BR112021005580A2 - usos de éster etílico de ácido eicosapentaenoico (e-epa) para reduzir o risco de eventos cardiovasculares em um indivíduo - Google Patents

usos de éster etílico de ácido eicosapentaenoico (e-epa) para reduzir o risco de eventos cardiovasculares em um indivíduo Download PDF

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Publication number
BR112021005580A2
BR112021005580A2 BR112021005580-0A BR112021005580A BR112021005580A2 BR 112021005580 A2 BR112021005580 A2 BR 112021005580A2 BR 112021005580 A BR112021005580 A BR 112021005580A BR 112021005580 A2 BR112021005580 A2 BR 112021005580A2
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BR
Brazil
Prior art keywords
subject
fact
cardiovascular
epa
risk
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BR112021005580-0A
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English (en)
Portuguese (pt)
Inventor
Paresh Soni
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Amarin Pharmaceuticals Ireland Limited
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=69884391&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112021005580(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amarin Pharmaceuticals Ireland Limited filed Critical Amarin Pharmaceuticals Ireland Limited
Publication of BR112021005580A2 publication Critical patent/BR112021005580A2/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR112021005580-0A 2018-09-24 2019-04-22 usos de éster etílico de ácido eicosapentaenoico (e-epa) para reduzir o risco de eventos cardiovasculares em um indivíduo BR112021005580A2 (pt)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201862735680P 2018-09-24 2018-09-24
US201862735670P 2018-09-24 2018-09-24
US62/735,670 2018-09-24
US62/735,680 2018-09-24
US201862758387P 2018-11-09 2018-11-09
US62/758,387 2018-11-09
US201962813888P 2019-03-05 2019-03-05
US62/813,888 2019-03-05
US201962818514P 2019-03-14 2019-03-14
US62/818.514 2019-03-14
PCT/US2019/028553 WO2020068163A1 (en) 2018-09-24 2019-04-22 Methods of reducing the risk of cardiovascular events in a subject

Publications (1)

Publication Number Publication Date
BR112021005580A2 true BR112021005580A2 (pt) 2021-06-29

Family

ID=69884391

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021005580-0A BR112021005580A2 (pt) 2018-09-24 2019-04-22 usos de éster etílico de ácido eicosapentaenoico (e-epa) para reduzir o risco de eventos cardiovasculares em um indivíduo

Country Status (28)

Country Link
US (10) US10668042B2 (https=)
EP (4) EP3700518A4 (https=)
JP (3) JP7020756B2 (https=)
KR (4) KR20210110890A (https=)
CN (2) CN111991386A (https=)
AU (7) AU2019349563B2 (https=)
BR (1) BR112021005580A2 (https=)
CL (3) CL2021000645A1 (https=)
CY (1) CY1127011T1 (https=)
DK (3) DK3750536T3 (https=)
ES (3) ES3062006T3 (https=)
FI (3) FI3750535T3 (https=)
HR (2) HRP20240898T1 (https=)
HU (1) HUE067138T2 (https=)
IL (1) IL279494A (https=)
LT (3) LT4056176T (https=)
MA (3) MA50490A (https=)
MX (2) MX2021002553A (https=)
NI (1) NI202100014A (https=)
PL (2) PL3750535T3 (https=)
PT (1) PT4056176T (https=)
RS (2) RS65750B1 (https=)
SG (1) SG11202102872QA (https=)
SI (1) SI4056176T1 (https=)
SM (1) SMT202400320T1 (https=)
TN (1) TN2021000013A1 (https=)
WO (1) WO2020068163A1 (https=)
ZA (2) ZA202007993B (https=)

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