MY185817A - Methods for production of oxygenated terpenes - Google Patents

Methods for production of oxygenated terpenes

Info

Publication number
MY185817A
MY185817A MYPI2017700561A MYPI2017700561A MY185817A MY 185817 A MY185817 A MY 185817A MY PI2017700561 A MYPI2017700561 A MY PI2017700561A MY PI2017700561 A MYPI2017700561 A MY PI2017700561A MY 185817 A MY185817 A MY 185817A
Authority
MY
Malaysia
Prior art keywords
methods
production
oxygenated terpenes
terpenes
oxygenated
Prior art date
Application number
MYPI2017700561A
Inventor
Ajikumar Parayil Kumaran
Chin Giaw Lim
Liwei Li
Souvik Ghosh
Christopher Pirie
Anthony Qualley
Original Assignee
Manus Biosynthesis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Manus Biosynthesis Inc filed Critical Manus Biosynthesis Inc
Publication of MY185817A publication Critical patent/MY185817A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/24Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26Ketones
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N27/00Biocides, pest repellants or attractants, or plant growth regulators containing hydrocarbons
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/10Natural spices, flavouring agents or condiments; Extracts thereof
    • A23L27/12Natural spices, flavouring agents or condiments; Extracts thereof from fruit, e.g. essential oils
    • A23L27/13Natural spices, flavouring agents or condiments; Extracts thereof from fruit, e.g. essential oils from citrus fruits
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0073Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen 1.14.13
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/002Preparation of hydrocarbons or halogenated hydrocarbons cyclic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/13Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen (1.14.13)
    • C12Y114/13078Ent-kaurene oxidase (1.14.13.78)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment

Abstract

The present invention relates to methods for producing oxygenated terpenoids. Polynucleotides, derivative enzymes, and host cells for use in such methods are also provided.
MYPI2017700561A 2014-08-21 2015-08-21 Methods for production of oxygenated terpenes MY185817A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462040284P 2014-08-21 2014-08-21
PCT/US2015/046369 WO2016029153A1 (en) 2014-08-21 2015-08-21 Methods for production of oxygenated terpenes

Publications (1)

Publication Number Publication Date
MY185817A true MY185817A (en) 2021-06-10

Family

ID=54035332

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2017700561A MY185817A (en) 2014-08-21 2015-08-21 Methods for production of oxygenated terpenes

Country Status (7)

Country Link
US (5) US10934564B2 (en)
EP (2) EP3183353A2 (en)
JP (1) JP6735750B2 (en)
CN (1) CN107002109A (en)
MY (1) MY185817A (en)
SG (1) SG11201701278RA (en)
WO (2) WO2016029187A2 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY185817A (en) * 2014-08-21 2021-06-10 Manus Biosynthesis Inc Methods for production of oxygenated terpenes
ES2959560T3 (en) * 2015-08-21 2024-02-27 Manus Bio Inc Increased productivity of E. coli host cells that functionally express P450 enzymes
BR112019000892A2 (en) * 2016-07-20 2019-04-30 Firmenich & Cie vetiver
JP7187445B2 (en) 2016-09-16 2022-12-12 ペプシコ・インク Compositions and methods for improving the taste of non-nutritive sweeteners
WO2018082588A1 (en) * 2016-11-04 2018-05-11 中国科学院天津工业生物技术研究所 Recombinant yeast and use thereof
CA3051472A1 (en) 2017-01-26 2018-08-02 Manus Bio, Inc. Metabolic engineering for microbial production of terpenoid products
CA3051463A1 (en) 2017-02-03 2018-08-09 Manus Bio, Inc. Metabolic engineering for microbial production of terpenoid products
CN107723252A (en) * 2017-09-22 2018-02-23 天津大学 Produce the restructuring Yarrowia lipolytica and construction method of valencia orange alkene and nootkatone
WO2019059337A1 (en) * 2017-09-22 2019-03-28 味の素株式会社 Nootkatone production method
BR112020010924A2 (en) * 2018-01-18 2020-11-17 Firmenich S.A. cytochrome p450 monooxygenase catalyzed oxidation of sesquiterpenes
MX2020008922A (en) * 2018-02-27 2021-01-08 Manus Bio Inc Microbial production of triterpenoids including mogrosides.
WO2019194287A1 (en) 2018-04-06 2019-10-10 味の素株式会社 Method for producing 13-hydroxy-9(z)-octadecenoic acid
GB201808663D0 (en) * 2018-05-25 2018-07-11 Innes John Centre Method
CN113195726A (en) * 2018-09-06 2021-07-30 马努斯生物合成股份有限公司 Microbial production of cyperolone
EP3861101A4 (en) * 2018-10-05 2022-07-20 Manus Bio Inc. Biosynthesis and recovery of secondary metabolites
CN109486695B (en) * 2018-12-26 2021-04-06 浙江医药股份有限公司 Yarrowia lipolytica for farnesene production
CN109913380B (en) * 2019-03-25 2021-12-10 南京工业大学 Recombinant yarrowia lipolytica for producing (-) -alpha-bisabolol and construction method and application thereof
CN110923249A (en) * 2019-10-15 2020-03-27 贵州省烟草科学研究院 Tobacco CyP71 and application thereof in regulation and control of plant epidermal hair development
CN111019852B (en) * 2019-12-31 2021-11-23 江南大学 Method for improving efficiency of synthesizing glucaric acid by saccharomyces cerevisiae engineering strain
CN111154665B (en) * 2020-01-21 2021-02-02 南京工业大学 Recombinant yarrowia lipolytica and construction method and application thereof
CN111235046A (en) * 2020-02-05 2020-06-05 天津大学 Recombinant yarrowia lipolytica for heterologous synthesis of α -santalene and construction method thereof
US20210292797A1 (en) * 2020-03-23 2021-09-23 The Regents Of The University Of California Fusion proteins useful for modifying terpenes
CN111394290A (en) * 2020-03-26 2020-07-10 北京化工大学 Gene engineering bacterium for producing longifolene and construction method and application thereof
BR112023005529A2 (en) 2020-10-30 2023-05-09 Givaudan Sa METHOD TO REDUCE THE CONVERSION OF VOLATILE TERPENE SPECIES
KR20230098262A (en) 2020-10-30 2023-07-03 지보당 에스아 Methods that cause conversion of volatile terpene species
CN112391360B (en) * 2020-11-04 2022-09-06 江南大学 Flavone 3 beta-hydroxylase reductase mutant and application thereof
EP4337768A1 (en) * 2021-05-11 2024-03-20 Manus Bio Inc. Enzymes, host cells, and methods for production of rotundone and other terpenoids
CN114181964B (en) * 2021-11-02 2023-06-09 云南大学 Expression cassette combination, recombinant vector, recombinant saccharomyces cerevisiae and application of recombinant saccharomyces cerevisiae
CN114480512B (en) * 2021-12-13 2022-10-25 华南理工大学 Application of oxidoreductase and mutant thereof in biosynthesis of nootkatone

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9607301A (en) * 1995-12-18 1997-11-25 Firmenich & Cie Process for the preparation of nootkatone or nootkatol
EP1033076A4 (en) 1997-11-17 2001-04-11 Taisho Pharmaceutical Co Ltd Hematophagous insect repellent
GB9825421D0 (en) 1998-11-19 1999-01-13 Isis Innovation Process for oxidising terpenes
US6200786B1 (en) 1999-09-08 2001-03-13 Givaudan S.A. Process for the preparation of nootkatone by laccase catalysis
US6890960B1 (en) 1999-10-19 2005-05-10 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Vetiver oil extracts as termite repellent and toxicant
US7172886B2 (en) 2001-12-06 2007-02-06 The Regents Of The University Of California Biosynthesis of isopentenyl pyrophosphate
JP4139646B2 (en) 2002-08-01 2008-08-27 長谷川香料株式会社 Aroma flavoring agent
ATE546521T1 (en) 2002-10-04 2012-03-15 Firmenich & Cie SESQUITERPENE SYNTHASES AND METHODS OF USE
CN1703507B (en) * 2002-10-04 2010-09-29 弗门尼舍有限公司 Sesquiterpene synthases and methods of use
CA2535526C (en) 2003-08-11 2015-09-29 Diversa Corporation Laccases, nucleic acids encoding them and methods for making and using them
DE102004006825A1 (en) 2004-02-11 2005-09-01 Maxens Gmbh Process for the preparation of aroma-active terpenes
WO2006079020A2 (en) * 2005-01-19 2006-07-27 University Of Kentucky Research Foundation Functional identification of the hyoscyamus muticus gene coding for premnaspirodiene hydroxylase activity
MY162232A (en) 2009-11-10 2017-05-31 Massachusetts Inst Technology Microbial engineering for the production of chemical and pharmaceutical products from the isoprenoid pathway
US8927241B2 (en) 2009-11-10 2015-01-06 Massachusetts Institute Of Technology Microbial engineering for the production of chemical and pharmaceutical products from the isoprenoid pathway
EP2633042A1 (en) 2010-10-29 2013-09-04 Allylix, Inc. Modified valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
CA2819253A1 (en) 2010-11-30 2012-06-07 Massachusetts Institute Of Technology Microbial production of natural sweeteners, diterpenoid steviol glycosides
JP6073350B2 (en) 2011-11-09 2017-02-01 アミリス, インコーポレイテッド Production of acetyl-coenzyme A-induced isoprenoids
EP2914729B1 (en) * 2012-11-01 2022-01-26 The University of British Columbia Cytochrome p450 and cytochrome p450 reductase polypeptides, encoding nucleic acid molecules and uses thereof
KR101559489B1 (en) 2014-04-08 2015-10-12 한국해양과학기술원 Yaw control type tidal stream generator by rudder and yaw control method of the same
MY185817A (en) 2014-08-21 2021-06-10 Manus Biosynthesis Inc Methods for production of oxygenated terpenes
WO2016073740A1 (en) 2014-11-05 2016-05-12 Manus Biosynthesis, Inc. Microbial production of steviol glycosides
ES2959560T3 (en) 2015-08-21 2024-02-27 Manus Bio Inc Increased productivity of E. coli host cells that functionally express P450 enzymes
CN113195726A (en) * 2018-09-06 2021-07-30 马努斯生物合成股份有限公司 Microbial production of cyperolone

Also Published As

Publication number Publication date
EP3183357A1 (en) 2017-06-28
EP3183353A2 (en) 2017-06-28
SG11201701278RA (en) 2017-03-30
JP2017525395A (en) 2017-09-07
JP6735750B2 (en) 2020-08-05
US20220073955A1 (en) 2022-03-10
US10501760B2 (en) 2019-12-10
US20180327789A1 (en) 2018-11-15
WO2016029153A1 (en) 2016-02-25
US20200224224A1 (en) 2020-07-16
EP3183357B1 (en) 2020-03-04
US11180782B2 (en) 2021-11-23
US20210292798A1 (en) 2021-09-23
WO2016029187A2 (en) 2016-02-25
US10934564B2 (en) 2021-03-02
US20180135081A1 (en) 2018-05-17
US11807890B2 (en) 2023-11-07
CN107002109A (en) 2017-08-01
WO2016029187A3 (en) 2016-05-06
EP3183357A4 (en) 2018-07-04

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