BR9813048B1 - processo para a preparação de um composto. - Google Patents

processo para a preparação de um composto.

Info

Publication number
BR9813048B1
BR9813048B1 BRPI9813048-0A BR9813048A BR9813048B1 BR 9813048 B1 BR9813048 B1 BR 9813048B1 BR 9813048 A BR9813048 A BR 9813048A BR 9813048 B1 BR9813048 B1 BR 9813048B1
Authority
BR
Brazil
Prior art keywords
compound
preparation
Prior art date
Application number
BRPI9813048-0A
Other languages
English (en)
Portuguese (pt)
Other versions
BR9813048A (pt
Inventor
Martin Francis Jones
Christopher John Wallis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BR9813048A publication Critical patent/BR9813048A/pt
Publication of BR9813048B1 publication Critical patent/BR9813048B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI9813048-0A 1997-10-14 1998-10-14 processo para a preparação de um composto. BR9813048B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9721780.6A GB9721780D0 (en) 1997-10-14 1997-10-14 Process for the synthesis of chloropurine intermediates
PCT/GB1998/003080 WO1999019327A1 (en) 1997-10-14 1998-10-14 Process for the synthesis of chloropurine intermediates

Publications (2)

Publication Number Publication Date
BR9813048A BR9813048A (pt) 2000-08-15
BR9813048B1 true BR9813048B1 (pt) 2010-07-13

Family

ID=10820547

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9813048-0A BR9813048B1 (pt) 1997-10-14 1998-10-14 processo para a preparação de um composto.

Country Status (43)

Country Link
US (1) US6646125B1 (en:Method)
EP (1) EP1023292B1 (en:Method)
JP (1) JP4531250B2 (en:Method)
KR (1) KR100543845B1 (en:Method)
CN (1) CN1160354C (en:Method)
AP (1) AP1182A (en:Method)
AR (1) AR014921A1 (en:Method)
AT (1) ATE249461T1 (en:Method)
AU (1) AU738462B2 (en:Method)
BG (1) BG64597B1 (en:Method)
BR (1) BR9813048B1 (en:Method)
CA (1) CA2306958C (en:Method)
CO (1) CO4980899A1 (en:Method)
CZ (1) CZ294482B6 (en:Method)
DE (1) DE69818084T2 (en:Method)
DK (1) DK1023292T3 (en:Method)
EA (1) EA003183B1 (en:Method)
EE (1) EE04059B1 (en:Method)
EG (1) EG21730A (en:Method)
ES (1) ES2205553T3 (en:Method)
GB (1) GB9721780D0 (en:Method)
GE (1) GEP20022679B (en:Method)
HR (1) HRP20000216B1 (en:Method)
HU (1) HUP0003984A3 (en:Method)
ID (1) ID24927A (en:Method)
IL (1) IL135323A (en:Method)
IN (1) IN184590B (en:Method)
IS (1) IS2195B (en:Method)
MA (1) MA24676A1 (en:Method)
MY (1) MY127470A (en:Method)
NO (1) NO325030B1 (en:Method)
NZ (1) NZ503679A (en:Method)
OA (1) OA11370A (en:Method)
PE (1) PE121899A1 (en:Method)
PL (1) PL188477B1 (en:Method)
PT (1) PT1023292E (en:Method)
RS (1) RS49710B (en:Method)
SK (1) SK285331B6 (en:Method)
TR (1) TR200000976T2 (en:Method)
TW (1) TW436488B (en:Method)
UA (1) UA54550C2 (en:Method)
WO (1) WO1999019327A1 (en:Method)
ZA (1) ZA989338B (en:Method)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK284596B6 (sk) * 1997-11-27 2005-07-01 Lonza Ag Spôsob výroby (1S,4R)- alebo (1R,4S)-4-(2-amino-6-chlór-9-H- purin-9-yl)-2-cyklopentén-1-metanolu alebo jeho solí
FR2849030A1 (fr) * 2002-12-20 2004-06-25 Isochem Sa Procede de preparation des n-(2-amino-4, 6-dihalogenopyrimidin-5-yl) formamides
GB0320738D0 (en) * 2003-09-04 2003-10-08 Glaxo Group Ltd Novel process
CN100465174C (zh) * 2006-06-13 2009-03-04 中国科学院上海有机化学研究所 制备光学纯阿巴卡韦的方法
KR101109476B1 (ko) * 2009-06-26 2012-01-31 현대제철 주식회사 실린더 교체용 지그장치
ME03058B (me) 2010-01-27 2019-01-20 Viiv Healthcare Co Antivirusna terapija
CN104672239A (zh) * 2013-11-26 2015-06-03 上海迪赛诺化学制药有限公司 一种采用一锅法制备阿巴卡韦式v中间体的工艺

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268672A (en) * 1977-02-09 1981-05-19 The Regents Of The University Of Minnesota Adenosine deaminase resistant antiviral purine nucleosides and method of preparation
JPS6175A (ja) * 1984-03-06 1986-01-06 ブリストル−マイア−ズ　コムパニ− 神経弛緩剤、１‐フルオロフェニルブチル‐４‐（５‐ハロ‐２‐ピリミジニル）ピペラジン誘導体
DE3901502C2 (de) * 1988-01-20 2002-06-13 Univ Minnesota Didesoxydehydrocarbocyclische Nucleoside, diese enthaltende pharmazeutische Formulierungen und Pyrimidinylamino-cyclopentenylcarbinol-Derivate
US5631370A (en) * 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
NZ229453A (en) * 1988-06-10 1991-08-27 Univ Minnesota & Southern Rese A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
MY104575A (en) 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
US5126452A (en) * 1990-04-06 1992-06-30 Glaxo Inc. Synthesis of purine substituted cyclopentene derivatives
US5329008A (en) * 1993-04-07 1994-07-12 Glaxo Inc. Synthesis of a 3,4-dihydroxy-1-cyclopentanylpurinone
GB9402161D0 (en) * 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
SK285229B6 (sk) * 1997-05-13 2006-09-07 Lonza Ag Spôsob výroby derivátov (1R,4S)- alebo (1S,4R)-1-amino-4- (hydroxymetyl)-2-cyklopenténu a enantioméru (1R,4S)-N-butyryl-1- amino-4-(hydroxymetyl)-2-cyklopenténu

Also Published As

Publication number Publication date
SK285331B6 (sk) 2006-11-03
EG21730A (en) 2002-02-27
CZ294482B6 (cs) 2005-01-12
DK1023292T3 (da) 2003-11-10
EP1023292B1 (en) 2003-09-10
EA003183B1 (ru) 2003-02-27
IL135323A0 (en) 2001-05-20
EE04059B1 (et) 2003-06-16
CA2306958C (en) 2007-09-04
CO4980899A1 (es) 2000-11-27
KR20010015744A (ko) 2001-02-26
GEP20022679B (en) 2002-04-25
IS5423A (is) 2000-03-28
BG64597B1 (bg) 2005-08-31
HRP20000216B1 (en) 2002-08-31
EA200000318A1 (ru) 2000-12-25
UA54550C2 (uk) 2003-03-17
NO20001896D0 (no) 2000-04-12
US6646125B1 (en) 2003-11-11
NO20001896L (no) 2000-06-13
AP2000001790A0 (en) 2000-06-30
CA2306958A1 (en) 1999-04-22
AP1182A (en) 2003-06-18
MY127470A (en) 2006-12-29
HUP0003984A3 (en) 2002-12-28
MA24676A1 (fr) 1999-07-01
AU738462B2 (en) 2001-09-20
CN1281457A (zh) 2001-01-24
CZ20001367A3 (cs) 2000-10-11
IL135323A (en) 2004-07-25
CN1160354C (zh) 2004-08-04
GB9721780D0 (en) 1997-12-10
WO1999019327A1 (en) 1999-04-22
HUP0003984A2 (hu) 2001-04-28
ID24927A (id) 2000-08-31
YU20200A (sh) 2003-02-28
NZ503679A (en) 2002-09-27
PL188477B1 (pl) 2005-02-28
IS2195B (is) 2007-01-15
HRP20000216A2 (en) 2000-08-31
JP2001519432A (ja) 2001-10-23
PT1023292E (pt) 2004-02-27
EE200000162A (et) 2001-04-16
AR014921A1 (es) 2001-04-11
PE121899A1 (es) 1999-12-20
IN184590B (en:Method) 2000-09-09
SK5362000A3 (en) 2001-03-12
DE69818084D1 (de) 2003-10-16
ATE249461T1 (de) 2003-09-15
TW436488B (en) 2001-05-28
AU9547698A (en) 1999-05-03
PL339904A1 (en) 2001-01-15
HK1027807A1 (en) 2001-01-23
KR100543845B1 (ko) 2006-01-23
BR9813048A (pt) 2000-08-15
NO325030B1 (no) 2008-01-21
RS49710B (sr) 2007-12-31
OA11370A (en) 2004-01-27
TR200000976T2 (tr) 2000-11-21
BG104352A (en) 2001-02-28
EP1023292A1 (en) 2000-08-02
ZA989338B (en) 2000-04-13
ES2205553T3 (es) 2004-05-01
DE69818084T2 (de) 2004-07-15
JP4531250B2 (ja) 2010-08-25

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 13/07/2010, OBSERVADAS AS CONDICOES LEGAIS.

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 13.07.2020