoxid an die genannten Partialglyceride. Partial glycerides. Typische Beispiele für geeignete Partialglyceride sind Hydroxys- tearinsäuremonoglycerid, Hydroxystearinsäurediglycerid, Isostearinsäuremonoglycerid, Isostearinsäurediglycerid, Ölsäuremonoglycerid, Ölsäurediglycerid, Ricinolsäuremoglycerid, Ricinolsäurediglycerid, Linolsäuremonoglycerid, Linolsäurediglycerid, Linolensäuremonogly- cerid, Linolensäurediglycerid, Erucasäuremonoglycerid, Erucasäurediglycerid, Weinsäuremo- noglycerid, Weinsäurediglycerid, Citronensäuremonoglycerid, Citronendiglycerid, Äpfelsäu- remonoglyceride, malic acid diglyceride and technical mixtures thereof, which may also contain small amounts of triglyceride from the manufacturing process. Adducts of 1 to 30, preferably 5 to 10, moles of ethylene oxide onto the partial glycerides mentioned are also suitable.
[0028] Sorbitanester. Als Sorbitanester kommen Sorbitanmonoisostearat, Sorbitan- sesquiisostearat, Sorbitan-diisostearat, Sorbitantriisostearat, Sorbitanmonooleat, Sorbitan- sesquioleat, Sorbitan-dioleat, Sorbitantrioleat, Sorbitanmonoerucat, Sorbitansesquierucat, Sorbitandierucat, Sorbitantrierucat, Sorbitanmonoricinoleat, Sorbitansesquiricinoleat, Sor- bitandiricinoleat, Sorbitantriricinoleat, Sorbitanmonohydroxystearat, Sorbitan- sesquihydroxystearat, Sorbitandihydroxystearat, Sorbitantrihydroxystearat, Sorbitanmono- tartrat, Sorbitansesqui-tartrat, Sorbitanditartrat, Sorbitantritartrat, Sorbitanmonocitrat, Sor- bitansesquicitrat, Sorbitandicitrat, Sorbitantricitrat, Sorbitanmonomaleat, Sorbitansesqui- maleat, Sorbitan-dimaleat, Sorbitantrimaleat sowie deren technische Gemische. Ebenfalls geeignet sind Anlagerungsprodukte von 1 bis 30, vorzugsweise 5 bis 10 Mol Ethylenoxid an die genannten Sorbitanester. [0029] Polyglycerinester. Typische Beispiele für geeignete Polyglycerinester sind Polygly- ceryl-2 Dipolyhydroxystearate (Dehymuls® PGPH), Polyglycerin-3-Diisostearate (Lameform® TGI), Polyglyceryl-4 Isostearate (Isolan® Gl 34), Polyglyceryl-3 Oleate, Diisostearoyl Polygly- ceryl-3 Diisostearate (Isolan® PDI), Polyglyceryl-3 Methylglucose Distearate (Tego Care® 450), Polyglyceryl-3 Beeswax (Cera Bellina®), Polyglyceryl-4 Caprate (Polyglycerol Caprate T2010/90), Polyglyceryl-3 Cetyl Ether (Chimexane® NL), Polyglyceryl-3 Distearate (Cremo- phor® GS 32) und Polyglyceryl Polyricinoleate (Admul® WOL 1403) Polyglyceryl Dimerate Isostearate sowie deren Gemische. Beispiele für weitere geeignete Polyolester sind die gege benenfalls mit 1 bis 30 Mol Ethylenoxid umgesetzten Mono-, Di- und Triester von Trimethyl- olpropan oder Pentaerythrit mit Laurinsäure, Kokosfettsäure, Talgfettsäure, Palmitinsäure, Stearinsäure, Ölsäure, Behensäure und dergleichen. Sorbitan Esters. Als Sorbitanester kommen Sorbitanmonoisostearat, Sorbitan- sesquiisostearat, Sorbitan-diisostearat, Sorbitantriisostearat, Sorbitanmonooleat, Sorbitan- sesquioleat, Sorbitan-dioleat, Sorbitantrioleat, Sorbitanmonoerucat, Sorbitansesquierucat, Sorbitandierucat, Sorbitantrierucat, Sorbitanmonoricinoleat, Sorbitansesquiricinoleat, Sor- bitandiricinoleat, Sorbitantriricinoleat, Sorbitanmonohydroxystearat, Sorbitan- sesquihydroxystearat , sorbitan dihydroxystearate, sorbitan trihydroxystearate, sorbitan mono tartrate, sorbitan sesqui tartrate, sorbitan di tartrate, sorbitan tri tartrate, sorbitan mono citrate, sorbitan sesquicitrate, sorbitan citrate, sorbitan tricitrate, sorbitan monomaleate, sorbitan sesquimaleate, sorbitan dimaleate, sorbitan trimaleate and technical mixtures thereof. Addition products of 1 to 30, preferably 5 to 10, moles of ethylene oxide onto the sorbitan esters mentioned are also suitable. Polyglycerol esters. Typical examples of suitable polyglycerol esters are polyglyceryl-2 dipolyhydroxystearate (Dehymuls® PGPH), polyglycerol-3-diisostearate (Lameform® TGI), polyglyceryl-4 isostearate (Isolan® Gl 34), polyglyceryl-3 oleate, diisostearoyl polyglyceryl- 3 Diisostearate (Isolan® PDI), Polyglyceryl-3 Methylglucose Distearate (Tego Care® 450), Polyglyceryl-3 Beeswax (Cera Bellina®), Polyglyceryl-4 Caprate (Polyglycerol Caprate T2010/90), Polyglyceryl-3 Cetyl Ether (Chimexane® NL), polyglyceryl-3 distearate (Cremophor® GS 32) and polyglyceryl polyricinoleate (Admul® WOL 1403) polyglyceryl dimerate isostearate and mixtures thereof. Examples of other suitable polyol esters are the mono-, di- and triesters of trimethylolpropane or pentaerythritol with lauric acid, coconut fatty acid, tallow fatty acid, palmitic acid, stearic acid, oleic acid, behenic acid and the like, optionally reacted with 1 to 30 moles of ethylene oxide.
[0030] Anionische Emulgatoren. Typische anionische Emulgatoren sind aliphatische Fett säuren mit 12 bis 22 Kohlenstoffatomen, wie beispielsweise Palmitinsäure, Stearinsäure oder Behensäure, sowie Dicarbonsäuren mit 12 bis 22 Kohlenstoffatomen, wie beispielsweise Azel ainsäure oder Sebacinsäure. Anionic emulsifiers. Typical anionic emulsifiers are aliphatic fatty acids having 12 to 22 carbon atoms, such as palmitic acid, stearic acid or behenic acid, and dicarboxylic acids having 12 to 22 carbon atoms, such as azelaic acid or sebacic acid.
[0031] Amphotere und kationische Emulgatoren. Weiterhin können als Emulgatoren zwitterionische Tenside verwendet werden. Als zwitterionische Tenside werden solche ober flächenaktiven Verbindungen bezeichnet, die im Molekül mindestens eine quartäre Ammo niumgruppe und mindestens eine Carboxylat- und eine Sulfonatgruppe tragen. Besonders geeignete zwitterionische Tenside sind die sogenannten Betaine wie die N-Alkyl-N,N- dimethylammoniumglycinate, beispielsweise das Kokosalkyldimethylammoniumglycinat, N- Acylaminopropyl-N,N-dimethylammoniumglycinate, beispielsweise das Kokosacyl- aminopropyldimethyl-ammoniumglycinat, und 2-Alkyl-3-carboxylmethyl-3-hydroxyethylimi- dazoline mit jeweils 8 bis 18 C-Atomen in der Alkyl- oder Acylgruppe sowie das Kokosacyl- aminoethylhydroxyethylcarboxymethylglycinat. Besonders bevorzugt ist das unter der CTFA- Bezeichnung Cocamidopropyl Betaine bekannte Fettsäureamid-Derivat. Ebenfalls geeignete Emulgatoren sind ampholytische Tenside. Unter ampholytischen Tensiden werden solche oberflächenaktiven Verbindungen verstanden, die außer einer Cs/is-Alkyl- oder Acylgruppe im Molekül mindestens eine freie Aminogruppe und mindestens eine -COOH- oder -SO3H- Gruppe enthalten und zur Ausbildung innerer Salze befähigt sind. Beispiele für geeignete ampholytische Tenside sind N-Alkylglycine, N-Alkylpropionsäuren, N-Alkylaminobuttersäu- ren, N-Alkyliminodipropionsäuren, N-Hydroxyethyl-N-alkylamidopropylglycine, N- Alkyltaurine, N-Alkylsarcosine, 2-Alkylaminopropionsäuren und Alkylaminoessigsäuren mit jeweils etwa 8 bis 18 C-Atomen in der Alkylgruppe.. Besonders bevorzugte ampholytische Tenside sind das N-Kokosalkylaminopropionat, das Kokosacylaminoethylaminopropionat und das Ci2/i8-Acylsarcosin. Schließlich kommen auch Kationtenside als Emulgatoren in Be tracht, wobei solche vom Typ der Esterquats, vorzugsweise methylquaternierte Difettsäuret- riethanolaminester-Salze, besonders bevorzugt sind. Verdickungsmittel Amphoteric and cationic emulsifiers. Furthermore, zwitterionic surfactants can be used as emulsifiers. Zwitterionic surfactants are those surface-active compounds which contain at least one quaternary ammonium group and at least one carboxylate and one sulfonate group in the molecule. Particularly suitable zwitterionic surfactants are the so-called betaines, such as the N-alkyl-N,N-dimethylammonium glycinates, for example coconut alkyldimethylammonium glycinate, N-acylaminopropyl-N,N-dimethylammonium glycinates, for example cocoacylaminopropyldimethylammonium glycinate, and 2-alkyl-3-carboxylmethyl -3-Hydroxyethylimidazoline each having 8 to 18 carbon atoms in the alkyl or acyl group and the cocoacylaminoethylhydroxyethylcarboxymethylglycinate. The fatty acid amide derivative known under the CTFA name Cocamidopropyl Betaine is particularly preferred. Also suitable emulsifiers are ampholytic surfactants. Ampholytic surfactants are surface-active compounds which contain at least one free amino group and at least one --COOH or --SO.sub.3 H group in addition to a C.sub.s /i.s.-alkyl or acyl group in the molecule and are capable of forming inner salts. Examples of suitable ampholytic surfactants are N-alkylglycines, N-alkylpropionic acids, N-alkylaminobutyric acids, N-alkyliminodipropionic acids, N-hydroxyethyl-N-alkylamidopropylglycines, N-alkyltaurines, N-alkylsarcosines, 2-alkylaminopropionic acids and alkylaminoacetic acids, each with about 8 to 18 carbon atoms in the alkyl group.. Particularly preferred ampholytic surfactants are N-cocoalkylaminopropionate, cocoacylaminoethylaminopropionate and Ci 2/18 -acylsarcosine. Finally, cationic surfactants are also suitable as emulsifiers, with those of the esterquat type, preferably methyl-quaternized difatty acid triethanolamine ester salts, being particularly preferred. thickener
[0001] Die Verdickungsmittel, die den optionalen Bestandteil (f) darstellen, können ausge wählt sein aus der Gruppe, die gebildet wird von Aerosil-Typen (hydrophile Kieselsäuren), Polysaccharide, insbesondere Xanthan-Gum, Guar-Guar, Agar-Agar, Alginate und Tylosen, Carboxymethylcellulose und Hydroxyethyl- und Hydroxypropylcellulose, ferner hö hermolekulare Polyethylenglycolmono- und -diester von Fettsäuren, Polyacrylate, (z.B. Car bopole® und Pemulen-Typen von Goodrich; Synthalene® von Sigma; Keltrol-Typen von Kelco; Sepigel-Typen von Seppic; Salcare-Typen von Allied Colloids), Polyacrylamide, Poly mere, Polyvinylalkohol und Polyvinylpyrrolidon. Als besonders wirkungsvoll haben sich auch Bentonite, wie z.B. Bentone® Gel VS-5PC (Rheox) erwiesen, bei dem es sich um eine Mi schung aus Cyclopentasiloxan, Disteardimonium Hectorit und Propylencarbonat handelt. Weiter in Frage kommen Tenside, wie beispielsweise ethoxylierte Fettsäureglyceride, Ester von Fettsäuren mit Polyolen wie beispielsweise Pentaerythrit oder Trimethylolpropan, Fett- alkoholethoxylate mit eingeengter Homologenverteilung oder Alkyloligoglucoside sowie Elektrolyte wie Kochsalz und Ammoniumchlorid. The thickeners that represent the optional component (f) can be selected from the group formed by Aerosil types (hydrophilic silicic acids), polysaccharides, in particular xanthan gum, guar guar, agar-agar, Alginates and tyloses, carboxymethyl cellulose and hydroxyethyl and hydroxypropyl cellulose, also high molecular weight polyethylene glycol mono- and diesters of fatty acids, polyacrylates (e.g. Carbopole® and Pemulen types from Goodrich; Synthalene® from Sigma; Keltrol types from Kelco; Sepigel types from Seppic; Salcare grades from Allied Colloids), polyacrylamides, polymers, polyvinyl alcohol and polyvinylpyrrolidone. Bentonites, such as Bentone® Gel VS-5PC (Rheox), which is a mixture of cyclopentasiloxane, disteardimonium hectorite and propylene carbonate, have also proven particularly effective. Surfactants such as ethoxylated fatty acid glycerides, esters of fatty acids with polyols such as pentaerythritol or trimethylolpropane, fatty alcohol ethoxylates with a narrow homolog distribution or alkyl oligoglucosides and electrolytes such as sodium chloride and ammonium chloride are also suitable.
Emulsionen emulsions
[0032] Bei den Emulsionen, wie sie vorstehend beschrieben worden sind, handelt es sich vor zugsweise um eine Pickering-Emulsion. Hierunter versteht man ein System, das durch feste Partikel (hier: mikrokristalline Fasern) stabilisiert wird, die an der Grenzfläche zwischen den beiden Phasen adsorbieren. Diese Art von Emulsion wurde nach S.U. Pickering benannt, der das Phänomen 1907 beschrieb. Wenn Öl und Wasser gemischt werden und sich kleine Öltröpfchen bilden, die sich im Wasser verteilen, verschmelzen die Tröpfchen schließlich und verringern die Energiemenge im System. Werden dem Gemisch jedoch Feststoffpartikel zu gesetzt, binden diese an der Oberfläche der Grenzfläche und verhindern das Zusammenflie ßen der Tröpfchen, wodurch die Emulsion stabiler wird. The emulsions as described above are preferably Pickering emulsions. This is a system that is stabilized by solid particles (here: microcrystalline fibers) that adsorb at the interface between the two phases. This type of emulsion was made according to S.U. Pickering, who described the phenomenon in 1907. When oil and water mix and small oil droplets form and disperse throughout the water, the droplets eventually coalesce and reduce the amount of energy in the system. However, if solid particles are added to the mixture, they bind to the surface of the interface and prevent the droplets from coalescing, making the emulsion more stable.
[0033] Vorzugsweise setzt man Emulsionen ein, die Emulsions are preferably used which
(a) etwa 0,5 bis etwa 5 Gew.-%, vorzugsweise etwa 1 bis etwa 2,5 Gew.-% mikrokristalline Fasern, (a) from about 0.5% to about 5%, preferably from about 1% to about 2.5%, by weight of microcrystalline fibers,
(b) etwa 0,5 bis etwa 5 Gew.-%, vorzugsweise etwa 1 bis etwa 2,5 Gew.-% Wirkstoffe,(b) about 0.5 to about 5% by weight, preferably about 1 to about 2.5% by weight of active ingredients,
(c) etwa 1 bis etwa 5 Gew.-%, vorzugsweise etwa 1,5 bis etwa 2,5 Gew.-% Farbstoffe,(c) from about 1% to about 5%, preferably from about 1.5% to about 2.5%, by weight of dyes,
(d) etwa 0,5 bis etwa 5 Gew.-%, vorzugsweise etwa 1 bis etwa 2 Gew.-% Gelbildner; (d) from about 0.5% to about 5%, preferably from about 1% to about 2% by weight, of gelling agent;
(e) 0 bis etwa 5 Gew.-%, vorzugsweise etwa 0,5 bis etwa 2 Gew.-% Emulgatoren und(e) from 0% to about 5%, preferably from about 0.5% to about 2% by weight, of emulsifiers and
(f) 0 bis etwa 1 Gew.-%, vorzugsweise etwa 0,1 bis etwa 0,5 Gew.-% Verdickungsmittel mit der Maßgabe enthalten, dass sich alle Mengenangaben mit Wasser und gegebenenfalls weiteren Lösungsmitteln, insbesondere Glycerin und/oder Alkelenglykolen, zu 100 Gew.-% ergänzen. Der guten Ordnung halber sei darauf hingewiesen werden, dass sich alle mathe matisch denkbaren Kombinationen der Einsatzstoffe, die weniger oder mehr als 100 Gew.-% ergeben, nicht Gegenstand der Erfindung sind. Mit der vorliegenden technischen Lehre ist es dem Fachmann jederzeit möglich, Emulsionen zubereiten, bei denen sich die Bestandteile zu 100 Gew.-% ergänzen, ohne dazu erfinderisch tätig zu werden. (f) 0% to about 1% by weight, preferably about 0.1% to about 0.5% by weight, of thickener with the proviso that all stated quantities are compatible with water and, if appropriate, other solvents, in particular glycerol and/or alkene glycols, to 100% by weight add to. For the sake of clarity, it should be pointed out that all mathematically conceivable combinations of the starting materials that result in less than or more than 100% by weight are not the subject of the invention. With the present technical teaching, it is possible for the person skilled in the art at any time to prepare emulsions in which the components add up to 100% by weight, without being inventive.
Koazervation durch Vertropfung Coacervation by dripping
[0034] Die Emulsionen bilden die Matrix, welche noch ausgehärtet werden muss. Dies ge schieht vorzugsweise durch Koazervation, insbesondere durch Vertropfung in ein Härtungs oder Fällungsbad, beispielsweise indem man der Emulsion mit Hilfe einer oszillierenden Membran eine Schwingung aufprägt und dann durch mindestens eine Düse vertropft, wie dies beispielsweise in der EP 1413238 Al (COGNIS) beschrieben wird. Entsprechende Appara turen sind beispielsweise von der Firma Rieter Automatic GmbH erhältlich. The emulsions form the matrix, which still has to be cured. This is preferably done by coacervation, in particular by dripping in a hardening or precipitation bath, for example by imparting vibration to the emulsion with the aid of an oscillating membrane and then dripping through at least one nozzle, as described for example in EP 1413238 A1 (COGNIS). . Corresponding apparatuses are available, for example, from Rieter Automatic GmbH.
[0035] Vorzugsweise werden als Gelbildner Alginsäure oder Chitosan oder deren Salze ein setzt. Im Fall der polyanionischen Verbindungen als Gelbildner enthält das Härtungs- oder Fällbad eine kationische Verbindung, beispielsweise Calciumionen. Wird ein kationischer Gel bildner wie Chitosan eingesetzt, muss das Bad eine anionische Verbindung, beispielsweise Alginat enthalten. [0035] Preferably, alginic acid or chitosan or their salts are used as gel formers. In the case of polyanionic compounds as gelling agents, the hardening or precipitation bath contains a cationic compound, for example calcium ions. If a cationic gelling agent such as chitosan is used, the bath must contain an anionic compound such as alginate.
[0036] Nach Koazervation, Filtration und gegebenenfalls Trocknung erhält man Mikrokapseln mit einem mittleren Durchmesser von vorzugsweise 1 bis 3 mm. Es ist ratsam, die Kapseln zu sieben, um eine gleichmäßige Größenverteilung zu gewährleisten. Die so erhaltenen Mikro kapseln können innerhalb der produktionsbedingten Grenzen jede beliebige Form haben, sind aber vorzugsweise im Wesentlichen kugelförmig. After coacervation, filtration and optional drying, microcapsules with an average diameter of preferably 1 to 3 mm are obtained. It is advisable to sieve the capsules to ensure an even size distribution. The microcapsules thus obtained can have any shape within the production-related limits, but are preferably essentially spherical.
DETERGENSZUBEREITUNGEN DETERGENT PREPARATIONS
[0037] Die vorliegende Erfindung umfasst ferner Detergenszubereitungen, die die erfin dungsgemäßen Wirkstoffkapseln enthalten. Bei diesen Zubereitungen handelt es sich bei spielsweise um Seifenbasen, Stückseifen, Syndetseifen, Flüssigseifen, Cremeseifen und der gleichen, die für die Körperreinigung vorgesehen sind. Die genannten Produkttypen, denen die Kapseln zugesetzt werden sollen, werden zusammenfassend als Detergensbasis bezeich net. Die Detergensbasis kann die erfindungsgemäßen Kapseln in Mengen von etwa 0,5 bis etwa 5 Gew.-%, vorzugsweise etwa 1 bis etwa 2 Gew.-% enthalten. The present invention also encompasses detergent preparations which contain the active ingredient capsules according to the invention. These preparations are, for example, soap bases, bar soaps, syndet soaps, liquid soaps, cream soaps and the like intended for body cleansing. The product types mentioned to which the capsules are to be added are collectively referred to as detergent bases. The detergent base may contain the capsules of the invention in amounts of from about 0.5% to about 5% by weight, preferably from about 1% to about 2% by weight.
[0038] Im Wesentlichen besteht die Detergensbasis aus einem Tensid oder einer Tensidmi schung, wobei diese sich wiederum vorzugsweise aus anionischen sowie Mischungen von anionischen und amphoteren Tensiden zusammensetzt. Weiterhin kann die Detergensbasis pflanzliche Öle sowie die Komponenten enthalten, die auch Bestandteil der vorstehend ge- nannten Emulsionen sein, also vor allem Emulgatoren, Verdickungsmittel, Parfüm- und Farb stoffe. The detergent base essentially consists of a surfactant or a surfactant mixture, which in turn is preferably composed of anionic and mixtures of anionic and amphoteric surfactants. Furthermore, the detergent base can contain vegetable oils and the components that are also part of the above be called emulsions, so mainly emulsifiers, thickeners, perfumes and dyes.
Anionische und amphotere Tenside Anionic and amphoteric surfactants
[0039] Typische Beispiele für anionische und amphotere (auch zwitterionische genannt) Tenside, die die Komponente (a) bilden, umfassen: Mandelamidopropylaminoxid, Man- delamidopropylbetain, Aminopropyllaurylglutamin, Ammonium C12-15 Alkylsulfat, Ammo nium C12-16 Alkylsulfat, Ammonium Caprylethsulfat, Ammonium Cocomonoglyceridsulfat, Ammonium Coco-Sulfat, Ammonium Cocoyl Isethionate, Ammonium Cocoyl Sarcosinate, Ammonium C12-15 Pareth Sulfate, Ammonium C9-10 Perfluoroalkylsulfonate, Ammonium Dinonyl Sulfosuccinate, Ammonium Dodecylbenzolsulfonat, Ammonium Isostearat, Ammo nium Laureth-6 Carboxylat, Ammonium Laureth-8 Carboxylat, Ammonium Laureth Sulfat, Ammonium Laureth-5 Sulfat, Ammonium Laureth-7 Sulfat, Ammonium Laureth-9 Sulfat, Ammonium Laureth-12 Sulfat, Ammonium Lauroyl Sarcosinate, Ammonium Lauryl Sulfate, Ammonium Lauryl Sulfosuccinate, Ammonium Myreth Sulfate, Ammonium Myristyl Sulfate, Ammonium Nonoxynol-4 Sulfate, Ammonium Nonoxynol-S0 Sulfate, Ammonium Oleate, Ammonium Palm Kernel Sulfate, Ammonium Stearate, Ammonium Tallate, AMPD- Isostearoyl Hydrolyzed Collagen, AMPD-Rosin Hydrolyzed Collagen, AMP-Isostearoyl Hydro- lyzed Collagen, AMP-Isostearoyl Hydrolyzed Keratin, AMP-Isostearoyl Hydrolyzed Soy Pro tein, AMP-Isostearoyl Hydrolyzed Wheat Protein, Apricotamidopropyl Betaine, Arachidic Acid, Arginine Hexyldecyl Phosphate, Avocadamidopropyl Betaine, Avocado Oil Glycereth-8 Esters, Babassu Acid, Babassuamidopropylamine Oxide, Babassuamidopropyl Betaine, Beeswax Acid, Behenamidopropyl Betaine, Behenamine Oxide, Beheneth-25, Beheneth-30, Behensäure, Behenyl Betain, Bis- Butyldimethicone Polyglyceryl-3, Butoxynol-5 Carboxylic Acid, Butoxynol-19 Carboxylic Acid, Butyldimoniumhydroxypropyl Butylglucosides Chloride, Butyldimoniumhydroxypropyl Laurylglucosides Chloride, Butyl Glucoside, Butylglucoside Caprate, Butylglucosides Hydroxypropyltrimonium Chloride, Butyloctanoic Acid, C18-36 A- cid, C20-40 Acid, C30-50 Acid, C16-22-Säureamid MEA, Calciumdodecylbenzolsulfonat, Cal cium la uroylta u rat, C9-16-Alkan/Cycloalkan, C10-14-Alkylbenzolsulfonsäure, C12-14- Alkyldiaminoethylglycin HCL, C9-15-Alkylphosphat, Candida Bombicola/Glucose/Methyl- Rapsöl-Ferment, Canolamidopropylbetain, Caprinsäure, Capronsäure, Caproylethylglucosid, Capryl/Capramidopropylbetain, Capryleth-4 Carboxylsäure, Capryleth-6-Carbonsäure, Capryleth-9-Carbonsäure, Caprylsäure, Capryloyl-Kollagen-Aminosäuren, Capryloyl-Glycin, Capryloyl-hydrolysiertes Kollagen, Capryloyl-hydrolysiertes Keratin, Capryloyl-Keratin- Aminosäuren, Capryloyl Silk Amino Acids, Caprylyl/Capryl Glucoside, Caprylyl/Capryl Wheat Bran/Straw Glycosides, Caprylyl Glucoside, Caprylyl Glyceryl Ether, Caprylyl Pyrrolidone, Carnitine, Ceteareth-20, Ceteareth-23, Ceteareth-24, Ceteareth-25, Ceteareth-27, Cetea- reth-28, Ceteareth-29, Ceteareth-30, Ceteareth-33, Ceteareth-34, Ceteareth-40, Ceteareth- 50, Ceteareth-55, Ceteareth-60, Ceteareth-80, Ceteareth-100, Ceteareth-25 Carbonsäure, Ceteareth-2 Phosphat, Ceteareth-4 Phosphat, Ceteareth-5 Phosphat, Ceteareth-10 Phos- phat, Ceteth-20, Ceteth-23, Ceteth-24, Ceteth-25, Ceteth-30, Ceteth-40, Ceteth-45, Ceteth- 150, Ceteth-8-Phosphat, Ceteth-10-Phosphat, Ceteth-20-Phosphat, Cetoleth-22, Cetoleth- 24, Cetoleth-25, Cetoleth-30, Cetylbetain, Chrysanthemum Sinense Flower Extract, C12-14 Hydroxyalkyl Hydroxyethyl Beta-Alanine, C12-14 Hydroxyalkyl Hydroxyethyl Sarcosine, Co- camidoethyl Betaine, Cocamidopropylamine Oxide, Cocamidopropyl Betainamide MEA Chlo ride, Cocamidopropyl Betaine, Cocamidopropyl Hydroxysultaine, Cocamine Oxide, Cocami- nobutyric Acid, Cocaminopropionic Acid, Coceth-7 Carboxylic Acid, Coceth-4 Glucoside, Cocoamphodipropionic Acid, Cocobetainamido Amphopropionate, Coco-Betaine, Cocodi- monium Hydroxypropyl Hydrolyzed Rice Protein, Cocodimonium Hydroxypropyl Hydrolyzed Soy Protein, Cocodimonium Hydroxypropyl Hydrolyzed Wheat Protein, Coco-Glucoside, Cocoglucosides Hydroxypropyltrimonium Chloride, Coco- Hydroxysultaine, Coco-Morpholine Oxide, Coconut Acid, Coconut Oil Glycereth-8 Esters, Coco/Oleamidopropyl Betaine, Coco- Sultaine, Coco/Sunfloweramidopropyl Betaine, Cocoylcholine Methosulfate, Cocoyl Gluta- mic Acid, Cocoyl Hydrolyzed Collagen, Cocoyl Hydrolyzed Keratin, Cocoyl Hydrolyzed Oat Protein, Cocoyl Hydrolyzed Rice Protein, Cocoyl Hydrolyzed Silk, Cocoyl Hydrolyzed Soy Pro tein, Cocoyl Hydrolyzed Wheat Protein, Cocoyl Sarcosine, Com Acid, Cottonseed Acid, Cot- tonseed Oil Glycereth-8 Esters, C10-16 Pareth-1, C10-16 Pareth-2, Cll-13 Pareth-6, Cll-13 Pareth-9, Cll-13 Pareth-10, Cll-15 Pareth-30, Cll-15 Pareth-40, C12-13 Pareth-1, C12-13 Pareth- 23, C12-14 Pareth-5, C12-14 Pareth-9, C13-15 Pareth-21, C14-15 Pareth-8, C20-22 Pareth-30, C20- 40 Pareth-40, C20-40 Pareth-95, C22-24 Pareth-33, C30-50 Pareth-40, C9-11 Pareth-6 Carboxylic Acid, C9-11 Pareth-8 Carboxylic Acid, Cll-15 Pareth-7 Carboxylic Acid, C12-13 Pareth-5 Carboxylic Acid, C12-13 Pareth-7 Carboxylic Acid, C12-13 Pareth-8 Carboxy lic Acid, C12-13 Pareth-12 Carboxylic Acid, C12-15 Pareth-7 Carboxylic Acid, C12-15 Pareth-8 Carboxylic Acid, C12-15 Pareth- 12 Carboxylic Acid, C14-15 Pareth-8 Carboxylic Acid, C6-10 Pareth-4 Phosphate, C12-13 Pareth-2 Phosphate, C12-13 Pareth-10 Phosphate, C12-15 Pa- reth-6 Phosphate, C12-15 Pareth-8 Phosphate, C12-15 Pareth-10 Phosphate, C12-16 Pareth- 6 Phosphate, C4-18 Perfluoroalkylethyl Thiohydroxypropyltrimonium Chloride, Cupuassu- amidopropyl Betaine, DEA-C12-13 Alkyl Sulfate, DEA-C12-15 Alkyl Sulfate, DEA-Ceteareth-2 Phosphate, DEA-Cetyl Sulfate, DEA- Cocoamphodipropionate, DEA-C12-13 Pareth-3 Sulfate, DEA-Cyclocarboxypropyloleate, DEA- Dodecylbenzenesulfonate, DEA-Isostearate, DEA- Laureth Sulfate, DEA-Lauryl Sulfate, DEA- Linoleate, DEA-Methyl Myristate Sulfonate, DEA- Myreth Sulfate, DEA-Myristate, DEA-Myristyl Sulfate, DEA-Oleth-5 Phosphate, DEA-Oleth-20 Phosphate, DEA PG-Oleate, Deceth-7 Carboxylic Acid, Deceth-7 Glucoside, Deceth-9 Phos phate, Decylamine Oxide, Decyl Betaine, Decyl Glucoside, Decyltetradeceth-30, Decyltetra- decylamine Oxide, Diammonium Lauramido-MEA Sulfosuccinate, Diammonium Lauryl Sulfo- succinate, Diammonium Oleamido PEG-2 Sulfosuccinate, Dibutoxymethane, Di-Cl 2-15 Pa- reth-2 Phosphate, Di-Cl 2-15 Pareth-4 Phosphate, Di-Cl 2-15 Pareth-6 Phosphate, Di- C12-15 Pareth-8 Phosphate, Di-Cl 2-15 Pareth-10 Phosphate, Didodecyl Butanetetracarboxylate, Diethylamine Laureth Sulfate, Diethylhexyl Sodium Sulfosuccinate, Dihydroxyethyl C8-10 Alkoxypropylamine Oxide, Dihydroxyethyl C9-11 Alkoxypropylamine Oxide, Dihydroxyethyl C12-15 Alkoxypropylamine Oxide, Dihydroxyethyl Cocamine Oxide, Dihydroxyethyl Laurami- ne Oxide, Dihydroxyethyl Stearamine Oxide, Dihydroxyethyl Tallowamine Oxide, Dimethico- ne PEG-7 Phosphate, Dimethicone PEG-10 Phosphate, Dimethicone PEG/PPG-7/4 Phospha te, Dimethicone PEG/PPG-12/4-Phosphat, Dimethicone/Polyglycerin-B-Crosspolymer, Dime thicone Propyl PG- Betaine, Dimyristyl Phosphate, Dioleoylamidoethyl Hydroxyethylmonium Methosulfate, DIPA- Hydrogenated Cocoate, DIPA-Lanolat, DIPA-Myristat, Dipotassium Capryloyl Glutamate, Dipotassium Lauryl Sulfosuccinate, Dipotassium Undecylenoyl Gluta mate, Disodium Babassuamido MEA-Sulfosuccinate, Disodium Caproamphodiacetate, Dinat- rium-Caproamphodipropionat, Dinatrium-Capryloamphodiacetat, Dinatrium-Typical examples of anionic and amphoteric (also called zwitterionic) surfactants forming component (a) include: mandelamidopropylamine oxide, mandelamidopropylbetaine, aminopropyllaurylglutamine, ammonium C12-15 alkyl sulfate, ammonium C12-16 alkyl sulfate, ammonium capryth sulfate, Ammonium Cocomonoglyceride Sulfate, Ammonium Coco Sulfate, Ammonium Cocoyl Isethionate, Ammonium Cocoyl Sarcosinate, Ammonium C12-15 Pareth Sulfate, Ammonium C9-10 Perfluoroalkylsulfonates, Ammonium Dinonyl Sulfosuccinate, Ammonium Dodecylbenzenesulfonate, Ammonium Isostearate, Ammonium Laureth-6 Carboxylate, Ammonium Laureth-8 Carboxylate, Ammonium Laureth Sulfate, Ammonium Laureth-5 Sulfate, Ammonium Laureth-7 Sulfate, Ammonium Laureth-9 Sulfate, Ammonium Laureth-12 Sulfate, Ammonium Lauroyl Sarcosinate, Ammonium Lauryl Sulfate, Ammonium Lauryl Sulfosuccinate, Ammonium Myreth Sulfate, Ammonium Myristyl Sulfate, Ammonium Nonoxynol-4 Sulfate, Ammonium Nonoxynol-S0 Sulfate, Ammonium Oleate, Ammonium Palm Kernel Sulfate, Ammonium Stearate, Ammonium Tallate, AMPD- Isostearoyl Hydrolyzed Collagen, AMPD-Rosin Hydrolyzed Collagen, AMP-Isostearoyl Hydrolyzed Collagen, AMP-Isostearoyl Hydrolyzed Keratin, AMP-Isostearoyl Hydrolyzed Soy Protein, AMP-Isostearoyl Hydrolyzed Wheat Protein, Apricotamidopropyl Betaine, Arachidic Acid, Arginine Hexyldecyl Phosphate, Avocadamidopropyl Betaine, Avocado Oil Glycereth-8 Esters, Babassu Acid, Babassuamidopropylamine Oxide, Babassuamidopropyl Betaine, Beeswax Acid, Behenamidopropyl Betaine, Behenamine Oxide, Beheneth-25, Beheneth-30, Behenic Acid, Behenyl Betaine , Bis- Butyldimethicone Polyglyceryl-3, Butoxynol-5 Carboxylic Acid, Butoxynol-19 Carboxylic Acid, Butyldimoniumhydroxypropyl Butylglucosides Chloride, Butyldimoniumhydroxypropyl Laurylglucosides Chloride, Butyl Glucoside, Butylglucoside Caprate, Butylglucosides Hydroxypropyltrimonium Chloride, Butyloctanoic Acid, C18-36 A- cid, C20- 40 Acid, C30-50 Acid, C16-22 Acid Amide MEA, Calcium Dodecylbenzene sulfonate, calcium la uroyl taurate, C9-16 alkane/cycloalkane, C10-14 alkyl benzene sulfonic acid, C12-14 alkyl diaminoethyl glycine HCL, C9-15 alkyl phosphate, candida bombicola/glucose/methyl rapeseed ferment, canolamidopropyl betaine, capric acid , Capronic Acid, Caproyl Ethyl Glucoside, Capryle/Capramidopropyl Betaine, Capryleth-4 Carboxylic Acid, Capryleth-6 Carboxylic Acid, Capryleth-9 Carboxylic Acid, Caprylic Acid, Capryloyl Collagen Amino Acids, Capryloyl Glycine, Capryloyl Hydrolyzed Collagen, Capryloyl Hydrolyzed Keratin, Capryloyl Keratin Amino Acids, Capryloyl Silk Amino Acids, Caprylyl/Caprylic Glucoside, Caprylyl/Caprylic Wheat Bran/Straw Glycosides, Caprylyl Glucoside, Caprylyl Glyceryl Ether, Caprylyl Pyrrolidone, Carnitine, Ceteareth-20, Ceteareth-23, Ceteareth-24, Ceteareth-25 , ceteareth-27, ceteareth-28, ceteareth-29, ceteareth-30, ceteareth-33, ceteareth-34, ceteareth-40, ceteareth-50, ceteareth-55, ceteareth-60, ceteareth-80, ceteareth-100 , ceteareth-25 carboxylic acid, ceteareth-2 phosphate, cete areth-4 phosphate, ceteareth-5 phosphate, ceteareth-10 phos- phat, ceteth-20, ceteth-23, ceteth-24, ceteth-25, ceteth-30, ceteth-40, ceteth-45, ceteth- 150, ceteth-8-phosphate, ceteth-10-phosphate, ceteth-20- Phosphate, Cetoleth-22, Cetoleth- 24, Cetoleth-25, Cetoleth-30, Cetyl Betaine, Chrysanthemum Sinense Flower Extract, C12-14 Hydroxyalkyl Hydroxyethyl Beta-Alanine, C12-14 Hydroxyalkyl Hydroxyethyl Sarcosine, Co- camidoethyl Betaine, Cocamidopropylamine Oxide, Cocamidopropyl Betainamide MEA Chloride, Cocamidopropyl Betaine, Cocamidopropyl Hydroxysultaine, Cocamine Oxide, Cocaminobutyric Acid, Cocaminopropionic Acid, Coceth-7 Carboxylic Acid, Coceth-4 Glucoside, Cocoamphodipropionic Acid, Cocobetainamido Amphopropionate, Coco-Betaine, Cocodimonium Hydroxypropyl Hydrolyzed Rice Protein , Cocodimonium Hydroxypropyl Hydrolyzed Soy Protein, Cocodimonium Hydroxypropyl Hydrolyzed Wheat Protein, Coco-Glucoside, Cocoglucosides Hydroxypropyltrimonium Chloride, Coco- Hydroxysultaine, Coco-Morpholine Oxide, Coconut Acid, Coconut Oil Glycereth-8 Esters, Co co/Oleamidopropyl Betaine, Coco- Sultaine, Coco/Sunfloweramidopropyl Betaine, Cocoylcholine Methosulfate, Cocoyl Glutamic Acid, Cocoyl Hydrolyzed Collagen, Cocoyl Hydrolyzed Keratin, Cocoyl Hydrolyzed Oat Protein, Cocoyl Hydrolyzed Rice Protein, Cocoyl Hydrolyzed Silk, Cocoyl Hydrolyzed Soy Protein , Cocoyl Hydrolyzed Wheat Protein, Cocoyl Sarcosine, Com Acid, Cottonseed Acid, Cottonseed Oil Glycereth-8 Esters, C10-16 Pareth-1, C10-16 Pareth-2, Cll-13 Pareth-6, Cll-13 Pareth- 9, Cll-13 Pareth-10, Cll-15 Pareth-30, Cll-15 Pareth-40, C12-13 Pareth-1, C12-13 Pareth-23, C12-14 Pareth-5, C12-14 Pareth-9 , C13-15 Pareth-21, C14-15 Pareth-8, C20-22 Pareth-30, C20-40 Pareth-40, C20-40 Pareth-95, C22-24 Pareth-33, C30-50 Pareth-40, C9-11 Pareth-6 Carboxylic Acid, C9-11 Pareth-8 Carboxylic Acid, Cll-15 Pareth-7 Carboxylic Acid, C12-13 Pareth-5 Carboxylic Acid, C12-13 Pareth-7 Carboxylic Acid, C12-13 Pareth- 8 Carboxylic Acid, C12-13 Pareth-12 Carboxylic Acid, C12-15 Pareth-7 Carboxylic Acid, C12-15 Pareth-8 Carboxylic Acid, C12-15 Pareth- 12 Carboxylic Acid, C14-15 Pareth-8 Carboxylic Acid, C6-10 Pareth-4 Phosphate, C12-13 Pareth-2 Phosphate, C12-13 Pareth-10 Phosphate , C12-15 Pareth-6 Phosphate, C12-15 Pareth-8 Phosphate, C12-15 Pareth-10 Phosphate, C12-16 Pareth- 6 Phosphate, C4-18 Perfluoroalkylethyl Thiohydroxypropyltrimonium Chloride, Cupuassu- amidopropyl Betaine, DEA-C12 -13 Alkyl Sulfate, DEA-C12-15 Alkyl Sulfate, DEA-Ceteareth-2 Phosphate, DEA-Cetyl Sulfate, DEA- Cocoamphodipropionate, DEA-C12-13 Pareth-3 Sulfate, DEA-Cyclocarboxypropyloleate, DEA- Dodecylbenzenesulfonate, DEA-Isostearate , DEA- Laureth Sulfate, DEA-Lauryl Sulfate, DEA- Linoleate, DEA-Methyl Myristate Sulfonate, DEA- Myreth Sulfate, DEA-Myristate, DEA-Myristyl Sulfate, DEA-Oleth-5 Phosphate, DEA-Oleth-20 Phosphate, DEA PG-Oleate, Deceth-7 Carboxylic Acid, Deceth-7 Glucoside, Deceth-9 Phosphate, Decylamine Oxide, Decyl Betaine, Decyl Glucoside, Decyltetradeceth-30, Decyltetradecylamine Oxide, D iammonium Lauramido-MEA Sulfosuccinate, Diammonium Lauryl Sulfo- succinate, Diammonium Oleamido PEG-2 Sulfosuccinate, Dibutoxymethane, Di-Cl 2-15 Pareth-2 Phosphate, Di-Cl 2-15 Pareth-4 Phosphate, Di-Cl 2- 15 Pareth-6 Phosphate, Di- C12-15 Pareth-8 Phosphate, Di-Cl 2-15 Pareth-10 Phosphate, Didodecyl Butanetetracarboxylate, Diethylamine Laureth Sulfate, Diethylhexyl Sodium Sulfosuccinate, Dihydroxyethyl C8-10 Alkoxypropylamine Oxide, Dihydroxyethyl C9-11 Alkoxypropylamine Oxide, Dihydroxyethyl C12-15 Alkoxypropylamine Oxide, Dihydroxyethyl Cocamine Oxide, Dihydroxyethyl Laurami- Ne Oxide, Dihydroxyethyl Stearamine Oxide, Dihydroxyethyl Tallowamine Oxide, Dimethicone PEG-7 Phosphate, Dimethicone PEG-10 Phosphate, Dimethicone PEG/PPG-7/4 Phospha te, Dimethicone PEG/PPG-12/4-Phosphate, Dimethicone/Polyglycerin -B-Crosspolymer, Dimethicone Propyl PG- Betaine, Dimyristyl Phosphate, Dioleoylamidoethyl Hydroxyethylmonium Methosulfate, DIPA- Hydrogenated Cocoate, DIPA Lanolat, DIPA Myristat, Dipotassium Capryloyl Glutamate, Dipotassium Lauryl Sulfosuccinate, Dipotassium Undecylenoyl Glutamate, Disodium Babassuamido MEA-Sulfosuccinate , disodium caproamphodiacetate, disodium caproamphodipropionate, disodium capryloamphodiacetate, disodium
Capryloamphodipropionat, Dinatrium-Capryloylglutamat, Dinatrium-Cetearylsulfosuccinat, Dinatrium-Cetylphenyletherdisulfonat, Disodium Cetyl Sulfosuccinate, Disodium Cocamido MEA-Sulfosuccinate, Disodium Cocamido MIPA PEG-4 Sulfosuccinate, Disodium Cocamido MIPA-Sulfosuccinate, Disodium Cocamido PEG-3 Sulfosuccinate, Disodium Coceth-3 Sulfo succinate, Disodium Cocoamphocarboxyethylhydroxypropylsulfonat, Disodium Cocoampho- diacetat, Disodium Cocoamphodipropionat, Disodium Coco-Glucosid-Sulfosuccinat, Disodi um Coco-Sulfosuccinat, Disodium Cocoyl Butyl Gluceth-10 Sulfosuccinat, Disodium Cocoyl Glutamate, Disodium C12-14 Pareth-1 Sulfosuccinate, Disodium C12-14 Pareth-2 Sulfosucci nate, Disodium C12-15 Pareth Sulfosuccinate, Disodium C12-14 Sec-Pareth-3 Sulfosuccinate, Dinatrium C12-14 Sec-Pareth-5 Sulfosuccinat, Dinatrium C12-14 Sec-Pareth-7 Sulfosuccinat, Dinatrium C12-14 Sec-Pareth-9 Sulfosuccinat, Dinatrium C12-14 Sec-Pareth-12 Sulfosuc cinat, Disodium Deceth-5 Sulfosuccinate, Disodium Deceth-6 Sulfosuccinate, Disodium Decyl Phenyl Ether Disulfonate, Disodium Dihydroxyethyl Sulfosuccinylundecylenate, Disodium Ethylene Dicocamide PEG-15 Disulfate, Disodium Hydrogenated Cottonseed Glyceride Sulfo succinate, Disodium Hydrogenated Tallow Glutamate, Disodium Hydroxydecyl Sorbitol Citra te, Disodium Isodecyl Sulfosuccinate, Disodium Isostearamido MEA-Sulfosuccinate, Disodi um Isostearamido MIPA-Sulfosuccinate, Disodium Isostearoamphodiacetate, Disodium Isostearoamphodipropionate, Disodium Isostearyl Sulfosuccinate, Disodium Laneth-5 Sulfo succinate, Disodium Lauramido MEA-Sulfosuccinate, Disodium Lauramido MIPA Glycol Sul fosuccinate, Disodium Lauramido PEG-2 Sulfosuccinate, Disodium Lauramido PEG-5 Sulfo succinate, Disodium Laureth-5 Carboxyamphodiacetate, Dinatrium-Laureth-7-Citrat, Dinat- rium-Laureth-Sulfosuccinat, Dinatrium-Laureth-6-Sulfosuccinat, Dinatrium-Laureth-9- Sulfosuccinat, Dinatrium-Laureth-12-Sulfosuccinat, Dinatrium-Capryloamphodipropionate, Disodium Capryloylglutamate, Disodium Cetearylsulfosuccinate, Disodium Cetylphenyletherdisulfonate, Disodium Cetyl Sulfosuccinate, Disodium Cocamido MEA-Sulfosuccinate, Disodium Cocamido MIPA PEG-4 Sulfosuccinate, Disodium Cocamido MIPA-Sulfosuccinate, Disodium Cocamido PEG-3 Sulfosuccinate, Disodium Coceth-3 Sulfo succinate, disodium cocoamphocarboxyethylhydroxypropylsulfonate, disodium cocoampho- diacetate, disodium cocoamphodipropionate, disodium coco-glucoside sulfosuccinate, disodium coco sulfosuccinate, disodium cocoyl butyl gluceth-10 sulfosuccinate, disodium cocoyl glutamate, disodium C12-14 pareth-1 sulfosuccinate, disodium C12- 14 Pareth-2 Sulfosuccinate, Disodium C12-15 Pareth Sulfosuccinate, Disodium C12-14 Sec-Pareth-3 Sulfosuccinate, Disodium C12-14 Sec-Pareth-5 Sulfosuccinate, Disodium C12-14 Sec-Pareth-7 Sulfosuccinate, Disodium C12- 14 Sec-Pareth-9 Sulfosuccinate, Disodium C12-14 Sec-Pareth-12 Sulfosuccinate, Disodium Deceth-5 Sulfosuccinate, Disodiu m Deceth-6 Sulfosuccinate, Disodium Decyl Phenyl Ether Disulfonate, Disodium Dihydroxyethyl Sulfosuccinylundecylenate, Disodium Ethylene Dicocamide PEG-15 Disulfate, Disodium Hydrogenated Cottonseed Glyceride Sulfo succinate, Disodium Hydrogenated Tallow Glutamate, Disodium Hydroxydecyl Sorbitol Citrate, Disodium Isodecyl Sulfosuccinate, Disodium Isostearamido MEA- Sulfosuccinate, Disodium Isostearamido MIPA-Sulfosuccinate, Disodium Isostearoamphodiacetate, Disodium Isostearoamphodipropionate, Disodium Isostearyl Sulfosuccinate, Disodium Laneth-5 Sulfo succinate, Disodium Lauramido MEA-Sulfosuccinate, Disodium Lauramido MIPA Glycol Sul fosuccinate, Disodium Lauramido PEG-2 Sulfosuccinate, Disodium Lauramido PEG- 5 sulfo succinate, disodium laureth-5 carboxyamphodiacetate, disodium laureth-7 citrate, disodium laureth sulfosuccinate, disodium laureth-6 sulfosuccinate, disodium laureth-9 sulfosuccinate, disodium laureth-12 sulfosuccinate, disodium
Lauriminobishydroxypropylsulfonat, Dinatrium-Lauriminodiacetat, Dinatrium-Lauriminobishydroxypropylsulfonate, disodium lauriminodiacetate, disodium
Lauriminodipropionat, Dinatrium-Lauriminodipropionat Tocopherylphosphate, Dinatrium- Lauroamphodiacetat, Dinatrium-Lauroamphodipropionat, Dinatrium-N- Lauroyl-Aspartat, Disodium Lauroyl Glutamate, Disodium Lauryl Phenyl Ether Disulfonate, Disodium Lauryl Sulfosuccinate, Disodium Myristamido MEA-Sulfosuccinate, Disodium Nonoxynol-10 Sulfo succinate, Disodium Oleamido MEA-Sulfosuccinate, Disodium Oleamido MIPA- Sulfosuccinate, Disodium Oleamido PEG-2 Sulfosuccinate, Disodium Oleoamphodipropiona- te, Disodium Oleth-3 Sulfosuccinate, Disodium Oleyl Phosphate, Disodium Oleyl Sulfosucci nate, Disodium Palmitamido PEG-2 Sulfosuccinate, Disodium Palmitoleamido PEG-2 Sulfo succinate, Disodium PEG-4 Cocamido MIPA-Sulfosuccinate, Disodium PEG-12 Dimethicone Sulfosuccinate, Disodium PEG-8 Palm Glycerides Sulfosuccinate, Disodium PPG-2-lsodeceth- 7 Carboxyamphodiacetate, Disodium Ricinoleamido MEA-Sulfosuccinate, Disodium Sitoste- reth-14 Sulfosuccinate, Disodium Soyamphodiacetate, Disodium Stearamido MEA- Sulfosuccinate, Disodium Steariminodipropionate, Disodium Stearoamphodiacetate, Disodi um Stearoyl Glutamate, Disodium Stearyl Sulfosuccinamate, Disodium Stearyl Sulfosuccina te, Disodium 2-Sulfolaurate, Disodium 2-Sulfopalmitate, Disodium Tallamido MEA- Sulfosuccinate, Disodium Tallowamido MEA-Sulfosuccinate, Disodium Tallowamphodiaceta- te, Disodium Tallowiminodipropionate, Disodium Tallow Sulfosuccinamate, Disodium Tride- cylsulfosuccinate, Disodium Undecylenamido MEA-Sulfosuccinate, Disodium Undecylena- mido PEG-2 Sulfosuccinate, Disodium Undecylenoyl Glutamate, Disodium Wheat Germa- mido MEA-Sulfosuccinate, Disodium Wheat Germamido PEG-2 Sulfosuccinate, Disodium Wheatgermamphodiacetate, Di-TEA-Cocamide Diacetate, Di-TEA-Oleamido PEG-2 Sulfosuc cinate, Di-TEA-Palmitoyl Aspartate, Ditridecyl Sodium Sulfosuccinate, Dodecylbenzene Sul- fonic Acid, Erucamidopropyl Hydroxysultaine, Ethylhexeth-S Carboxylic Acid, Ethyl PEG-15 Cocamine Sulfate, Glyceryl Capryl Ether, Hexyldecanoic Acid, Hydrogenated Coconut Acid, Hydrogenated Laneth-25, Hydrogenated Menhaden Acid, Hydrogenated Palm Acid, Hydro genated Palm Kernel Amine Oxide, Hydrogenated Tallow Acid, Hydrogenated Tallowamine Oxide, Hydrogenated Tallow Betaine, Hydrogenated Talloweth-25, Hydrogenated Tallowoyl Glutamic Acid, Hydrolyzed Candida Bombicola Extract, Hydroxyceteth-60, Hydroxyethyl Ace- tomonium PG-Dimethicone, Hydroxyethylbutylamine Laureth Sulfate, Hydroxyethyl Car- boxymethyl Cocamidopropylamine, Hydroxyethyl Hydroxypropyl C12-15 Alkoxypropylamine Oxide, Hydroxylauryl/Hydroxymyristyl Betaine, Hydroxystearic Acid, Hydroxysuccinimidyl C10-40 Isoalkyl Acidate, Hydroxysuccinimidyl C21-22 Isoalkyl Acidate, Hydroxysultaines, IPDI/PEG-15 Soyamine Oxide Copolymer, IPDI/PEG-15 Soyethonium Ethosulfate Copolymer, IPDI/PEG-15 Soy Glycinate Copolymer, lsoceteth-30, lsolaureth-4 Phosphate, Isopolyglyceryl- 3 Dimethicone, lsopolyglyceryl-3 Dimethiconol, Isopropanolamine Lanolate, Isopropylamine Dodecylbenzenesulfonate, Isostearamidopropylamine Oxide, Isostearamidopropyl Betaine, Isostearamidopropyl Morpholine Oxide, lsosteareth-8, lsosteareth-16, lsosteareth-22, lsosteareth-25, lsosteareth-50, Isostearic Acid, Isostearoyl Hydrolyzed Collagen, Jojoba Oil PEG-150 Esters, Jojoba Wax PEG-80 Esters, Jojoba Wax PEG-120 Esters, Laneth-20, Laneth- 25, Laneth-40, Laneth-50, Laneth-60, Laneth-75, Lanolin Acid, Lauramidopropylamine Oxide, Lauramidopropyl Betaine, Lauramidopropyl Hydroxysultaine, Lauramine Oxide, Lauraminop- ropionic Acid, Laurdimoniumhydroxypropyl Decylglucosides Chloride, Laurdimoniumhydro- xypropyl Laurylglucosides Chloride, Laureth-16, Laureth-20, Laureth-21, Laureth-23, Lau- reth-25, Laureth-30, Laureth-38, Laureth-40, Laureth-3 Carboxylic Acid, Laureth-4 Carboxylic Acid, Laureth-5 Carboxylic Acid, Laureth- 6 Carboxylic Acid, Laureth-8 Carboxylic Acid, Lau- reth-10 Carboxylic Acid, Laureth-11 Carboxylic Acid, Laureth-12 Carboxylic Acid, Laureth-13 Carboxylic Acid, Laureth-14 Carboxylic Acid, Laureth-17 Carboxylic Acid, Laureth-6 Citrate, Laureth-7 Citrate, Laureth-1 Phosphate, Laureth-2 Phosphate, Laureth-3 Phosphate, Lau- reth-4 Phosphate, Laureth-7 Phosphate, Laureth-8 Phosphat, Laureth-7-Tartrat, Laurie- Säure, Laurimino-Bispropandiol, Lauriminodipropionsäure, Lauroamphodipropionsäure, Lauroyl-Beta-Alanin, Lauroyl-Kollagen-Aminosäuren, Lauroyl-Ethyltrimonium-Methosulfat, Lauroyl Hydrolyzed Collagen, Lauroyl Hydrolyzed Elastin, Lauroyl Methyl Glucamide, Lauroyl Sarcosine, Lauroyl Silk Amino Acids, Lauryl Betaine, Lauryl Dimethicone/Polyglycerin-3 Crosspolymer, Lauryldimoniumhydroxypropyl Cocoglucosides Chloride, Lauryl Glucoside, Laurylglucosides Hydroxypropyltrimonium Chloride, Lauryl Glycol Hydroxypropyl Ether, Lau ryl Hydroxysultaine, Lauryl Malamide, Lauryl Methylglucamide, Lauryl/Myristyl Glycol Hyd roxypropyl Ether, Lauryl/Myristyl Wheat Bran/Straw Glycosides, Lauryl Polyglyceryl-3 Poly- dimethylsiloxyethyl Dimethicone, Lauryl Pyrrolidone, Lauryl Sultaine, Linoleic Acid, Linolen säure, Leinsäure, Lysin Cocoate, Macadamia Seed Oil Glycereth-8 Esters, Magnesium Coceth Sulfate, Magnesium Coco-Sulfate, Magnesium Isododecylbenzenesulfonate, Magnesium Laureth-11 Carboxylate, Magnesium-Laureth-Sulfat, Magnesium-Laureth-5-Sulfat, Magnesi- um-Laureth-8-Sulfat, Magnesium-Laureth-16-Sulfat, Magnesium-Laureth-3-Sulfosuccinat, Magnesium-Lauryl-Hydroxypropyl-Sulfonat, Magnesium-Lauryl-Sulfat, Magnesium Methyl Cocoyl Taurate, Magnesium Myreth Sulfate, Magnesium Oleth Sulfate, Magnesium/TEA- Coco-Sulfate, Manicouagan Clay, MEA-Cocoate, MEA-Laureth-6 Carboxylate, MEA- Laureth Sulfate, MEA-Laurylsulfat, MEA-PPG-6-Laureth-7-Carboxylat, MEA-PPG-8-Steareth-7- Carboxylat, MEA-Undecylenat, Meroxapol 108, Meroxapol 174, Meroxapol 178, Meroxapol 254, Meroxapol 255, Meroxapol 258, Meroxapol 314, Methoxy-PEG-450-Amidoglutaroyl- Succinimid, Methoxy-PEG-450-Amido-Hydroxysuccinimidyl-Succinamat, Methoxy-PEG-450- Maleimid, Methyl-Morpholin-Oxid, Milkamidopropyl-Amin-Oxid, Milkamidopropyl-Betain, Minkamidopropylamine Oxide, Minkamidopropyl Betaine, MIPA C12-15 Pareth Sulfate, MIPA-Dodecylbenzenesulfonate, MIPA-Laureth Sulfate, MIPA-Lauryl Sulfate, Mixed Isopro panolamines Lanolate, Mixed Isopropanolamines Lauryl Sulfate, Mixed Isopropanolamines Myristate, Morpholine Oleate, Morpholine Stearate, Myreth-3 Carboxylic Acid, Myreth-5 Carboxylic Acid, Myristalkonium Chloride, Myristamidopropylamine Oxide, Myristamidopro- pyl Betaine, Myristamidopropyl Dimethylamine Phosphate, Myristamidopropyl Hydroxysul taine, Myristamidopropyl PG-Dimonium Chloride Phosphate, Myristamine Oxide, Myrista- minopropionic Acid, Myristic Acid, Myristoyl Ethyltrimonium Methosulfate, Myristoyl Glu- tamic Acid, Myristoyl Hydrolyzed Collagen, Myristoyl Sarcosine, Myristyl Betaine, My- ristyl/Cetyl Amine Oxide, Myristyldimoniumhydroxypropyl Cocoglucosides Chloride, My- ristylglucosid, Myristylphosphat, Nonoxynol-20, Nonoxynol-23, Nonoxynol-25, Nonoxynol- 30, Nonoxynol-35, Nonoxynol-40, Nonoxynol-44, Nonoxynol-50, Nonoxynol-100, Nonoxy- nol-120, Nonoxynol-5 Carboxylic Acid, Nonoxynol-8 Carbonsäure, Nonoxynol-10 Carbonsäu re, Nonoxynol-3 Phosphat, Nonoxynol-4 Phosphat, Nonoxynol-6 Phosphat, Nonoxynol-9 Phosphat, Nonoxynol-10 Phosphat, Nonyl Nonoxynol-30, Nonyl Nonoxynol-49, Nonyl Nono- xynol-100, Nonyl Nonoxynol-150, Nonyl Nonoxynol-7 Phosphat, Nonyl Nonoxynol-8 Phos phat, Nonyl Nonoxynol-9 Phosphat, Nonyl Nonoxynol-10 Phosphat, Nonyl Nonoxynol-11 Phosphat, Nonyl Nonoxynol-15 Phosphat, Nonyl Nonoxynol-24 Phosphat, Oatamidopropyl Betain, Octoxynol-16, Octoxynol-25, Octoxynol-30, Octoxynol-33, Octoxynol-40, Octoxynol- 70, Octoxynol-20 Carboxy Acid, Octyldodeceth-20, Octyldodeceth-25, Octyldodeceth-30, Oleamidopropylamine Oxide, Oleamidopropyl Betaine, Oleamidopropyl Hydroxysultaine, Oleamine Oxide, Oleic Acid, Oleoyl Hydrolyzed Collagen, Oleoyl Sarcosine, Oleth-20, Oleth- 23, Oleth-24, Oleth-25, Oleth-30, Oleth-35, Oleth-40, Oleth-44, Oleth-50, Oleth-3- Carbonsäure, Oleth-6-Carbonsäure, Oleth-10-Carbonsäure, Oleylbetain, Olivamidopropyla- minoxid, Olivamidopropylbetain, Olivensäure, Olivoyl Hydrolyzed Wheat Protein, Ophiopo- gon Extract Stearate, Ozonized Oleth-10, Ozonized PEG-10 Oleate, Ozonized PEG-14 Oleate, Ozonized Polysorbate 80, Palm Acid, Palmamidopropyl Betaine, Palmeth-2 Phosphate, Pal- mitamidopropylamine Oxide, Palmitamidopropyl Betaine, Palmitamine Oxide, Palmitic Acid, Palmitoyl Collagen Amino Acids, Palmitoyl Glycine, Palmitoyl Hydrolyzed Collagen, Palmitoyl Hydrolyzed Milk Protein, Palmitoyl Hydrolyzed Wheat Protein, Palmitoyl Keratin Amino A- cids, Palmitoyl Oligopeptide, Palmitoyl Silk Amino Acids, Palmkernsäure, Palmkernamidop- ropyl Betaine, Peach Kernel Oil Glycereth-8 Esters, Peanut Acid, PEG-10 Castor Oil, PEG-40 Rizinusöl, PEG-44 Rizinusöl, PEG-50 Rizinusöl, PEG-54 Rizinusöl, PEG-55 Rizinusöl, PEG-60 Rizinusöl, PEG-80 Rizinusöl, PEG-100 Rizinusöl, PEG-200 Rizinusöl, PEG-11 Cocamide, PEG-6 Cocamide Phosphate, PEG-4 Cocamine, PEG-8 Cocamin, PEG-12 Cocamin, PEG-150 Dibehe- nate, PEG-90 Diisostearate, PEG-75 Dilaurate, PEG-150 Dilaurate, PEG-75 Dioleate, PEG-150 Dioleate, PEG-75 Distearate, PEG-120 Distearate, PEG-150 Distearate, PEG-175 Distearate, PEG-190 Distearate, PEG-250 Distearate, PEG-30 Glyceryl Cocoate, PEG-40 Glyceryl Cocoate, PEG-78 Glyceryl Cocoate, PEG-80 Glyceryl Cocoate, PEG-30 Glyceryl Isostearate, PEG-40 Gly ceryl Isostearate, PEG-50 Glyceryl Isostearate, PEG-60 Glyceryl Isostearate, PEG-90 Glyceryl Isostearate, PEG-23 Glyceryl Laurate, PEG-30 Glyceryl Laurate, PEG-25 Glyceryl Oleate, PEG- 30 Glyceryl Oleate, PEG-30 Glyceryl Soyate, PEG-25 Glyceryl Stearate, PEG-30 Glyceryl Stea rate, PEG-40 Glyceryl Stearate, PEG-120 Glyceryl Stearate, PEG-200 Glyceryl Stearate, PEG- 28 Glyceryl Tallowate, PEG-80 Glyceryl Tallowate, PEG-82 Glyceryl Tallowate, PEG-130 Gly ceryl Tallowate, PEG-200 Glyceryl Tallowate, PEG-45 Hydriertes Rizinusöl, PEG-50 Hydriertes Rizinusöl, PEG-54 Hydriertes Rizinusöl, PEG-55 Hydriertes Rizinusöl, PEG-60 Hydriertes Rizi nusöl, PEG-80 Hydriertes Rizinusöl, PEG-100 Hydriertes Rizinusöl, PEG-200 Hydriertes Rizi nusöl, PEG-30 Hydriertes Lanolin, PEG-70 Hydriertes Lanolin, PEG-50 Hydriertes Palmamid, PEG-2 Isostearat, PEG-3 Isostearat, PEG-4 Isostearat, PEG-6 Isostearat, PEG-8 Isostearat, PEG-10 Isostearat, PEG-12 Isostearat, PEG-20 Isostearat, PEG-30 Isostearat, PEG-40 Isostea rat, PEG- 26 Jojoba -Säure, PEG-40 Jojoba-Säure, PEG-15 Jojoba-Alkohol, PEG-26 Jojoba- Alkohol, PEG-40 Jojoba-Alkohol, PEG-35 Lanolin, PEG-40 Lanolin, PEG-50 Lanolin, PEG-55 Lanolin, PEG-60 Lanolin, PEG- 70 Lanolin, PEG-75 Lanolin, PEG-85 Lanolin, PEG-100 Lanolin, PEG-150 Lanolin, PEG-75 Lanolinöl, PEG-2 Lauramid, PEG-3 Lauraminoxid, PEG-20 Laurat, PEG-32 Laurat, PEG-75 Laurat, PEG-150 Laurat, PEG-70 Mango Glyceride, PEG-20 Mannitan Laurat, PEG-8 Methylether Dimethicone, PEG-120 Methyl Glucose Dioleate, PEG-80 Methyl Glucose Laurate, PEG-120 Methylglucosetrioleat, PEG-4 Montanat, PEG-30 Oieamin, PEG-20 Oleat, PEG-23 Oleat, PEG-32 Oleat, PEG-36 Oleat, PEG-75 Oleat, PEG-150 Oleat, PEG-20 Palmitat, PEG-150 Polyglyceryl-2 Tristearat, PEG/PPG-28/21 Acetatdimethicon, PEG/PPG- 24/18 Butyletherdimethicon, PEG/PPG-3/17 Copolymer, PEG/PPG-5/35 Copolymer, PEG/PPG-8/55 Copolymer, PEG/PPG-10/30 Copolymer, PEG/PPG-10/65 Copolymer, PEG/PPG-12/35 Copolymer, PEG/PPG-16/17 Copolymer, PEG/PPG-20/9 Copolymer, PEG/PPG-20/20 Copolymer, PEG/PPG-20/60 Copolymer, PEG/PPG- 20/65 Copolymer,Lauriminodipropionate, Disodium Lauriminodipropionate Tocopherylphosphate, Disodium Lauroamphodiacetate, Disodium Lauroamphodipropionate, Disodium N-Lauroyl Aspartate, Disodium Lauroyl Glutamate, Disodium Lauryl Phenyl Ether Disulfonate, Disodium Lauryl Sulfosuccinate, Disodium Myristamido MEA-Sulfosuccinate, Disodium Nonoxynol-10, Sulfo succinate Disodium Oleamido MEA-Sulfosuccinate, Disodium Oleamido MIPA- Sulfosuccinate, Disodium Oleamido PEG-2 Sulfosuccinate, Disodium Oleoamphodipropionate, Disodium Oleth-3 Sulfosuccinate, Disodium Oleyl Phosphate, Disodium Oleyl Sulfosuccinate, Disodium Palmitamido PEG-2 Sulfosuccinate, Disodium Palmitoleamido PEG- 2 Sulfo succinate, Disodium PEG-4 Cocamido MIPA-Sulfosuccinate, Disodium PEG-12 Dimethicone Sulfosuccinate, Disodium PEG-8 Palm Glycerides Sulfosuccinate, Disodium PPG-2-Isodeceth- 7 Carboxyamphodiacetate, Disodium Ricinoleamido MEA-Sulfosuccinate, Disodium Sitostereth-14 Sulfosuccinate, Disodium Soyamphodiacetate, Disodium Stearamido MEA- Sulfosuccinate, Disodium Steariminodipropionate, Disodium Stearoamphodiacetate, Disodi Stearoyl Glutamate, Disodium Stearyl Sulfosuccinamate, Disodium Stearyl Sulfosuccina te, Disodium 2-Sulfolaurate, Disodium 2-Sulfopalmitate, Disodium Tallamido MEA- Sulfosuccinate, Disodium Tallowamido MEA-Sulfosuccinate, Disodium Tallowamphodiacetate, Disodium Tallowiminodipropionate, Disodium Tallow Sulfosuccinamate, Disodium Tride- cylsulfosuccinate, Disodium Undecylenamido MEA-Sulfosuccinate, Disodium Undecylenamido PEG-2 Sulfosuccinate, Disodium Undecylenoyl Glutamate, Disodium Wheat Germamido MEA-Sulfosuccinate, Disodium Wheat Germamido PEG-2 Sulfosuccinate, Disodium Wheatgermamphodiacetate, Di-TEA-Cocamide Diacetate, Di- TEA-Oleamido PEG- 2 Sulfosuccinate, Di-TEA-Palmitoyl Aspartate, Ditridecyl Sodium Sulfosuccinate, Dodecylbenzene Sulfonic Acid, Erucamidopropyl Hydroxysultaine, Ethylhexeth-S Carboxylic Acid, Ethyl PEG-15 Cocamine Sulfate, Glyceryl Capryl Ether, Hexyldecanoic Acid, Hydrogenated Coconut Acid, Hydrogenated Laneth -25, Hydrogenated Menhaden Acid, Hydrogenated Palm Acid, Hydrogenated Palm Kernel Amine Oxide, Hydrogenated Tallow Acid, Hydrogenated Tallowamine Oxide, Hydrogenated Tallow Betaine, Hydrogenated Talloweth-25, Hydrogenated Tallowoyl Glutamic Acid, Hydrolyzed Candida Bombicola Extract, Hydroxyceteth-60, Hydroxyethyl Acetomonium PG-Dimethicone, Hydroxyethylbutylamine Laureth Sulfate, Hydroxyethyl Carboxymethyl Cocamidopropylamine, Hydroxyethyl Hydroxypropyl C12-15 Alkoxypropylamine Oxide, Hydroxylauryl/Hydroxymyristyl Betaine, Hydroxystearic Acid, Hydroxysuccinimidyl C10-40 Isoalkyl Acidate, Hydroxysuccinimidyl C21-22 Isoalkyl Acidate, Hydroxysultaines, IPDI /PEG-15 Soyamine Oxide Copolymer, I PDI/PEG-15 Soyethonium Ethosulfate Copolymer, IPDI/PEG-15 Soy Glycinate Copolymer, isoceteth-30, isolaureth-4 phosphate, isopolyglyceryl- 3 dimethicone, isopolyglyceryl-3 dimethiconol, isopropanolamine lanolate, isopropylamine dodecylbenzenesulfonate, isostearamidopropylamine oxide, isostearamidopropyl betaine, isostearamidopropyl Morpholine Oxide, Isosteareth-8, Isosteareth-16, Isosteareth-22, Isosteareth-25, Isosteareth-50, Isostearic Acid, Isostearoyl Hydrolyzed Collagen, Jojoba Oil PEG-150 Esters, Jojoba Wax PEG-80 Esters, Jojoba Wax PEG-120 Esters , Laneth-20, Laneth- 25, Laneth-40, Laneth-50, Laneth-60, Laneth-75, Lanolin Acid, Lauramidopropylamine Oxide, Lauramidopropyl Betaine, Lauramidopropyl Hydroxysultaine, Lauramine Oxide, Lauramino- ropionic Acid, Laurdimoniumhydroxypropyl Decylglucosides Chloride, Laurdimoniumhydro - xypropyl Laurylglucosides Chloride, Laureth-16, Laureth-20, Laureth-21, Laureth-23, Laureth-25, Laureth-30, Laureth-38, Laureth-40, Laureth-3 Carboxylic Aci d, laureth-4 carboxylic acid, laureth-5 carboxylic acid, laureth-6 carboxylic acid, laureth-8 carboxylic acid, laureth-10 carboxylic acid, laureth-11 carboxylic acid, laureth-12 carboxylic acid, laureth-13 carboxylic acid Acid, laureth-14 carboxylic acid, laureth-17 carboxylic acid, laureth-6 citrate, laureth-7 citrate, laureth-1 phosphate, laureth-2 phosphate, laureth-3 phosphate, laureth-4 phosphate, laureth-7 phosphate , Laureth-8 Phosphate, Laureth-7 Tartrate, Laurie Acid, Laurimino Bispropanediol, Lauriminodipropionic Acid, Lauroamphodipropionic Acid, Lauroyl Beta Alanine, Lauroyl Collagen Amino Acids, Lauroyl Ethyltrimonium Methosulfate, Lauroyl Hydrolyzed Collagen, Lauroyl Hydrolyzed Elastin, Lauroyl Methyl Glucamide, Lauroyl Sarcosine, Lauroyl Silk Amino Acids, Lauryl Betaine, Lauryl Dimethicone/Polyglycerol-3 Crosspolymer, Lauryldimonium Hydroxypropyl Cocoglucosides Chloride, Lauryl Glucoside, Laurylglucosides Hydroxypropyltrimonium Chloride, Lauryl Glycol Hydroxypropyl Ether, Lauryl Hydroxysultaine, Lauryl Malamide, Lauryl Methylglucamide, Lauryl/Myristyl Glycol Hydroxypropyl Ether, Lauryl/Myristyl Wheat Bran/Straw Glycosides, Lauryl Polyglyceryl-3 Polymethiconedimethyleoxyethyl , Lauryl Pyrrolidone, Lauryl Sultaine, Linoleic Acid, Linolenic Acid, Leic Acid, Lysine Cocoate, Macadamia Seed Oil Glycereth-8 Esters, Magnesium Coceth Sulfate, Magnesium Coco-Sulfate, Magnesium Isododecylbenzenesulfonate, Magnesium Laureth-11 Carboxylate, Magnesium Laureth Sulfate, magnesium laureth-5 sulfate, magnesium laureth-8 sulfate, magnesium Laureth-16 Sulfate, Magnesium Laureth-3-Sulfosuccinate, Magnesium Lauryl Hydroxypropyl Sulfonate, Magnesium Lauryl Sulfate, Magnesium Methyl Cocoyl Taurate, Magnesium Myreth Sulfate, Magnesium Oleth Sulfate, Magnesium/TEA Coco Sulfate, Manicouagan Clay, MEA Cocoate, MEA Laureth-6 Carboxylate, MEA Laureth Sulfate, MEA Lauryl Sulfate, MEA PPG-6 Laureth-7 Carboxylate, MEA PPG-8 Steareth-7 Carboxylate, MEA Undecylenate, Meroxapol 108, Meroxapol 174, Meroxapol 178, Meroxapol 254, Meroxapol 255, Meroxapol 258, Meroxapol 314, Methoxy PEG 450 Amidoglutaroyl Succinimide, Methoxy PEG 450 Amido Hydroxysuccinimidyl Succinamate, Methoxy PEG 450 Maleimide , Methyl Morpholine Oxide, Milkamidopropyl Amine Oxide, Milkamidopropyl Betaine, Minkamidopropylamine Oxide, Minkamidopropyl Betaine, MIPA C12-15 Pareth Sulfate, MIPA-Dodecylbenzenesulfonate, MIPA-Laureth Sulfate, MIPA-Lauryl Sulfate, Mixed Isoprop panolamines Lanolate, Mixed Isopropanolamines Lauryl Sulfate, Mixed Isopropanolamines Myristate, Morpholine Oleate, Morpholine Stearate, Myreth-3 Carboxylic Acid, Myreth-5 Carboxylic Acid, Myristalkonium Chloride, Myristamidopropylamine Oxide, Myristamidopropyl Betaine, Myristamidopropyl Dimethylamine Phosphate, Myristamidopropyl Hydroxysultaine, Myristamidopropyl PG-Dimonium Chloride Phosphate, Myristamine Oxide, Myristaminopropionic Acid, Myristic Acid, Myristoyl Ethyltrimonium Methosulfate, Myristoyl Glutamic Acid, Myristoyl Hydrolyzed Collagen, Myristoyl Sarcosine, Myristyl Betaine, Myristyl/Cetyl Amine Oxide, Myristyldimoniumhydroxypropyl Cocoglucosides Chloride, Myristylglucoside, Myristylphosphate, Nonoxynol-20, Nonoxynol-23, Nonoxynol- 25, Nonoxynol- 30, Nonoxynol-35, Nonoxynol-40, Nonoxynol-44, Nonoxynol-50, Nonoxynol-100, Nonoxynol-120, Nonoxynol-5 Carboxylic Acid, Nonoxynol-8 Carboxylic Acid, Nonoxynol-10 Carboxylic Acid, Nonoxynol -3 phosphate, nonoxynol-4 phosphate, nonoxynol-6 phosphate, nonoxynol-9 phosphate, nonoxynol-10 phosphate, nonyl nonoxynol-30, nonyl nonoxynol-49, nonyl nonoxy nol-100, nonyl nonoxynol-150, nonyl nonoxynol-7 phosphate, nonyl nonoxynol-8 phosphate, nonyl nonoxynol-9 phosphate, nonyl nonoxynol-10 phosphate, nonyl nonoxynol-11 phosphate, nonyl nonoxynol-15 phosphate, nonyl nonoxynol-24 Phosphate, Oatamidopropyl Betaine, Octoxynol-16, Octoxynol-25, Octoxynol-30, Octoxynol-33, Octoxynol-40, Octoxynol- 70, Octoxynol-20 Carboxy Acid, Octyldodeceth-20, Octyldodeceth-25, Octyldodeceth-30, Oleamidopropylamine Oxide, Oleamidopropyl Betaine, Oleamidopropyl Hydroxysultaine, Oleamine Oxide, Oleic Acid, Oleoyl Hydrolyzed Collagen, Oleoyl Sarcosine, Oleth-20, Oleth-23, Oleth-24, Oleth-25, Oleth-30, Oleth-35, Oleth-40, Oleth-44, Oleth-50, Oleth -3- Carboxylic Acid, Oleth-6 Carboxylic Acid, Oleth-10 Carboxylic Acid, Oleyl Betaine, Olivamidopropylamine Oxide, Olivamidopropyl Betaine, Olivic Acid, Olivoyl Hydrolyzed Wheat Protein, Ophiopogon Extract Stearate, Ozonized Oleth-10, Ozonized PEG-10 Oleate, Ozonized PEG-14 Oleate, Ozonized Polysorbate 80, Palm Acid, Palmamidopropyl Betaine, Palmeth-2 Phosphate, Palmitamidopropylamine Oxide, Palmitamidopropyl Betaine, Palmitamine Oxide, Palmitic Acid, Palmitoyl Collagen Amino Acids, Palmitoyl Glycine, Palmitoyl Hydrolyzed Collagen, Palmitoyl Hydrolyzed Milk Protein , Palmitoyl Hydrolyzed Wheat Protein, Palmitoyl Keratin Amino Acids, Palmitoyl Oligopeptide, Palmitoyl Silk Amino Acids, Palmkernsäure, Palmkernamido- Propyl Betaine, Peach Kernel Oil Glycereth-8 Esters, Peanut Acid, PEG-10 Castor Oil, PEG-40 Castor Oil, PEG-44 castor oil , PEG-50 Castor Oil, PEG-54 Castor Oil, PEG-55 Castor Oil, PEG-60 Castor Oil, PEG-80 Castor Oil, PEG-100 Castor Oil, PEG-200 Castor Oil, PEG-11 Cocamide, PEG-6 Cocamide Phosphate, PEG-4 Cocamine, PEG-8 Cocamine, PEG-12 Cocamine, PEG-150 Dibehenate, PEG-90 Diisostearate, PEG-75 Dilaurate, PEG-150 Dilaurate, PEG-75 Dioleate, PEG-150 Dioleate, PEG-75 Distearate, PEG -120 Distearate, PEG-150 Distearate, PEG-175 Distearate, PEG-190 Distearate, PEG-250 Distearate, PEG-30 Glyceryl Cocoate, PEG-40 Glyceryl Cocoate, PEG-78 Glyceryl Cocoate, PEG-80 Glyceryl Cocoate, PEG- 30 Glyceryl Isostearate, PEG-40 Glyceryl Isostearate, PEG-50 Glyceryl Isostearate, PEG-60 Glyceryl Isostearate, PEG-90 Glyceryl Isostearate, PEG-23 Glyceryl Laurate, PEG-30 Glyceryl Laurate, PEG-25 Glyceryl Oleate, PEG-30 Glyceryl Oleate, PEG-30 Glyceryl Soyate, PEG-25 Glyceryl Stearate, PEG-30 Glyceryl Stearate, PEG-40 Glyceryl Stearate, PEG-120 Glyceryl Stearate, PEG-200 Glyceryl Stearate, PEG-28 Glyceryl Tallowate, PEG-80 Glyceryl Tallowate, PEG-82 Glyceryl Tallowate, PEG-130 Gly ceryl Tallowate, PEG-200 Glyceryl Tallowate, PEG-45 Hydrogenated Castor Oil, PEG-50 Hydrogenated Castor Oil, PEG-54 Hydrogenated Castor Oil, PEG-55 Hydrogenated Castor Oil, PEG-60 Hydrogenated Castor Oil Nut Oil, PEG-80 Hydrogenated Castor Oil, PEG-100 Hydrogenated Castor Oil, PEG-200 Hydrogenated Castor Oil, PEG-30 Hydrogenated Lanolin, PEG-70 Hydrogenated Lanolin, PEG-50 Hydrogenated Palmamide, PEG-2 Isostearate, PEG-3 Isostearate, PEG -4 Isostearate, PEG-6 Isostearate, PEG-8 Isostearate, PEG-10 Isostearate, PEG-12 Isostearate, PEG-20 Isostearate, PEG-30 Isostearate, PEG-40 Isostearate, PEG-26 Jojoba Acid, PEG-40 Jojoba Acid, PEG-15 Jojoba Alcohol, PEG-26 Jojoba Alcohol, PEG-40 Jojoba Alcohol, PEG-35 Lanolin, PEG-40 Lanolin, PEG-50 Lanolin, PEG-55 Lanolin, PEG-60 Lanolin, PEG-70 lanolin, PEG-75 lanolin, PEG-85 lanolin, PEG-100 lanolin, PEG-150 lanolin, PEG-75 lanolin oil, PEG-2 lauramide, PEG-3 lauramine oxide, PEG-20 laurate, PEG-32 laurate, PEG-75 Laurate, PEG-150 Laurate, PEG-70 M ango Glyceride, PEG-20 Mannitan Laurate, PEG-8 Methyl Ether Dimethicone, PEG-120 Methyl Glucose Dioleate, PEG-80 Methyl Glucose Laurate, PEG-120 Methyl Glucose Trioleate, PEG-4 Montanate, PEG-30 Oieamin, PEG-20 Oleate, PEG -23 Oleate, PEG-32 Oleate, PEG-36 Oleate, PEG-75 Oleate, PEG-150 Oleate, PEG-20 Palmitate, PEG-150 Polyglyceryl-2 Tristearate, PEG/PPG-28/21 Acetate Dimethicone, PEG/PPG- 24/18 butyl ether dimethicone, PEG/PPG-3/17 copolymer, PEG/PPG-5/35 copolymer, PEG/PPG-8/55 copolymer, PEG/PPG-10/30 copolymer, PEG/PPG-10/65 copolymer, PEG/PPG-12/35 Copolymer, PEG/PPG-16/17 Copolymer, PEG/PPG-20/9 Copolymer, PEG/PPG-20/20 Copolymer, PEG/PPG-20/60 Copolymer, PEG/PPG- 20/65 Copolymer,
PEG/PPG-22/25 Copolymer, PEG/PPG-28/B0 Copolymer, PEG/PPG-B0-B5 Copolymer,PEG/PPG-22/25 Copolymer, PEG/PPG-28/B0 Copolymer, PEG/PPG-B0-B5 Copolymer,
PEG/PPG-30/55 Copolymer, PEG/PPG-35/40 Copolymer, PEG/PPG-50/40 Copolymer,PEG/PPG-30/55 Copolymer, PEG/PPG-35/40 Copolymer, PEG/PPG-50/40 Copolymer,
PEG/PPG-150/35 Copolymer, PEG/PPG-160/30 Copolymer, PEG/PPG-190/60 Copolymer,PEG/PPG-150/35 Copolymer, PEG/PPG-160/30 Copolymer, PEG/PPG-190/60 Copolymer,
PEG/PPG-200/40 Copolymer, PEG/PPG-300/55 Copolymer, PEG/PPG-20/22 Methyletherdi- methicon, PEG-26-PPG-30 Phosphat, PEG/PPG-4/2 Propylheptylether, PEG/PPG-6/2 Propyl- heptylether, PEG-7/PPG-2 Propylheptylether, PEG/PPG-8/2 Propylheptylether, PEG/PPG- 10/2 Propylheptylether, PEG/PPG-14/2 Propylheptyl Ether, PEG/PPG-40/2 Propylheptyl Ether, PEG/PPG-10/2 Ricinoleate, PEG/PPG-32/3 Ricinoleate, PEG-55 Propylenglycol Oleate, PEG-25 Propylenglycol Stearate, PEG-75 Propylenglycol Stearate, PEG-120 Propylengly- kolstearat, PEG-5 Rapssterin, PEG-10 Rapssterin, PEG-40 Ricinoleamid, PEG-75 Sheabutter- glyceride, PEG-75 Shoreabutterglyceride, PEG-20 Sorbitan Cocoate, PEG-20 Sorbitan Isostea- rate, PEG-40 Sorbitan Lanolat, PEG-75 Sorbitan Lanolat, PEG-10 Sorbitan Laurat, PEG-40 Sorbitan Laurat, PEG-44 Sorbitan Laurat, PEG-75 Sorbitan Laurat, PEG-80 Sorbitan Laurat, PEG-20 Sorbitan Oleat, PEG-80 Sorbitan Palmitate, PEG-40 Sorbitan Stearate, PEG-60 Sor bitan Stearate, PEG-160 Sorbitan Triisostearate, PEG-40 Soy Sterol, PEG-2 Stearamide Car- boxylic Acid, PEG-9 Stearamide Carboxylic Acid, PEG-20 Stearate, PEG-23 Stearate, PEG-25 Stearate, PEG-30 Stearate, PEG-32 Stearate, PEG-35 Stearate, PEG-36 Stearate, PEG-40 Stea rate, PEG-45 Stearate, PEG-50 Stearate, PEG-55 Stearate, PEG-75 Stearate, PEG-90 Stearate, PEG-100 Stearate, PEG- 120 Stearate, PEG-150 Stearate, PEG-45 Stearate Phosphate, PEG- 20 Tallate, PEG-50 Tallow Amide, PEG-2 Tallowamide DEA, PEG-20 Tallowate, PEG-66 Trihyd- roxystearin, PEG-200 Trihydroxystearin, PEG-60 Tsubakiate Glycerides, Pelargonie Acid, Pen- tadoxynol-200, Pheneth-6 Phosphate, Poloxamer 105, Poloxamer 108, Poloxamer 182, Polo- xamer 183, Poloxamer 184, Poloxamer 188, Poloxamer 217, Poloxamer 234, Poloxamer 235, Poloxamer 237, Poloxamer 238, Poloxamer 288, Poloxamer 334, Poloxamer 335, Poloxamer 338, Poloxamin 908, Poloxamin 1508, Polydimethylsiloxy PEG/PPG-24/19 Butyl Ether Sil- sesquioxane, Polydimethylsiloxy PPG-13 Butylether Silsesquioxane, Polyglyceryl-6 Caprate, Polyglyceryl-10 Dilaurate, Polyglyceryl-20 Heptacaprylate, Polyglyceryl-20 Hexacaprylate, Polyglyceryl-2 Lauryl Ether, Polyglyceryl-10 Lauryl Ether, Polyglyceryl-20 Octaisononanoat, Polyglyceryl-6 Pentacaprylat, Polyglyceryl-10 Pentacaprylat, Polyglyceryl-3 Polydimethylsi- loxyethyl Dimethicone, Polyglyceryl-6 Tetracaprylat, Polyglyceryl-10 Tetralaurat, Polyglyce- ryl-6 Tricaprylate, Polyglyceryl-10 Trilaurate, Polyquaternium- 77, Polyquaternium-78, Po- lyquaternium-79, Polyquaternium-80, Polyquaternium-81, Polyquaternium- 82, Pomaderris Kumerahou Flower/Leaf Extract, Poria Cocos Extract, Kalium Abietoyl Hydrolyzed Collagen, Kalium Babassuate, Kalium Behenate, Kalium C9-15 Alkyl Phosphate, Kalium Cll-15 Alkyl Phosphate, Kalium C12-13 Alkyl Phosphate, Kalium-C12-14-Alkylphosphat, Kalium-Caprate, Kalium-Capryloyl-Glutamat, Kalium-Capryloyl-hydrolysiertes Reisprotein, Kalium-Castorat, Kalium-Cocoat, Kalium-Cocoyl-Glutamat, Kalium-Cocoyl-Glycinat, Kalium Cocoyl Hydrolyzed Casein, Kalium Cocoyl Hydrolyzed Collagen, Kalium Cocoyl Hydrolyzed Com Protein, Kalium Cocoyl Hydrolyzed Keratin, Kalium Cocoyl Hydrolyzed Oat Protein, Kalium Cocoyl Hydrolyzed Potato Protein, Kalium Cocoyl Hydrolyzed Rice Bran Protein, Kalium Cocoyl Hydrolyzed Rice Protein, Kalium Cocoyl Hydrolyzed Silk, Kalium Cocoyl Hydrolyzed Soy Protein, Kalium Cocoyl Hydrolyzed Wheat Protein, Kalium Cocoyl Hydrolyzed Yeast Protein, Kalium Cocoyl PCA, Ka lium Cocoyl Sarcosinate, Kalium Cocoyl Taurate, Kalium Cornate, Kalium Cyclocarboxypropy- loleate, Kalium Dihydroxyethyl Cocamine Oxide Phosphate, Kalium Dimethicone PEG-7 Phosphate, Kalium Dodecylbenzenesulfonate, Kalium Hempseedate, Kalium Hydrogenated Cocoate, Kalium Hydrogenated Palmate, Kalium Hydrogenated Tallowate, Kalium- Hydroxystearat, Kalium-Isostearat, Kalium-Lanolat, Kalium-Laurat, Kalium-Laureth-S Car- boxylat, Kalium-Laureth-4 Carboxylat, Kalium-Laureth-5 Carboxylat, Kalium-Laureth-6 Car- boxylat, Kalium Laureth-10 Carboxylate, Kalium Laureth Phosphate, Kalium Lauroyl Collagen Amino Acids, Kalium Lauroyl Glutamate, Kalium Lauroyl Hydrolyzed Collagen, Kalium Lauroyl Hydrolyzed Pea Protein, Kalium Lauroyl Hydrolyzed Soy Protein, Potassium Lauroyl PCA, Po- tassium Lauroyl Pea Amino Acids, Potassium Lauroyl Sarcosinate, Potassium Lauroyl Silk Amino Acids, Potassium Lauroyl Wheat Amino Acids, Kalium Lauryl Phosphate, Kalium Lauryl Sulfate, Kalium Linoleate, Kalium Metaphosphate, Kalium Methyl Cocoyl Taurate, Kalium Myristate, Kalium Myristoyl Glutamate, Kalium Myristoyl Hydrolyzed Collagen, Kalium- Octoxynol-12-Phosphat, Kalium-Oleat, Kalium-Oleoyl-hydrolysiertes Kollagen, Kalium-Olivat, Kalium-Olivoyl-hydrolysiertes Haferprotein, Kalium-Olivoyl-hydrolysiertes Weizenprotein, Kalium-Olivoyl/Lauroyl-Weizenaminosäuren, Kalium Olivoyl PCA, Kalium Palmate, Kalium Palmitate, Kalium Palmitoyl Hydrolyzed Com Protein, Kalium Palmitoyl Hydrolyzed Oat Pro tein, Kalium Palmitoyl Hydrolyzed Rice Protein, Kalium Palmitoyl Hydrolyzed Sweet Almond Protein, Kalium Palmitoyl Hydrolyzed Wheat Protein, Kalium Palm Kernelate, Kalium Peanutate, Kalium Rapeseedate, Potassium Ricinoleate, Potassium Safflowerate, Kalium Soyate, Kalium Stearate, Kalium Stearoyl Hydrolyzed Collagen, Kalium Tallate, Kalium Tallo wate, Kalium Taurate, Kalium Taurine Laurate, Kalium Trideceth-S Carboxylate, Kalium Trideceth-4 Carboxylat, Kalium Trideceth-7 Carboxylat, Kalium Trideceth-15 Carboxylat, Ka lium Trideceth-19 Carboxylat, Kalium Trideceth-6 Phosphat, Kalium Trideceth-7 Phosphat, Potassium Tsubakiate, Potassium Undecylenate, Potassium Undecylenoyl Hydrolyzed Colla gen, Potassium Undecylenoyl Hydrolyzed Rice Protein, PPG-S0-Buteth-S0, PPG-36-Buteth- 36, PPG-38-Buteth-37, PPG-30-Capryleth-4 Phosphate, PPG-10 Cetyletherphosphat, PPG-2- C9-ll-Pareth-8, PPG-l-Deceth-5, PPG-3-Deceth-2-Carbonsäure, PPG-30-Ethylhexeth-4- Phosphat, PPG-20-Glycereth-30, PPG-2-Hydroxyethyl-Coco/lsostearamid, PPG-2-lsodeceth- 8, PPG-2-lsodeceth-10, PPG-2-lsodeceth-18, PPG-2-lsodeceth-25, PPG-4-lsodeceth-10, Pro- pyltrimonium Hydrolyzed Collagen, Quaternium-24, Quaternium-52, Quaternium-87, Raps säure, Reiskleie-Säure, Rice Oil Glycereth-8 Esters, Ricinoleamidopropyl Betaine, Ricinoleic Acid, Ricinoleth-40, Safflower Acid, Sapindus Oahuensis Fruit Extract, Saponaria Officinalis Root Powder, Saponins, Sekken-K, Sekken-Na/K, Sekken Soji, Sekken Soji-K, Sesamöl Glyce- reth-8 Ester, Sesamidopropylamine Oxide, Sesamidopropyl Betaine, Shea Butteramidopro- pyl Betaine, Shea Butter Glycereth-8 Ester, Sodium Arachidate, Sodium Arganampohoaceta- te, Sodium Astrocaryum Murumuruate, Sodium Avocadoate, Sodium Babassuamphoaceta- te, Sodium Babassuate, Sodium Babassu Sulfate, Sodium Behenate, Sodium Bisglycol Ricino- sulfosuccinate, Sodium Bis- Hydroxyethylglycinate Coco-Glucosides Crosspolymer, Sodium Bis-Hydroxyethylglycinate Lauryl- Glucosides Crosspolymer, Sodium Borageamidopropyl PG- Dimonium Chloride Phosphate, Sodium Butoxynol-12 Sulfate, Sodium Butylglucosides Hyd- roxypropyl Phosphate, Natrium-ClB-17-Alkansulfonat, Natrium-C14-18-Alkansulfonat, Nat- rium-C12-15-Alkoxypropyl-lminodipropionat, Natrium-C10-16-Alkylsulfat, Natrium-Cll-15- Alkylsulfat, Natrium-C12-1B-Alkylsulfat, Natrium-C12-15-Alkylsulfat, Natrium-C12-18- Alkylsulfat, Natrium-C16-20-Alkylsulfat, Natrium-C9-22-Alkyl-Sec-Sulfonat, Natrium-C14-17- Alkyl-Sec-Sulfonat, Natrium-Caprat, Natrium-Caproamphoacetat, Natrium- Caproamphohydroxypropylsulfonat, Natrium-Caproamphopropionat, Natrium-PEG/PPG-200/40 Copolymer, PEG/PPG-300/55 Copolymer, PEG/PPG-20/22 Methyl Ether Dimethicone, PEG-26-PPG-30 Phosphate, PEG/PPG-4/2 Propyl Heptyl Ether, PEG/PPG -6/2 propyl heptyl ether, PEG-7/PPG-2 propyl heptyl ether, PEG/PPG-8/2 propyl heptyl ether, PEG/PPG- 10/2 propyl heptyl ether, PEG/PPG-14/2 propyl heptyl ether, PEG/PPG-40 /2 Propylheptyl Ether, PEG/PPG-10/2 Ricinoleate, PEG/PPG-32/3 Ricinoleate, PEG-55 Propylene Glycol Oleate, PEG-25 Propylene Glycol Stearate, PEG-75 Propylene Glycol Stearate, PEG-120 Propylene Glycol Stearate, PEG- 5 Rapeseed sterol, PEG-10 rapeseed sterol, PEG-40 ricinoleamide, PEG-75 shea butter glycerides, PEG-75 shorea butter glycerides, PEG-20 sorbitan cocoate, PEG-20 sorbitan isostearate, PEG-40 sorbitan lanolate, PEG-75 sorbitan lanolate , PEG-10 Sorbitan Laurate, PEG-40 Sorbitan Laurate, PEG-44 Sorbitan Laurate, PEG-75 Sorbitan Laurate, PEG-80 Sorbitan Laurate, PEG-20 Sorbitan Oleate, PEG-80 Sorbitan Palmitate, PEG-40 Sorbitan Stearate, PEG -60 Sorbitan Stearate, PEG-160 Sorbitan Triisostearate, P EG-40 Soy Sterol, PEG-2 Stearamide Carboxylic Acid, PEG-9 Stearamide Carboxylic Acid, PEG-20 Stearate, PEG-23 Stearate, PEG-25 Stearate, PEG-30 Stearate, PEG-32 Stearate, PEG-35 Stearate, PEG-36 stearate, PEG-40 stearate, PEG-45 stearate, PEG-50 stearate, PEG-55 stearate, PEG-75 stearate, PEG-90 stearate, PEG-100 stearate, PEG- 120 stearate, PEG- 150 Stearate, PEG-45 Stearate Phosphate, PEG-20 Tallate, PEG-50 Tallow Amide, PEG-2 Tallowamide DEA, PEG-20 Tallowate, PEG-66 Trihydroxystearin, PEG-200 Trihydroxystearin, PEG-60 Tsubakiate Glycerides, Pelargonium Acid, pentadoxynol-200, pheneth-6 phosphate, poloxamer 105, poloxamer 108, poloxamer 182, poloxamer 183, poloxamer 184, poloxamer 188, poloxamer 217, poloxamer 234, poloxamer 235, poloxamer 237, poloxamer 238,8 poloxamer , Poloxamer 334, Poloxamer 335, Poloxamer 338, Poloxamine 908, Poloxamine 1508, Polydimethylsiloxy PEG/PPG-24/19 Butyl Ether Silsesquioxane, Polydimethylsiloxy PPG-13 Butyl Ether Silsesquioxane, Polyglyceryl -6 Caprate, Polyglyceryl-10 Dilaurate, Polyglyceryl-20 Heptacaprylate, Polyglyceryl-20 Hexacaprylate, Polyglyceryl-2 Lauryl Ether, Polyglyceryl-10 Lauryl Ether, Polyglyceryl-20 Octaisononanoate, Polyglyceryl-6 Pentacaprylate, Polyglyceryl-10 Pentacaprylate, Polyglyceryl-3 Polydimethylsi - loxyethyl Dimethicone, Polyglyceryl-6 Tetracaprylate, Polyglyceryl-10 Tetralaurate, Polyglyceryl-6 Tricaprylate, Polyglyceryl-10 Trilaurate, Polyquaternium- 77, Polyquaternium-78, Polyquaternium-79, Polyquaternium-80, Polyquaternium-81, Polyquaternium- 82, Pomaderis Kumerahou Flower/Leaf Extract, Poria Cocos Extract, Potassium Abietoyl Hydrolyzed Collagen, Potassium Babassuate, Potassium Behenate, Potassium C9-15 Alkyl Phosphate, Potassium Cll-15 Alkyl Phosphate, Potassium C12-13 Alkyl Phosphate, Potassium C12-14 -Alkyl Phosphate, Potassium Caprate, Potassium Capryloyl Glutamate, Potassium Capryloyl Hydrolyzed Rice Protein, Potassium Castorate, Potassium Cocoate, Potassium Cocoyl Glutamate, Potassium Cocoyl Glycinate, Potassium Cocoyl Hydrolyzed Casei n, Potassium Cocoyl Hydrolyzed Collagen, Potassium Cocoyl Hydrolyzed Com Protein, Potassium Cocoyl Hydrolyzed Keratin, Potassium Cocoyl Hydrolyzed Oat Protein, Potassium Cocoyl Hydrolyzed Potato Protein, Potassium Cocoyl Hydrolyzed Rice Bran Protein, Potassium Cocoyl Hydrolyzed Rice Protein, Potassium Cocoyl Hydrolyzed Silk, Potassium Cocoyl Hydrolyzed Soy Protein, Potassium Cocoyl Hydrolyzed Wheat Protein, Potassium Cocoyl Hydrolyzed Yeast Protein, Potassium Cocoyl PCA, Potassium Cocoyl Sarcosinate, Potassium Cocoyl Taurate, Potassium Cornate, Potassium Cyclocarboxypropyl oleate, Potassium Dihydroxyethyl Cocamine Oxide Phosphates, Potassium Dimethicone PEG-7 Phosphate, Potassium Dodecylbenzenesulfonate, Potassium Hempseedate, Potassium Hydrogenated Cocoate, Potassium Hydrogenated Palmate, Potassium Hydrogenated Tallowate, Potassium Hydroxystearate, Potassium Isostearate, Potassium Lanolate, Potassium Laurate, Potassium Laureth-S Car- boxylate, potassium laureth-4 carboxylate, potassium laureth-5 carboxylate, potassium laureth-6 carboxylate, potassium laureth-10 carboxylate, potassium laureth phosphate, potassium lauroyl collagen amino acids, potassium lauroyl glutamate, potassium lauroyl hydrolyzed collagen, Potassium Lauroyl Hydrolyzed Pea Protein, Potassium Lauroyl Hydrolyzed Soy Protein, Potassium Lauroyl PCA, Potassium Lauroyl Pea Amino Acids, Potassium m Lauroyl Sarcosinate, Potassium Lauroyl Silk Amino Acids, Potassium Lauroyl Wheat Amino Acids, Potassium Lauryl Phosphate, Potassium Lauryl Sulfate, Potassium Linoleate, Potassium Metaphosphate, Potassium Methyl Cocoyl Taurate, Potassium Myristate, Potassium Myristoyl Glutamate, Potassium Myristoyl Hydrolyzed Collagen, Potassium Octoxynol -12-Phosphate, Potassium Oleate, Potassium Oleoyl Hydrolyzed Collagen, Potassium Olivate, Potassium Olivoyl Hydrolyzed Oat Protein, Potassium Olivoyl Hydrolyzed Wheat Protein, Potassium Olivoyl/Lauroyl Wheat Amino Acids, Potassium Olivoyl PCA, Potassium Palmate, Potassium Potassium Palmitoyl Hydrolyzed Com Protein, Potassium Palmitoyl Hydrolyzed Oat Protein, Potassium Palmitoyl Hydrolyzed Rice Protein, Potassium Palmitoyl Hydrolyzed Sweet Almond Protein, Potassium Palmitoyl Hydrolyzed Wheat Protein, Potassium Palm Kernelate, Potassium Peanutate, Potassium Rapeseedate, Potassium Ricinoleate, Potassium Safflowerate, Potassium Soyate, Potassium Stearate, Potassium Stearoyl Hydrolyzed Collagen, Potassium Tallate, Potassium Tallo wate, Potassium Taurate, Potassium Taurine Laurate, Potassium Trideceth-S carboxylate, Potassium Trideceth-4 carboxylate, Potassium Trideceth-7 carboxylate, Potassium Trideceth-15 carboxylate, Potassium Trideceth-19 carboxylate, Potassium Trideceth-6 phosphate, Potassium Trideceth- 7 Phosphate, Potassium Tsubakiate, Potassium Undecylenate, Potassium Undecylenoyl Hydrolyzed Collagen, Potassium Undecylenoyl Hydrolyzed Rice Protein, PPG-S0-Buteth-S0, PPG-36-Buteth-36, PPG-38-Buteth-37, PPG-30-Capryleth -4 phosphates, PPG-10 cetyl ether phosphate, PPG-2-C9-ll-pareth-8, PPG-l-deceth-5, PPG-3-deceth-2-carboxylic acid, PPG-30-ethylhexeth-4-phosphate, PPG -20-Glycereth-30, PPG-2-Hydroxyethyl-Coco/Isostearamide, PPG-2-Isodeceth-8, PPG-2-Isodeceth-10, PPG-2-Isodeceth-18, PPG-2-Isodeceth-25, PPG -4-Isodeceth-10, Propyltrimonium Hydrolyzed Collagen, Quaternium-24, Quaternium-52, Quaternium-87, Rapeseed Acid, Rice Bran Acid, Rice Oil Glycereth-8 Esters, Ricinoleamidopropyl Betaine, Ricinoleic Acid, Ricinoleth-40, Safflower Acid, SAP indus Oahuensis Fruit Extract, Saponaria Officinalis Root Powder, Saponins, Sekken-K, Sekken-Na/K, Sekken Soji, Sekken Soji-K, Sesamöl Glycereth-8 Ester, Sesamidopropylamine Oxide, Sesamidopropyl Betaine, Shea Butteramidopropyl Betaine, Shea Butter Glycereth-8 Ester, Sodium Arachidate, Sodium Arganampohoacetate, Sodium Astrocaryum Murumuruate, Sodium Avocadoate, Sodium Babassuamphoacetate, Sodium Babassuate, Sodium Babassu Sulfate, Sodium Behenate, Sodium Bisglycol Ricino-sulfosuccinate, Sodium Bis- Hydroxyethylglycinate Coco-Glucosides crosspolymer, sodium Bis-Hydroxyethylglycinate Lauryl- Glucosides Crosspolymer, Sodium Borageamidopropyl PG- Dimonium Chloride Phosphate, Sodium Butoxynol-12 Sulfate, Sodium Butylglucosides Hydroxypropyl Phosphate, Sodium ClB-17-Alkanesulphonate, Sodium C14-18-Alkanesulphonate, Sodium-C12 -15-Alkoxypropyl iminodipropionate, Sodium C10-16 alkyl sulfate, Sodium C11-15 alkyl sulfate, Sodium C12-1B alkyl sulfate, Sodium C12-15 alkyl sulfate, Sodium C12-18 alkyl sulfate, Sodium C16 -20-Alkyl Sulfate, Sodium C9-22-Alkyl-Sec-Sulphonate, Sodium C14-17- Alkyl-Sec-Sulphonate, Sodium Caprate, Sodium Caproamphoacetate, Sodium Caproamphohydroxypropylsulfonate, Sodium Caproamphopropionate, Sodium
Caproylmethyltaurat, Natrium-Caprylat, Natrium-Capryleth-2-Carboxylat, Natrium- Capryleth-9-Carboxylat, Natrium-Capryloamphoacetat, Natrium-Caproyl methyl taurate, sodium caprylate, sodium capryleth-2-carboxylate, sodium capryleth-9-carboxylate, sodium capryloamphoacetate, sodium
Capryloamphohydroxypropylsulfonat, Natrium-Capryloamphopropionat, Natrium-Capryloamphohydroxypropylsulfonate, Sodium Capryloamphopropionate, Sodium
Capryloylglutamat, Natrium-Capryloylhydrolysiertes Weizenprotein, Natrium-Caprylyl-PG- Sulfonat, Natrium-Caprylylsulfonat, Sodium Castorate, Sodium Ceteareth-13 Carboxylate, Sodium Cetearyl Sulfate, Sodium Ceteth-13 Carboxylate, Sodium Cetyl Sulfate, Sodium Co- camidopropyl PG-Dimonium Chloride Phosphate, Sodium Cocaminopropionate, Sodium Coceth Sulfate, Sodium Coceth-30 Sulfate, Sodium Cocoabutteramphoacetate, Sodium Cocoa Butterate, Sodium Cocoamphoacetate, Sodium Cocoamphohydroxypropylsulfonate, Sodium Cocoamphopropionate, Sodium Cocoate, Natrium-Coco/Babassu/Andiroba-Sulfat, Natrium-Coco/Babassu-Sulfat, Natrium-Cocoglucoside-Hydroxypropylphosphat, Natrium- Cocoglucoside-Hydroxypropylsulfonat, Natrium-Coco-Glucoside-Tartrat, Natrium-Capryloyl Glutamate, Sodium Capryloyl Hydrolyzed Wheat Protein, Sodium Caprylyl PG Sulfonate, Sodium Caprylyl Sulfonate, Sodium Castorate, Sodium Ceteareth-13 Carboxylate, Sodium Cetearyl Sulfate, Sodium Ceteth-13 Carboxylate, Sodium Cetyl Sulfate, Sodium Cocamidopropyl PG-Dimonium Chloride Phosphate, Sodium Cocaminopropionate, Sodium Coceth Sulfate, Sodium Coceth-30 Sulfate, Sodium Cocoabutteramphoacetate, Sodium Cocoa Butterate, Sodium Cocoamphoacetate, Sodium Cocoamphohydroxypropylsulfonate, Sodium Cocoamphopropionate, Sodium Cocoate, Sodium Coco/Babassu/Andiroba Sulfate, Sodium Coco/Babassu Sulfate, Sodium Cocoglucoside Hydroxypropyl Phosphate, Sodium Cocoglucoside Hydroxypropyl Sulfonate, Sodium Cocoglucoside Tartrate, Sodium
Cocoglyceryl-Ether-Sulfonat, Sodium Coco/Hydrogenated Tallow Sulfate, Sodium Cocoimi- nodiacetate, Sodium Cocomonoglyceride Sulfate, Sodium Cocomonoglyceride Sulfonate, Sodium Coco PG-Dimonium Chloride Phosphate, Sodium Coco-Sulfate, Natrium-Cocoyl- Sulfoacetat, Natrium-Cocoyl-Alaninat, Natrium-Cocoyl-Aminosäuren, Natrium-Cocoyl- Kollagen-Aminosäuren, Natrium-Cocoyl-Glutamat, Natrium-Cocoyl-Glutaminat, Natrium- Cocoyl-Glycinat, Sodium Cocoyl/Hydrogenated Tallow Glutamate, Sodium Cocoyl Hydrolyzed Collagen, Sodium Cocoyl Hydrolyzed Keratin, Sodium Cocoyl Hydrolyzed Rice Protein, Sodi um Cocoyl Hydrolyzed Silk, Sodium Cocoyl Hydrolyzed Soy Protein, Sodium Cocoyl hydroly siertes Süßmandelprotein, Natrium-Cocoylhydrolysiertes Weizenprotein, Natrium- Cocoylhydrolysiertes Weizenprotein-Glutamat, Natrium-Cocoyl-Isethionat, Natrium-Cocoyl- Methylaminopropionat, Natrium-Cocoyl-Hafer-Aminosäuren, Natrium-Cocoglyceryl Ether Sulfonate, Sodium Coco/Hydrogenated Tallow Sulfate, Sodium Cocoiminodiacetate, Sodium Cocomonoglyceride Sulfate, Sodium Cocomonoglyceride Sulfonate, Sodium Coco PG-Dimonium Chloride Phosphate, Sodium Coco Sulfate, Sodium Cocoyl Sulfoacetate, Sodium Cocoyl Alaninate , Sodium Cocoyl Amino Acids, Sodium Cocoyl Collagen Amino Acids, Sodium Cocoyl Glutamate, Sodium Cocoyl Glutamate, Sodium Cocoyl Glycinate, Sodium Cocoyl/Hydrogenated Tallow Glutamate, Sodium Cocoyl Hydrolyzed Collagen, Sodium Cocoyl Hydrolyzed Keratin, Sodium Cocoyl Hydrolyzed Rice Protein, Sodium Cocoyl Hydrolyzed Silk, Sodium Cocoyl Hydrolyzed Soy Protein, Sodium Cocoyl Hydrolyzed Sweet Almond Protein, Sodium Cocoyl Hydrolyzed Wheat Protein, Sodium Cocoyl Hydrolyzed Wheat Protein Glutamate, Sodium Cocoyl Isethionate, Sodium Cocoyl Methylaminopropionate, Sodium Cocoyl Oat Amino Acids, Sodium
Cocoyl/Palmoyl/Sunfloweroyl-Glutamat, Natrium-Cocoyl-Prolin, Natrium-Cocoyl-Sarcosinat, Natrium-Cocoyl-Taurat, Natrium-Cocoyl-Threoninat, Natrium-Cocoyl-Weizen-Aminosäuren, Natrium-C12-14-Olefinsulfonat, Natrium-C14-16-Olefinsulfonat, Natrium-C14- 18- Olefinsulfonat, Natrium-C16-18-Olefinsulfonat, Natrium-Cornamphopropionat, Natrium- Cottonseedamphoacetat, Natrium-C13-15-Pareth-8-Butylphosphat, Natrium-C9-ll-Pareth- 6-Carboxylat, Natrium-Cll-15-Pareth-7-Carboxylat, Natrium-C12-13-Pareth-5-Carboxylat, Natrium-C12-13-Pareth-8-Carboxylat, Natrium-C12-13-Pareth-12-Carboxylat, Natrium C12- 15 Pareth-6 Carboxylat, Natrium C12-15 Pareth-7 Carboxylat, Natrium C12-15 Pareth-8 Car- boxylat, Natrium C14-15 Pareth-8 Carboxylat, Natrium C12-14 Sec-Pareth-8 Carboxylat, Nat rium C14-15 Pareth-PG Sulfonat, Natrium C12-13 Pareth-2 Phosphat, Natrium C13-15 Pa- reth-8 Phosphat, Natrium C9-15 Pareth-3 Sulfat, Natrium C10-15 Pareth Sulfat, Natrium C10-16 Pareth-2 Sulfat, Natrium C12-13 Pareth Sulfat, Natrium C12-15 Pareth-Sulfat, Natri um C12-15 Pareth-3-Sulfat, Natrium C13-15 Pareth-3-Sulfat, Natrium C12-14 Sec-Pareth-3- Sulfat, Natrium C12-15 Pareth-3-Sulfonat, Natrium C12-15 Pareth-7-Sulfonat, Natrium C12- 15 Pareth-15-Sulfonat, Sodium Deceth-2 Carboxylate, Sodium Deceth Sulfate, Sodium De- cylbenzenesulfonate, Sodium Decylglucosides Hydroxypropyl Phosphate, Sodium Decylglu- cosides Hydroxypropylsulfonate, Sodium Dilaureth-7 Citrate, Sodium Dilaureth-10 Phospha te, Sodium Dilinoleamidopropyl PG-Dimonium Chloride Phosphate, Sodium Dilinoleate, Sodium Dioleth-8 Phosphate, Sodium Dodecylbenzenesulfonate, Sodium Ethyl 2 Sulfolaura- te, Sodium Glyceryl Oleate Phosphate, Sodium Grapeseedamidopropyl PG-Dimonium Chlo ride Phosphate, Sodium Grapeseedamphoacetate, Sodium Grapeseedate, Sodium Hemp- seedamphoacetate, Sodium Hexeth-4 Carboxylate, Sodium Hydrogenated Cocoate, Sodium Hydrogenated Cocoyl Methyl Isethionate, Sodium Hydrogenated Palmate, Sodium Hydroge nated Tallowate, Sodium Hydrogenated Tallowoyl Glutamate, Sodium Hydroxylauryldimoni- um Ethyl Phosphate, Sodium Hydroxypropyl Palm Kernelate Sulfonate, Sodium Hydroxypro- pylphosphate Decylglucoside Crosspolymer, Sodium Hydroxypropylphosphate Laurylgluco- side Crosspolymer, Sodium Hydroxypropylsulfonate Cocoglucoside Crosspolymer, Natrium- hydroxypropylsulfonat-Decylglucosid-Kreuzpolymer, Natriumhydroxypropylsulfonat-Cocoyl/Palmoyl/Sunfloweroyl Glutamate, Sodium Cocoyl Proline, Sodium Cocoyl Sarcosinate, Sodium Cocoyl Taurate, Sodium Cocoyl Threoninate, Sodium Cocoyl Wheat Amino Acids, Sodium C12-14 Olefin Sulphonate, Sodium C14-16 Olefin Sulfonate, Sodium C14-18 Olefin Sulfonate, Sodium C16-18 Olefin Sulfonate, Sodium Cornamphopropionate, Sodium Cottonseedamphoacetate, Sodium C13-15 Pareth-8-Butyl Phosphate, Sodium C9-II Pareth- 6-Carboxylate, Sodium Cll-15 Pareth-7 Carboxylate, Sodium C12-13 Pareth-5 Carboxylate, Sodium C12-13 Pareth-8 Carboxylate, Sodium C12-13 Pareth-12 carboxylate, sodium C12- 15 pareth-6 carboxylate, sodium C12-15 pareth-7 carboxylate, sodium C12-15 pareth-8 carboxylate, sodium C14-15 pareth-8 carboxylate, sodium C12-14 sec-pareth-8 carboxylate , Sodium C14-15 Pareth-PG Sulfonate, Sodium C12-13 Pareth-2 Phosphate, Sodium C13-15 Pa- reth-8 phosphate, sodium C9-15 pareth-3 sulfate, sodium C10-15 pareth sulfate, sodium C10-16 pareth-2 sulfate, sodium C12-13 pareth sulfate, sodium C12-15 pareth sulfate, sodium C12-15 Pareth-3 Sulfate Sodium C13-15 Pareth-3 Sulfate Sodium C12-14 Sec-Pareth-3 Sulfate Sodium C12-15 Pareth-3 Sulfonate Sodium C12-15 Pareth-7 Sulfonate Sodium C12 - 15 Pareth-15-Sulphonate, Sodium Deceth-2 Carboxylate, Sodium Deceth Sulfate, Sodium Decylbenzenesulfonate, Sodium Decylglucosides Hydroxypropyl Phosphate, Sodium Decylglucosides Hydroxypropylsulfonate, Sodium Dilaureth-7 Citrate, Sodium Dilaureth-10 Phospha te, Sodium Dilinoleamidopropyl PG -Dimonium Chloride Phosphate, Sodium Dilinoleate, Sodium Dioleth-8 Phosphate, Sodium Dodecylbenzenesulfonate, Sodium Ethyl 2 Sulfolaurate, Sodium Glyceryl Oleate Phosphate, Sodium Grapeseedamidopropyl PG-Dimonium Chloride Phosphate, Sodium Grapeseedamphoacetate, Sodium Grapeseedate, Sodium Hemp- seedamphoacetate, Sodium hexeth-4 carboxylates, sodium Hydrogenated Cocoate, Sodium Hydrogenated Cocoyl Methyl Isethionate, Sodium Hydrogenated Palmate, Sodium Hydrogenated Tallowate, Sodium Hydrogenated Tallowoyl Glutamate, Sodium Hydroxylaurydimonium Ethyl Phosphate, Sodium Hydroxypropyl Palm Kernelate Sulfonate, Sodium Hydroxypropylphosphate Decylglucoside Crosspolymer, Sodium Hydroxypropylphosphate Laurylglucoside Crosspolymer, Sodium Hydroxypropylsulfonate Cocoglucoside Crosspolymer, Sodium Hydroxypropylsulfonate-Decylglucoside Crosspolymer, Sodium Hydroxypropylsulfonate-
Laurylglucosid-Kreuzpolymer, Natriumhydroxystearat, Natriumisostearat, Natriumisostea- reth-6-Carboxylat, Sodium Isosteareth- 11 Carboxylate, Sodium Isostearoamphoacetate, Sodium Isostearoamphopropionate, Sodium N- Isostearoyl Methyltaurate, Sodium Laneth Sulfate, Sodium Lanolate, Sodium Lardate, Sodium Lauramido Diacetate, Natrium- Lauraminopropionat, Natrium-Laurat, Natrium-Laureth-3 Carboxylat, Natrium-Laureth-4 Carboxylat, Natrium-Laureth-5 Carboxylat, Natrium-Laureth-6 Carboxylat, Natrium-Laureth- 8 Carboxylat, Natrium-Laureth-11 Carboxylat, Natrium-Laureth-12 Carboxylat, Natrium- Laureth-13 Carboxylat, Natrium-Laureth-14 Carboxylat, Natrium-Laureth-16 Carboxylat, Natrium-Laureth-17 Carboxylat, Natrium-Laureth-Sulfat, Natriumlaureth-5-sulfat, Natrium- laureth-7-sulfat, Natriumlaureth-8-sulfat, Natriumlaureth-12-sulfat, Natriumlaureth-40- sulfat, Natriumlaureth-7-tartrat, Natriumlauriminodipropionat, Natriumlauroamphoacetat, Sodium Lauroamphohydroxypropylsulfonate, Sodium Lauroampho PG-Acetate Phosphate, Sodium Lauroamphopropionate, Sodium Lauroyl Aspartate, Sodium Lauroyl Collagen Amino Acids, Sodium Lauroyl Glycine Propionate, Sodium Lauroyl Hydrolyzed Collagen, Sodium Lauroyl Hydrolyzed Silk, Sodium Lauroyl Hydroxypropyl Sulfonate, Sodium Lauroyl Isethiona te, Sodium Lauroyl Methylaminopropionate, Sodium Lauroyl Methyl Isethionate, Natrium- Lauroyl-Hirse-Aminosäuren, Natrium-Lauroyl/Myristoyl-Aspartat, Natrium-Lauroyl-Hafer- Aminosäuren, Natrium-Lauroyl-Sarkosinat, Natrium-Lauroyl-Seiden-Aminosäuren, Natrium- Lauroyl-Taurat, Sodium Lauroyl Wheat Amino Acids, Sodium Lauryl Diethylenediaminoglyci- nate, Sodium Lauryl Glucose Carboxylate, Sodium Laurylglucosides Hydroxypropyl Phospha te, Sodium Laurylglucosides Hydroxypropylsulfonate, Natrium-Lauryl-Glykol-Carboxylat, Nat- rium-Lauryl-Hydroxyacetamid-Sulfat, Natrium-Lauryl-Phosphat, Natrium-Lauryl-Sulfat, Nat- rium-Lauryl-Sulfoacetat, Natrium-Linoleat, Natrium-Macadamiaseedat, Natrium- Mangoamphoacetat, Sodium Mangoseedate, Sodium/MEA Laureth-2 Sulfosuccinate, Sodi- um Methoxy PPG-2 Acetate, Sodium Methyl Cocoyl Taurate, Sodium Methyl Lauroyl Taura te, Sodium Methyl Myristoyl Taurate, Sodium Methyl Oleoyl Taurate, Sodium Methyl Palmi- toyl Taurate, Sodium Methyl Stearoyl Taurate, Sodium Methyl 2-Sulfolaurate, Sodium Me thyl 2-Sulfopalmitate, Sodium Methyltaurate Isopalmitamide, Sodium Methyltaurine Cocoyl Methyltaurate, Sodium Myreth Sulfate, Sodium Myristate, Sodium Myristoamphoacetate, Sodium Myristoyl Glutamate, Sodium Myristoyl Hydrolyzed Collagen, Sodium Myristoyl I- sethionate, Sodium Myristoyl Sarcosinate, Sodium Myristyl Sulfate, Natrium-Nonoxynol-6- Phosphat, Natrium-Nonoxynol-9-Phosphat, Natrium-Nonoxynol-l-Sulfat, Natrium- Nonoxynol-3-Sulfat, Natrium-Nonoxynol-4-Sulfat, Natrium-Nonoxynol-6-Sulfat, Natrium- Nonoxynol-8-Sulfat, Natrium-Nonoxynol-10-Sulfat, Natrium-Nonoxynol-25-Sulfat, Natrium- Octoxynol-2-Ethansulfonat, Natrium-Octoxynol-2-Sulfat, Natrium-Octoxynol-6-Sulfat, Natri- um-Octoxynol-9-Sulfat, Natrium-Oleat, Sodium Oleoamphoacetate, Sodium Oleoamphohyd- roxypropylsulfonate, Sodium Oleoamphopropionate, Sodium Oleoyl Hydrolyzed Collagen, Sodium Oleoyl Isethionate, Sodium Oleth Sulfate, Sodium Oleyl Methyl Isethionate, Sodium Oleyl Sulfate, Sodium Olivamphoacetate, Sodium Olivate, Sodium Olivoyl Glutamate, Sodi um Palmamphoacetate, Sodium Palmate, Sodium Palm Glyceride Sulfonate, Sodium Palmi- tate, Sodium Palmitoyl Hydrolyzed Collagen, Sodium Palmitoyl Hydrolyzed Wheat Protein, Sodium Palmitoyl Sarcosinate, Sodium Palm Kernelate, Sodium Palm Kerneloyl Isethionate, Sodium Palmoyl Glutamate, Sodium Passiflora Edulis Seedate, Sodium Peanutamphoaceta- te, Sodium Peanutate, Sodium PEG-6 Cocamide Carboxylate, Sodium PEG-8 Cocamide Car- boxylate, Sodium PEG-4 Cocamide Sulfate, Sodium PEG-3 Lauramide Carboxylate, Sodium PEG-4 Lauramide Carboxylate, Natrium-PEG-8-Palmglycerid-Carboxylat, Natrium- Pentaerythritylhydroxypropylminodiacetat-Dendrimer, Natrium-Propoxy-PPG-2-Acetat, Nat rium-Rapsölsäure, Natrium-Risbranamphoacetat, Natrium-Ricinoleat, Natrium Ricinoleo- amphoacetat, Natrium-Hagebuttenamphoacetat, Natrium-Rosinat, Natrium-Safflowerat, Natrium-Saffloweroyl-hydrolysiertes Sojaprotein, Natrium-Sesameseedat, Natrium- Sesamphoacetat, Natrium-Sheabutteramphoacetat, Natrium Soyate, Sodium Soy Hydroly zed Collagen, Sodium Stearate, Sodium Stearoamphoacetate, Sodium Stearoamphohydro- xypropylsulfonate, Sodium Stearoamphopropionate, Sodium Stearoyl Casein, Sodium Ste aroyl Glutamate, Natrium-Stearoyl-Hyaluronat, Natrium-Stearoyl-hydrolysiertes Kollagen, Natrium-Stearoyl-hydrolysiertes Maisprotein, Natrium-Stearoyl-hydrolysierte Seide, Natri- um-Stearoyl-hydrolysiertes Sojaprotein, Natrium-Stearoyl-hydrolysiertes Weizenprotein, Sodium Stearoyl Lactalbumin, Sodium Stearoyl Methyl Isethionate, Sodium Stearoyl Oat Protein, Sodium Stearoyl Pea Protein, Sodium Stearoyl Soy Protein, Sodium Stearyl Dimethyl Glycine, Sodium Stearyl Sulfate, Sodium Sunflowerseedamphoacetate, Sodium Surfactin, Sodium Sweetalmondamphoacetate, Sodium Sweet Almondate, Sodium Tallamphopropio- nate, Sodium Tallate, Sodium Tallowamphoacetate, Sodium Tallowate, Sodium Tallow Sulfa te, Sodium Tamanuseedate, Sodium Taurate, Sodium Taurine Cocoyl Methyltaurate, Sodium Taurine Laurate, Sodium/TEA-Lauroyl Collagen Amino Acids, Sodium/TEA-Lauroyl Hydroly zed Collagen, Natrium/TEA-Lauroyl Hydrolyzed Keratin, Natrium/TEA-Lauroyl Keratin Amino Acids, Natrium/TEA-Undecylenoyl Collagen Amino Acids, Natrium/TEA-Undecylenoyl Hydro- lyzed Collagen, Natrium/TEA-Undecylenoyl Hydrolyzed Com Protein, Natrium/TEA- Undecylenoyl Hydrolyzed Soy Protein, Natrium/TEA-Undecylenoyl Hydrolyzed Wheat Pro tein, Natrium Theobroma Grandiflorum Seedate, Natrium Trideceth-S Carboxylate, Natrium Trideceth-4 Carboxylate, Sodium Trideceth-6 Carboxylate, Sodium Trideceth-7 Carboxylate, Sodium Trideceth-8 Carboxylate, Sodium Trideceth-12 Carboxylate, Sodium Trideceth-15 Carboxylate, Sodium Trideceth-19 Carboxylate, Sodium Trideceth Sulfate, Sodium Tride- cylbenzenesulfonate, Sodium Tridecyl Sulfate, Sodium Trimethylolpropane Hydroxypropyl Iminodiacetate Dendrimer, Sodium Undeceth-5 Carboxylate, Sodium Undecylenate, Sodium Undecylenoamphoacetate, Sodium Undecylenoamphopropionate, Sodium Undecylenoyl Glutamate, Sodium Wheat Germamphoacetate, Sorbeth-160 Tristearate, Soy Acid, So- yamidopropylamine Oxide, Soyamidopropyl Betaine, Soybean Oil Glycereth-8 Esters, Ste- aramidopropylamine Oxide, Stearamidopropyl Betaine, Stearamine Oxide, Steareth-15, Ste- areth-16, Steareth-20, Steareth-21, Steareth-25, Steareth-27, Steareth-30, Steareth- 40, Steareth-50, Steareth-80, Steareth-100, Steareth-2-Phosphat, Steareth-3-Phosphat, Stearin säure, Stearoxypropyltrimoniumchlorid, Stearoylglutaminsäure, Stearoylsarkosin, Stearylbe- tain, Stearyldimoniumhydroxypropylbutylglucosidchlorid, Stearyldimoniumhydroxypropyl Decylglucosides Chloride, Stearyldimoniumhydroxypropyl Laurylglucosides Chloride, Sulfa- ted Castor Oil, Sulfated Coconut Oil, Sulfated Glyceryl Oleate, Sulfatiertes Olivenöl, Sulfatier- tes Erdnussöl, Sunfloweramide MEA, Sunflowerseed Acid, Sunflowerseedamidopropyl Hyd- roxyethyldimonium Chloride, Sunflower Seed Oil Glycereth-8 Esters, Tall Oil Acid, Tallow Acid, Tallowamidopropylamine Oxide, Tallowamidopropyl Betaine, Tallowamidopropyl Hyd- roxysultaine, Tallowamine Oxide, Tallow Betaine, Tallow Dihydroxyethyl Betaine, Tallowoyl Ethyl Glucoside, TEA-Abietoyl Hydrolyzed Collagen, TEA- C12-14-Alkylphosphat, TEA-C10-15- Alkylsulfat, TEA-Cll-15-Alkylsulfat, TEA-C12-13-Alkylsulfat, TEA-C12-14-Alkylsulfat, TEA-C12- 15-Alkylsulfat, TEA-C14-17-Alkylsulfonat, TEA-Canolat, TEA-Cocamiddiacetat, TEA-Cocoat, TEA-Cocoylsulfat, TEA-Cocoyl Alaninat, TEA-Cocoylglutamat, TEA-Cocoyl Glutaminate, TEA- Cocoyl Glycinate, TEA-Cocoyl Hydrolyzed Collagen, TEA-Cocoyl Hydrolyzed Soy Protein, TEA- Cocoyl Sarcosinate, TEA- Dimethicone PEG-7 Phosphate, TEA-Dodecylbenzensulfonat, TEA- Hydrogenated Cocoate, TEA- Hydrogenated Tallowoyl Glutamate, TEA-Isostearate, TEA- Isostearoyl Hydrolyzed Collagen, TEA-Lauraminopropionat, TEA-Laurat, TEA-Laurat/Myristat, TEA-Laurethsulfat, TEA-Lauroyl Collagen Amino Acids, TEA-Lauroyl Glutamate, TEA-Lauroyl Hydrolyzed Collagen, TEA-Lauroyl Keratin Amino Acids, TEA-Lauroyl Methylaminopropiona- te, TEA-Lauroyl/Myristoyl Aspartate, TEA- Lauroyl Sarcosinate, TEA-Lauryl Phosphate, TEA- Lauryl Sulfate, TEA-Myristaminopropionate, TEA- Myristate, TEA-Myristoyl Hydrolyzed Col lagen, TEA-Oleate, TEA-Oleoyl Hydrolyzed Collagen, TEA- Oleoyl Sarcosinate, TEA-Oleyl Sul fate, TEA-Palmitate, TEA-Palm Kernel Sarcosinate, TEA-PEG-3 Cocamide Sulfate, TEA- Rosinate, TEA-Stearate, TEA-Tallate, TEA-T ridecylbenzensulfonat, TEA- Undecylenat, TEA- Undecylenoyl Hydrolyzed Collagen, Tetramethyl Decynediol, Tetrasodium Dicarboxyethyl Stearyl Sulfosuccinamate, TIPA-Laureth Sulfate, TIPA-Lauryl Sulfate, TIPA-Myristate, TIPA- Stearate, Tocopheryl Phosphate, Trehalose Undecylenoate, TM-C12-15 Pareth-2 Phosphate, TM-C12-15 Pareth-6-Phosphat, TM-C12-15 Pareth-8-Phosphat, TM-C12-15 Pareth-10- Phosphat, Trideceth-20, Trideceth-50, Trideceth-3-Carbonsäure, Trideceth-4-Carbonsäure, Trideceth-7-Carbonsäure, Trideceth-8-Carbonsäure, Trideceth-15-Carbonsäure, Trideceth- 19-Carbonsäure, Trideceth-10-Phosphat, Tridecylbenzolsulfonsäure, Trilaureth-9-Citrat, Trimethylolpropanhydroxypropyl-Bis-Hydroxyethylamin-Dendrimer, Trinatrium-Lauryl Glucoside Crosspolymer, Sodium Hydroxystearate, Sodium Isostearate, Sodium Isosteareth-6-Carboxylate, Sodium Isosteareth- 11 Carboxylate, Sodium Isostearoamphoacetate, Sodium Isostearoamphopropionate, Sodium N- Isostearoyl Methyltaurate, Sodium Laneth Sulfate, Sodium Lanolate, Sodium Lardate, Sodium Lauramido Diacetate, Sodium Lauraminopropionate, Sodium laurate, Sodium laureth-3 carboxylate, Sodium laureth-4 carboxylate, Sodium laureth-5 carboxylate, Sodium laureth-6 carboxylate, Sodium laureth- 8 carboxylate, Sodium laureth-11 carboxylate, Sodium Laureth-12 carboxylate, sodium laureth-13 carboxylate, sodium laureth-14 carboxylate, sodium laureth-16 carboxylate, sodium laureth-17 carboxylate, sodium laureth sulfate, sodium laureth-5 sulfate, sodium laureth-7 Sulfate, Sodium Laureth-8 Sulfate, Sodium Laureth-12 Sulfate, Sodium Laureth-40 Sulfate, Sodium Laureth-7 Tartrate, Sodium Lauriminodipropionate, Sodium Lauroamphoacetate, Sodium Lauroamphohydroxypropylsulfonate, Sodium Lauroamph o PG Acetate Phosphate, Sodium Lauroamphopropionate, Sodium Lauroyl Aspartate, Sodium Lauroyl Collagen Amino Acids, Sodium Lauroyl Glycine Propionate, Sodium Lauroyl Hydrolyzed Collagen, Sodium Lauroyl Hydrolyzed Silk, Sodium Lauroyl Hydroxypropyl Sulfonate, Sodium Lauroyl Isethionate, Sodium Lauroyl Methylaminopropionate, Sodium Lauroyl Methyl Isethionate, Sodium Lauroyl Millet Amino Acids, Sodium Lauroyl/Myristoyl Aspartate, Sodium Lauroyl Oat Amino Acids, Sodium Lauroyl Sarcosinate, Sodium Lauroyl Silk Amino Acids, Sodium Lauroyl Taurate, Sodium Lauroyl Wheat Amino Acids, Sodium Lauryl Diethylenediaminoglycinate, Sodium Lauryl Glucose Carboxylate, Sodium Laurylglucosides Hydroxypropyl Phosphate, Sodium Laurylglucosides Hydroxypropylsulfonate, Sodium Lauryl Glycol Carboxylate, Sodium Lauryl Hydroxyacetamide Sulfate, Sodium Lauryl Phosphate, Sodium Lauryl Sulfate, Sodium Lauryl Sulfoacetate, Sodium Linoleate, Sodium Macadamia Seedate, Sodium Mangoamphoacetate, Sodium Mangoseedate, Sodium/MEA Laureth-2 Sulfosuccinate, Sodium Methoxy PPG-2 Acetate, Sodium Methyl Cocoyl Taurate, Sodium Methyl Lauroyl Taurate, Sodium Methyl Myristoyl Taurate, Sodium Methyl Oleoyl Taurate, Sodium Methyl Palmitoyl Taurate, Sodium Methyl Stearoyl Taurate, Sodium Methyl 2-Sulfolaurate, Sodium Methyl 2-Sulfopalmitate, Sodium Methyltaurate Isopalmitamide, Sodium Methyltaurine Cocoyl Methyltaurate, Sodium Myreth Sulfate, Sodium Myristate, Sodium Myristoamphoacetate, Sodium Myristoyl Glutamate, Sodium Myristoyl Hydrolyzed Collagen, Sodium Myristoyl I- sethionate, Sodium Myristoyl Sarcosinate, Sodium Myristyl Sulfate, Sodium Nonoxynol-6-Phosphate, Sodium Nonoxynol-9-Phosphate, Sodium Nonoxynol-1-Sulfate, Sodium Nonoxynol-3-Sulfate, Sodium Nonoxynol-4-Sulfate, Sodium Nonoxynol-6 Sulfate, Sodium Nonoxynol-8 Sulfate, Sodium Nonoxynol-10 Sulfate, Sodium Nonoxynol-25 Sulfate, Sodium Octoxynol-2-Ethanesulfonate, Sodium Octoxynol-2-Sulfate, Sodium ok Toxynol-6-Sulfate, Sodium Octoxynol-9-Sulfate, Sodium Oleate, Sodium Oleoamphoacetate, Sodium Oleoamphohydroxypropylsulfonate, Sodium Oleoamphopropionate, Sodium Oleoyl Hydrolyzed Collagen, Sodium Oleoyl Isethionate, Sodium Oleth Sulfate, Sodium Oleyl Methyl Isethionate, Sodium Oleyl Sulfate, Sodium Olivamphoacetate, Sodium Olivate, Sodium Olivoyl Glutamate, Sodium Palmamphoacetate, Sodium Palmate, Sodium Palm Glyceride Sulfonate, Sodium Palmitate, Sodium Palmitoyl Hydrolyzed Collagen, Sodium Palmitoyl Hydrolyzed Wheat Protein, Sodium Palmitoyl Sarcosinate, Sodium Palm Kernelate, Sodium Palm Kerneloyl Isethionate, Sodium Palmoyl Glutamate, Sodium Passiflora Edulis Seedate, Sodium Peanutamphoacetate, Sodium Peanutate, Sodium PEG-6 Cocamide Carboxylate, Sodium PEG-8 Cocamide Carboxylate, Sodium PEG-4 Cocamide Sulfate, Sodium PEG-3 Lauramide Carboxylate , Sodium PEG-4 Lauramide Carboxylate, Sodium PEG-8 Palm Glyceride Carboxylate, Sodium Pentaerythritylhydroxypropylminodiacetate-D endrimer, sodium propoxy PPG-2 acetate, sodium rapeseed acid, sodium risbran amphoacetate, sodium ricinoleate, sodium ricinoleoamphoacetate, sodium rosehip amphoacetate, sodium rosinate, sodium safflowerate, sodium saffloweroyl hydrolyzed soy protein, sodium -Sesame Seed Date, Sodium Sesamphoacetate, Sodium Shea Butter Amphoacetate, Sodium Soyate, Sodium Soy Hydrolyzed Collagen, Sodium Stearate, Sodium Stearoamphoacetate, Sodium Stearoamphohydroxypropylsulfonate, Sodium Stearoamphopropionate, Sodium Stearoyl Casein, Sodium Stearoyl Glutamate, Sodium Stearoyl Hyaluronate, Sodium -Stearoyl Hydrolyzed Collagen, Sodium Stearoyl Hydrolyzed Corn Protein, Sodium Stearoyl Hydrolyzed Silk, Sodium Stearoyl Hydrolyzed Soy Protein, Sodium Stearoyl Hydrolyzed Wheat Protein, Sodium Stearoyl Lactalbumin, Sodium Stearoyl Methyl Isethionate, Sodium Stearoyl Oat Protein, Sodium Stearoyl Pea Protein, Sodium Stearoyl Soy Protein, Sodium Stearyl Dimethyl Glycine, Sodium Ste aryl Sulfate, Sodium Sunflowerseedamphoacetate, Sodium Surfactin, Sodium Sweetalmondamphoacetate, Sodium Sweet Almondate, Sodium Tallamphopropionate, Sodium Tallate, Sodium Tallowamphoacetate, Sodium Tallowate, Sodium Tallow Sulfa te, Sodium Tamanuseedate, Sodium Taurate, Sodium Taurine Cocoyl Methyltaurate, Sodium Taurine Laurate, Sodium/TEA-Lauroyl Collagen Amino Acids, Sodium/TEA-Lauroyl Hydrolyzed Collagen, Sodium/TEA-Lauroyl Hydrolyzed Keratin, Sodium/TEA-Lauroyl Keratin Amino Acids, Sodium/TEA-Undecylenoyl Collagen Amino Acids, Sodium/TEA-Undecylenoyl Hydrolyzed Collagen, Sodium/TEA-Undecylenoyl Hydrolyzed Com Protein, Sodium/TEA-Undecylenoyl Hydrolyzed Soy Protein, Sodium/TEA-Undecylenoyl Hydrolyzed Wheat Protein, Sodium Theobroma Grandiflorum Seedate, Sodium Trideceth-S carboxylate, Sodium Trideceth-4 carboxylate, Sodium Trideceth-6 carboxylate, Sodium Trideceth-7 carboxylate, Sodium Trideceth-8 carboxylate, Sodium Trideceth-12 carboxylate, Sodium Trideceth-15 carboxylate, Sodium Trideceth-19 Carboxylate, Sodium Trideceth Sulfate, Sodium Tride- cylbenzenesulfonate, Sodium Tridecyl Sulfate, Sodium Trimethylolpropane Hydroxypropyl Iminodiacetate Dendrimer, Sodium Undeceth-5 Carboxylate, Sodium Undecylenate, Sodium Undecylenoamphoacetate, Sodium Undecylenoamphopropionate, Sodium Undecylenoyl Glutamate, Sodium Wheat Germamphoacetate, Tristeth-160, Soy Acid, Soyamidopropylamine Oxide, Soyamidopropyl Betaine, Soybean Oil Glycereth-8 Est ers, Stearamidopropylamine Oxide, Stearamidopropyl Betaine, Stearamine Oxide, Steareth-15, Steareth-16, Steareth-20, Steareth-21, Steareth-25, Steareth-27, Steareth-30, Steareth-40, Steareth-50 , steareth-80, steareth-100, steareth-2-phosphate, steareth-3-phosphate, stearic acid, stearoxypropyltrimonium chloride, stearoylglutamic acid, stearoylsarcosine, stearylbetaine, stearyldimoniumhydroxypropylbutylglucoside chloride, stearyldimoniumhydroxypropyl decylglucosides chloride, stearyldimoniumhydroxypropyl laurylglucosides chloride, sulfated castor oil, Sulfated Coconut Oil, Sulfated Glyceryl Oleate, Sulfated Olive Oil, Sulfated Peanut Oil, Sunfloweramide MEA, Sunflowerseed Acid, Sunflowerseedamidopropyl Hydroxyethyldimonium Chloride, Sunflower Seed Oil Glycereth-8 Esters, Tall Oil Acid, Tallow Acid, Tallowamidopropylamine Oxide, Tallowamidopropyl Betaine, Tallowamidopropyl Hydroxysultaine, Tallowamine Oxide, Tallow Betaine, Tallow Dihydroxyethyl Betaine, Tallowoyl Ethyl Gluc oside, TEA-Abietoyl Hydrolyzed Collagen, TEA- C12-14-alkyl phosphate, TEA-C10-15- alkyl sulphate, TEA-Cll-15-alkyl sulphate, TEA-C12-13-alkyl sulphate, TEA-C12-14-alkyl sulphate, TEA- C12- 15 Alkyl Sulfate, TEA C14-17 Alkyl Sulfonate, TEA Canolate, TEA Cocamide Diacetate, TEA Cocoate, TEA Cocoyl Sulfate, TEA Cocoyl Alaninate, TEA Cocoyl Glutamate, TEA Cocoyl Glutaminate, TEA Cocoyl Glycinate, TEA Cocoyl Hydrolyzed Collagen, TEA Cocoyl Hydrolyzed Soy Protein, TEA Cocoyl Sarcosinate, TEA Dimethicone PEG-7 Phosphate, TEA Dodecylbenzenesulfonate, TEA Hydrogenated Cocoate, TEA Hydrogenated Tallowoyl Glutamate, TEA Isostearate, TEA Isostearoyl Hydrolyzed Collagen, TEA lauraminopropionate, TEA laurate, TEA laurate/myristate, TEA laureth sulfate, TEA lauroyl collagen amino acids, TEA lauroyl glutamate, TEA lauroyl hydrolyzed collagen, TEA lauroyl keratin amino acids, TEA lauroyl methylaminopropionate, TEA-Lauroyl/Myristoyl Aspartate, TEA-Lauroyl Sarcosinate, TEA-Lauryl Phosphate, TEA-Lauryl Sulfate, TEA-Myristaminopropi Onate, TEA-Myristate, TEA-Myristoyl Hydrolyzed Collagen, TEA-Oleate, TEA-Oleoyl Hydrolyzed Collagen, TEA-Oleoyl Sarcosinate, TEA-Oleyl Sulfate, TEA-Palmitate, TEA-Palm Kernel Sarcosinate, TEA-PEG-3 Cocamide Sulfate, TEA- Rosinate, TEA-Stearate, TEA-Tallate, TEA-Tridecylbenzenesulfonate, TEA- Undecylenate, TEA- Undecylenoyl Hydrolyzed Collagen, Tetramethyl Decynediol, Tetrasodium Dicarboxyethyl Stearyl Sulfosuccinamate, TIPA-Laureth Sulfate, TIPA-Lauryl Sulfate, TIPA-Myristate , TIPA- Stearate, Tocopheryl Phosphate, Trehalose Undecylenoate, TM-C12-15 Pareth-2 Phosphate, TM-C12-15 Pareth-6 phosphate, TM-C12-15 Pareth-8 phosphate, TM-C12-15 Pareth-10 phosphate, Trideceth-20, Trideceth-50, Trideceth-3 carboxylic acid, Trideceth-4 - Carboxylic Acid, Trideceth-7 Carboxylic Acid, Trideceth-8 Carboxylic Acid, Trideceth-15 Carboxylic Acid, Trideceth- 19 Carboxylic Acid, Trideceth-10 Phosphate, Tridecylbenzene Sulphonic Acid, Trilaureth-9 Citrate, TrimethylolpropaneHydroxypropyl Bis-Hydroxyethylamine Dendrimer, Trisodium -
Lauroampho-PG-Acetat-Chlorid-Phosphat, Undecansäure, Undeceth-5-Carbonsäure, Unde- cylenamidopropylaminoxid, Undecylenamidopropyl-Betain, Undecylensäure, Undecylenoyl- Kollagenaminosäuren, Undecylenoyl Glycin, Undecylenoyl Hydrolyzed Collagen, Undecy- lenoyl Wheat Amino Acids, Undecyl Glucoside, Wheat Germ Acid, Wheat Germamidopropy- lamine Oxide, Wheat Germamidopropyl Betaine, Yucca Schidigera Leaf/Root/Stem Extract, Yucca Schidigera Stern Extract, Zinc Coceth Sulfatea und Zinc Coco-Sulfate. Lauroampho-PG Acetate Chloride Phosphate, Undecanoic Acid, Undeceth-5-Carbonic Acid, Undecylenamidopropylamine Oxide, Undecylenamidopropyl Betaine, Undecylenic Acid, Undecylenoyl Collagen Amino Acids, Undecylenoyl Glycine, Undecylenoyl Hydrolyzed Collagen, Undecylenoyl Wheat Amino Acids, Undecyl Glucoside, Wheat Germ Acid, Wheat Germamidopropyl- amine Oxide, Wheat Germamidopropyl Betaine, Yucca Schidigera Leaf/Root/Stem Extract, Yucca Schidigera Stern Extract, Zinc Coceth Sulfatea and Zinc Coco-Sulfate.
[0040] Bevorzugte anionische Tenside sind eine oder mehrere Verbindungen, ausgewählt aus der Gruppe bestehend aus Natriumlaurethsulfat, Natriumlaurylsulfat, Natrium- /Kaliumstearat, Natrium-/Kaliumoleat, Natrium-/Kaliumpalmitat, Natrium-/Kaliumpalmat, Natrium-/Kaliumpalmkernelat, Natrium-/Kaliumlinoleat, Natrium-/Kaliumlaurat, Natrium- /Kaliummyristat, Natrium-/Kaliumcaprylat, Natrium-/Kaliumcaprat, Natrium-/Kaliumcocoat, Natrium-/Kalium-C14-16-Olefinsulfonat, Natrium-/Kaliumtallowat, Natrium-/Kaliumlauroyl- isethionat, Natrium-/Kaliumisethionat, Kokosnusssäure, Kokosnussfettsäure C12-18, Palm säure, Palmkernsäure, Stearinsäure, Laurinsäure und Gemische davon. Preferred anionic surfactants are one or more compounds selected from the group consisting of sodium laureth sulfate, sodium lauryl sulfate, sodium/potassium stearate, sodium/potassium oleate, sodium/potassium palmitate, sodium/potassium palmate, sodium/potassium palm kernelate, sodium/ Potassium Linoleate, Sodium/Potassium Laurate, Sodium/Potassium Myristate, Sodium/Potassium Caprylate, Sodium/Potassium Caprate, Sodium/Potassium Cocoate, Sodium/Potassium C14-16 Olefin Sulfonate, Sodium/Potassium Tallowate, Sodium/Potassium Lauroyl Isethionate, Sodium/potassium isethionate, coconut acid, coconut fatty acid C12-18, palm acid, palm kernel acid, stearic acid, lauric acid and mixtures thereof.
[0041] [Bevorzugte amphotere Tenside umfassen Cocamidopropylbetain, Natriumcoco- amphoacetat und deren Mischungen. [0041] [Preferred amphoteric surfactants include cocamidopropyl betaine, sodium cocoamphoacetate, and mixtures thereof.
GEWERBLICHE ANWENDBARKEIT COMMERCIAL APPLICABILITY
[0042] Ein weiterer Gegenstand der Erfindung betrifft ein Verfahren zur Herstellung einer Detergenszubereitung umfassend oder bestehend aus den folgenden Schritten: Another subject of the invention relates to a method for producing a detergent preparation comprising or consisting of the following steps:
(a) Bereitstellen einer Detergensbasis wie oben beschrieben und (a) providing a detergent base as described above and
(b) Einarbeiten der Wirkstoffkapseln wie oben beschrieben in die Basis. (b) Incorporating the active ingredient capsules into the base as described above.
[0043] Unter Einarbeitung ist zu verstehen, dass die Kapseln entweder direkt oder nach Re- Dispergierung in einem geeigneten Lösungsmittel mit der erforderlichen Vorsicht in die Rahmenrezeptur eingerührt und darin homogen verteilt werden, ohne dass es zu einem me chanischen Bruch der Kapseln kommt. [0043] Incorporation means that the capsules are stirred into the base formulation with the necessary care either directly or after redispersion in a suitable solvent and are distributed homogeneously therein without the capsules mechanically breaking.
[0044] Ebenfalls beansprucht wird die Verwendung von Wirkstoffkapseln wie oben beschrie ben zur Herstellung von Detergenszubereitungen. Also claimed is the use of active ingredient capsules as described above for the production of detergent preparations.
[0045] Der guten Ordnung halber sei darauf hingewiesen, dass alle oben genannten bevor zugten Ausführungsformen, insbesondere bevorzugte Ausgangsstoffe, Mischungen, Men genangaben und dergleichen auch für das beanspruchte Verfahren sowie die beanspruchte Verwendung mitgelten, ohne dass es einer Wiederholung bedarf. BEISPIELE For the sake of good order, it should be pointed out that all the above-mentioned preferred embodiments, particularly preferred starting materials, mixtures, quantities and the like also apply to the claimed method and the claimed use, without the need to repeat them. EXAMPLES
Beispiel 1 Wirkstoffkapsein auf Aigmatbasis Example 1 Active ingredient capsules based on Aigmat
Die Komponenten der Phase A wurden in Wasser vorgelegt und zu einer homogenen Prä- Emulsion verarbeitet. Anschließend wurden der Emulgator sowie der Träger (Phase B) hinzu gegeben und ebenfalls unter Rühren homogenisiert. Im dritten Schritt wurde Phase C hinzu gegeben und der Träger mit den Farbstoffpartikeln beladen. Die Zusammensetzung der Ge- samtmischung ist in Tabelle 1 wiedergegeben. The components of phase A were placed in water and processed into a homogeneous pre-emulsion. Then the emulsifier and the carrier (phase B) were added and also homogenized with stirring. In the third step, phase C was added and the carrier was loaded with the dye particles. The composition of the overall mixture is given in Table 1.
Tabelle 1 Table 1
Zusammensetzung Wirkstoffkapseln (Mengenangaben als Gew.-%) Composition of active ingredient capsules (quantities as % by weight)
Die Mischung wurde anschließend in ein Bad bestehend aus einer 30 Gew.-%igen wässrigen Calciumchlorid-Lösung vertropft wobei die Kapseln aushärteten. Nach etwa 30 Minuten wur den die intensiv grün gefärbten Kapseln abfiltriert und getrocknet. Danach waren sie zur Ein arbeitung in eine Detergensbasis bereit. Beispiel 2 The mixture was then dropped into a bath consisting of a 30% strength by weight aqueous calcium chloride solution, during which the capsules hardened. After about 30 minutes, the intensively green colored capsules were filtered off and dried. Thereafter they were ready for incorporation into a detergent base. example 2
Wirkstoffkapsein auf Aigmatbasis Active ingredient capsules based on Aigmat
Beispiel 1 wurde wiederholt. Die Zusammensetzung der Gesamtmischung ist in Tabelle 2 wiedergegeben. Example 1 was repeated. The composition of the overall mixture is given in Table 2.
Tabelle 2 Table 2
Zusammensetzung Wirkstoffkapseln (Mengenangaben als Gew.-%) Die Mischung wurde anschließend in ein Bad bestehend aus einer 30 Gew.-%igen wässrigen Calciumchlorid-Lösung vertropft wobei die Kapseln aushärteten. Nach etwa 30 Minuten wur den die intensiv rot gefärbten Kapseln abfiltriert und getrocknet. Danach waren sie zur Einar beitung in eine Detergensbasis bereit. Composition of active ingredient capsules (quantities as % by weight) The mixture was then dropped into a bath consisting of a 30% strength by weight aqueous calcium chloride solution, during which the capsules hardened. After about 30 minutes, the intensely red colored capsules were filtered off and dried. Thereafter they were ready for incorporation into a detergent base.
Beispiel 3 Example 3
Wirkstoffkapsein auf Chitosanbasis Active ingredient capsules based on chitosan
Die Komponenten der Phase A wurden in Wasser vorgelegt und zu einer homogenen Prä- Emulsion verarbeitet. Anschließend wurden der Emulgator sowie der Träger (Phase B) hinzu- gegeben und ebenfalls unter Rühren homogenisiert. Im dritten Schritt wurde Phase C hinzu gegeben und der Träger mit den Farbstoffpartikeln beladen. Die Zusammensetzung der Ge samtmischung ist in Tabelle 3 wiedergegeben. The components of phase A were placed in water and processed into a homogeneous pre-emulsion. The emulsifier and the carrier (phase B) were then added and also homogenized with stirring. In the third step, phase C was added and the carrier was loaded with the dye particles. The composition of the overall mixture is given in Table 3.
Tabelle 3 Zusammensetzung Wirkstoffkapseln (Mengenangaben als Gew.-%) Table 3 Composition of active ingredient capsules (quantities as % by weight)
Die Mischung wurde anschließend in ein Bad bestehend aus einer 30 Gew.-%igen wässrigen Natriumalginat-Lösung vertropft wobei die Kapseln aushärteten. Nach etwa 30 Minuten wur- den die intensiv blau gefärbten Kapseln abfiltriert und getrocknet. Danach waren sie zur Ein arbeitung in eine Detergensbasis bereit. FORMULIERUNGSBEISPIELE The mixture was then dropped into a bath consisting of a 30% strength by weight aqueous sodium alginate solution, during which the capsules hardened. After about 30 minutes, the intensively blue-colored capsules were filtered off and dried. Thereafter they were ready for incorporation into a detergent base. FORMULATION EXAMPLES
Tabelle Fl Table Fl
Flüssigseife (Mengen in Gew.-%) Liquid soap (amounts in % by weight)
Table F2 Table F2
Syndetseife (Mengen in Gew.-%) Table F3 Syndet soap (amounts in % by weight) Table F3
Flüssigseife (Mengen in Gew.-%) Liquid soap (amounts in % by weight)
Table F4 Table F4
Körperreinigungsmittel mit Triclosan (Mengen in Gew.-%) Table F5 Body cleansers with triclosan (amounts in % by weight) Table F5
Körperreinigungsmittel (Mengen in Gew.-%) Body cleansers (amounts in % by weight)
Table F6 Table F6
Flüssigseife (Mengen als Gew.-%) Liquid soap (amounts as % by weight)

Claims

PATENTANSPRÜCHE PATENT CLAIMS
1. Wirkstoffkapseln, dadurch erhältlich oder erhalten, indem man 1. Active ingredient capsules, thereby obtainable or obtained by
(i) eine wässrige Emulsion bereitstellt, enthaltend (i) providing an aqueous emulsion containing
(a) wenigstens eine mikrokristalline Faser, (a) at least one microcrystalline fiber,
(b) wenigstens einen Wirkstoff, (b) at least one active substance,
(c) wenigstens einen Farbstoff und (c) at least one dye and
(d) wenigstens einen Gelbildner; (d) at least one gelling agent;
(ii) die Emulsion in ein Härtungsbad unter Ausbildung von Kapseln vertropft und(ii) dripping the emulsion into a hardening bath to form capsules and
(iii) die Kapseln anschließend abtrennt und gegebenenfalls trocknet. (iii) subsequently separating the capsules and optionally drying them.
2. Verfahren zur Herstellung von Wirkstoffkapseln, umfassend oder bestehend aus den folgenden Schritten: 2. Process for the production of active ingredient capsules, comprising or consisting of the following steps:
(i) Bereitstellen einer wässrigen Emulsion, enthaltend (i) providing an aqueous emulsion containing
(a) wenigstens eine mikrokristalline Faser, (a) at least one microcrystalline fiber,
(b) wenigstens einen Wirkstoff, (b) at least one active substance,
(c) wenigstens einen Farbstoff und (c) at least one dye and
(d) wenigstens einen Gelbildner; (d) at least one gelling agent;
(ii) Vertropfen der Emulsion in ein Härtungsbad unter Ausbildung von Kapseln; und(ii) dripping the emulsion into a hardening bath to form capsules; and
(iii) Abtrennen und gegebenenfalls Trocknen der Kapseln. (iii) separating and optionally drying the capsules.
3. Verfahren nach Anspruch 2, dadurch gekennzeichnet, dass man mikrokristalline Fa sern einsetzt, die eine Länge von etwa 100 bis etwa 1.500 pm aufweisen. 3. The method according to claim 2, characterized in that microcrystalline fibers are used which have a length of about 100 to about 1,500 μm.
4. Verfahren nach den Ansprüchen 2 und/oder 3, dadurch gekennzeichnet, dass man als mikrokristalline Fasern mikrokristalline Cellulose einsetzt. 4. Process according to Claims 2 and/or 3, characterized in that microcrystalline cellulose is used as the microcrystalline fibers.
5. Verfahren nach mindestens einem der Ansprüche 2 bis 4, dadurch gekennzeichnet, dass man Wirkstoffe einsetzt, die ausgewählt sind aus der Gruppe, die gebildet wird von Parfümstoffen und/oder antimikrobiellen Wirkstoffen. 5. The method according to at least one of claims 2 to 4, characterized in that active ingredients are used which are selected from the group formed by perfumes and/or antimicrobial active ingredients.
6. Verfahren nach mindestens einem der Ansprüche 2 bis 5, dadurch gekennzeichnet, dass man als Farbstoffe Pigmente einsetzt, deren Partikeldurchmesser um den Faktor 10 bis 100 kleiner ist, als die Länge der mikrokristallinen Fasern. 6. The method according to at least one of claims 2 to 5, characterized in that the dyes used are pigments whose particle diameter is smaller by a factor of 10 to 100 than the length of the microcrystalline fibers.
7. Verfahren nach mindestens einem der Ansprüche 2 bis 6, dadurch gekennzeichnet, dass man als Gelbildner Alginsäure oder Chitosan oder deren Salze einsetzt. 7. The method according to at least one of claims 2 to 6, characterized in that the gel former used is alginic acid or chitosan or their salts.
8. Verfahren nach mindestens einem der Ansprüche 2 bis 7, dadurch gekennzeichnet, dass man der Emulsion weiterhin noch Emulgatoren und/oder Verdickungsmittel zu setzt. 8. Process according to at least one of Claims 2 to 7, characterized in that emulsifiers and/or thickeners are also added to the emulsion.
9. Verfahren nach mindestens einem der Ansprüche 2 bis 8, dadurch gekennzeichnet, dass man Emulsionen einsetzt, die 9. The method according to at least one of claims 2 to 8, characterized in that emulsions are used which
(a) etwa 0,5 bis etwa 5 Gew.-% mikrokristalline Fasern, (a) from about 0.5% to about 5% by weight microcrystalline fibers,
(b) etwa 0,5 bis etwa 5 Gew.-% Wirkstoffe, (b) from about 0.5% to about 5% by weight of active ingredients,
(c) etwa 1 bis etwa 5 Gew.-% Farbstoffe, (c) from about 1% to about 5% by weight of dyes,
(d) etwa 0,5 bis etwa 5 Gew.-%Gelbildner; (d) from about 0.5% to about 5% by weight of gelling agent;
(e) 0 bis etwa 5 Gew.-% Emulgatoren und (e) 0% to about 5% by weight emulsifiers and
(f) 0 bis etwa 1 Gew.-% Verdickungsmittel mit der Maßgabe enthalten, dass sich alle Mengenangaben mit Wasser und gegebe nenfalls weiteren Lösungsmitteln zu 100 Gew.-% ergänzen (f) contain 0 to about 1% by weight of thickener, with the proviso that all stated quantities add up to 100% by weight with water and, if appropriate, other solvents
10. Verfahren nach mindestens einem der Ansprüche 2 bis 9, dadurch gekennzeichnet, dass man Emulsionen, die Alginsäure oder deren Salze als Gelbildner enthalten, in eine wässrige Calciumchloridlösung vertropft. 10. Process according to at least one of Claims 2 to 9, characterized in that emulsions containing alginic acid or salts thereof as gel formers are added dropwise to an aqueous calcium chloride solution.
11. Verfahren nach mindestens einem der Ansprüche 2 bis 10, dadurch gekennzeichnet, dass man Emulsionen, die Chitosan oder dessen Salze als Gelbildner enthalten, in eine wässrige Alginsäure- oder Alginatlösung vertropft. 11. The method according to at least one of claims 2 to 10, characterized in that emulsions containing chitosan or its salts as gel formers are added dropwise to an aqueous alginic acid or alginate solution.
12. Detergenszubereitungen enthaltend die Wirkstoffkapseln nach Anspruch 1. 12. detergent preparations containing the active ingredient capsules according to claim 1.
13. Zubereitungen nach Anspruch 12, dadurch gekennzeichnet, dass es sich um eine Sei fenbasis, eine Stückseife, eine Syndetseife, eine Flüssigseife oder eine Cremeseife han delt. 13. Preparations according to claim 12, characterized in that it is a soap base, a bar soap, a syndet soap, a liquid soap or a cream soap.
14. Verfahren zur Herstellung einer Detergenszubereitung umfassend oder bestehend aus den folgenden Schritten: 14. A method for producing a detergent preparation comprising or consisting of the following steps:
(a) Bereitstellen einer Detergensbasis und (a) providing a detergent base and
(b) Einarbeiten der Wirkstoffkapseln gemäß Anspruch 1 in die Basis. (b) incorporating the active substance capsules according to claim 1 into the base.
15. Verwendung von Wirkstoffkapseln nach Anspruch 1 zur Herstellung von Detergenszu bereitungen. 15. Use of active ingredient capsules according to claim 1 for the production of Detergenszu preparations.
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HU221435B (en) 1998-02-20 2002-10-28 Egyt Gyogyszervegyeszeti Gyar Pellet-based pharmaceutical composition of controlled release with high content of potassium-chloride, and process for it's production
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