BR112018001660A2 - células exterminadoras naturais e linhagens de células exterminadoras naturais modificadas possuindo citotoxicidade aumentada - Google Patents

células exterminadoras naturais e linhagens de células exterminadoras naturais modificadas possuindo citotoxicidade aumentada

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Publication number
BR112018001660A2
BR112018001660A2 BR112018001660-8A BR112018001660A BR112018001660A2 BR 112018001660 A2 BR112018001660 A2 BR 112018001660A2 BR 112018001660 A BR112018001660 A BR 112018001660A BR 112018001660 A2 BR112018001660 A2 BR 112018001660A2
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BR
Brazil
Prior art keywords
natural killer
cell lines
cells
modified
increased cytotoxicity
Prior art date
Application number
BR112018001660-8A
Other languages
English (en)
Portuguese (pt)
Inventor
Eamon Peter O'dwyer Michael
Original Assignee
Onkimmune Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1603655.0A external-priority patent/GB201603655D0/en
Priority claimed from GBGB1610164.4A external-priority patent/GB201610164D0/en
Application filed by Onkimmune Limited filed Critical Onkimmune Limited
Publication of BR112018001660A2 publication Critical patent/BR112018001660A2/pt

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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
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    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
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    • A61K2239/27—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by targeting or presenting multiple antigens
    • A61K2239/29—Multispecific CARs
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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BR112018001660-8A 2015-07-29 2016-07-28 células exterminadoras naturais e linhagens de células exterminadoras naturais modificadas possuindo citotoxicidade aumentada BR112018001660A2 (pt)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP15178899.9 2015-07-29
EP15178899 2015-07-29
GB1603655.0 2016-03-02
GBGB1603655.0A GB201603655D0 (en) 2016-03-02 2016-03-02 Modified natural killer cells and natural killer cell lines having increased cytotoxicity
GB201605457 2016-03-31
GB1605457.9 2016-03-31
GBGB1610164.4A GB201610164D0 (en) 2016-06-10 2016-06-10 Modified natural killer cells and natural killer cell lines having increased cytoxicity
GB1610164.4 2016-06-10
PCT/EP2016/068001 WO2017017184A1 (en) 2015-07-29 2016-07-28 Modified natural killer cells and natural killer cell lines having increased cytotoxicity

Publications (1)

Publication Number Publication Date
BR112018001660A2 true BR112018001660A2 (pt) 2018-09-18

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BR112018001660-8A BR112018001660A2 (pt) 2015-07-29 2016-07-28 células exterminadoras naturais e linhagens de células exterminadoras naturais modificadas possuindo citotoxicidade aumentada

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US (3) US10034925B2 (enExample)
EP (6) EP3971284B1 (enExample)
JP (3) JP6974681B2 (enExample)
KR (1) KR20180028530A (enExample)
CN (3) CN108026512B (enExample)
AU (2) AU2016300128B2 (enExample)
BR (1) BR112018001660A2 (enExample)
CA (2) CA3156128A1 (enExample)
DK (3) DK3421590T3 (enExample)
ES (5) ES2970269T3 (enExample)
HK (1) HK1252582B (enExample)
MX (2) MX380813B (enExample)
WO (1) WO2017017184A1 (enExample)

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