BR112013027153A2 - método de aplicação de fármaco para pth, pthrp e peptídeos relacionados - Google Patents
método de aplicação de fármaco para pth, pthrp e peptídeos relacionadosInfo
- Publication number
- BR112013027153A2 BR112013027153A2 BR112013027153A BR112013027153A BR112013027153A2 BR 112013027153 A2 BR112013027153 A2 BR 112013027153A2 BR 112013027153 A BR112013027153 A BR 112013027153A BR 112013027153 A BR112013027153 A BR 112013027153A BR 112013027153 A2 BR112013027153 A2 BR 112013027153A2
- Authority
- BR
- Brazil
- Prior art keywords
- pthrp
- pth
- related peptides
- drug application
- application method
- Prior art date
Links
- 101150071808 PTHLH gene Proteins 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 4
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Medical Informatics (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Materials For Medical Uses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161478466P | 2011-04-22 | 2011-04-22 | |
| US201161578120P | 2011-12-20 | 2011-12-20 | |
| PCT/US2012/034510 WO2012145665A2 (en) | 2011-04-22 | 2012-04-20 | Method of drug delivery for pth, pthrp and related peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013027153A2 true BR112013027153A2 (pt) | 2016-11-29 |
Family
ID=47042187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013027153A BR112013027153A2 (pt) | 2011-04-22 | 2012-04-20 | método de aplicação de fármaco para pth, pthrp e peptídeos relacionados |
Country Status (14)
| Country | Link |
|---|---|
| US (6) | US20130006217A1 (enExample) |
| EP (2) | EP2699252B1 (enExample) |
| JP (2) | JP6033280B2 (enExample) |
| KR (1) | KR20140047043A (enExample) |
| CN (1) | CN103917242A (enExample) |
| AU (2) | AU2012245301B2 (enExample) |
| BR (1) | BR112013027153A2 (enExample) |
| CA (1) | CA2833571A1 (enExample) |
| ES (1) | ES2648864T3 (enExample) |
| IL (1) | IL228942A0 (enExample) |
| MX (1) | MX2013012349A (enExample) |
| RU (1) | RU2013151314A (enExample) |
| SG (1) | SG194570A1 (enExample) |
| WO (1) | WO2012145665A2 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012018486A2 (en) * | 2010-07-26 | 2012-02-09 | Seventh Sense Biosystems, Inc. | Rapid delivery and/or receiving of fluids |
| ME02474B (me) | 2010-05-12 | 2017-02-20 | Radius Health Inc | Terapijski režimi |
| EP2621901B1 (en) | 2010-09-28 | 2015-07-29 | Radius Health, Inc | Selective androgen receptor modulators |
| EP2992827B1 (en) | 2010-11-09 | 2017-04-19 | Seventh Sense Biosystems, Inc. | Systems and interfaces for blood sampling |
| BR112014013099A8 (pt) * | 2011-11-30 | 2023-05-09 | 3M Innovative Properties Company | Dispositivo de microagulhas incluindo um agente terapêutico peptídeo e um aminoácido e métodos para produzir e usar o dispositivo |
| HK1209657A1 (en) * | 2012-08-30 | 2016-04-08 | Teijin Limited | Microneedle array coated with drug composition |
| SMT202300072T1 (it) | 2014-03-28 | 2023-05-12 | Univ Duke | Cancro della mammella mediante l'utilizzo di modulatori selettivi del recetiore degli estrogeni |
| EP3265115B1 (en) * | 2015-03-03 | 2022-06-22 | Radius Health, Inc. | Abaloparatide combined with alendronate for reducing non-vertebral bone fractures |
| MX393599B (es) | 2015-04-29 | 2025-03-19 | Radius Pharmaceuticals Inc | Rad1901 para usarse en el tratamiento de cancer en sujetos con cancer positivo a receptor de estrogeno alfa resistente a farmaco |
| US20180161401A1 (en) * | 2015-07-06 | 2018-06-14 | Zheng Xin Dong | Novel Formulations of PTHrP Analogue |
| SMT202100411T1 (it) * | 2015-10-09 | 2021-11-12 | Radius Health Inc | Formulazioni di analoghi di pthrp, loro cerotti transdermici, e loro usi |
| JP7116680B2 (ja) | 2015-10-09 | 2022-08-10 | キンデーバ ドラッグ デリバリー リミティド パートナーシップ | コーティングされたマイクロニードルアレイのための亜鉛組成物 |
| JP6920341B2 (ja) * | 2016-04-18 | 2021-08-18 | ラジウス ヘルス，インコーポレイテッド | アバロパラチドの製剤、その経皮パッチ、およびその使用 |
| RU2022108295A (ru) | 2016-06-22 | 2022-04-06 | Эллипсес Фарма Лтд | Способы лечения ar+ рака молочной железы |
| WO2018102616A1 (en) * | 2016-11-30 | 2018-06-07 | Purdue Research Foundation | Fracture targeted bone regeneration through parathyroid hormone receptor stimulation |
| CN117417263A (zh) | 2017-01-05 | 2024-01-19 | 雷迪厄斯制药公司 | Rad1901-2hcl的多晶型形式 |
| US9968767B1 (en) | 2017-10-10 | 2018-05-15 | King Saud University | Combination microarray patch for drug delivery and electrochemotherapy device |
| WO2019232280A1 (en) | 2018-05-30 | 2019-12-05 | Purdue Research Foundation | Targeting anabolic drugs for accelerated fracture repair |
| CN112423844B (zh) | 2018-07-04 | 2024-08-13 | 雷迪厄斯制药公司 | Rad1901-2hcl的多晶型形式 |
| MA54946A (fr) | 2019-02-12 | 2021-12-22 | Radius Pharmaceuticals Inc | Procédés et composés |
| EP4110371A1 (en) | 2020-01-24 | 2023-01-04 | Radius Health, Inc. | Methods of stimulating bone growth with abalopartide and denosumab |
| BR112022022039A2 (pt) | 2020-04-28 | 2022-12-13 | Ticona Llc | Conjunto de microagulhas |
| EP4142693A1 (en) * | 2020-05-01 | 2023-03-08 | Emergex USA Corporation | Transdermal drug delivery devices having psilocybin, lysergic acid diethylamide or 3,4-methylenedioxymethamphetamine coated microprotrusions |
| AU2022205801A1 (en) * | 2021-01-05 | 2023-07-13 | Radius Health, Inc. | Treatment of long bone fractures with abaloparatide |
| US12048543B2 (en) | 2021-11-08 | 2024-07-30 | Satio, Inc. | Dermal patch for collecting a physiological sample with removable vial |
| US12053284B2 (en) | 2021-11-08 | 2024-08-06 | Satio, Inc. | Dermal patch for collecting a physiological sample |
| US12214346B2 (en) | 2021-10-13 | 2025-02-04 | Satio, Inc. | Dermal patch with a diagnostic test strip |
| US11452474B1 (en) | 2021-04-14 | 2022-09-27 | Satio, Inc. | Dual lever dermal patch system |
| US11877848B2 (en) | 2021-11-08 | 2024-01-23 | Satio, Inc. | Dermal patch for collecting a physiological sample |
| US12023156B2 (en) | 2021-10-13 | 2024-07-02 | Satio, Inc. | Dermal patch for collecting a physiological sample |
| US11964121B2 (en) | 2021-10-13 | 2024-04-23 | Satio, Inc. | Mono dose dermal patch for pharmaceutical delivery |
| US12178979B2 (en) | 2021-10-13 | 2024-12-31 | Satio, Inc. | Dermal patch for delivering a pharmaceutical |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6544949B1 (en) * | 1995-07-13 | 2003-04-08 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Analogs of parathyroid hormone |
| US5969095A (en) | 1995-07-13 | 1999-10-19 | Biomeasure, Inc. | Analogs of parathyroid hormone |
| CN1161164C (zh) * | 1997-12-11 | 2004-08-11 | 阿尔扎有限公司 | 用于通过体表导入或提取质剂的装置 |
| JP2001525232A (ja) * | 1997-12-11 | 2001-12-11 | アルザ・コーポレーション | 経皮物質の流れを増強するための装置 |
| US6091975A (en) * | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
| GB9930882D0 (en) * | 1999-12-30 | 2000-02-23 | Nps Allelix Corp | GLP-2 formulations |
| US20050106227A1 (en) * | 2003-10-28 | 2005-05-19 | Samuel Zalipsky | Delivery of polymer conjugates of therapeutic peptides and proteins via coated microprojections |
| EP1680154B1 (en) * | 2003-10-31 | 2012-01-04 | ALZA Corporation | Self-actuating applicator for microprojection array |
| MXPA06005510A (es) * | 2003-11-13 | 2006-12-14 | Johnson & Johnson | Composicion y aparato para distribucion transdermica. |
| EP1744683B1 (en) | 2004-05-13 | 2016-03-16 | Alza Corporation | Apparatus and method for transdermal delivery of parathyroid hormone agents |
| US8057842B2 (en) | 2004-11-18 | 2011-11-15 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
| JP2009522288A (ja) * | 2005-12-28 | 2009-06-11 | アルザ コーポレイション | 安定な治療剤形 |
| CA2680690A1 (en) * | 2006-03-15 | 2007-09-20 | Alza Corporation | Apparatus and method for transdermal delivery of parathyroid hormone agents to prevent or treat osteopenia |
| CN101472676B (zh) * | 2006-04-20 | 2013-09-11 | 万罗赛斯公司 | 利用微通道工艺技术处理和/或形成一种非牛顿流体的方法 |
| US9119945B2 (en) | 2006-04-20 | 2015-09-01 | 3M Innovative Properties Company | Device for applying a microneedle array |
| DK2957278T3 (en) | 2006-10-03 | 2017-07-31 | Radius Health Inc | STABLE COMPOSITION COMPREHENSIVE PTHRP AND APPLICATIONS THEREOF |
| US7803770B2 (en) | 2006-10-03 | 2010-09-28 | Radius Health, Inc. | Method of treating osteoporosis comprising administration of PTHrP analog |
| EP2119469B1 (en) * | 2007-02-06 | 2014-05-14 | Hisamitsu Pharmaceutical Co., Inc. | Microneedle device for diagnosis of allergy |
| JP5559054B2 (ja) * | 2007-09-28 | 2014-07-23 | ザ クイーンズ ユニヴァーシティ オブ ベルファスト | 送達装置および方法 |
| WO2009054988A1 (en) * | 2007-10-23 | 2009-04-30 | Alza Corporation | Transdermal sustained release drug delivery |
| EP2052736A1 (en) * | 2007-10-26 | 2009-04-29 | Nycomed Danmark ApS | Parathyroid hormone formulations und uses thereof |
| MX2011004453A (es) | 2008-11-04 | 2011-08-12 | Aska Pharm Co Ltd | Composicion acuosa que contiene hormona foliculo estimulante. |
| US20110172609A1 (en) * | 2010-01-08 | 2011-07-14 | Ratio, Inc. | Microneedle component assembly for drug delivery device |
-
2012
- 2012-04-20 US US13/452,412 patent/US20130006217A1/en not_active Abandoned
- 2012-04-20 RU RU2013151314/15A patent/RU2013151314A/ru unknown
- 2012-04-20 WO PCT/US2012/034510 patent/WO2012145665A2/en not_active Ceased
- 2012-04-20 CA CA2833571A patent/CA2833571A1/en not_active Abandoned
- 2012-04-20 BR BR112013027153A patent/BR112013027153A2/pt not_active IP Right Cessation
- 2012-04-20 AU AU2012245301A patent/AU2012245301B2/en not_active Ceased
- 2012-04-20 EP EP12773751.8A patent/EP2699252B1/en active Active
- 2012-04-20 EP EP17190659.7A patent/EP3332799A1/en not_active Withdrawn
- 2012-04-20 ES ES12773751.8T patent/ES2648864T3/es active Active
- 2012-04-20 MX MX2013012349A patent/MX2013012349A/es not_active Application Discontinuation
- 2012-04-20 KR KR1020137031111A patent/KR20140047043A/ko not_active Withdrawn
- 2012-04-20 JP JP2014506585A patent/JP6033280B2/ja not_active Expired - Fee Related
- 2012-04-20 CN CN201280030749.XA patent/CN103917242A/zh active Pending
- 2012-04-20 SG SG2013078324A patent/SG194570A1/en unknown
-
2013
- 2013-03-08 US US13/791,360 patent/US20140046293A1/en not_active Abandoned
- 2013-03-08 US US13/791,170 patent/US20140046292A1/en not_active Abandoned
- 2013-10-17 IL IL228942A patent/IL228942A0/en unknown
-
2016
- 2016-08-16 AU AU2016216584A patent/AU2016216584A1/en not_active Abandoned
- 2016-10-25 JP JP2016208896A patent/JP2017036323A/ja active Pending
- 2016-11-14 US US15/351,317 patent/US20170189493A1/en not_active Abandoned
-
2019
- 2019-02-19 US US16/279,770 patent/US20190290738A1/en not_active Abandoned
-
2020
- 2020-08-31 US US17/008,603 patent/US20210052705A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2699252A4 (en) | 2015-05-27 |
| KR20140047043A (ko) | 2014-04-21 |
| CA2833571A1 (en) | 2012-10-26 |
| RU2013151314A (ru) | 2015-05-27 |
| EP2699252B1 (en) | 2017-10-25 |
| ES2648864T3 (es) | 2018-01-08 |
| MX2013012349A (es) | 2014-07-09 |
| US20190290738A1 (en) | 2019-09-26 |
| EP2699252A2 (en) | 2014-02-26 |
| US20170189493A1 (en) | 2017-07-06 |
| AU2016216584A1 (en) | 2016-09-01 |
| US20140046293A1 (en) | 2014-02-13 |
| JP6033280B2 (ja) | 2016-11-30 |
| EP3332799A1 (en) | 2018-06-13 |
| NZ618003A (en) | 2016-05-27 |
| JP2017036323A (ja) | 2017-02-16 |
| US20210052705A1 (en) | 2021-02-25 |
| US20130006217A1 (en) | 2013-01-03 |
| SG194570A1 (en) | 2013-12-30 |
| CN103917242A (zh) | 2014-07-09 |
| WO2012145665A3 (en) | 2014-04-24 |
| JP2014517825A (ja) | 2014-07-24 |
| IL228942A0 (en) | 2013-12-31 |
| US20140046292A1 (en) | 2014-02-13 |
| WO2012145665A2 (en) | 2012-10-26 |
| AU2012245301B2 (en) | 2016-05-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO ARQUIVAMENTO PUBLICADO NA RPI 2510 DE 12/02/2019. |