ATE476498T1 - Neuer mit sars verbunden coronavirus stamm und seine verwendungen - Google Patents

Neuer mit sars verbunden coronavirus stamm und seine verwendungen

Info

Publication number
ATE476498T1
ATE476498T1 AT04805625T AT04805625T ATE476498T1 AT E476498 T1 ATE476498 T1 AT E476498T1 AT 04805625 T AT04805625 T AT 04805625T AT 04805625 T AT04805625 T AT 04805625T AT E476498 T1 ATE476498 T1 AT E476498T1
Authority
AT
Austria
Prior art keywords
fragments
isolated
positions
sars
genome
Prior art date
Application number
AT04805625T
Other languages
English (en)
Inventor
Der Werf Sylvie Van
Nicolas Escriou
Bernadette Crescenzo-Chaigne
Jean-Claude Manuguerra
Frederik Kunst
Benoit Callendret
Jean-Michel Betton
Valerie Lorin
Sylvie Gerbaud
Ana Maria Burguiere
Saliha Azebi
Pierre Charneau
Frederic Tangy
Chantal Combredet
Jean-Francois Delagneau
Monique Martin
Original Assignee
Pasteur Institut
Centre Nat Rech Scient
Univ Paris Vii
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0314152A external-priority patent/FR2862981B1/fr
Priority claimed from FR0314151A external-priority patent/FR2862974B1/fr
Application filed by Pasteur Institut, Centre Nat Rech Scient, Univ Paris Vii filed Critical Pasteur Institut
Application granted granted Critical
Publication of ATE476498T1 publication Critical patent/ATE476498T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/165—Coronaviridae, e.g. avian infectious bronchitis virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
AT04805625T 2003-12-02 2004-12-02 Neuer mit sars verbunden coronavirus stamm und seine verwendungen ATE476498T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0314152A FR2862981B1 (fr) 2003-12-02 2003-12-02 Nouvelle souche de coronavirus associe au sras et ses applications
FR0314151A FR2862974B1 (fr) 2003-12-02 2003-12-02 Utilisation des proteines et des peptides codes par le genome d'une nouvelle souche de coronavirus associe au sras
PCT/FR2004/003106 WO2005056584A2 (fr) 2003-12-02 2004-12-02 Nouvelle souche de coronavirus associe au sras et ses applications.

Publications (1)

Publication Number Publication Date
ATE476498T1 true ATE476498T1 (de) 2010-08-15

Family

ID=34680402

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04805625T ATE476498T1 (de) 2003-12-02 2004-12-02 Neuer mit sars verbunden coronavirus stamm und seine verwendungen

Country Status (9)

Country Link
US (4) US20070275002A1 (de)
EP (4) EP2275534A1 (de)
JP (3) JP5090741B2 (de)
AT (1) ATE476498T1 (de)
CA (2) CA2549188A1 (de)
DE (1) DE602004028506D1 (de)
ES (1) ES2396127T3 (de)
PL (1) PL1697507T3 (de)
WO (2) WO2005056781A1 (de)

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DE602006015180D1 (de) * 2006-07-25 2010-08-12 Pasteur Institut Rekombinanter Mycobakteriumstamm, der ein FAP Protein aus Mycobakterium unter der Kontrolle eines Promotors, der unter hypoxischen Konditionen aktiv ist, exprimiert, und dessen Verwendung zur Tumortherapie
EP1939214B1 (de) 2006-12-22 2013-07-10 Institut Pasteur Zellen und Methoden zur Generierung von Nichtsegmentierter Negativ-Strang-RNA-Viren
GB0711858D0 (en) * 2007-06-19 2007-07-25 Glaxosmithkline Biolog Sa Vaccine
GB0822001D0 (en) * 2008-12-02 2009-01-07 Glaxosmithkline Biolog Sa Vaccine
WO2012142213A2 (en) 2011-04-15 2012-10-18 The Johns Hopkins University Safe sequencing system
CN109457030B (zh) 2012-10-29 2022-02-18 约翰·霍普金斯大学 卵巢和子宫内膜癌的帕帕尼科拉乌测试
GB201318804D0 (en) * 2013-10-24 2013-12-11 Adaptimmune Ltd Vectors for transgene expression
EP3183351A2 (de) 2014-07-18 2017-06-28 Celltheon Corporation Methoden und zusammensetzungen zur expression von polypeptiden in einer zelle
US10072309B1 (en) * 2015-05-08 2018-09-11 Dougbeh-Chris Nyan Methods for real-time multiplex isothermal detection and identification of bacterial, viral, and protozoan nucleic acids
WO2017027653A1 (en) 2015-08-11 2017-02-16 The Johns Hopkins University Assaying ovarian cyst fluid
BR112020002555A2 (pt) 2017-08-07 2020-08-11 The Johns Hopkins University métodos e materiais para avaliar e tratar câncer
WO2021160346A1 (en) * 2020-02-13 2021-08-19 Institut Pasteur Nucleic acid vaccine against the sars-cov-2 coronavirus
WO2021163456A1 (en) * 2020-02-14 2021-08-19 Epivax, Inc. T cell epitopes and related compositions useful in the prevention, diagnosis, and treatment of covid-19
GB2594683A (en) * 2020-02-17 2021-11-10 Vaxbio Ltd Vaccine
CN111334608B (zh) * 2020-02-19 2022-04-12 北京亿森宝生物科技有限公司 用于检测新型冠状病毒2019-nCoV的双重荧光冻干微芯片、试剂盒及方法
CN113186226B (zh) * 2020-02-25 2022-08-05 广州复能基因有限公司 Rna病毒核酸检测参照标准品及其用途
WO2021188906A1 (en) * 2020-03-19 2021-09-23 Nature's Toolbox, Inc. Novel mrna-based covid-19 multi-valent vaccine and methods of scaled production of the same
WO2021188966A1 (en) * 2020-03-19 2021-09-23 Massachusetts Institute Of Technology Sars-cov-2 spike protein binding peptides
US20230149534A1 (en) * 2020-03-20 2023-05-18 BioVaxys Inc. Haptenized coronavirus spike proteins
WO2021189032A1 (en) * 2020-03-20 2021-09-23 Yu Ruey J Coronavirus: early detection and treatment
WO2021188837A1 (en) * 2020-03-20 2021-09-23 The Johns Hopkins University Prophylaxis and treatment of pathogenic coronavirus infections
US20230122364A1 (en) * 2020-03-27 2023-04-20 Vanderbilt University HUMAN MONOCLONAL ANTIBODIES TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-CoV-2)
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US20210311054A1 (en) 2020-04-01 2021-10-07 Institut Pasteur Severe acute respiratory syndrome (sars) - associated coronavirus diagnostics
US11815513B2 (en) 2020-04-01 2023-11-14 Institut Pasteur Severe acute respiratory syndrome (SARS)-associated coronavirus diagnostics
US10948490B1 (en) * 2020-04-01 2021-03-16 Institut Pasteur Severe acute respiratory syndrome (SARS)—associated coronavirus diagnostics
WO2021205083A2 (fr) 2020-04-11 2021-10-14 Finindsutria Srl Composition pour la prévention ou le traitement du covid-19
WO2021213924A1 (en) 2020-04-22 2021-10-28 BioNTech SE Coronavirus vaccine
WO2021220137A2 (en) * 2020-04-27 2021-11-04 Sapir Pharmaceuticals Inc. Pannexin-1 inhibitors for the treatment of sars-cov-2 infected covid-19 patients with or without an associated acute respiratory syndrome
WO2021236869A2 (en) * 2020-05-20 2021-11-25 The Johns Hopkins University Virus detection methods
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CN111830120B (zh) * 2020-06-10 2023-06-09 北京东西分析仪器有限公司 应用质谱系统鉴定新冠病毒的试剂盒及其使用方法
US20230242625A1 (en) * 2020-06-12 2023-08-03 The Penn State Research Foundation Pandemic-preparedness cocktail to fight coronavirus outbreaks
WO2022150740A1 (en) * 2021-01-11 2022-07-14 Board Of Regents, The University Of Texas System Cross-reactive antibodies recognizing the coronavirus spike s2 domain
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Also Published As

Publication number Publication date
DE602004028506D1 (de) 2010-09-16
ES2396127T3 (es) 2013-02-19
WO2005056584A3 (fr) 2005-08-25
JP2007536907A (ja) 2007-12-20
JP2007512826A (ja) 2007-05-24
EP1697507B1 (de) 2012-09-19
US20110065089A1 (en) 2011-03-17
US20120082693A1 (en) 2012-04-05
EP1694829A2 (de) 2006-08-30
EP2275534A1 (de) 2011-01-19
EP1694829B1 (de) 2010-08-04
EP2361974A1 (de) 2011-08-31
US20070128224A1 (en) 2007-06-07
CA2549188A1 (fr) 2005-06-23
EP1697507A1 (de) 2006-09-06
WO2005056781A1 (fr) 2005-06-23
PL1697507T3 (pl) 2013-03-29
US8343718B2 (en) 2013-01-01
US20070275002A1 (en) 2007-11-29
JP5090741B2 (ja) 2012-12-05
JP5054384B2 (ja) 2012-10-24
JP2012165750A (ja) 2012-09-06
WO2005056584A2 (fr) 2005-06-23
US7736850B2 (en) 2010-06-15
CA2549594A1 (fr) 2005-06-23

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