ES2161901T3 - Preparacion farmaceutica con una sustancia activa hidrofoba y un sistema efervescente, asi como procedimiento para la fabricacion de la preparacion. - Google Patents

Preparacion farmaceutica con una sustancia activa hidrofoba y un sistema efervescente, asi como procedimiento para la fabricacion de la preparacion.

Info

Publication number
ES2161901T3
ES2161901T3 ES95922463T ES95922463T ES2161901T3 ES 2161901 T3 ES2161901 T3 ES 2161901T3 ES 95922463 T ES95922463 T ES 95922463T ES 95922463 T ES95922463 T ES 95922463T ES 2161901 T3 ES2161901 T3 ES 2161901T3
Authority
ES
Spain
Prior art keywords
preparation
pct
substance
hydrophobe
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95922463T
Other languages
English (en)
Inventor
Gerhard Gergely
Irmgard Gergely
Thomas Gergely
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2161901T3 publication Critical patent/ES2161901T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

TABLETAS FARMACEUTICAS EFERVESCENTES CON AL MENOS UN PRINCIPIO ACTIVO HIDROFOBICO, COMO P. E. LORATADINA O CISAPRIDA Y UN TENSIOACTIVO, CONTIENEN VNTAJOSAMENTE AL MENOS DOS TENSIOACTIVOS O EMULSIONANTES DIFERENTES, EN PARTICULAR DEL GRUPO DE LOS ESTERES DEL AZUCAR, POLISORBATOS Y FOSFOLIPIDOS. AL MENOS UNO DE LOS EMULSIONANTES PUEDE ESTAR PRESENTE EN LA MEZCLA DE FORMA GRANULADA SEPARADO DEL SISTEMA EFERVESCENTE Y/O GRANULADO DEL PRINCIPIO ACTIVO. PREFERIBLEMENTE TAMBIEN EL PRINCIPIO ACTIVO ESTA PRECIPITADO EN FORMA DE GRANULOS - POR EJEMPLO CON LA AYUDA DE UN LIGANTE, TAL QUE LA POLIVINIL-PIRROLIDONA - EN LA SUPERFICIE DE UNA SUSTANCIA EN SUSPENSION O DE UNA SUSTANCIA ANTIADHESIVA, COMO P. E. AEROSIL{SUP,R} O AVICEL{SUP,R}, Y PUEDE CONTENER ADEMAS AL MENOS UNO DE LOS COMPONENTES EFERVESCENTES Y/O UNA SUSTANCIA DE RELLENO, QUE ES PREFERIBLEMENTE AL MENOS UNO DE LOS SIGUIENTES COMPUESTOS: ALCOHOLES GRANDES, P. E. MANITOL, SORBITOL O LACTOSA; HIDROCOLOIDES TALES COMO MALTODEXTRINA O DEXTRINA;ALMIDON.
ES95922463T 1994-06-15 1995-05-19 Preparacion farmaceutica con una sustancia activa hidrofoba y un sistema efervescente, asi como procedimiento para la fabricacion de la preparacion. Expired - Lifetime ES2161901T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH01890/94A CH686865A5 (de) 1994-06-15 1994-06-15 Pharmazeutische Zubereitung mit einem hydrophoben Wirkstoff und einem Brausesystem, sowie Verfahren zur Herstellung der Zubereitung.

Publications (1)

Publication Number Publication Date
ES2161901T3 true ES2161901T3 (es) 2001-12-16

Family

ID=4221002

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95922463T Expired - Lifetime ES2161901T3 (es) 1994-06-15 1995-05-19 Preparacion farmaceutica con una sustancia activa hidrofoba y un sistema efervescente, asi como procedimiento para la fabricacion de la preparacion.

Country Status (26)

Country Link
US (1) US5834019A (es)
EP (1) EP0768868B1 (es)
JP (1) JPH10501535A (es)
KR (1) KR100367302B1 (es)
CN (1) CN1149071C (es)
AT (1) ATE204744T1 (es)
AU (1) AU684966B2 (es)
BR (1) BR9508002A (es)
CA (1) CA2191302C (es)
CH (1) CH686865A5 (es)
CO (1) CO4410175A1 (es)
CZ (1) CZ287807B6 (es)
DE (1) DE59509566D1 (es)
ES (1) ES2161901T3 (es)
HU (1) HU221680B1 (es)
IL (1) IL114144A (es)
MX (1) MX9606391A (es)
MY (1) MY113718A (es)
NO (1) NO314016B1 (es)
NZ (1) NZ288208A (es)
PE (1) PE42295A1 (es)
PL (1) PL180135B1 (es)
SK (1) SK281262B6 (es)
TW (1) TW457097B (es)
WO (1) WO1995034284A1 (es)
ZA (1) ZA954932B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69713948D1 (de) * 1996-04-23 2002-08-22 Janssen Pharmaceutica Nv Rasch-freisetzende pH-unabhängige feste Dosisformen enthaltend Cisaprid
EP0803251B1 (en) * 1996-04-23 2002-07-17 Janssen Pharmaceutica N.V. Immediate release pH-independent solid dosage form of cisapride
WO1998056364A1 (en) * 1997-06-11 1998-12-17 Janssen Pharmaceutica N.V. IMMEDIATE RELEASE pH-INDEPENDENT SOLID DOSAGE FORM OF (+)- OR (-)-CISAPRIDE
US6589555B2 (en) 1999-12-29 2003-07-08 Mahendra Pandya Effervescent vitaceutical compositions and related methods
AU2002220248A1 (en) * 2000-11-06 2002-05-15 Andrx Pharmaceuticals, Inc. Once a day antihistamine and decongestant formulation
US20030157170A1 (en) * 2001-03-13 2003-08-21 Richard Liggins Micellar drug delivery vehicles and precursors thereto and uses thereof
CA2440935A1 (en) * 2001-03-13 2002-09-19 Richard Liggins Micellar drug delivery vehicles and precursors thereto and uses thereof
DK1392254T3 (da) * 2001-04-20 2007-07-02 Univ British Columbia Micelle-lægemiddelindgivelsessystem for hydrofobe lægemidler
DK1435910T3 (da) * 2001-10-19 2009-11-09 Isotechnika Inc Nye cyclosporinanaloge mikroemulsionsprækoncentrater
US8092831B2 (en) * 2002-11-08 2012-01-10 Andrx Pharmaceuticals, Llc Antihistamine and decongestant system
US20050069590A1 (en) * 2003-09-30 2005-03-31 Buehler Gail K. Stable suspensions for medicinal dosages
CN100381123C (zh) * 2005-01-12 2008-04-16 南京亿华药业有限公司 一种氯雷他定颗粒剂及其制法
CN101897732B (zh) * 2009-05-27 2013-01-30 北京因科瑞斯医药科技有限公司 一种中药泡腾片剂及其制备方法
CN106236713B (zh) * 2016-08-30 2018-11-09 林州中农颖泰生物肽有限公司 一种七清败毒泡腾颗粒及其制备方法
CN107296800A (zh) * 2017-06-01 2017-10-27 江苏黄河药业股份有限公司 一种氯雷他定泡腾片及其制备方法
CN112741841A (zh) * 2019-10-29 2021-05-04 湖北真奥医药研究院有限公司 三维钙自乳化泡腾剂组合物及其制剂的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3584522D1 (de) * 1984-12-14 1991-11-28 Gergely Gerhard Teilchen aus einer hydrophoben oder schwerloeslichen substanz und verfahren zu ihrer hydrophilisierung.
GB8528195D0 (en) * 1985-11-15 1985-12-18 Boots Co Plc Therapeutic compositions
GB9224021D0 (en) * 1992-11-16 1993-01-06 Boots Co Plc Effervescent compositions
US5646131A (en) * 1994-02-22 1997-07-08 The Arab Company For Drug Industries And Medical Applicances (Acdima) Method for solubilizing drugs using cyclodextrins and carboxylic acids
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs

Also Published As

Publication number Publication date
US5834019A (en) 1998-11-10
CH686865A5 (de) 1996-07-31
AU684966B2 (en) 1998-01-08
TW457097B (en) 2001-10-01
WO1995034284A1 (de) 1995-12-21
PL180135B1 (pl) 2000-12-29
CZ367296A3 (en) 1997-04-16
CN1149071C (zh) 2004-05-12
ATE204744T1 (de) 2001-09-15
IL114144A (en) 1999-07-14
CN1151693A (zh) 1997-06-11
CA2191302A1 (en) 1995-12-21
KR970703131A (ko) 1997-07-03
CZ287807B6 (en) 2001-02-14
BR9508002A (pt) 2000-05-30
HU221680B1 (hu) 2002-12-28
PE42295A1 (es) 1995-12-28
SK159396A3 (en) 1997-08-06
NO965244D0 (no) 1996-12-09
JPH10501535A (ja) 1998-02-10
EP0768868B1 (de) 2001-08-29
ZA954932B (en) 1996-02-07
AU2749795A (en) 1996-01-05
CA2191302C (en) 2010-08-10
MX9606391A (es) 1997-07-31
SK281262B6 (sk) 2001-01-18
KR100367302B1 (ko) 2003-04-16
NZ288208A (en) 1998-08-26
DE59509566D1 (de) 2001-10-04
NO314016B1 (no) 2003-01-20
HUT75674A (en) 1997-05-28
HU9603452D0 (en) 1997-02-28
IL114144A0 (en) 1995-10-31
NO965244L (no) 1997-02-13
EP0768868A1 (de) 1997-04-23
CO4410175A1 (es) 1997-01-09
PL317856A1 (en) 1997-04-28
MY113718A (en) 2002-05-31

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