AR055437A1 - Deteccion de metilacion genetica - Google Patents

Deteccion de metilacion genetica

Info

Publication number
AR055437A1
AR055437A1 ARP060104052A ARP060104052A AR055437A1 AR 055437 A1 AR055437 A1 AR 055437A1 AR P060104052 A ARP060104052 A AR P060104052A AR P060104052 A ARP060104052 A AR P060104052A AR 055437 A1 AR055437 A1 AR 055437A1
Authority
AR
Argentina
Prior art keywords
methodation
genetic
detection
methylation status
diagnosing
Prior art date
Application number
ARP060104052A
Other languages
English (en)
Original Assignee
Veridex Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Veridex Llc filed Critical Veridex Llc
Publication of AR055437A1 publication Critical patent/AR055437A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Abstract

Se describen métodos, kits y composiciones para detectar el estado de metilacion de diversos genes utiles en diversas aplicaciones de diagnostico que involucran trastornos proliferativos sospechados tales como cáncer de prostata. Reivindicacion 1: Un método para diagnosticar la presencia o predecir el curso de un trastorno proliferativo que comprende determinar el estado de metilacion de un Marcador en una muestra biologica con el uso e un reactivo seleccionado del grupo formado por: SEC: ID N° 1-35 y 44-53.
ARP060104052A 2005-09-15 2006-09-15 Deteccion de metilacion genetica AR055437A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71779005P 2005-09-15 2005-09-15

Publications (1)

Publication Number Publication Date
AR055437A1 true AR055437A1 (es) 2007-08-22

Family

ID=37682657

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060104052A AR055437A1 (es) 2005-09-15 2006-09-15 Deteccion de metilacion genetica

Country Status (12)

Country Link
US (1) US20070059753A1 (es)
EP (1) EP1764419B1 (es)
JP (1) JP2007075114A (es)
CN (1) CN1966724A (es)
AR (1) AR055437A1 (es)
AT (1) ATE555214T1 (es)
AU (1) AU2006213972A1 (es)
BR (1) BRPI0604761A (es)
CA (1) CA2561991A1 (es)
DK (1) DK1764419T3 (es)
ES (1) ES2386729T3 (es)
IL (1) IL178118A0 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP312998A0 (en) * 1998-04-23 1998-05-14 Commonwealth Scientific And Industrial Research Organisation Diagnostic assay
WO2007081791A2 (en) * 2006-01-04 2007-07-19 The Johns Hopkins University Compare-ms:method rapid, sensitive and accurate detection of dna methylation
TWI335354B (en) * 2006-09-27 2011-01-01 Univ Hong Kong Chinese Methods for the detection of the degree of the methylation of a target dna and kits
NZ596545A (en) * 2007-09-17 2013-05-31 Glaxosmithkline Biolog Sa Improved detection of mage-a expression
EP2245192A4 (en) * 2008-01-22 2011-04-13 Veridex Llc DETECTION OF HYPERMETHYLATION OF GSTP1 IN PROSTATE CANCER
JP2011530287A (ja) * 2008-08-05 2011-12-22 ベリデックス・エルエルシー 前立腺癌メチル化分析
CA2826696C (en) 2011-02-02 2019-12-03 Exact Sciences Corporation Digital sequence analysis of dna methylation
GB201322034D0 (en) 2013-12-12 2014-01-29 Almac Diagnostics Ltd Prostate cancer classification
EP3140421B8 (en) 2014-05-09 2020-05-06 Eurofins LifeCodexx GmbH Detection of dna that originates from a specific cell-type and related methods
EP2942400A1 (en) 2014-05-09 2015-11-11 Lifecodexx AG Multiplex detection of DNA that originates from a specific cell-type
HUE050491T2 (hu) 2015-11-10 2020-12-28 Eurofins Lifecodexx Gmbh Magzati kromoszomális aneuploidiák kimutatása olyan DNS régiókat alkalmazva, amelyek különbözõképpen vannak metilezve a magzat és a terhes nõstény között
CN113215260A (zh) * 2021-06-18 2021-08-06 杭州昱鼎生物科技有限公司 一种gstp1，apc和rassf1在制备前列腺癌标志物中的应用及其试剂盒

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5536648A (en) * 1988-12-09 1996-07-16 Amrad Corporation Limited Amplified DNA assay using a double stranded DNA binding protein
GB9609441D0 (en) 1996-05-04 1996-07-10 Zeneca Ltd Process
US6017704A (en) * 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
AUPP312998A0 (en) * 1998-04-23 1998-05-14 Commonwealth Scientific And Industrial Research Organisation Diagnostic assay
GB9812768D0 (en) 1998-06-13 1998-08-12 Zeneca Ltd Methods
US6686155B2 (en) * 2001-06-14 2004-02-03 Response Genetics, Inc. Method of determining a chemotherapeutic regimen based on glutathione-S-transferase pi expression
JP4381142B2 (ja) * 2001-11-16 2009-12-09 ザ ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン 前立腺癌の検出法
US20040146868A1 (en) * 2003-01-24 2004-07-29 Epigenomics Ag Methods and nucleic acids for the analysis of CpG dinucleotide methylation status associated with the development of peripheral zone prostate cancer
AU2003900368A0 (en) * 2003-01-24 2003-02-13 Human Genetic Signatures Pty Ltd Assay for nucleic acid molecules
WO2004087957A2 (en) 2003-04-03 2004-10-14 Oncomethylome Sciences S.A. Hypermethylated genes and cervical cancer
ATE494390T1 (de) * 2003-06-23 2011-01-15 Epigenomics Ag Verfahren und nukleinsäuren zur analyse von störungen der proliferation von kolonzellen
EP1649050A2 (en) 2003-06-24 2006-04-26 Epigenomics AG Improved heavymethyl assay for the methylation analysis of the gstpi gene
EP1692264A2 (en) * 2003-10-28 2006-08-23 The Johns Hopkins University Quantitative multiplex methylation-specific pcr

Also Published As

Publication number Publication date
CA2561991A1 (en) 2007-03-15
ES2386729T3 (es) 2012-08-28
EP1764419A2 (en) 2007-03-21
AU2006213972A1 (en) 2007-03-29
US20070059753A1 (en) 2007-03-15
EP1764419B1 (en) 2012-04-25
IL178118A0 (en) 2006-12-31
ATE555214T1 (de) 2012-05-15
JP2007075114A (ja) 2007-03-29
DK1764419T3 (da) 2012-08-06
BRPI0604761A (pt) 2007-08-28
EP1764419A3 (en) 2007-06-13
CN1966724A (zh) 2007-05-23

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