DK3421590T3 - Modificerede naturlige dræberceller og naturlige dræbercellelinjer med øget cytotoksicitet - Google Patents

Modificerede naturlige dræberceller og naturlige dræbercellelinjer med øget cytotoksicitet Download PDF

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Publication number
DK3421590T3
DK3421590T3 DK18187137.7T DK18187137T DK3421590T3 DK 3421590 T3 DK3421590 T3 DK 3421590T3 DK 18187137 T DK18187137 T DK 18187137T DK 3421590 T3 DK3421590 T3 DK 3421590T3
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Prior art keywords
natural killer
cell lines
increased cytotoxicity
killer cells
modified
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DK18187137.7T
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Michael Eamon Peter O'dwyer
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Onk Therapeutics Ltd
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Priority claimed from GBGB1603655.0A external-priority patent/GB201603655D0/en
Priority claimed from GBGB1610164.4A external-priority patent/GB201610164D0/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/4613—Natural-killer cells [NK or NK-T]
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    • C12N5/0646—Natural killers cells [NK], NKT cells
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    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/48—Regulators of apoptosis
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
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    • C12R2001/00—Microorganisms ; Processes using microorganisms
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  • Pharmacology & Pharmacy (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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DK18187137.7T 2015-07-29 2016-07-28 Modificerede naturlige dræberceller og naturlige dræbercellelinjer med øget cytotoksicitet DK3421590T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP15178899 2015-07-29
GBGB1603655.0A GB201603655D0 (en) 2016-03-02 2016-03-02 Modified natural killer cells and natural killer cell lines having increased cytotoxicity
GB201605457 2016-03-31
GBGB1610164.4A GB201610164D0 (en) 2016-06-10 2016-06-10 Modified natural killer cells and natural killer cell lines having increased cytoxicity
EP16750677.3A EP3317401B1 (en) 2015-07-29 2016-07-28 Modified natural killer cells and natural killer cell lines having increased cytotoxicity

Publications (1)

Publication Number Publication Date
DK3421590T3 true DK3421590T3 (da) 2021-10-04

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Application Number Title Priority Date Filing Date
DK18187137.7T DK3421590T3 (da) 2015-07-29 2016-07-28 Modificerede naturlige dræberceller og naturlige dræbercellelinjer med øget cytotoksicitet
DK16750677.3T DK3317401T3 (da) 2015-07-29 2016-07-28 Modificerede naturlige dræberceller og naturlige dræbercellelinjer med øget cytotoksicitet
DK18194107.1T DK3434762T3 (da) 2015-07-29 2016-07-28 Modificerede, naturlige dræberceller og naturlige dræbercellelinjer med øget cytotoksicitet

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DK16750677.3T DK3317401T3 (da) 2015-07-29 2016-07-28 Modificerede naturlige dræberceller og naturlige dræbercellelinjer med øget cytotoksicitet
DK18194107.1T DK3434762T3 (da) 2015-07-29 2016-07-28 Modificerede, naturlige dræberceller og naturlige dræbercellelinjer med øget cytotoksicitet

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US (3) US10034925B2 (da)
EP (6) EP3421590B1 (da)
JP (3) JP6974681B2 (da)
KR (1) KR20180028530A (da)
CN (3) CN116064401A (da)
AU (2) AU2016300128B2 (da)
BR (1) BR112018001660A2 (da)
CA (2) CA3156128A1 (da)
DK (3) DK3421590T3 (da)
ES (5) ES2876938T3 (da)
HK (1) HK1252582B (da)
MX (2) MX2018001074A (da)
WO (1) WO2017017184A1 (da)

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JP2021178824A (ja) 2021-11-18
AU2016300128B2 (en) 2022-03-17
EP3971284A1 (en) 2022-03-23
EP3828266A1 (en) 2021-06-02
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AU2022203339A1 (en) 2022-06-09
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JP2021169473A (ja) 2021-10-28
US20210138051A1 (en) 2021-05-13
KR20180028530A (ko) 2018-03-16
US20180326029A1 (en) 2018-11-15
CN116064400A (zh) 2023-05-05
ES2890859T3 (es) 2022-01-24
DK3317401T3 (da) 2019-01-02
ES2701338T3 (es) 2019-02-21
CA3156128A1 (en) 2017-02-02
AU2016300128A1 (en) 2018-02-22
CN108026512A (zh) 2018-05-11
MX2018001074A (es) 2018-11-12
ES2876938T3 (es) 2021-11-15
EP3421590B1 (en) 2021-07-14
CN108026512B (zh) 2022-09-16
JP6974681B2 (ja) 2021-12-01
EP3828266B1 (en) 2022-11-23
US20170157230A1 (en) 2017-06-08
CA2993796A1 (en) 2017-02-02
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HK1252582B (zh) 2020-02-07
HK1252582A1 (zh) 2019-05-31
RU2018104871A3 (da) 2020-08-17
DK3434762T3 (da) 2021-06-07
EP3317401A1 (en) 2018-05-09
EP3434762A1 (en) 2019-01-30
RU2018104871A (ru) 2019-08-28
US10034925B2 (en) 2018-07-31
ES2939084T3 (es) 2023-04-18
EP3421590A1 (en) 2019-01-02
EP3317401B1 (en) 2018-10-03
WO2017017184A1 (en) 2017-02-02
EP3434762B1 (en) 2021-03-17
JP2018522592A (ja) 2018-08-16
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BR112018001660A2 (pt) 2018-09-18
US10960064B2 (en) 2021-03-30

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