BR9610013A - Processos para reconstituir um embrião animal e para preparar um animal, embrião de animal reconstituído, e , animal - Google Patents
Processos para reconstituir um embrião animal e para preparar um animal, embrião de animal reconstituído, e , animalInfo
- Publication number
- BR9610013A BR9610013A BR9610013-3A BR9610013A BR9610013A BR 9610013 A BR9610013 A BR 9610013A BR 9610013 A BR9610013 A BR 9610013A BR 9610013 A BR9610013 A BR 9610013A
- Authority
- BR
- Brazil
- Prior art keywords
- animal
- embryo
- reconstituted
- time
- activated
- Prior art date
Links
- 241001465754 Metazoa Species 0.000 title abstract 10
- 210000001161 mammalian embryo Anatomy 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 3
- 210000000287 oocyte Anatomy 0.000 abstract 2
- 230000009261 transgenic effect Effects 0.000 abstract 2
- 230000035519 G0 Phase Effects 0.000 abstract 1
- 230000010190 G1 phase Effects 0.000 abstract 1
- 229940122255 Microtubule inhibitor Drugs 0.000 abstract 1
- KYRVNWMVYQXFEU-UHFFFAOYSA-N Nocodazole Chemical compound C1=C2NC(NC(=O)OC)=NC2=CC=C1C(=O)C1=CC=CS1 KYRVNWMVYQXFEU-UHFFFAOYSA-N 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000022131 cell cycle Effects 0.000 abstract 1
- 210000000805 cytoplasm Anatomy 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 230000031864 metaphase Effects 0.000 abstract 1
- 231100000782 microtubule inhibitor Toxicity 0.000 abstract 1
- 229950006344 nocodazole Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
- C12N15/877—Techniques for producing new mammalian cloned embryos
- C12N15/8773—Ovine embryos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
- C12N15/877—Techniques for producing new mammalian cloned embryos
- C12N15/8771—Bovine embryos
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Developmental Biology & Embryology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Reproductive Health (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Gynecology & Obstetrics (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Environmental Sciences (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Husbandry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9517779.6A GB9517779D0 (en) | 1995-08-31 | 1995-08-31 | Biological manipulation |
| PCT/GB1996/002098 WO1997007668A1 (en) | 1995-08-31 | 1996-08-30 | Unactivated oocytes as cytoplast recipients for nuclear transfer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9610013A true BR9610013A (pt) | 1999-12-21 |
Family
ID=10779997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9610013-3A BR9610013A (pt) | 1995-08-31 | 1996-08-30 | Processos para reconstituir um embrião animal e para preparar um animal, embrião de animal reconstituído, e , animal |
Country Status (22)
| Country | Link |
|---|---|
| US (12) | US6252133B1 (enExample) |
| EP (1) | EP0847237B1 (enExample) |
| JP (3) | JP2000506721A (enExample) |
| KR (4) | KR100533477B1 (enExample) |
| CN (3) | CN1250715C (enExample) |
| AT (1) | ATE400176T1 (enExample) |
| AU (1) | AU728809B2 (enExample) |
| BR (1) | BR9610013A (enExample) |
| CA (1) | CA2229657A1 (enExample) |
| CZ (1) | CZ60498A3 (enExample) |
| DE (1) | DE69637591D1 (enExample) |
| DK (1) | DK0847237T3 (enExample) |
| ES (1) | ES2309989T3 (enExample) |
| GB (1) | GB9517779D0 (enExample) |
| HU (1) | HUP9802485A3 (enExample) |
| IL (1) | IL123417A0 (enExample) |
| NO (1) | NO980846L (enExample) |
| NZ (2) | NZ316148A (enExample) |
| PL (1) | PL325336A1 (enExample) |
| SG (1) | SG75919A1 (enExample) |
| WO (1) | WO1997007668A1 (enExample) |
| ZA (1) | ZA967383B (enExample) |
Families Citing this family (192)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5480772A (en) | 1993-02-03 | 1996-01-02 | Brandeis University | In vitro activation of a nucleus |
| GB9517780D0 (en) * | 1995-08-31 | 1995-11-01 | Roslin Inst Edinburgh | Biological manipulation |
| GB9517779D0 (en) * | 1995-08-31 | 1995-11-01 | Roslin Inst Edinburgh | Biological manipulation |
| US7304204B2 (en) | 1995-08-31 | 2007-12-04 | Roslin Institute | Ungulates produced by nuclear transfer of G1 cells |
| US6025155A (en) * | 1996-04-10 | 2000-02-15 | Chromos Molecular Systems, Inc. | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| US6077697A (en) * | 1996-04-10 | 2000-06-20 | Chromos Molecular Systems, Inc. | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| EP0941310A1 (en) | 1996-10-11 | 1999-09-15 | THE TEXAS A&M UNIVERSITY SYSTEM | Methods for the generation of primordial germ cells and transgenic animal species |
| US6235969B1 (en) * | 1997-01-10 | 2001-05-22 | University Of Massachusetts | Cloning pigs using donor nuclei from non-quiescent differentiated cells |
| US5945577A (en) * | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
| US20090092588A1 (en) * | 1997-01-10 | 2009-04-09 | University Of Massachusetts As Represented By Its Amherst Campus | Cloned ungulate embryos and animals, use of cells, tissues and organs thereof for transplantation therapies including parkinson's disease |
| US6011197A (en) | 1997-03-06 | 2000-01-04 | Infigen, Inc. | Method of cloning bovines using reprogrammed non-embryonic bovine cells |
| ES2513043T3 (es) | 1997-03-26 | 2014-10-24 | Imperial Innovations Limited | Proteína de fusión anticoagulante anclada a membrana de la célula |
| IL133786A0 (en) | 1997-07-03 | 2001-04-30 | Univ Massachusetts | Cloning using donor nuclei from non-serum starved, differentiated cells |
| US7923216B2 (en) | 1997-08-14 | 2011-04-12 | Institut Pasteur | In vivo modulation of neuronal transport |
| US7923015B2 (en) | 1997-08-14 | 2011-04-12 | Institut Pasteur | Methods for direct visualization of active synapses |
| JPH11127852A (ja) * | 1997-10-28 | 1999-05-18 | Snow Brand Milk Prod Co Ltd | 上皮細胞のg0期同調方法 |
| AU739902B2 (en) * | 1998-01-16 | 2001-10-25 | Agrobiogen Gmbh | Efficient nuclear transfer using fetal fibroblasts |
| US7351876B2 (en) | 1998-01-16 | 2008-04-01 | Agrobiogen Gmbh Biotechnologie | Efficient nuclear transfer with primordial gametes |
| CA2318117A1 (en) * | 1998-01-16 | 1999-07-22 | Agrobiogen Gmbh | Efficient nuclear transfer using primordial germ cells |
| US6331659B1 (en) * | 1998-01-21 | 2001-12-18 | University Of Hawaii | Cumulus cells as nuclear donors |
| JP2002511234A (ja) * | 1998-03-16 | 2002-04-16 | リレグ ピーティーワイ リミテッド | ブタの核移植 |
| AUPP294898A0 (en) * | 1998-04-15 | 1998-05-07 | Monash University | Method of nuclear transfer |
| GB9808325D0 (en) * | 1998-04-20 | 1998-06-17 | Ltr Ciz Di Associazione Italia | Source of nuclei for nuclear transfer |
| US6143564A (en) * | 1998-07-07 | 2000-11-07 | University Of Hawaii | Use of the polar body chromosomes for the production of embryos and normal offspring |
| GB9820988D0 (en) * | 1998-09-25 | 1998-11-18 | Biotech & Biolog Scien Res | Screening method |
| GB2365445A (en) * | 1998-10-12 | 2002-02-20 | Geron Bio Med Ltd | Porcine occcytes with improved developmental competence |
| EP1818397A1 (en) * | 1998-11-02 | 2007-08-15 | Trustees Of Tufts College | Methods for cloning animals |
| US6781030B1 (en) | 1998-11-02 | 2004-08-24 | Trustee Of Tufts College, Ballou Hall | Methods for cloning mammals using telophase oocytes |
| ATE427653T1 (de) | 1998-11-19 | 2009-04-15 | Pharming Intellectual Pty Bv | Stabilisierung der milch transgener tieren |
| US6700037B2 (en) | 1998-11-24 | 2004-03-02 | Infigen, Inc. | Method of cloning porcine animals |
| US6258998B1 (en) | 1998-11-24 | 2001-07-10 | Infigen, Inc. | Method of cloning porcine animals |
| CA2360549C (en) * | 1999-01-13 | 2013-04-09 | Ppl Therapeutics (Scotland) Limited | Double nuclear transfer method and results thereof |
| US7531715B1 (en) * | 1999-01-13 | 2009-05-12 | Ppl Therapeutics (Scotland) | Double nuclear transfer method and results thereof |
| WO2000044914A1 (en) | 1999-01-28 | 2000-08-03 | Medical College Of Georgia Research Institute, Inc. | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna |
| EP1179000A4 (en) | 1999-02-26 | 2005-10-12 | Millennium Pharm Inc | DECISION PROTEINS AND THEIR USE |
| US20020012660A1 (en) * | 1999-03-04 | 2002-01-31 | Alan Colman | Method of preparing a somatic cells for nuclear transfer |
| AU780754B2 (en) * | 1999-03-04 | 2005-04-14 | Revivicor Inc | Genetic modification of somatic cells and uses thereof |
| WO2001000855A1 (en) | 1999-06-23 | 2001-01-04 | Ppl Therapeutics (Scotland) Ltd. | Fusion proteins incorporating lysozyme |
| KR100368435B1 (ko) * | 1999-06-30 | 2003-01-24 | 황우석 | 체세포 복제동물의 생산을 위한 세포융합방법 |
| WO2001000794A1 (en) * | 1999-06-30 | 2001-01-04 | Hwang, Woo-Suk | Method for producing cloned tigers by employing inter-species nuclear transplantation technique |
| JP2003503044A (ja) * | 1999-06-30 | 2003-01-28 | ワン,ウー−サク | 種間核移植技術を用いたヒトクローン胚の作製方法 |
| US6590139B1 (en) | 1999-06-30 | 2003-07-08 | Woo-Suk Hwang | Method for producing cloned cows |
| KR100414043B1 (ko) * | 1999-06-30 | 2004-01-13 | 황우석 | 체세포 복제동물 및 그 생산방법 |
| US7291714B1 (en) | 1999-06-30 | 2007-11-06 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
| EP1210428B1 (en) | 1999-08-23 | 2015-03-18 | Dana-Farber Cancer Institute, Inc. | Pd-1, a receptor for b7-4, and uses therefor |
| EP2275559A3 (en) | 1999-09-28 | 2011-03-23 | Shire Human Genetic Therapies, Inc. | Optimized messenger RNA |
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| GB9927444D0 (en) * | 1999-11-19 | 2000-01-19 | Cancer Res Campaign Tech | Inhibiting gene expression |
| KR100417566B1 (ko) * | 1999-11-19 | 2004-02-05 | 한국생명공학연구원 | 체세포 핵치환 복제수정란의 대량생산방법 |
| US7074983B2 (en) * | 1999-11-19 | 2006-07-11 | Kirin Beer Kabushiki Kaisha | Transgenic bovine comprising human immunoglobulin loci and producing human immunoglobulin |
| US7820878B2 (en) * | 1999-11-19 | 2010-10-26 | Kyowa Hakko Kirin Co., Ltd. | Production of ungulates, preferably bovines that produce human immunoglobulins |
| US7414170B2 (en) * | 1999-11-19 | 2008-08-19 | Kirin Beer Kabushiki Kaisha | Transgenic bovines capable of human antibody production |
| AU1777301A (en) * | 1999-11-19 | 2001-05-30 | Hematech, Llc | Production of ungulates, preferably bovines that produce human immunoglobulins |
| US7071372B2 (en) | 2000-01-04 | 2006-07-04 | University Of Connecticut | Method for cloning animals with targetted genetic alterations by transfer of long-term cultured male or female somatic cell nuclei, comprising artificially-induced genetic alterations, to enucleated recipient cells |
| US6635802B1 (en) * | 2000-01-10 | 2003-10-21 | The Texas A&M University System | Nuclear transfer using cells cultured in serum starvation media containing apoptosis inhibitors |
| EP1248640B1 (en) | 2000-01-20 | 2006-10-04 | Diabcell Pty Limited | Preparation and xenotransplantation of porcine islets |
| AU2001236919A1 (en) * | 2000-02-09 | 2001-08-20 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Premeiotic and postmeiotic origin of teratomas: isolated teratoma stem cells for therapeutic uses |
| CA2403344C (en) | 2000-03-15 | 2013-05-21 | The University Of Georgia Research Foundation, Inc. | Effective nuclear reprogramming in mammals |
| GB2360522A (en) | 2000-03-24 | 2001-09-26 | Geron Corp | A strategy for maintaining pregnancy |
| WO2001088096A2 (en) * | 2000-05-15 | 2001-11-22 | Geron Corporation | Ovine tissue for xenotransplantation |
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| WO2002014473A2 (en) | 2000-08-15 | 2002-02-21 | Board Of Trustees Of The University Of Illinois | Animals expressing exogenous igf-i in their milk |
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| EP1900815B1 (en) | 2001-07-12 | 2016-09-07 | University of Massachusetts | In vivo production of small interfering RNAs that mediate gene silencing |
| ES2566561T3 (es) | 2001-07-12 | 2016-04-13 | University Of Massachusetts | Producción in vivo de ARN pequeños de interferencia que median el silenciamiento génico |
| US20030211603A1 (en) * | 2001-08-14 | 2003-11-13 | Earp David J. | Reprogramming cells for enhanced differentiation capacity using pluripotent stem cells |
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| US7704736B2 (en) * | 2001-11-09 | 2010-04-27 | Trustees Of The University Of Pennsylvania | Compositions for the derivation of germ cells from stem cells and methods of use thereof |
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| US7208306B2 (en) | 2002-10-24 | 2007-04-24 | Wyeth | Compositions employing a novel human protein phosphatase |
| AU2003290689A1 (en) | 2002-11-08 | 2004-06-03 | Kyowa Hakko Kirin Co., Ltd. | Transgenic ungulates having reduced prion protein activity and uses thereof |
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