BR112016017592A2 - Microrganismos que apresentam produtividade aumentada de l-aminoácidos e processo para produção de l-aminoácidos utilizando estes - Google Patents

Microrganismos que apresentam produtividade aumentada de l-aminoácidos e processo para produção de l-aminoácidos utilizando estes

Info

Publication number
BR112016017592A2
BR112016017592A2 BR112016017592A BR112016017592A BR112016017592A2 BR 112016017592 A2 BR112016017592 A2 BR 112016017592A2 BR 112016017592 A BR112016017592 A BR 112016017592A BR 112016017592 A BR112016017592 A BR 112016017592A BR 112016017592 A2 BR112016017592 A2 BR 112016017592A2
Authority
BR
Brazil
Prior art keywords
amino acids
production
organisms
micro
increased productivity
Prior art date
Application number
BR112016017592A
Other languages
English (en)
Other versions
BR112016017592B1 (pt
Inventor
Sung Koh Eun
Yon Kwon Su
Ho Lee Kwang
Sun Lee Ji
Jang Juno
Cheol Lee Keun
Pyo Hong Hyeong
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of BR112016017592A2 publication Critical patent/BR112016017592A2/pt
Publication of BR112016017592B1 publication Critical patent/BR112016017592B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227—Tryptophan
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/26—Processes using, or culture media containing, hydrocarbons
    • C12N1/28—Processes using, or culture media containing, hydrocarbons aliphatic
    • C12N1/30—Processes using, or culture media containing, hydrocarbons aliphatic having five or less carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2497—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing N- glycosyl compounds (3.2.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/02—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2) hydrolysing N-glycosyl compounds (3.2.2)
    • C12Y302/02004—AMP nucleosidase (3.2.2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/04—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amidines (3.5.4)
    • C12Y305/04004—Adenosine deaminase (3.5.4.4)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

MICRORGANISMOS QUE APRESENTAM PRODUTIVIDADE AUMENTADA DE L-AMINOÁCIDOS E PROCESSO PARA PRODUÇÃO DE L-AMINOÁCIDOS UTILIZANDO ESTES. A presente invenção descreve um microrganismo recombinante com produtividade aumentada do L-aminoácido, em que o microrganismo recombinante é transformado para remover ou diminuir a atividade de no mínimo uma adenosina deaminase e AMP nucleosidase, e um método de produção de um L-aminoácido utilizando este microrganismo. O uso do microrganismo recombinante pode permitir a produção do L-aminoácido de uma forma mais eficiente.
BR112016017592-1A 2014-03-21 2015-03-17 Microrganismo recombinante e método de produção de laminoácidos BR112016017592B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020140033698A KR101599800B1 (ko) 2014-03-21 2014-03-21 Ｌ-아미노산의 생산능이 향상된 미생물 및 이를 이용하여 ｌ-아미노산을 생산하는 방법
KR10-2014-0033698 2014-03-21
PCT/KR2015/002551 WO2015142021A1 (en) 2014-03-21 2015-03-17 Microorganisms having enhanced l-amino acids productivity and process for producing l-amino acids using the same

Publications (2)

Publication Number Publication Date
BR112016017592A2 true BR112016017592A2 (pt) 2017-10-03
BR112016017592B1 BR112016017592B1 (pt) 2023-11-14

Family

ID=54144919

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016017592-1A BR112016017592B1 (pt) 2014-03-21 2015-03-17 Microrganismo recombinante e método de produção de laminoácidos

Country Status (16)

Country Link
US (1) US10113191B2 (pt)
EP (1) EP3119874B1 (pt)
JP (1) JP6494643B2 (pt)
KR (1) KR101599800B1 (pt)
CN (1) CN105980545B (pt)
AR (1) AR099811A1 (pt)
BR (1) BR112016017592B1 (pt)
DK (1) DK3119874T3 (pt)
ES (1) ES2728970T3 (pt)
HU (1) HUE045306T2 (pt)
MY (1) MY180267A (pt)
PL (1) PL3119874T3 (pt)
TR (1) TR201907655T4 (pt)
TW (2) TW201734199A (pt)
UA (1) UA118276C2 (pt)
WO (1) WO2015142021A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116254242B (zh) * 2022-12-21 2024-01-30 江南大学 一种atp磷酸核苷转移酶突变体及产l-组氨酸的谷氨酸棒杆菌

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100697551B1 (ko) * 1997-07-18 2007-03-21 아지노모토 가부시키가이샤 발효에 의한 퓨린 뉴클레오사이드의 제조 방법
KR100270510B1 (ko) 1998-08-14 2000-11-01 고두모 신규 미생물 및 이를 이용한 엘- 쓰레오닌의 제조방법
RU2175351C2 (ru) * 1998-12-30 2001-10-27 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО "АГРИ") Фрагмент днк из escherichia coli, определяющий повышенную продукцию l-аминокислот (варианты), и способ получения l-аминокислот
WO2002097086A1 (fr) * 2001-05-29 2002-12-05 Kyowa Hakko Kogyo Co., Ltd. Micro-organismes utiles a echelle industrielle
KR100792095B1 (ko) * 2006-12-29 2008-01-04 씨제이 주식회사 Ｌ-페닐알라닌 생산능을 갖는 대장균 변이주로부터유전자조작된 ｌ-트립토판 생산능을 갖는 재조합 대장균균주 및 이를 이용한 트립토판 제조방법
KR100966324B1 (ko) 2008-01-08 2010-06-28 씨제이제일제당 (주) 향상된 ｌ－쓰레오닌 생산능을 갖는 대장균 및 이를 이용한ｌ－쓰레오닌의 생산 방법
EP2264144A4 (en) 2008-02-25 2012-11-07 Ajinomoto Kk PROCESS FOR THE PREPARATION OF 5'-GUANYLIC ACID
CA2753495C (en) * 2009-02-26 2018-05-15 Advanced Cooling Therapy, Llc Devices and methods for controlling patient temperature
KR101261147B1 (ko) 2011-01-18 2013-05-06 씨제이제일제당 (주) Ｌ-아미노산의 생산능이 향상된 미생물 및 이를 이용하여 ｌ-아미노산을 생산하는 방법
KR101327093B1 (ko) 2012-01-06 2013-11-07 씨제이제일제당 (주) Ｌ-아미노산을 생산할 수 있는 미생물 및 이를 이용하여 ｌ-아미노산을 생산하는 방법

Also Published As

Publication number Publication date
WO2015142021A1 (en) 2015-09-24
TW201734199A (zh) 2017-10-01
US10113191B2 (en) 2018-10-30
DK3119874T3 (da) 2019-07-22
JP2017504349A (ja) 2017-02-09
TW201538725A (zh) 2015-10-16
KR101599800B1 (ko) 2016-03-04
TWI639698B (zh) 2018-11-01
EP3119874A1 (en) 2017-01-25
MY180267A (en) 2020-11-26
EP3119874B1 (en) 2019-05-08
TR201907655T4 (tr) 2019-06-21
AR099811A1 (es) 2016-08-17
BR112016017592B1 (pt) 2023-11-14
ES2728970T3 (es) 2019-10-29
CN105980545A (zh) 2016-09-28
PL3119874T3 (pl) 2019-10-31
US20170002388A1 (en) 2017-01-05
KR20150109990A (ko) 2015-10-02
UA118276C2 (uk) 2018-12-26
EP3119874A4 (en) 2017-11-15
JP6494643B2 (ja) 2019-04-03
HUE045306T2 (hu) 2019-12-30
CN105980545B (zh) 2019-12-24

Similar Documents

Publication Publication Date Title
BR112016023814A2 (pt) mutações visadas
BR112017023189A2 (pt) aparelho de efeito de campo e métodos para sequenciar ácidos nucleicos
BR112017013748A2 (pt) método de produção & processamento de diaminas
BR112019000718A2 (pt) processo para a produção de geopolímero ou compósito de geopolímero
GB2544001A (en) Methods for increasing Cas9-mediated engineering efficiency
BR112017013691A2 (pt) composição compreendendo um polímero em multiestágio, seu método de preparação e seu uso
WO2015196128A3 (en) Alternative nucleic acid molecules and uses thereof
WO2015196130A3 (en) Alternative nucleic acid molecules and uses thereof
PH12016501222A1 (en) Post-drive summary with tutorial
BR112016025792A2 (pt) meios e processos para tratamento de cmv
BR112013018385A2 (pt) microorganismo com produtividade de l-aminoácidos aumentada e processo de produção de l-aminoácidos usando o mesmo
GB2537077A (en) Methods for sequencing nucleic acids
BR112017019057A2 (pt) ?variantes de piruvato desidrogenase, um micro- organismo que compreende as mesmas e um método para produzir l-aminoácido com o uso das mesmas?
BR112017000135A2 (pt) processo para a preparação de ácidos 4-alcóxi-3-hidroxipicolínico
CL2016000746A1 (es) Un método para producir un l-aminoácido usando una bacteria de la familia de las enterobacteriaceae teniendo atenuada la expresión de un gen que codifica un transportador de fosfato
BR112016029033A2 (pt) processo para a produção de ésteres de éter glicólico com baixo teor de voc
BR112018000074A2 (pt) micro-organismo para produzir l-lisina e método para produzir l-lisina com o uso do mesmo
HUE048849T2 (hu) Corynebacterium nemzetségbe tartozó mikroorganizmus L-aminosav elõállítására és eljárás L-aminosav elõállítására annak alkalmazásával
BR112017016895A2 (pt) processo de produção de gonadotrofina
BR112016030604B8 (pt) Processo para preparação de ácidos 3- hidroxipicolínicos
BR112016029035A2 (pt) processo para a produção de auxiliares de coalescência com baixo teor de voc
BR112016017281A2 (pt) microrganismos produtores de l-aminoácidos e processo para produção de l-aminoácidos usando os mesmos
BR112017008026A2 (pt) processos de produção de composições com melhor perfil de segurança que possui atividade de lipase e composições apropriadas para uso farmacêutico
BR112016027249A8 (pt) Processo para hidrólise de material lignocelulósico em que o hidrolisado é usado para produção de hidrolase microbiana
BR112016024970A2 (pt) microorganismos para produzir diamina e processo para produzir diamina usando os mesmos

Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 17/03/2015, OBSERVADAS AS CONDICOES LEGAIS