BR112022019754A2 - Ensaios para detecção de sars-cov-2 - Google Patents
Ensaios para detecção de sars-cov-2Info
- Publication number
- BR112022019754A2 BR112022019754A2 BR112022019754A BR112022019754A BR112022019754A2 BR 112022019754 A2 BR112022019754 A2 BR 112022019754A2 BR 112022019754 A BR112022019754 A BR 112022019754A BR 112022019754 A BR112022019754 A BR 112022019754A BR 112022019754 A2 BR112022019754 A2 BR 112022019754A2
- Authority
- BR
- Brazil
- Prior art keywords
- cov
- sars
- detection tests
- detection
- assays
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/10—Detection mode being characterised by the assay principle
- C12Q2565/101—Interaction between at least two labels
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Radar Systems Or Details Thereof (AREA)
Abstract
ENSAIOS PARA DETECÇÃO DE SARS-COV-2. A presente invenção é direcionada a métodos para avaliar a presença de SARS-CoV-2 em uma amostra, incluindo uma amostra clínica, e a oligonucleotídeos, reagentes e kits úteis em tais ensaios. Em particular, a presente invenção é direcionada a tais ensaios que são rápidos, precisos e específicos para a detecção de SARS-CoV-2 usando oligonucleotídeos marcados hibridizando com o gene ORF1ab e/ou S.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT102020000006754A IT202000006754A1 (it) | 2020-03-31 | 2020-03-31 | Saggi per la rivelazione di SARS-CoV-2 |
PCT/EP2021/058426 WO2021198326A1 (en) | 2020-03-31 | 2021-03-31 | Assays for the detection of sars-cov-2 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022019754A2 true BR112022019754A2 (pt) | 2022-12-13 |
Family
ID=70978427
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022019754A BR112022019754A2 (pt) | 2020-03-31 | 2021-03-31 | Ensaios para detecção de sars-cov-2 |
Country Status (9)
Country | Link |
---|---|
US (1) | US10815539B1 (pt) |
EP (1) | EP4127248A1 (pt) |
AU (1) | AU2021245344A1 (pt) |
BR (1) | BR112022019754A2 (pt) |
CA (1) | CA3174243A1 (pt) |
IL (1) | IL296944A (pt) |
IT (1) | IT202000006754A1 (pt) |
TW (1) | TW202140799A (pt) |
WO (1) | WO2021198326A1 (pt) |
Families Citing this family (35)
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US20210040571A1 (en) * | 2018-07-25 | 2021-02-11 | Sense Biodetection Limited | Nucleic acid detection method |
CN111778264B (zh) * | 2020-07-14 | 2021-06-29 | 广州佰芮慷生物科技有限公司 | 基于新型腺病毒载体Sad23L和/或Ad49L的新型冠状病毒肺炎疫苗 |
US11494571B2 (en) | 2020-07-22 | 2022-11-08 | Donald Channing Cooper | Computer vision method for improved automated image capture and analysis of rapid diagnostic test devices |
CN114067907B (zh) * | 2020-07-31 | 2022-07-08 | 普瑞基准生物医药(苏州)有限公司 | 一种准确鉴定rna病毒基因组变异的方法 |
CN112063764A (zh) * | 2020-10-28 | 2020-12-11 | 江苏科德生物医药科技有限公司 | 一种用于新型冠状病毒核酸检测的多重实时荧光rt-pcr引物探针组合物及试剂盒 |
CN112266980A (zh) * | 2020-11-03 | 2021-01-26 | 郑州大学 | 一种新型冠状病毒2019-nCoV实时荧光PCR检测引物和探针、试剂盒和方法 |
TW202237626A (zh) * | 2020-11-12 | 2022-10-01 | 美商帝斯肯醫療公司 | Sars-cov-2免疫顯性肽構築體及其用途 |
WO2022108460A2 (en) * | 2020-11-19 | 2022-05-27 | University Of The Philippines Manila | Peptide-based antigenic constructs recognized by immunoglobulins that bind to protein epitopes of severe acute respiratory syndrome coronavirus 2 (sars-cov-2) |
US20220162600A1 (en) * | 2020-11-23 | 2022-05-26 | Zunyi Yang | Compositions for the Multiplexed Detection of Viruses |
CN112391496A (zh) * | 2020-11-27 | 2021-02-23 | 魏尔啸实验室科技(杭州)有限公司 | 一种新型冠状病毒联合呼吸道病毒检测引物与探针组合、检测试剂盒及应用 |
CN113151582B (zh) * | 2020-12-12 | 2022-01-07 | 杭州迪安医学检验中心有限公司 | 一种检测新型冠状病毒(SARS-CoV-2)的引物探针和试剂盒 |
CN112662810A (zh) * | 2020-12-18 | 2021-04-16 | 郑州安图生物工程股份有限公司 | 检测新型冠状病毒2019-nCoV的引物探针组合 |
CN112831600A (zh) * | 2020-12-25 | 2021-05-25 | 连云港市妇幼保健院(连云港市第三人民医院) | 一种检测SARS-CoV-2病毒的引物探针组合及其应用 |
CN112662811A (zh) * | 2020-12-25 | 2021-04-16 | 北京美康基因科学股份有限公司 | 一种新型冠状病毒4基因区段多重核酸检测试剂盒及其应用 |
WO2022171584A1 (en) | 2021-02-10 | 2022-08-18 | Procomcure Biotech Gmbh | Assays for the detection of sars-cov-2 mutants |
EP4043588A1 (en) | 2021-02-10 | 2022-08-17 | Procomcure Biotech GmbH | Assays for the detection of sars-cov-2 mutants |
GB202102310D0 (en) * | 2021-02-18 | 2021-04-07 | Primer Design Ltd | Composition and method |
CA3213108A1 (en) * | 2021-03-09 | 2022-09-15 | Robert E. Blomquist | Extraction-free pathogen testing methods |
CN113150133B (zh) * | 2021-03-15 | 2022-10-11 | 安源医药科技(上海)有限公司 | 针对SARS-CoV-2的单克隆抗体或其抗原结合片段 |
CN113025752B (zh) * | 2021-03-24 | 2023-07-21 | 广州金域医学检验中心有限公司 | 用于2019-nCoV和SARS病毒PCR检测的内参基因、试剂盒及检测方法 |
WO2022201104A1 (en) * | 2021-03-26 | 2022-09-29 | The Royal Institution For The Advancement Of Learning/Mcgill University | Compositions, methods and kits comprising polyinosinic acid (poly(i)) for polymerase chain reaction (pcr) |
WO2022221605A2 (en) * | 2021-04-14 | 2022-10-20 | The Board Of Regents Of The University Of Texas System | Detection of sars-cov-2 variant |
CN113293230A (zh) * | 2021-04-27 | 2021-08-24 | 军事科学院军事医学研究院军事兽医研究所 | 新型冠状病毒covid-19荧光定量pcr检测引物和探针、试剂盒及检测方法 |
CN113073150B (zh) * | 2021-04-28 | 2023-01-10 | 领航医学科技(深圳)有限公司 | 一种用于新型冠状病毒及其变异株的数字pcr检测试剂盒 |
CN113186346A (zh) * | 2021-05-08 | 2021-07-30 | 北京华诺奥美医学检验实验室有限公司 | 一种新型冠状病毒核酸pcr-胶体金免疫层析法检测试剂盒 |
WO2022240381A1 (en) * | 2021-05-14 | 2022-11-17 | Turkiye Saglik Enstituleri Baskanligi | A method and kit for quantitative detection of sars-cov-2 by real-time pcr |
CN113151608B (zh) * | 2021-05-26 | 2021-11-05 | 华中农业大学 | 检测具有感染性SARS-CoV-2的PCR靶序列、引物和探针及应用 |
CN113308574B (zh) * | 2021-06-01 | 2022-03-15 | 上海伯杰医疗科技股份有限公司 | 一种用于新型冠状病毒突变株检测的引物探针组合、试剂盒及分型检测方法 |
WO2023015259A2 (en) * | 2021-08-05 | 2023-02-09 | Mammoth Biosciences, Inc. | Methods and compositions for improved snp discrimination |
GB202113085D0 (en) * | 2021-09-14 | 2021-10-27 | Primer Design Ltd | Composition and method |
WO2023057799A1 (en) * | 2021-10-08 | 2023-04-13 | National Cheng Kung University | Methods and kits for detecting severe acute respiratory syndrome coronavirus 2 |
CN113881812B (zh) * | 2021-12-03 | 2022-02-15 | 深圳联合医学科技有限公司 | 检测SARS-CoV-2突变株的组合物、试剂盒、方法及其用途 |
WO2023119307A1 (en) * | 2021-12-23 | 2023-06-29 | Krishnamurthy Girish | Primer and probes for detection of omicron variant of sars-cov-2, methods and uses thereof |
EP4253560A1 (en) | 2022-03-31 | 2023-10-04 | Consejo Superior de Investigaciones Cientificas | Enhanced detection of single-stranded nucleic acids using fokl-assisted digestion |
CN114875178B (zh) * | 2022-05-11 | 2024-04-12 | 山东大学 | 一种基于杂交链式反应的SARS-CoV-2检测体系及检测方法 |
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CN111394511B (zh) * | 2020-03-09 | 2021-01-12 | 深圳市梓健生物科技有限公司 | 2019新型冠状病毒的检测引物组、探针组及检测试剂盒 |
-
2020
- 2020-03-31 IT IT102020000006754A patent/IT202000006754A1/it unknown
- 2020-04-01 US US16/837,364 patent/US10815539B1/en active Active
-
2021
- 2021-03-31 WO PCT/EP2021/058426 patent/WO2021198326A1/en unknown
- 2021-03-31 BR BR112022019754A patent/BR112022019754A2/pt unknown
- 2021-03-31 CA CA3174243A patent/CA3174243A1/en active Pending
- 2021-03-31 TW TW110111852A patent/TW202140799A/zh unknown
- 2021-03-31 EP EP21715617.3A patent/EP4127248A1/en active Pending
- 2021-03-31 AU AU2021245344A patent/AU2021245344A1/en active Pending
-
2022
- 2022-09-29 IL IL296944A patent/IL296944A/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2021245344A1 (en) | 2022-12-01 |
EP4127248A1 (en) | 2023-02-08 |
IT202000006754A1 (it) | 2021-10-01 |
TW202140799A (zh) | 2021-11-01 |
US10815539B1 (en) | 2020-10-27 |
WO2021198326A1 (en) | 2021-10-07 |
CA3174243A1 (en) | 2021-10-07 |
IL296944A (en) | 2022-12-01 |
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