BR9609714A - Processo para a produção de sal de cálcio do ácido [r-(r*,r*)] - 2 - (4-flúor-fenil) - beta, gama - di - hidróxi - 5 -(1-metil-etil) - 3 - fenil - 4 -[(fenil-amino)cabornil] - 1h - pirrol - 1 - heptanóico amorfo (2:1) - Google Patents

Processo para a produção de sal de cálcio do ácido [r-(r*,r*)] - 2 - (4-flúor-fenil) - beta, gama - di - hidróxi - 5 -(1-metil-etil) - 3 - fenil - 4 -[(fenil-amino)cabornil] - 1h - pirrol - 1 - heptanóico amorfo (2:1)

Info

Publication number
BR9609714A
BR9609714A BR9609714A BR9609714A BR9609714A BR 9609714 A BR9609714 A BR 9609714A BR 9609714 A BR9609714 A BR 9609714A BR 9609714 A BR9609714 A BR 9609714A BR 9609714 A BR9609714 A BR 9609714A
Authority
BR
Brazil
Prior art keywords
phenyl
cabornyl
heptanoic
pyrrole
fluoro
Prior art date
Application number
BR9609714A
Other languages
English (en)
Portuguese (pt)
Inventor
Dieter Schweiss
Min Lin
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21696097&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9609714(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of BR9609714A publication Critical patent/BR9609714A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
BR9609714A 1995-07-17 1996-07-16 Processo para a produção de sal de cálcio do ácido [r-(r*,r*)] - 2 - (4-flúor-fenil) - beta, gama - di - hidróxi - 5 -(1-metil-etil) - 3 - fenil - 4 -[(fenil-amino)cabornil] - 1h - pirrol - 1 - heptanóico amorfo (2:1) BR9609714A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US145395P 1995-07-17 1995-07-17
PCT/US1996/011807 WO1997003960A1 (en) 1995-07-17 1996-07-16 NOVEL PROCESS FOR THE PRODUCTION OF AMORPHOUS [R-(R*,R*)]-2-(4-FLUOROPHENYL)-β,δ-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1-HEPTANOIC ACID CALCIUM SALT (2:1)

Publications (1)

Publication Number Publication Date
BR9609714A true BR9609714A (pt) 1999-02-23

Family

ID=21696097

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9609714A BR9609714A (pt) 1995-07-17 1996-07-16 Processo para a produção de sal de cálcio do ácido [r-(r*,r*)] - 2 - (4-flúor-fenil) - beta, gama - di - hidróxi - 5 -(1-metil-etil) - 3 - fenil - 4 -[(fenil-amino)cabornil] - 1h - pirrol - 1 - heptanóico amorfo (2:1)

Country Status (37)

Country Link
US (1) US6274740B1 (enExample)
EP (1) EP0839132B1 (enExample)
JP (1) JP4064459B2 (enExample)
KR (1) KR100400805B1 (enExample)
CN (1) CN1087289C (enExample)
AR (1) AR002849A1 (enExample)
AT (1) ATE199542T1 (enExample)
AU (1) AU700794B2 (enExample)
BG (1) BG63631B1 (enExample)
BR (1) BR9609714A (enExample)
CA (1) CA2220455C (enExample)
CO (1) CO4700441A1 (enExample)
CZ (1) CZ289421B6 (enExample)
DE (1) DE69611999T2 (enExample)
DK (1) DK0839132T5 (enExample)
EA (1) EA000625B1 (enExample)
EE (1) EE03605B1 (enExample)
ES (1) ES2156997T3 (enExample)
GE (1) GEP20002027B (enExample)
GR (1) GR3035859T3 (enExample)
HR (1) HRP960312B1 (enExample)
HU (1) HU220343B (enExample)
IL (1) IL122161A (enExample)
IN (1) IN185276B (enExample)
MX (1) MX9708959A (enExample)
NO (1) NO309322B1 (enExample)
NZ (1) NZ313008A (enExample)
PE (1) PE1698A1 (enExample)
PL (1) PL191017B1 (enExample)
PT (1) PT839132E (enExample)
RO (1) RO120069B1 (enExample)
SI (1) SI0839132T1 (enExample)
SK (1) SK283204B6 (enExample)
UA (1) UA50743C2 (enExample)
UY (1) UY24286A1 (enExample)
WO (1) WO1997003960A1 (enExample)
ZA (1) ZA966043B (enExample)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI94339C (fi) 1989-07-21 1995-08-25 Warner Lambert Co Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
IN191236B (enExample) * 1999-05-25 2003-10-11 Ranbaxy Lab Ltd
US6646133B1 (en) 2000-10-17 2003-11-11 Egis Gyogyszergyar Rt. Process for the preparation of amorphous atorvastatin calcium
HU226640B1 (en) * 1999-10-18 2009-05-28 Egis Gyogyszergyar Nyilvanosan Process for producing amorphous atorvastatin calcium salt
US7411075B1 (en) 2000-11-16 2008-08-12 Teva Pharmaceutical Industries Ltd. Polymorphic form of atorvastatin calcium
SI20425A (sl) * 1999-12-10 2001-06-30 LEK tovarna farmacevtskih in kemi�nih izdelkov d.d. Priprava amorfnega atorvastatina
IL155890A0 (en) * 2000-11-16 2003-12-23 Teva Pharma HYDROLYSIS OF [R(R*,R*)]-2-(4-FLUOROPHENYL)-beta,delta-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1-HEPTANOIC ACID ESTERS WITH CALCIUM HYDROXIDE
US7501450B2 (en) * 2000-11-30 2009-03-10 Teva Pharaceutical Industries Ltd. Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
IL156055A0 (en) 2000-11-30 2003-12-23 Teva Pharma Novel crystal forms of atorvastatin hemi calcium and processes for their preparation as well as novel processes for preparing other forms
ES2319870T3 (es) 2000-12-27 2009-05-14 Teva Pharmaceutical Industries Limited Formas cristalinas de atorvastatina.
WO2002057228A1 (en) * 2001-01-17 2002-07-25 Biocon India Limited Atorvastatin calcium
WO2002057229A1 (en) 2001-01-19 2002-07-25 Biocon India Limited FORM V CRYSTALLINE [R-(R*,R*)]-2-(4-FLUOROPHENYL)-ß,$G(D)-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1- HEPTANOIC ACID HEMI CALCIUM SALT. (ATORVASTATIN)
SI20814A (sl) 2001-01-23 2002-08-31 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Priprava amorfnega atorvastatina
SI20848A (sl) * 2001-03-14 2002-10-31 Lek, Tovarna Farmacevtskih In Kemijskih Izdelkov, D.D. Farmacevtska formulacija, ki vsebuje atorvastatin kalcij
IN190564B (enExample) * 2001-04-11 2003-08-09 Cadila Heathcare Ltd
HUP0400381A2 (hu) 2001-06-29 2004-09-28 Warner-Lambert Company Llc [R-(R*,R*)]-2-(4fluorfenil)-béta, delta-dihidroxi-5-(1-metiletil)-3-fenil-4-[(fenilamino)karbonil]-1H-pirrol-1-heptánsav 2:1 arányú kalciumsójának (atorvasztatin) kristályos formái
US7361772B2 (en) 2001-08-16 2008-04-22 Biocon Limited Process for the production of atorvastatin calcium
AU2001284385A1 (en) 2001-08-31 2003-03-10 Morepen Laboratories Ltd. An improved process for the preparation of amorphous atorvastatin calcium salt (2:1)
UA77990C2 (en) * 2001-12-12 2007-02-15 Crystalline calcium salt of (2:1) [r-(r*,r*)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrroleheptanic acid
CZ296967B6 (cs) 2002-02-01 2006-08-16 Zentiva, A.S. Zpusob výroby amorfní formy hemivápenaté soli (3R,5R) 7-[3-fenyl-4-fenylkarbamoyl-2-(4-fluorfenyl)-5-isopropylpyrrol-1-yl]-3,5-dihydroxyheptanové kyseliny (atorvastatinu)
RU2309141C2 (ru) * 2002-03-18 2007-10-27 Байокон Лимитид АМОРФНЫЕ ИНГИБИТОРЫ ГМГ-КоА-РЕДУКТАЗЫ И СПОСОБ ИХ ПОЛУЧЕНИЯ
JP4308021B2 (ja) 2002-03-18 2009-08-05 バイオコン・リミテッド 望ましい粒子サイズのアモルファスＨＭＧ−ＣｏＡレダクターゼ阻害剤
ITMI20020907A1 (it) * 2002-04-29 2003-10-29 Chemi Spa Processo di preparazione della forma amorfa del sale di calcio della atorvastatina
AU2002356423A1 (en) * 2002-05-28 2003-12-12 Cadila Healthcare Limited Process for the preparation of amorphous atorvastatin calcium
US7179942B2 (en) 2002-07-05 2007-02-20 Bicon Limited Halo-substituted active methylene compounds
AU2002330735A1 (en) * 2002-09-03 2004-03-29 Morepen Laboratories Limited Atorvastatin calcium form vi or hydrates thereof
EA013500B1 (ru) * 2003-04-11 2010-06-30 Лек Фармасьютиклз Д.Д. Способ получения аморфной кальциевой соли аторвастатина
US7232920B2 (en) 2003-04-22 2007-06-19 Biocon Process for stereoselective reduction of β-ketoesters
US7790197B2 (en) * 2003-06-09 2010-09-07 Warner-Lambert Company Llc Pharmaceutical compositions of atorvastatin
US20040253305A1 (en) * 2003-06-12 2004-12-16 Luner Paul E. Pharmaceutical compositions of atorvastatin
US20050271717A1 (en) * 2003-06-12 2005-12-08 Alfred Berchielli Pharmaceutical compositions of atorvastatin
US7655692B2 (en) * 2003-06-12 2010-02-02 Pfizer Inc. Process for forming amorphous atorvastatin
AU2003272080A1 (en) 2003-09-18 2005-04-06 Biocon Limited Novel process for the preparation of tert-butyl 6-cyano-5-hydroxy-3-oxohexanoate
CA2456430A1 (en) * 2004-01-28 2005-07-28 Brantford Chemicals Inc. Improved process for the preparation of amorphous atorvastatin calcium
CZ298382B6 (cs) * 2004-03-10 2007-09-12 Zentiva, A. S. Zpusob prípravy amorfní formy hemivápenaté soli atorvastatinu a její stabilizace
CA2666359A1 (en) 2004-03-17 2005-10-06 Yatendra Kumar Process for the production of atorvastatin calcium in amorphous form
US7875731B2 (en) 2004-05-05 2011-01-25 Pfizer Inc. Salt forms of [R-(R*,R*)]-2-(4-fluorophenyl)-β, δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)Carbonyl]-1H-pyrrole-1-heptanoic acid
AU2005263550C1 (en) * 2004-07-16 2013-01-17 Lek Pharmaceuticals D.D. Oxidative degradation products of atorvastatin calcium
WO2006021969A1 (en) 2004-08-27 2006-03-02 Biocon Limited Process for atorvastatin calcium amorphous
KR20070106680A (ko) * 2004-09-30 2007-11-05 닥터 레디스 레보러터리즈 리미티드 비정질 아토르바스타틴 칼슘
CA2582087A1 (en) * 2004-10-18 2006-04-27 Teva Pharmaceutical Industries Ltd. Process for preparing amorphous atorvastatin hemi-calcium by dissolving the salt in an organic solvent which is a mixture of an alcohol and a ketone and/or an ester and removing the solvent
EP1807055A1 (en) * 2004-10-28 2007-07-18 Warner-Lambert Company LLC Process for forming amorphous atorvastatin
AU2005305460B2 (en) 2004-11-22 2011-04-21 Dexcel Pharma Technologies Ltd. Stable atorvastatin formulations
JP2008521878A (ja) * 2004-12-02 2008-06-26 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー 非晶質アトルバスタチンの医薬組成物及びその製造のための方法
US20080108664A1 (en) 2005-12-23 2008-05-08 Liu Belle B Solid-state form of AMG 706 and pharmaceutical compositions thereof
EP1810667A1 (en) 2006-01-20 2007-07-25 KRKA, tovarna zdravil, d.d., Novo mesto Pharmaceutical composition comprising amorphous atorvastatin
JP2007231018A (ja) * 2006-03-01 2007-09-13 Teva Pharmaceutical Industries Ltd アトルバスタチンヘミカルシウムの結晶形の調製方法
US20100113802A1 (en) * 2006-11-02 2010-05-06 Cadila Pharmaceuticals Limited Process for preparing amorphous atorvastatin hemi calcium salt and its itermediate
US7834195B2 (en) 2007-01-24 2010-11-16 Apotex Pharmachem Inc. Atorvastatin calcium propylene glycol solvates
EP2185527A2 (en) * 2007-07-11 2010-05-19 Actavis Group PTC EHF Novel polymorph of atorvastatin calcium and use thereof for the preparation of amorphous atorvastatin calcium
US20090124817A1 (en) * 2007-11-09 2009-05-14 The Industry & Academic Cooperation In Chungnam National University Process for Preparing Amorphous Atorvastatin Calcium Nanoparticles
EP2075246A1 (en) 2007-12-27 2009-07-01 M. J. Institute of Research A process for preparation of amorphous form of atorvastatin hemi-calcium salt
WO2010066846A2 (en) * 2008-12-11 2010-06-17 Dsm Ip Assets B.V. Method for the isolation of atorvastatin
EP2327682A1 (en) 2009-10-29 2011-06-01 KRKA, D.D., Novo Mesto Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates
SI2373609T1 (sl) 2008-12-19 2013-12-31 Krka, D.D., Novo Mesto Uporaba amfifilnih spojin za kontrolirano kristalizacijo statinov in intermediatov statinov
CZ201039A3 (cs) 2010-01-19 2011-07-27 Zentiva, K. S Zpusob prumyslové výroby amorfní formy hemivápenaté soli (3R,5R) 7-[3-fenyl-4-fenylkarbamoyl-2-(4-fluorfenyl)-5-isopropylpyrrol-1-yl]-3,5-dihydroxyheptanové kyseliny (atorvastatinu) s vysokým specifickým povrchem a jeho použití v lékové forme

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4681893A (en) * 1986-05-30 1987-07-21 Warner-Lambert Company Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
US5216174A (en) 1988-02-22 1993-06-01 Warner-Lambert Co. Process for trans-6-[12-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
US5003080A (en) * 1988-02-22 1991-03-26 Warner-Lambert Company Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis
US5124482A (en) 1988-02-22 1992-06-23 Warner-Lambert Company Process for trans-6-(2-substituted-pyrrol-1-yl)alkyl)pyran-2-one inhibitors of cholesterol synthesis
US5245047A (en) 1988-02-22 1993-09-14 Warner-Lambert Company Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
US5149837A (en) 1988-02-22 1992-09-22 Warner-Lambert Company Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
US5097045A (en) 1989-02-01 1992-03-17 Warner-Lambert Company Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
FI94339C (fi) * 1989-07-21 1995-08-25 Warner Lambert Co Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
US5248793A (en) 1990-10-17 1993-09-28 Warner-Lambert Company Process for the synthesis of (4R-cis)-1,1-dimethylethyl 6-iodomethyl or 6-(phenyl-substituted)sulfonyloxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate
US5103024A (en) 1990-10-17 1992-04-07 Warner-Lambert Company Process for the synthesis of (4r-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
US5155251A (en) 1991-10-11 1992-10-13 Warner-Lambert Company Process for the synthesis of (5R)-1,1-dimethylethyl-6-cyano-5-hydroxy-3-oxo-hexanoate
US5298627A (en) 1993-03-03 1994-03-29 Warner-Lambert Company Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
SI1148049T1 (en) 1995-07-17 2005-02-28 Warner-Lambert Company Crystalline R-(R*,R*)$-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4- (phenylamino)carbonyl -1H-pyrrole-1-heptanoic acid hemi calcium salt (atorvastatin)

Also Published As

Publication number Publication date
PL191017B1 (pl) 2006-03-31
KR19990029045A (ko) 1999-04-15
UA50743C2 (uk) 2002-11-15
DK0839132T5 (da) 2006-03-20
IL122161A0 (en) 1998-04-05
AR002849A1 (es) 1998-04-29
HUP9903017A3 (en) 2001-01-29
MX9708959A (es) 1998-03-31
SK5898A3 (en) 1998-08-05
JP4064459B2 (ja) 2008-03-19
EE03605B1 (et) 2002-02-15
DE69611999T2 (de) 2001-07-26
HRP960312B1 (en) 2001-10-31
EA199800128A1 (ru) 1998-08-27
NO980209D0 (no) 1998-01-16
RO120069B1 (ro) 2005-08-30
ES2156997T3 (es) 2001-08-01
ATE199542T1 (de) 2001-03-15
NZ313008A (en) 2000-01-28
CN1087289C (zh) 2002-07-10
CZ12298A3 (cs) 1998-12-16
PE1698A1 (es) 1998-02-19
EA000625B1 (ru) 1999-12-29
UY24286A1 (es) 1997-01-17
IL122161A (en) 1999-07-14
IN185276B (enExample) 2000-12-16
CO4700441A1 (es) 1998-12-29
NO980209L (no) 1998-01-16
WO1997003960A1 (en) 1997-02-06
EE9700369A (et) 1998-06-15
SK283204B6 (sk) 2003-03-04
BG63631B1 (bg) 2002-07-31
HRP960312A2 (en) 1998-02-28
BG102188A (en) 1998-08-31
ZA966043B (en) 1997-02-03
PT839132E (pt) 2001-06-29
AU700794B2 (en) 1999-01-14
DE69611999D1 (de) 2001-04-12
CA2220455C (en) 2002-09-24
CA2220455A1 (en) 1997-02-06
PL324463A1 (en) 1998-05-25
AU6497896A (en) 1997-02-18
CZ289421B6 (cs) 2002-01-16
US6274740B1 (en) 2001-08-14
HK1018054A1 (en) 1999-12-10
NO309322B1 (no) 2001-01-15
DK0839132T3 (da) 2001-04-09
GEP20002027B (en) 2000-04-10
EP0839132A1 (en) 1998-05-06
EP0839132B1 (en) 2001-03-07
JPH11510486A (ja) 1999-09-14
KR100400805B1 (ko) 2003-12-24
SI0839132T1 (enExample) 2001-06-30
HU220343B (hu) 2001-12-28
GR3035859T3 (en) 2001-08-31
CN1190956A (zh) 1998-08-19

Similar Documents

Publication Publication Date Title
BR9609714A (pt) Processo para a produção de sal de cálcio do ácido [r-(r*,r*)] - 2 - (4-flúor-fenil) - beta, gama - di - hidróxi - 5 -(1-metil-etil) - 3 - fenil - 4 -[(fenil-amino)cabornil] - 1h - pirrol - 1 - heptanóico amorfo (2:1)
PT770615E (pt) Processo para a preparacao de di-haloazolopirimidinas
BR9400616A (pt) Processo para a preparação de 1,1,1,4,4,4-hexafluorbuteno-2
BR9608282A (pt) Processo para a produção de uma hidroxialamida
BR9608471A (pt) Processo para a preparação de um composto
BR9307861A (pt) Processo para formação de revestimento
BR9701564A (pt) Processo para a fabricação de uma biela forjada
BR9603750A (pt) Processo para designar unidade de assinante a um ponto de conexão
BR9602470A (pt) Processo em recipiente único para a preparação de 7-aril-quinona metidas 2,6-dissubstituídas
PT824517E (pt) Processo para a preparacao de cloridrato de lercanidipina
BR9307855A (pt) Processo para formação de revestimento
PT877738E (pt) Processo para a preparacao de derivados de fenil-imidazolidina
BR9610887A (pt) Processo para a preparação de um composto
BR9403906A (pt) Processo para a preparação de compostos de enxofre de trifluoretila a partir de tiolatos de 1-cloro-2,2,2-trifluoretano
BR9606199A (pt) Processo para produção de objetos
BR9610925A (pt) Processo para estabelecimento de uma união intermetálica
BR9603191A (pt) Processo para posicionamento de uma peça
BR9407024A (pt) Processo para a preparação de 4,6-diamino-5-cianopirimidinas substituídas
BR9609891A (pt) Processo para a preparação de um molho
BR9608469A (pt) Processo para a preparação de derivados do ácido carboxílico
BR9610294A (pt) Processo para a preparação de um composto
BR9603223A (pt) Processo para a preparação de aminocarboniltriazolinonas substituídas
BR9610630A (pt) Processo para a fabricação de detergentes granulares
BR9600086A (pt) Processo para a produção de hidroxialcoxibenzofenonas
AU1426197A (en) Process for the conversion of calcium sulfide

Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal
CKFC Appeal: appeal against refusal