ATE549014T1 - Prostaglandin-fettemulsion, verfahren zu ihrer herstellung, verfahren zu ihrer stabilisierung und emulgierendes mittel - Google Patents
Prostaglandin-fettemulsion, verfahren zu ihrer herstellung, verfahren zu ihrer stabilisierung und emulgierendes mittelInfo
- Publication number
- ATE549014T1 ATE549014T1 AT07806606T AT07806606T ATE549014T1 AT E549014 T1 ATE549014 T1 AT E549014T1 AT 07806606 T AT07806606 T AT 07806606T AT 07806606 T AT07806606 T AT 07806606T AT E549014 T1 ATE549014 T1 AT E549014T1
- Authority
- AT
- Austria
- Prior art keywords
- fat emulsion
- stabilizing
- producing
- emulsifying agent
- prostaglandin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006240572 | 2006-09-05 | ||
PCT/JP2007/067133 WO2008029763A1 (fr) | 2006-09-05 | 2007-09-03 | Émulsion grasse de prostaglandine, son procédé de fabrication, son procédé de stabilisation et agent émulsifiant |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE549014T1 true ATE549014T1 (de) | 2012-03-15 |
Family
ID=39157190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07806606T ATE549014T1 (de) | 2006-09-05 | 2007-09-03 | Prostaglandin-fettemulsion, verfahren zu ihrer herstellung, verfahren zu ihrer stabilisierung und emulgierendes mittel |
Country Status (9)
Country | Link |
---|---|
US (1) | US8334321B2 (de) |
EP (1) | EP2065043B1 (de) |
JP (1) | JP5193870B2 (de) |
KR (1) | KR101411758B1 (de) |
CN (1) | CN101511367B (de) |
AT (1) | ATE549014T1 (de) |
RU (1) | RU2470644C2 (de) |
TW (1) | TWI403515B (de) |
WO (1) | WO2008029763A1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009093650A1 (ja) * | 2008-01-24 | 2009-07-30 | Techno Guard Co. Ltd. | プロスタグランジン含有脂肪乳剤およびその製造方法 |
EP2692360A4 (de) * | 2011-03-31 | 2014-10-29 | Fujifilm Corp | Prostaglandinhaltige fettemulsion |
CN105012248B (zh) * | 2014-04-29 | 2018-01-02 | 北京蓝丹医药科技有限公司 | 一种注射用前列地尔脂肪乳及其制备方法 |
CN105310976B (zh) * | 2014-06-04 | 2018-08-21 | 北京蓝丹医药科技有限公司 | 一种稳定的前列地尔组合物 |
CN106389328B (zh) * | 2015-07-31 | 2019-07-23 | 北京蓝丹医药科技有限公司 | 一种注射用前列地尔脂肪乳 |
CN107412160B (zh) * | 2016-05-24 | 2021-03-23 | 四川科伦药物研究院有限公司 | 一种含前列腺素的脂肪乳剂及其制备方法 |
CN108653208A (zh) * | 2017-03-30 | 2018-10-16 | 北京蓝丹医药科技有限公司 | 一种前列地尔注射液 |
CN110934829B (zh) * | 2019-12-30 | 2021-10-01 | 辅必成(上海)医药科技有限公司 | 一种阿瑞吡坦的纳米胶束 |
WO2023146984A1 (en) * | 2022-01-26 | 2023-08-03 | Amarin Pharmaceuticals Ireland Limited | Lymph-releasing compositions of fatty acids and uses thereof for lymphatic incorporation and systemic disease treatment |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
JPS58222014A (ja) | 1982-06-18 | 1983-12-23 | Taisho Pharmaceut Co Ltd | プロスタグランジンe↓1脂肪乳剤 |
JPS59216820A (ja) | 1983-05-20 | 1984-12-06 | Taisho Pharmaceut Co Ltd | プロスタグランジン脂肪乳剤 |
JPH0818989B2 (ja) * | 1984-01-12 | 1996-02-28 | 株式会社ミドリ十字 | 脂肪乳剤中のプロスタグランジンの安定化方法 |
US5082664A (en) * | 1987-05-22 | 1992-01-21 | The Liposome Company, Inc. | Prostaglandin-lipid formulations |
US5262168A (en) * | 1987-05-22 | 1993-11-16 | The Liposome Company, Inc. | Prostaglandin-lipid formulations |
JP2602964B2 (ja) | 1989-10-16 | 1997-04-23 | 裕 水島 | プロスタグランジン類縁体およびその脂肪乳剤 |
US5194670A (en) | 1989-10-16 | 1993-03-16 | Yutaka Mizushima, Asahi Glass Company Ltd. | Emulsion of lipid containing a prostaglandin analogue |
WO1992004886A1 (en) | 1990-09-26 | 1992-04-02 | Meito Sangyo Co., Ltd. | Fat emulsion for intravenous injection |
JPH04356417A (ja) | 1990-09-26 | 1992-12-10 | Kao Corp | 静脈注射用脂肪乳剤 |
JPH04338333A (ja) | 1991-05-13 | 1992-11-25 | Asahi Chem Ind Co Ltd | プロスタグランジンe1脂肪乳剤 |
JPH05139977A (ja) | 1991-05-17 | 1993-06-08 | Green Cross Corp:The | プロスタグランジン類リポソーム複合体を充填した注射器 |
JPH0769878A (ja) | 1993-06-28 | 1995-03-14 | Otsuka Pharmaceut Factory Inc | アミノ酸加脂肪乳剤 |
GB9501286D0 (en) * | 1995-01-24 | 1995-03-15 | Ciba Geigy Ag | Pharmaceutical compositions and preparations thereof |
US6214375B1 (en) | 1996-07-16 | 2001-04-10 | Generex Pharmaceuticals, Inc. | Phospholipid formulations |
EP1189597A4 (de) | 1999-06-04 | 2008-06-18 | Pacira Pharmaceuticals Inc | Zusammensetzungen mit einem öl-kern zur verzögerten freisetzung hydrophober arzneistoffe |
JP4421699B2 (ja) | 1999-06-30 | 2010-02-24 | 大洋薬品工業株式会社 | 静脈注射可能なプロスタグランジン脂肪乳剤 |
WO2003013513A1 (en) | 2001-08-03 | 2003-02-20 | Takeda Chemical Industries, Ltd. | Stable emulsion composition |
WO2004032980A1 (en) | 2002-10-04 | 2004-04-22 | Elan Pharma International Limited | Gamma irradiation of solid nanoparticulate active agents |
US20060134145A1 (en) | 2002-12-06 | 2006-06-22 | Otsuka Pharmaceutical Factory, Inc. | Propofol-containing fat emulsions |
-
2007
- 2007-09-03 RU RU2009112547/15A patent/RU2470644C2/ru not_active IP Right Cessation
- 2007-09-03 AT AT07806606T patent/ATE549014T1/de active
- 2007-09-03 WO PCT/JP2007/067133 patent/WO2008029763A1/ja active Application Filing
- 2007-09-03 JP JP2008533146A patent/JP5193870B2/ja active Active
- 2007-09-03 EP EP07806606A patent/EP2065043B1/de not_active Not-in-force
- 2007-09-03 KR KR1020097002802A patent/KR101411758B1/ko active IP Right Grant
- 2007-09-03 US US12/310,743 patent/US8334321B2/en active Active
- 2007-09-03 CN CN2007800327420A patent/CN101511367B/zh active Active
- 2007-09-05 TW TW096133130A patent/TWI403515B/zh active
Also Published As
Publication number | Publication date |
---|---|
RU2470644C2 (ru) | 2012-12-27 |
EP2065043B1 (de) | 2012-03-14 |
JPWO2008029763A1 (ja) | 2010-01-21 |
KR101411758B1 (ko) | 2014-06-25 |
JP5193870B2 (ja) | 2013-05-08 |
EP2065043A1 (de) | 2009-06-03 |
TWI403515B (zh) | 2013-08-01 |
KR20090064526A (ko) | 2009-06-19 |
CN101511367B (zh) | 2011-08-17 |
CN101511367A (zh) | 2009-08-19 |
TW200817423A (en) | 2008-04-16 |
US8334321B2 (en) | 2012-12-18 |
RU2009112547A (ru) | 2010-10-20 |
EP2065043A4 (de) | 2011-07-06 |
WO2008029763A1 (fr) | 2008-03-13 |
US20100112066A1 (en) | 2010-05-06 |
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