BR9508002A - Preparado farmacêutico com uma substância ativa hidrófoba e um sistema efervecente, e processo para a produção do preparado - Google Patents
Preparado farmacêutico com uma substância ativa hidrófoba e um sistema efervecente, e processo para a produção do preparadoInfo
- Publication number
- BR9508002A BR9508002A BR9508002-3A BR9508002A BR9508002A BR 9508002 A BR9508002 A BR 9508002A BR 9508002 A BR9508002 A BR 9508002A BR 9508002 A BR9508002 A BR 9508002A
- Authority
- BR
- Brazil
- Prior art keywords
- preparation
- hydrophobic active
- pct
- active substance
- production
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Patente de Invenção:<B>"PREPARADO FARMACêUTICO COM UMA SUBSTâNCIA ATIVA HIDRóFOBA E UM SISTEMA EFERVESCENTE, E PROCESSO PARA A PRODUçãO DO PREPARADO"<D>. A presente invenção refere-se a comprimidos efervescentes farmacêuticos com pelos menos uma substância ativa hidrófoba, como por exemplo, loratadina ou Cisaprida, e um agente tensoativo, contendo vantajosamente pelo menos dois diferentes agentes tensoativos ou emulsificadores, especialmente do grupo dos ésteres de açúcar, dos polissorbatos e dos fosfolipídeos. Pelo menos um dos emulsificadores pode estar presente na mistura de modo separado do sistema efervescente e/ou granulado de substância ativa em granulado próprio. Também a substância ativa é precipitada de preferência num granulado de substância ativa próprio- talvez com a ajuda de um agente aglutinador, como por exemplo, polivinilpirrolidona- na superfície de um agente de suspensão ou agente antiaderente, como por exemplo, Aerosil^ «^ ou Avicel^ «^, podendo também conter pelo menos um dos componentes efervescentes e/ou um agente de enchimento que contém de preferência pelo menos um dos seguintes compostos: álcoois superiores, por exemplo, manitol, sorbitol ou lactose; hidrocolóides, como dextrina de malte ou dextrinas; fécula.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH01890/94A CH686865A5 (de) | 1994-06-15 | 1994-06-15 | Pharmazeutische Zubereitung mit einem hydrophoben Wirkstoff und einem Brausesystem, sowie Verfahren zur Herstellung der Zubereitung. |
| PCT/EP1995/001904 WO1995034284A1 (de) | 1994-06-15 | 1995-05-19 | Pharmazeutische zubereitung mit einem hydrophoben wirkstoff und einem brausesystem, sowie verfahren zur herstellung der zubereitung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9508002A true BR9508002A (pt) | 2000-05-30 |
Family
ID=4221002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9508002-3A BR9508002A (pt) | 1994-06-15 | 1995-05-19 | Preparado farmacêutico com uma substância ativa hidrófoba e um sistema efervecente, e processo para a produção do preparado |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US5834019A (pt) |
| EP (1) | EP0768868B1 (pt) |
| JP (1) | JPH10501535A (pt) |
| KR (1) | KR100367302B1 (pt) |
| CN (1) | CN1149071C (pt) |
| AT (1) | ATE204744T1 (pt) |
| AU (1) | AU684966B2 (pt) |
| BR (1) | BR9508002A (pt) |
| CA (1) | CA2191302C (pt) |
| CH (1) | CH686865A5 (pt) |
| CO (1) | CO4410175A1 (pt) |
| CZ (1) | CZ287807B6 (pt) |
| DE (1) | DE59509566D1 (pt) |
| ES (1) | ES2161901T3 (pt) |
| HU (1) | HU221680B1 (pt) |
| IL (1) | IL114144A (pt) |
| MX (1) | MX9606391A (pt) |
| MY (1) | MY113718A (pt) |
| NO (1) | NO314016B1 (pt) |
| NZ (1) | NZ288208A (pt) |
| PE (1) | PE42295A1 (pt) |
| PL (1) | PL180135B1 (pt) |
| SK (1) | SK281262B6 (pt) |
| TW (1) | TW457097B (pt) |
| WO (1) | WO1995034284A1 (pt) |
| ZA (1) | ZA954932B (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0803251B1 (en) * | 1996-04-23 | 2002-07-17 | Janssen Pharmaceutica N.V. | Immediate release pH-independent solid dosage form of cisapride |
| ATE220543T1 (de) * | 1996-04-23 | 2002-08-15 | Janssen Pharmaceutica Nv | Rasch-freisetzende ph-unabhängige feste dosisformen enthaltend cisaprid |
| JP2002504107A (ja) * | 1997-06-11 | 2002-02-05 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | （＋）−または（−）−シサプリドの即時放出性ｐＨ非依存的固形投薬剤形 |
| US6589555B2 (en) | 1999-12-29 | 2003-07-08 | Mahendra Pandya | Effervescent vitaceutical compositions and related methods |
| AU2002220248A1 (en) * | 2000-11-06 | 2002-05-15 | Andrx Pharmaceuticals, Inc. | Once a day antihistamine and decongestant formulation |
| EP1418945A2 (en) | 2001-03-13 | 2004-05-19 | Angiotech Pharmaceuticals, Inc. | Micellar drug delivery vehicles and uses thereof |
| US20030157170A1 (en) * | 2001-03-13 | 2003-08-21 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
| DE60220519T2 (de) * | 2001-04-20 | 2007-09-27 | The University Of British Columbia, Vancouver | Mizellares arzneistoffverabreichungssystem für hydrophobe arzneistoffe |
| EP1435910B9 (en) * | 2001-10-19 | 2010-02-03 | Isotechnika Inc. | Novel cyclosporin analog microemulsion preconcentrates |
| US8092831B2 (en) * | 2002-11-08 | 2012-01-10 | Andrx Pharmaceuticals, Llc | Antihistamine and decongestant system |
| US20050069590A1 (en) * | 2003-09-30 | 2005-03-31 | Buehler Gail K. | Stable suspensions for medicinal dosages |
| CN100381123C (zh) * | 2005-01-12 | 2008-04-16 | 南京亿华药业有限公司 | 一种氯雷他定颗粒剂及其制法 |
| CN101897732B (zh) * | 2009-05-27 | 2013-01-30 | 北京因科瑞斯医药科技有限公司 | 一种中药泡腾片剂及其制备方法 |
| CN106236713B (zh) * | 2016-08-30 | 2018-11-09 | 林州中农颖泰生物肽有限公司 | 一种七清败毒泡腾颗粒及其制备方法 |
| CN107296800A (zh) * | 2017-06-01 | 2017-10-27 | 江苏黄河药业股份有限公司 | 一种氯雷他定泡腾片及其制备方法 |
| CN112741841A (zh) * | 2019-10-29 | 2021-05-04 | 湖北真奥医药研究院有限公司 | 三维钙自乳化泡腾剂组合物及其制剂的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5356986A (en) * | 1984-12-14 | 1986-07-22 | Gergely, Gerhard | Teilchen aus euner hydrophoben oder schwerloslichen substanz und verfahren zur ihrer hydrophilisierung |
| GB8528195D0 (en) * | 1985-11-15 | 1985-12-18 | Boots Co Plc | Therapeutic compositions |
| GB9224021D0 (en) * | 1992-11-16 | 1993-01-06 | Boots Co Plc | Effervescent compositions |
| US5646131A (en) * | 1994-02-22 | 1997-07-08 | The Arab Company For Drug Industries And Medical Applicances (Acdima) | Method for solubilizing drugs using cyclodextrins and carboxylic acids |
| GB9405304D0 (en) * | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
-
1994
- 1994-06-15 CH CH01890/94A patent/CH686865A5/de not_active IP Right Cessation
-
1995
- 1995-05-19 AU AU27497/95A patent/AU684966B2/en not_active Ceased
- 1995-05-19 ES ES95922463T patent/ES2161901T3/es not_active Expired - Lifetime
- 1995-05-19 SK SK1593-96A patent/SK281262B6/sk unknown
- 1995-05-19 US US08/737,580 patent/US5834019A/en not_active Expired - Lifetime
- 1995-05-19 EP EP95922463A patent/EP0768868B1/de not_active Expired - Lifetime
- 1995-05-19 NZ NZ288208A patent/NZ288208A/en unknown
- 1995-05-19 WO PCT/EP1995/001904 patent/WO1995034284A1/de active IP Right Grant
- 1995-05-19 HU HU9603452A patent/HU221680B1/hu not_active IP Right Cessation
- 1995-05-19 CA CA2191302A patent/CA2191302C/en not_active Expired - Fee Related
- 1995-05-19 CN CNB95193578XA patent/CN1149071C/zh not_active Expired - Fee Related
- 1995-05-19 JP JP8501534A patent/JPH10501535A/ja not_active Ceased
- 1995-05-19 PL PL95317856A patent/PL180135B1/pl unknown
- 1995-05-19 KR KR1019960706945A patent/KR100367302B1/ko not_active IP Right Cessation
- 1995-05-19 DE DE59509566T patent/DE59509566D1/de not_active Expired - Lifetime
- 1995-05-19 CZ CZ19963672A patent/CZ287807B6/cs not_active IP Right Cessation
- 1995-05-19 AT AT95922463T patent/ATE204744T1/de active
- 1995-05-19 MX MX9606391A patent/MX9606391A/es not_active IP Right Cessation
- 1995-05-19 BR BR9508002-3A patent/BR9508002A/pt active Search and Examination
- 1995-06-14 IL IL11414495A patent/IL114144A/xx not_active IP Right Cessation
- 1995-06-14 ZA ZA954932A patent/ZA954932B/xx unknown
- 1995-06-14 CO CO95026284A patent/CO4410175A1/es unknown
- 1995-06-14 PE PE1995271312A patent/PE42295A1/es not_active Application Discontinuation
- 1995-06-15 MY MYPI95001623A patent/MY113718A/en unknown
- 1995-06-15 TW TW084106115A patent/TW457097B/zh not_active IP Right Cessation
-
1996
- 1996-12-09 NO NO19965244A patent/NO314016B1/no unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB36 | Technical and formal requirements: requirement - article 36 of industrial property law | ||
| HJEG | Technical examination (opinion): technical examination (opinion) related to article 229 of industrial property law | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B11D | Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time |