TR201907655T4 - Geliştirilmiş l-amino asit verimliliğine sahip mikroorganizmalar ve bunları kullanarak l-amino asitlerin üretilmesine yönelik proses. - Google Patents

Geliştirilmiş l-amino asit verimliliğine sahip mikroorganizmalar ve bunları kullanarak l-amino asitlerin üretilmesine yönelik proses. Download PDF

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Publication number
TR201907655T4
TR201907655T4 TR2019/07655T TR201907655T TR201907655T4 TR 201907655 T4 TR201907655 T4 TR 201907655T4 TR 2019/07655 T TR2019/07655 T TR 2019/07655T TR 201907655 T TR201907655 T TR 201907655T TR 201907655 T4 TR201907655 T4 TR 201907655T4
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Turkey
Prior art keywords
amino acid
improved
production
microorganisms
amino acids
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TR2019/07655T
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English (en)
Inventor
Sung Koh Eun
Yon Kwon Su
Ho Lee Kwang
Sun Lee Ji
Jang Juno
Cheol Lee Keun
Pyo Hong Hyeong
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Cj Cheiljedang Corp
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Publication of TR201907655T4 publication Critical patent/TR201907655T4/tr

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    • CCHEMISTRY; METALLURGY
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    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/22Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227Tryptophan
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    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/26Processes using, or culture media containing, hydrocarbons
    • C12N1/28Processes using, or culture media containing, hydrocarbons aliphatic
    • C12N1/30Processes using, or culture media containing, hydrocarbons aliphatic having five or less carbon atoms
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2497Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing N- glycosyl compounds (3.2.2)
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
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    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
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    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/02Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2) hydrolysing N-glycosyl compounds (3.2.2)
    • C12Y302/02004AMP nucleosidase (3.2.2.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y305/00Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/04Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amidines (3.5.4)
    • C12Y305/04004Adenosine deaminase (3.5.4.4)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
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  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
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  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Oil, Petroleum & Natural Gas (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Geliştirilmiş L-amino asit verimliliğine sahip bir rekombinant mikroorganizma, burada rekombinant mikroorganizma, adenozin deaminaz ve AMP nükleosidazın en az birinin giderilmiş veya azaltılmış aktivitesine sahip olmak için dönüştürülmektedir, ve rekombinant mikroorganizma kullanılarak bir L-amino asit üretmek için bir yöntem açıklanmaktadır. Rekombinant mikroorganizmanın kullanılması, oldukça etkili bir şekilde L-amino asit üretimi sağlayabilmektedir.
TR2019/07655T 2014-03-21 2015-03-17 Geliştirilmiş l-amino asit verimliliğine sahip mikroorganizmalar ve bunları kullanarak l-amino asitlerin üretilmesine yönelik proses. TR201907655T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020140033698A KR101599800B1 (ko) 2014-03-21 2014-03-21 L-아미노산의 생산능이 향상된 미생물 및 이를 이용하여 l-아미노산을 생산하는 방법

Publications (1)

Publication Number Publication Date
TR201907655T4 true TR201907655T4 (tr) 2019-06-21

Family

ID=54144919

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/07655T TR201907655T4 (tr) 2014-03-21 2015-03-17 Geliştirilmiş l-amino asit verimliliğine sahip mikroorganizmalar ve bunları kullanarak l-amino asitlerin üretilmesine yönelik proses.

Country Status (16)

Country Link
US (1) US10113191B2 (tr)
EP (1) EP3119874B1 (tr)
JP (1) JP6494643B2 (tr)
KR (1) KR101599800B1 (tr)
CN (1) CN105980545B (tr)
AR (1) AR099811A1 (tr)
BR (1) BR112016017592B1 (tr)
DK (1) DK3119874T3 (tr)
ES (1) ES2728970T3 (tr)
HU (1) HUE045306T2 (tr)
MY (1) MY180267A (tr)
PL (1) PL3119874T3 (tr)
TR (1) TR201907655T4 (tr)
TW (2) TWI639698B (tr)
UA (1) UA118276C2 (tr)
WO (1) WO2015142021A1 (tr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116254242B (zh) * 2022-12-21 2024-01-30 江南大学 一种atp磷酸核苷转移酶突变体及产l-组氨酸的谷氨酸棒杆菌

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100697552B1 (ko) * 1997-07-18 2007-03-21 아지노모토 가부시키가이샤 발효에 의한 퓨린 뉴클레오사이드의 제조 방법
KR100270510B1 (ko) * 1998-08-14 2000-11-01 고두모 신규 미생물 및 이를 이용한 엘- 쓰레오닌의 제조방법
RU2175351C2 (ru) * 1998-12-30 2001-10-27 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО "АГРИ") Фрагмент днк из escherichia coli, определяющий повышенную продукцию l-аминокислот (варианты), и способ получения l-аминокислот
JPWO2002097086A1 (ja) * 2001-05-29 2005-04-07 協和醗酵工業株式会社 工業的生産に有用な微生物
KR100792095B1 (ko) * 2006-12-29 2008-01-04 씨제이 주식회사 L-페닐알라닌 생산능을 갖는 대장균 변이주로부터유전자조작된 l-트립토판 생산능을 갖는 재조합 대장균균주 및 이를 이용한 트립토판 제조방법
KR100966324B1 (ko) * 2008-01-08 2010-06-28 씨제이제일제당 (주) 향상된 l-쓰레오닌 생산능을 갖는 대장균 및 이를 이용한l-쓰레오닌의 생산 방법
BRPI0907542A2 (pt) 2008-02-25 2015-07-28 Ajinomoto Kk Método para produzir ácido 5'-guanílico, e, microrganismo com uma capacidade de converter ácido inosínico em ácido 5'-guanílico
EP2401023B1 (en) * 2009-02-26 2016-04-20 Advanced Cooling Therapy, Inc. Devices for controlling patient temperature
KR101261147B1 (ko) * 2011-01-18 2013-05-06 씨제이제일제당 (주) L-아미노산의 생산능이 향상된 미생물 및 이를 이용하여 l-아미노산을 생산하는 방법
KR101327093B1 (ko) * 2012-01-06 2013-11-07 씨제이제일제당 (주) L-아미노산을 생산할 수 있는 미생물 및 이를 이용하여 l-아미노산을 생산하는 방법

Also Published As

Publication number Publication date
JP6494643B2 (ja) 2019-04-03
EP3119874A4 (en) 2017-11-15
WO2015142021A1 (en) 2015-09-24
MY180267A (en) 2020-11-26
HUE045306T2 (hu) 2019-12-30
JP2017504349A (ja) 2017-02-09
UA118276C2 (uk) 2018-12-26
TW201538725A (zh) 2015-10-16
KR101599800B1 (ko) 2016-03-04
CN105980545A (zh) 2016-09-28
DK3119874T3 (da) 2019-07-22
EP3119874A1 (en) 2017-01-25
US20170002388A1 (en) 2017-01-05
AR099811A1 (es) 2016-08-17
KR20150109990A (ko) 2015-10-02
ES2728970T3 (es) 2019-10-29
BR112016017592B1 (pt) 2023-11-14
CN105980545B (zh) 2019-12-24
BR112016017592A2 (pt) 2017-10-03
TW201734199A (zh) 2017-10-01
TWI639698B (zh) 2018-11-01
US10113191B2 (en) 2018-10-30
PL3119874T3 (pl) 2019-10-31
EP3119874B1 (en) 2019-05-08

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