BR9712988A - Imunoterapia do câncer usando células tumorais combinadas com mistura de linfócitos - Google Patents
Imunoterapia do câncer usando células tumorais combinadas com mistura de linfócitosInfo
- Publication number
- BR9712988A BR9712988A BR9712988-7A BR9712988A BR9712988A BR 9712988 A BR9712988 A BR 9712988A BR 9712988 A BR9712988 A BR 9712988A BR 9712988 A BR9712988 A BR 9712988A
- Authority
- BR
- Brazil
- Prior art keywords
- tumor
- lymphocytes
- cancer immunotherapy
- patient
- stimulated
- Prior art date
Links
- 210000004698 lymphocyte Anatomy 0.000 title abstract 5
- 210000004881 tumor cell Anatomy 0.000 title abstract 4
- 238000002619 cancer immunotherapy Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 6
- 239000000427 antigen Substances 0.000 abstract 4
- 102000036639 antigens Human genes 0.000 abstract 4
- 108091007433 antigens Proteins 0.000 abstract 4
- 230000000735 allogeneic effect Effects 0.000 abstract 3
- 230000005975 antitumor immune response Effects 0.000 abstract 1
- 229940030156 cell vaccine Drugs 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000004044 response Effects 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/47—Brain; Nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/49—Breast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/50—Cellular immunotherapy characterised by the use of allogeneic cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2854896P | 1996-10-11 | 1996-10-11 | |
| PCT/US1997/018718 WO1998016238A2 (en) | 1996-10-11 | 1997-10-10 | Cancer immunotherapy using tumor cells combined with mixed lymphocytes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9712988A true BR9712988A (pt) | 2000-10-24 |
Family
ID=21844058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9712988-7A BR9712988A (pt) | 1996-10-11 | 1997-10-10 | Imunoterapia do câncer usando células tumorais combinadas com mistura de linfócitos |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6207147B1 (enExample) |
| EP (1) | EP0930887B1 (enExample) |
| JP (1) | JP2001509135A (enExample) |
| KR (1) | KR20000049096A (enExample) |
| CN (1) | CN1237909A (enExample) |
| AR (1) | AR004445A1 (enExample) |
| AT (1) | ATE229810T1 (enExample) |
| AU (1) | AU743855B2 (enExample) |
| BR (1) | BR9712988A (enExample) |
| CA (1) | CA2267157C (enExample) |
| DE (1) | DE69718029T2 (enExample) |
| NO (1) | NO991691L (enExample) |
| WO (1) | WO1998016238A2 (enExample) |
Families Citing this family (91)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080220025A1 (en) * | 1995-03-17 | 2008-09-11 | James Thompson | Treating Tumors Using Implants Comprising Combinations of Allogeneic Cells |
| US7361332B2 (en) | 1995-03-17 | 2008-04-22 | The Regents Of The University Of California | Treating tumors using implants comprising combinations of allogeneic cells |
| AU7154598A (en) * | 1997-04-23 | 1998-11-13 | Regents Of The University Of California, The | A cell strain with activated anti-cancer cytotoxic activity |
| DE69837552D1 (de) | 1997-10-10 | 2007-05-24 | Univ California | Allogene zellkombination enthaltende implantate zur krebsbehandlung |
| WO1999019462A1 (en) * | 1997-10-10 | 1999-04-22 | The Regents Of The University Of California | Enhanced immunogenic cell populations prepared using h2 receptor antagonists |
| DE69820291D1 (de) | 1997-10-10 | 2004-01-15 | Meyer Pharmaceuticals Llc | Krebsimmuntherapie mittels allostimulierten zellen zur sequentiellen implantationsstrategie |
| JP4389039B2 (ja) * | 1998-04-09 | 2009-12-24 | 株式会社リンフォテック | アロジェニックな活性化cd4陽性細胞を主成分とする医薬組成物、およびその製造方法、ならびに該医薬組成物調製用キット |
| US7666609B1 (en) | 1998-12-01 | 2010-02-23 | Shanghai Cp Guojian Pharmaceutical Co. Ltd. | Method and composition for diagnosis of melanocytic lesions |
| EP1159967B1 (en) * | 1999-02-09 | 2008-09-10 | Riken | Tumor vaccines |
| US7303911B2 (en) | 2000-04-01 | 2007-12-04 | Onyvax Limited | Prostate cell lines |
| US6984522B2 (en) | 2000-08-03 | 2006-01-10 | Regents Of The University Of Michigan | Isolation and use of solid tumor stem cells |
| US20080194022A1 (en) * | 2000-08-03 | 2008-08-14 | Clarke Michael F | Isolation and use of solid tumor stem cells |
| US8044259B2 (en) | 2000-08-03 | 2011-10-25 | The Regents Of The University Of Michigan | Determining the capability of a test compound to affect solid tumor stem cells |
| DE10043437A1 (de) * | 2000-09-04 | 2002-03-28 | Horst Lindhofer | Verwendung von trifunktionellen bispezifischen und trispezifischen Antikörpern zur Behandlung von malignem Aszites |
| US7723111B2 (en) * | 2001-03-09 | 2010-05-25 | The United States Of America As Represented By The Department Of Health And Human Services | Activated dual specificity lymphocytes and their methods of use |
| ATE500808T1 (de) * | 2001-05-11 | 2011-03-15 | Wellstat Biologics Corp | Onkolytische virustherapie |
| US7658926B2 (en) * | 2001-09-14 | 2010-02-09 | Opexa Pharmaceuticals, Inc. | Autologous T-cell vaccines materials and methods |
| EP1293205A1 (en) * | 2001-09-18 | 2003-03-19 | G2M Cancer Drugs AG | Valproic acid and derivatives thereof for the combination therapy of human cancers, for the treatment of tumour metastasis and minimal residual disease |
| CA2469135A1 (en) * | 2001-11-27 | 2003-06-05 | Nexyte Ab | Production of eukaryotic proteins and nucleic acid molecules in c. elegans |
| KR20020060643A (ko) * | 2002-06-04 | 2002-07-18 | 김진경 | 타인의 면역시스템을 이용하는 암의 치료 방법 |
| AU2003258090B2 (en) * | 2002-08-08 | 2010-07-22 | Baylor College Of Medicine | Isolation and identification of T cells |
| US7571817B2 (en) * | 2002-11-06 | 2009-08-11 | Varco I/P, Inc. | Automatic separator or shaker with electromagnetic vibrator apparatus |
| WO2004075855A2 (en) | 2003-02-26 | 2004-09-10 | Biomed Solutions, Llc | Process for in vivo treatment of specific biological targets in bodily fluid |
| WO2004096244A1 (en) * | 2003-05-02 | 2004-11-11 | Md Bioalpha Co. Ltd. | Method of preparing tumor vaccine for the inducement of anti-tumor activity and a pharmaceutical composition containing the same |
| EP1641491B1 (en) | 2003-06-11 | 2008-01-02 | University of Chicago | Increased t-cell tumor infiltration by mutant light |
| US7811983B2 (en) * | 2003-06-11 | 2010-10-12 | The University Of Chicago | Increased T-cell tumor infiltration and eradication of metastases by mutant light |
| US20050019336A1 (en) | 2003-07-23 | 2005-01-27 | Dalgleish Angus George | Human prostate cell lines in cancer treatment |
| US7696322B2 (en) * | 2003-07-28 | 2010-04-13 | Catalent Pharma Solutions, Inc. | Fusion antibodies |
| SG146691A1 (en) * | 2003-10-08 | 2008-10-30 | Vet Stem Inc | Methods of preparing and using stem cell compositions and kits comprising the same |
| US8029454B2 (en) | 2003-11-05 | 2011-10-04 | Baxter International Inc. | High convection home hemodialysis/hemofiltration and sorbent system |
| US20050112684A1 (en) * | 2003-11-21 | 2005-05-26 | Eric Holzle | Class I and Class II MHC Profiling for Social and Sexual Matching of Human Partners |
| ES2383306T3 (es) | 2004-02-03 | 2012-06-20 | The Regents Of The University Of Michigan | Composiciones para el tratamiento del cáncer de mama y de páncreas |
| US7858323B2 (en) | 2004-06-09 | 2010-12-28 | The Regents Of The University Of Michigan | Phage microarray profiling of the humoral response to disease |
| US8257715B1 (en) | 2004-08-26 | 2012-09-04 | University Of Notre Dame | Tissue vaccines and uses thereof |
| US9155789B2 (en) * | 2005-04-25 | 2015-10-13 | New York University | Use of allogenic or syngenic major histocompatibility complex (MHC) molecules as universal adjuvants for vaccines against neoplastic disease, infection and autoimmune disease |
| US20090162405A1 (en) * | 2006-12-14 | 2009-06-25 | Yong Qian | Proteinase-engineered cancer vaccine induces immune responses to prevent cancer and to systemically kill cancer cells |
| US8778362B2 (en) | 2005-10-27 | 2014-07-15 | University Of Notre Dame | Anti-tumor/cancer heterologous acellular collagenous preparations and uses thereof |
| US8802113B2 (en) * | 2005-10-27 | 2014-08-12 | University Of Notre Dame | Extracellular matrix cancer vaccine adjuvant |
| US8778360B2 (en) * | 2005-10-27 | 2014-07-15 | University Of Notre Dame | Extracellular matrix cancer vaccine adjuvant |
| US9308252B2 (en) * | 2005-10-27 | 2016-04-12 | Cook Biotech, Inc. | Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins |
| ES2641087T3 (es) | 2005-10-31 | 2017-11-07 | Oncomed Pharmaceuticals, Inc. | Composiciones y métodos para el diagnóstico y el tratamiento del cáncer |
| WO2007053648A2 (en) * | 2005-10-31 | 2007-05-10 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| US7723477B2 (en) | 2005-10-31 | 2010-05-25 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth |
| WO2008121102A2 (en) * | 2006-02-21 | 2008-10-09 | The Regents Of The University Of Michigan | Hedgehog signaling pathway antagonist cancer treatment |
| WO2007100640A2 (en) * | 2006-02-21 | 2007-09-07 | The Regents Of The University Of Michigan | Growth hormone receptor antagonist cancer treatment |
| ES2553192T3 (es) * | 2006-05-05 | 2015-12-04 | Opexa Therapeutics | Vacuna de células T |
| ES2613957T3 (es) | 2006-08-04 | 2017-05-29 | Medimmune Limited | Anticuerpos contra ERBB2 |
| US7972594B2 (en) * | 2006-11-13 | 2011-07-05 | Immunovative Therapies Ltd. | Ablative immunotherapy |
| WO2008061392A1 (en) * | 2006-11-22 | 2008-05-29 | Hua Liu | Method for preparing cell populations with anti-tumor immune response activity |
| US20080147007A1 (en) * | 2006-12-19 | 2008-06-19 | Toby Freyman | Delivery device with pressure control |
| EP2106439B1 (en) | 2007-01-24 | 2014-11-12 | The Regents of the University of Michigan | Compositions and methods for treating and diagnosing pancreatic cancer |
| WO2008092153A2 (en) | 2007-01-26 | 2008-07-31 | University Of Louisville Research Foundation, Inc. | Modification of exosomal components for use as a vaccine |
| US20090093429A1 (en) * | 2007-02-08 | 2009-04-09 | Yang-Xin Fu | Combination therapy for treating cancer |
| EP2650018A3 (en) | 2007-05-14 | 2014-09-03 | The University of Chicago | Antibody-LIGHT fusion products for cancer therapeutics |
| CN101855549A (zh) * | 2007-09-12 | 2010-10-06 | 耶达研究及发展有限公司 | 在免疫豁免部位内治疗肿瘤的方法 |
| US8114276B2 (en) | 2007-10-24 | 2012-02-14 | Baxter International Inc. | Personal hemodialysis system |
| US9283266B2 (en) * | 2008-02-28 | 2016-03-15 | University Of Notre Dame | Metastasis inhibition preparations and methods |
| AU2009296246B2 (en) | 2008-09-26 | 2015-07-30 | Oncomed Pharmaceuticals, Inc. | Frizzled-binding agents and uses thereof |
| CA2779436A1 (en) * | 2008-10-31 | 2010-05-06 | Biogen Idec Ma Inc. | Light targeting molecules and uses thereof |
| JP5716180B2 (ja) | 2008-11-11 | 2015-05-13 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 抗cxcr1組成物および方法 |
| CU23740A1 (es) * | 2009-09-29 | 2011-12-28 | Ct Ingenieria Genetica Biotech | Método de obtención de una formulación de antígenos del virus de la hepatitis b |
| KR20120093978A (ko) * | 2009-10-27 | 2012-08-23 | 이뮤니쿰 에이비 | 항원 특이적 t 세포의 증식 방법 |
| DK2510084T3 (da) * | 2009-12-08 | 2020-04-27 | The Board Of Trustees Of The Univ Of Illionis | Stamcelleimmunmoduleringsanvendelsesfremgangsmåder og apparat |
| US8846059B2 (en) | 2009-12-08 | 2014-09-30 | University Of Notre Dame | Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer |
| US20110150934A1 (en) * | 2009-12-18 | 2011-06-23 | University Of Notre Dame | Ovarian Tumor Tissue Cell Preparations/Vaccines for the Treatment/Inhibition of Ovarian Tumors and Ovarian Cancer |
| TWI535445B (zh) | 2010-01-12 | 2016-06-01 | 安可美德藥物股份有限公司 | Wnt拮抗劑及治療和篩選方法 |
| US20110237461A1 (en) * | 2010-03-17 | 2011-09-29 | The Regents Of The University Of Michigan | Using phage epitopes to profile the immune response |
| JP2013530929A (ja) | 2010-04-01 | 2013-08-01 | オンコメッド ファーマシューティカルズ インコーポレイテッド | frizzled結合剤およびその使用 |
| WO2011129348A1 (ja) * | 2010-04-13 | 2011-10-20 | 株式会社Reiメディカル | 癌組織由来細胞塊または癌細胞凝集塊から得られる癌治療用組成物およびそれを用いた免疫療法剤の製造方法ならびに免疫療法効果評価方法 |
| KR20140099328A (ko) | 2011-05-03 | 2014-08-11 | 이뮤노베이티브 테라피스, 엘티디. | 생세포를 포함하는 생물학적 약물을 처리하기 위한 용기 또는 주사기 |
| LT3892295T (lt) * | 2011-05-24 | 2023-07-10 | BioNTech SE | Individualizuotos vakcinos nuo vėžio |
| US9493532B2 (en) | 2011-12-15 | 2016-11-15 | The University Of Chicago | Compositions for cancer therapy using mutant light molecules with increased affinity to receptors |
| US9266959B2 (en) | 2012-10-23 | 2016-02-23 | Oncomed Pharmaceuticals, Inc. | Methods of treating neuroendocrine tumors using frizzled-binding agents |
| CN105073195A (zh) | 2013-02-04 | 2015-11-18 | 昂科梅德制药有限公司 | 使用Wnt途径抑制剂进行治疗的方法及对该治疗的监测 |
| US9168300B2 (en) | 2013-03-14 | 2015-10-27 | Oncomed Pharmaceuticals, Inc. | MET-binding agents and uses thereof |
| CA2925104A1 (en) * | 2013-09-27 | 2015-04-02 | Vaccinogen International Partners, Lp | Autologous tumor vaccines and methods |
| EP3215165B1 (en) | 2014-11-05 | 2020-12-23 | Memorial Sloan Kettering Cancer Center | Methods of selecting t cell line and donor thereof for adoptive cellular therapy |
| US20180055920A1 (en) * | 2015-03-12 | 2018-03-01 | University Of Iowa Research Foundation | Vaccine, therapeutic composition and methods for treating or inhibiting cancer |
| EP3313419B1 (en) * | 2015-06-26 | 2020-08-19 | Memorial Sloan Kettering Cancer Center | Methods of treating cmv retinitis by t cell therapy |
| WO2017023803A1 (en) | 2015-07-31 | 2017-02-09 | Regents Of The University Of Minnesota | Modified cells and methods of therapy |
| CN109068658A (zh) | 2015-11-18 | 2018-12-21 | 杜克大学 | 用于治疗癌症的肿瘤浸润淋巴细胞 |
| CA3041068A1 (en) | 2016-10-18 | 2018-04-26 | Regents Of The University Of Minnesota | Tumor infiltrating lymphocytes and methods of therapy |
| US20200237904A1 (en) | 2017-01-26 | 2020-07-30 | Immune Therapeutics Inc. | Methods and Compositions Useful for Treating Cancer |
| WO2018224166A1 (en) | 2017-06-09 | 2018-12-13 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy |
| JP2020530307A (ja) | 2017-06-30 | 2020-10-22 | インティマ・バイオサイエンス,インコーポレーテッド | 遺伝子治療のためのアデノ随伴ウイルスベクター |
| KR102256337B1 (ko) * | 2017-10-17 | 2021-05-26 | (주)노터스생명과학 | 조직이식을 위한 세포배양액을 포함하는 면역억제제 |
| US11446329B2 (en) | 2017-11-01 | 2022-09-20 | Restem Llc | Natural killer cell adoptive transfer therapy for the elimination of senescent PBMCs, reduction of inflammatory cytokines and treatment of IBS |
| IL259392A (en) | 2018-05-15 | 2018-08-01 | Yeda Res & Dev | Vaccination with cancer neoantigens |
| FR3082730B1 (fr) * | 2018-06-21 | 2022-04-22 | Med Inn Pharma | Methode de resolution de l'inflammation pro-tumorale a l'aide d'une preparation pharmaceutique |
| WO2023196232A1 (en) * | 2022-04-04 | 2023-10-12 | University Of Florida Research Foundation, Inc. | Method of characterizing tumors |
| CN114984199A (zh) * | 2022-04-19 | 2022-09-02 | 苏州尔生生物医药有限公司 | 一种基于癌症特异性t细胞的细胞系统、淋巴细胞药物及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192537A (en) | 1984-03-30 | 1993-03-09 | Cellcor Inc. | Method of treating renal cell carcinoma using activated mononuclear cells, renal tumor antigen and cimetidine |
| US4828991A (en) | 1984-01-31 | 1989-05-09 | Akzo N.V. | Tumor specific monoclonal antibodies |
| JP2639835B2 (ja) * | 1988-11-30 | 1997-08-13 | 有限会社ジオリサーチ | 免疫記憶細胞懸濁液の調製方法 |
| US5229115A (en) * | 1990-07-26 | 1993-07-20 | Immunex Corporation | Adoptive immunotherapy with interleukin-7 |
| JPH06121672A (ja) * | 1992-10-13 | 1994-05-06 | Cellcor Inc | 免疫反応性細胞の製造 |
| US5820872A (en) * | 1992-11-18 | 1998-10-13 | Yale University | Methods and compositions for improving the effectiveness of X-irradiation therapy for the treatment of an internal solid tumor |
| WO1994020120A1 (en) | 1993-03-12 | 1994-09-15 | Cellcor, Inc. | In vitro assay measuring degree of activation of immune cells |
| CA2178950A1 (en) | 1993-12-14 | 1995-06-22 | Yajun Guo | Tumor cell fusions and methods for use of such tumor cell fusions |
| US5759535A (en) | 1994-05-13 | 1998-06-02 | Research Corporation Technologies, Inc. | Immunotherapeutic strategies for the treatment of cancer |
| CA2192655A1 (en) * | 1994-06-14 | 1995-12-21 | Edgar G. Engleman | Methods for in vivo t cell activation by antigen-pulsed dendritic cells |
| DE4431401A1 (de) | 1994-08-24 | 1996-02-29 | Max Delbrueck Centrum | Lebendvakzine gegen Tumorerkrankungen |
| BR9607894A (pt) * | 1995-03-17 | 1999-06-01 | Univ California | Processo para tratar tumores |
| US6277368B1 (en) * | 1996-07-25 | 2001-08-21 | The Regents Of The University Of California | Cancer immunotherapy using autologous tumor cells combined with cells expressing a membrane cytokine |
-
1997
- 1997-10-10 AU AU48242/97A patent/AU743855B2/en not_active Ceased
- 1997-10-10 WO PCT/US1997/018718 patent/WO1998016238A2/en not_active Ceased
- 1997-10-10 CN CN97199908A patent/CN1237909A/zh active Pending
- 1997-10-10 JP JP51780398A patent/JP2001509135A/ja not_active Ceased
- 1997-10-10 CA CA002267157A patent/CA2267157C/en not_active Expired - Fee Related
- 1997-10-10 BR BR9712988-7A patent/BR9712988A/pt not_active Application Discontinuation
- 1997-10-10 EP EP97910999A patent/EP0930887B1/en not_active Expired - Lifetime
- 1997-10-10 DE DE69718029T patent/DE69718029T2/de not_active Expired - Lifetime
- 1997-10-10 KR KR1019990703176A patent/KR20000049096A/ko not_active Withdrawn
- 1997-10-10 US US08/948,939 patent/US6207147B1/en not_active Expired - Lifetime
- 1997-10-10 AT AT97910999T patent/ATE229810T1/de not_active IP Right Cessation
- 1997-10-13 AR ARP970104701A patent/AR004445A1/es not_active Application Discontinuation
-
1999
- 1999-04-09 NO NO991691A patent/NO991691L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998016238A3 (en) | 1998-09-11 |
| CA2267157A1 (en) | 1998-04-23 |
| AU743855B2 (en) | 2002-02-07 |
| CN1237909A (zh) | 1999-12-08 |
| DE69718029T2 (de) | 2003-10-16 |
| DE69718029D1 (de) | 2003-01-30 |
| US6207147B1 (en) | 2001-03-27 |
| ATE229810T1 (de) | 2003-01-15 |
| NO991691L (no) | 1999-06-09 |
| AU4824297A (en) | 1998-05-11 |
| EP0930887B1 (en) | 2002-12-18 |
| NO991691D0 (no) | 1999-04-09 |
| EP0930887A2 (en) | 1999-07-28 |
| AR004445A1 (es) | 1998-12-16 |
| JP2001509135A (ja) | 2001-07-10 |
| WO1998016238A2 (en) | 1998-04-23 |
| CA2267157C (en) | 2005-05-31 |
| KR20000049096A (ko) | 2000-07-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9712988A (pt) | Imunoterapia do câncer usando células tumorais combinadas com mistura de linfócitos | |
| Marshall et al. | Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti–carcinoembryonic antigen immune responses | |
| Hui et al. | Phase I study of immunotherapy of cutaneous metastases of human carcinoma using allogeneic and xenogeneic MHC DNA–liposome complexes | |
| ES2826480T3 (es) | Métodos para predecir la utilidad de neoantígenos para inmunoterapia | |
| TR200100936T2 (tr) | Terapötik aşılama | |
| BR0113491A (pt) | Polinucleotìdeo e polipeptìdeo isolados, vetor de expressão, célula hospedeira, proteìna de fusão, métodos para estimular e/ou expandir células t especìficas para uma protéina de tumor, para estimular uma resposta imune em um paciente, para o tratamento de um câncer em um paciente e para inibir o desenvolvimento de um câncer em um paciente, população de célula t isolada, composição, e, uso de um componente. | |
| CA2203991A1 (en) | Methods and devices for immunizing a host to tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides | |
| DE69839273D1 (de) | Krebs immuntherapie mit semi-allogenen zellen | |
| BR0112542A (pt) | Composições e métodos papa a terapia e a diagnose de câncer ovariano | |
| Lynch et al. | In vivo evaluation of the effects of interleukins 2, 4 and 7 on enhancing the immunotherapeutic efficacy of anti‐tumor cytotoxic T lymphocytes | |
| DK1225870T3 (da) | Sammensætning og fremgangsmåde til cancerantigenimmunterapi | |
| Triozzi et al. | Phase I study of a plasmid DNA vaccine encoding MART-1 in patients with resected melanoma at risk for relapse | |
| BR0308101A (pt) | Vacinas de dna que codificam cea e um ligante de cd40 e seus métodos de uso | |
| NZ505834A (en) | Compositions containing polypeptides isolated from mycobacterium vaccae and methods for their use | |
| Morton et al. | Active specific immunotherapy in malignant melanoma | |
| Hage et al. | TAP expression level in tumor cells defines the nature and processing of MHC class I peptides for recognition by tumor‐specific cytotoxic T lymphocytes | |
| Garaci | Thymosin α1: a historical overview | |
| Correale et al. | Tumour-associated antigen (TAA)-specific cytotoxic T cell (CTL) response in vitro and in a mouse model, induced by TAA-plasmids delivered by influenza virosomes | |
| Mellstedt et al. | Ga733/EpCAM as a target for passive and active specific immunotherapy in patients with colorectal carcinoma | |
| Mulé | Dendritic cell‐based vaccines for pancreatic cancer and melanoma | |
| Basak et al. | Colorectal cancer vaccines: antiidiotypic antibody, recombinant protein, and viral vector | |
| CA2254082A1 (en) | Metastatic colorectal cancer vaccine | |
| US20100092499A1 (en) | Alpha Thymosin Peptides as Cancer Vaccine Adjuvants | |
| NO930798L (no) | Fremgangsmaate og middel mot tumorer | |
| DE60130634D1 (de) | Identifizierung von antigenen peptiden durch zytotoxische t-lymphozyten aktiviert von dendritischen zellhybriden |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Ipc: A61K 35/17 (2015.01), A61K 35/13 (2015.0 |