BR112014004313A2 - composto glicosídeo, métodos de produção de um tioéter, de éter e de composto glicosídeo, e, éter. - Google Patents
composto glicosídeo, métodos de produção de um tioéter, de éter e de composto glicosídeo, e, éter.Info
- Publication number
- BR112014004313A2 BR112014004313A2 BR112014004313A BR112014004313A BR112014004313A2 BR 112014004313 A2 BR112014004313 A2 BR 112014004313A2 BR 112014004313 A BR112014004313 A BR 112014004313A BR 112014004313 A BR112014004313 A BR 112014004313A BR 112014004313 A2 BR112014004313 A2 BR 112014004313A2
- Authority
- BR
- Brazil
- Prior art keywords
- ether
- glycoside compound
- thioether
- producing
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/16—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by addition of hydrogen sulfide or its salts to unsaturated compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/12—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/067—Pyrimidine radicals with ribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/167—Purine radicals with ribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011184196 | 2011-08-25 | ||
PCT/JP2012/071517 WO2013027843A1 (ja) | 2011-08-25 | 2012-08-24 | 配糖体化合物、チオエーテルの製造方法、エーテル、エーテルの製造方法、配糖体化合物の製造方法、核酸の製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112014004313A2 true BR112014004313A2 (pt) | 2017-03-28 |
BR112014004313A8 BR112014004313A8 (pt) | 2023-02-07 |
Family
ID=47746578
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014004313A BR112014004313A8 (pt) | 2011-08-25 | 2012-08-24 | Composto glicosídeo, métodos de produção de um tioéter, de éter e de composto glicosídeo, e, éter. |
BR122020014853A BR122020014853B8 (pt) | 2011-08-25 | 2012-08-24 | Éter, e, método de produção de um éter |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR122020014853A BR122020014853B8 (pt) | 2011-08-25 | 2012-08-24 | Éter, e, método de produção de um éter |
Country Status (14)
Country | Link |
---|---|
US (2) | US9481702B2 (pt) |
EP (2) | EP2749565B1 (pt) |
JP (2) | JP5554881B2 (pt) |
KR (1) | KR101761103B1 (pt) |
CN (2) | CN103906758B (pt) |
AU (1) | AU2012297612B9 (pt) |
BR (2) | BR112014004313A8 (pt) |
CA (1) | CA2846572C (pt) |
ES (2) | ES2638147T3 (pt) |
HK (1) | HK1199456A1 (pt) |
IL (2) | IL231089A (pt) |
MX (2) | MX348971B (pt) |
TW (2) | TWI586683B (pt) |
WO (1) | WO2013027843A1 (pt) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6459852B2 (ja) * | 2014-08-29 | 2019-01-30 | 住友化学株式会社 | エーテル化合物の製造方法 |
US10377788B2 (en) | 2015-04-02 | 2019-08-13 | Bonac Corporation | Method for producing glycoside compounds |
CN108473988A (zh) | 2015-12-29 | 2018-08-31 | 国立大学法人北海道大学 | 抑制肾素原基因或肾素原受体基因表达的单链核酸分子及其用途 |
EP3450439B8 (en) | 2016-04-26 | 2021-06-30 | Sumitomo Chemical Company, Limited | Method for producing monomer for single-stranded nucleic acid molecule |
JPWO2018070543A1 (ja) | 2016-10-14 | 2019-07-25 | 株式会社ボナック | 新規な配糖体化合物及びその製造方法 |
EP3604528A4 (en) | 2017-03-31 | 2021-01-13 | Bonac Corporation | CYCLIC NUCLEIC ACID MOLECULE HAVING A GENE EXPRESSION CONTROL FUNCTION |
SG11201913541QA (en) | 2017-07-28 | 2020-02-27 | Kyorin Pharmaceutical Co Ltd | Therapeutic agent for fibrosis |
TWI830718B (zh) | 2018-02-09 | 2024-02-01 | 日商住友化學股份有限公司 | 核酸分子之製造方法 |
CN111819280A (zh) | 2018-03-30 | 2020-10-23 | 东丽株式会社 | 发夹型单链rna分子的制备方法 |
JP6817493B2 (ja) | 2018-03-30 | 2021-01-20 | 住友化学株式会社 | 一本鎖rnaの製造方法 |
JP7280248B2 (ja) * | 2018-04-24 | 2023-05-23 | 住友化学株式会社 | アミダイト化合物及び該化合物を用いたポリヌクレオチドの製造方法 |
US20210355153A1 (en) * | 2018-09-07 | 2021-11-18 | Sumitomo Chemical Company, Limited | Method for producing glycoside compound |
JP7241098B2 (ja) | 2019-01-25 | 2023-03-16 | 杏林製薬株式会社 | 線維症治療剤 |
US20220213134A1 (en) | 2019-03-29 | 2022-07-07 | Sumitomo Chemical Company, Limited | Method for producing rna |
WO2020202951A1 (ja) | 2019-03-29 | 2020-10-08 | 住友化学株式会社 | 無機多孔質担体、及びこれを用いた核酸の製造方法 |
WO2020202950A1 (ja) | 2019-03-29 | 2020-10-08 | 住友化学株式会社 | 無機多孔質担体及びこれを用いた核酸の製造方法 |
US20220177319A1 (en) | 2019-03-29 | 2022-06-09 | Sumitomo Chemical Company, Limited | Inorganic porous support and method for producing nucleic acid using same |
US20220193648A1 (en) | 2019-03-29 | 2022-06-23 | Sumitomo Chemical Company, Limited | Inorganic porous carrier, and production method for nucleic acid using same |
US20230022212A1 (en) * | 2019-10-08 | 2023-01-26 | Sumitomo Chemical Company, Limited | Method for producing glycoside compound |
EP4043473A4 (en) * | 2019-10-11 | 2024-03-27 | Sumitomo Chemical Co | METHOD FOR PRODUCING NUCLEIC ACID OLIGOMERS |
US20230024003A1 (en) | 2019-10-23 | 2023-01-26 | Sumitomo Chemical Company, Limited | Glycoside compound, amidite compound, and production method for polynucleotide using said compounds |
CN115003680A (zh) * | 2020-01-29 | 2022-09-02 | 住友化学株式会社 | 制备核酸寡聚物的方法 |
EP4098655A4 (en) * | 2020-01-29 | 2024-02-28 | Sumitomo Chemical Co | PROCESS FOR THE PRODUCTION OF NUCLEIC ACID OLIGOMERS |
KR20220160010A (ko) | 2020-03-27 | 2022-12-05 | 스미또모 가가꾸 가부시끼가이샤 | 핵산 올리고머의 제조 방법 |
CN115362163A (zh) | 2020-04-14 | 2022-11-18 | 住友化学株式会社 | 核酸寡聚物的制造方法 |
KR20220167282A (ko) | 2020-04-14 | 2022-12-20 | 스미또모 가가꾸 가부시끼가이샤 | 핵산 올리고머를 포함하는 조성물 |
JPWO2021230293A1 (pt) | 2020-05-13 | 2021-11-18 | ||
US20230242570A1 (en) | 2020-07-09 | 2023-08-03 | Sumitomo Chemical Company, Limited | Method for producing nucleic acid oligomer |
EP4206325A1 (en) | 2020-08-25 | 2023-07-05 | Bonac Corporation | Novel nucleic acid molecule inhibiting expression of target gene |
EP4219520A1 (en) | 2020-09-24 | 2023-08-02 | Sumitomo Chemical Company, Limited | Method for producing nucleic acid oligomer |
EP4271695A2 (en) * | 2020-12-31 | 2023-11-08 | Alnylam Pharmaceuticals, Inc. | 2'-modified nucleoside based oligonucleotide prodrugs |
WO2023282120A1 (ja) | 2021-07-06 | 2023-01-12 | 住友化学株式会社 | 核酸オリゴマーを含む組成物 |
JPWO2023054350A1 (pt) | 2021-09-28 | 2023-04-06 | ||
US11897914B2 (en) | 2021-11-29 | 2024-02-13 | Hongene Biotech Corporation | Synthesis of 2′ protected nucleosides |
WO2023182274A1 (ja) * | 2022-03-23 | 2023-09-28 | 住友化学株式会社 | 核酸オリゴマーの製造方法 |
WO2024019137A1 (ja) * | 2022-07-22 | 2024-01-25 | 住友化学株式会社 | オリゴヌクレオチドの製造方法 |
WO2024024766A1 (ja) * | 2022-07-25 | 2024-02-01 | 東レ株式会社 | アルキルハライド、それを用いたアルキル化剤及びヌクレオシド誘導体の製造方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
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NO310238B1 (no) * | 1992-12-24 | 2001-06-11 | Bristol Myers Squibb Co | Kjemiske forbindelser og farmasöytisk preparat samt anvendelse av slike preparater |
CA2129288C (en) | 1993-08-17 | 2000-05-16 | Jerzy Golik | Phosphonooxymethyl esters of taxane derivatives |
US5955600A (en) * | 1996-12-27 | 1999-09-21 | Isis Pharmaceuticals, Inc. | Method for the synthesis of nucleotide or oligonucleotide phosphoramidites |
US6610842B1 (en) * | 1999-05-06 | 2003-08-26 | Isis Pharmaceuticals, Inc. | Processes for the synthesis of oligomers using phosphoramidite compositions |
WO2005085271A1 (ja) * | 2004-03-04 | 2005-09-15 | Japan Science And Technology Agency | 2 ‘水酸基を修飾された新規人工rna |
JP5157168B2 (ja) * | 2004-08-26 | 2013-03-06 | 日本新薬株式会社 | ホスホロアミダイト化合物及びオリゴrnaの製法 |
JP4797156B2 (ja) * | 2005-03-09 | 2011-10-19 | 国立大学法人東京工業大学 | リボヌクレオシドの2’水酸基の脱保護方法 |
JP2008174524A (ja) | 2007-01-22 | 2008-07-31 | Nippon Shinyaku Co Ltd | リボ核酸化合物の製造方法 |
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2012
- 2012-08-24 WO PCT/JP2012/071517 patent/WO2013027843A1/ja active Application Filing
- 2012-08-24 CA CA2846572A patent/CA2846572C/en active Active
- 2012-08-24 MX MX2014002229A patent/MX348971B/es active IP Right Grant
- 2012-08-24 ES ES12825586.6T patent/ES2638147T3/es active Active
- 2012-08-24 CN CN201280052136.6A patent/CN103906758B/zh active Active
- 2012-08-24 ES ES16165401T patent/ES2802996T3/es active Active
- 2012-08-24 JP JP2013527390A patent/JP5554881B2/ja active Active
- 2012-08-24 BR BR112014004313A patent/BR112014004313A8/pt not_active Application Discontinuation
- 2012-08-24 TW TW101130799A patent/TWI586683B/zh active
- 2012-08-24 US US14/240,638 patent/US9481702B2/en active Active
- 2012-08-24 BR BR122020014853A patent/BR122020014853B8/pt active IP Right Grant
- 2012-08-24 EP EP12825586.6A patent/EP2749565B1/en active Active
- 2012-08-24 MX MX2017004740A patent/MX370398B/es unknown
- 2012-08-24 CN CN201710326602.XA patent/CN107253926B/zh active Active
- 2012-08-24 AU AU2012297612A patent/AU2012297612B9/en active Active
- 2012-08-24 TW TW105119719A patent/TWI586684B/zh active
- 2012-08-24 EP EP16165401.7A patent/EP3098230B1/en active Active
- 2012-08-24 KR KR1020147007763A patent/KR101761103B1/ko active IP Right Grant
-
2013
- 2013-10-25 JP JP2013222455A patent/JP5554873B2/ja active Active
-
2014
- 2014-02-23 IL IL231089A patent/IL231089A/en active IP Right Grant
- 2014-12-24 HK HK14112886.6A patent/HK1199456A1/xx unknown
-
2015
- 2015-12-02 IL IL242889A patent/IL242889A/en active IP Right Grant
-
2016
- 2016-03-03 US US15/060,152 patent/US9988415B2/en active Active
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
B25A | Requested transfer of rights approved |
Owner name: SUMITOMO CHEMICAL COMPANY, LIMITED (JP) |