JP6033280B2 - ＰＴＨ、ＰＴＨｒＰ、および関連ペプチドの薬剤送達方法 - Google Patents

ＰＴＨ、ＰＴＨｒＰ、および関連ペプチドの薬剤送達方法 Download PDF

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Publication number
JP6033280B2
JP6033280B2 JP2014506585A JP2014506585A JP6033280B2 JP 6033280 B2 JP6033280 B2 JP 6033280B2 JP 2014506585 A JP2014506585 A JP 2014506585A JP 2014506585 A JP2014506585 A JP 2014506585A JP 6033280 B2 JP6033280 B2 JP 6033280B2
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leu
glu
lys
aib
hpthrp
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JP2014517825A5 (enExample
JP2014517825A (ja
Inventor
ハタスリー，ガリー
ハンセン，クリス，ジェイ．
デターマン，アミー，エス．
チャン，イン
Original Assignee
ラジウス ヘルス，インコーポレイテッド
ラジウス ヘルス，インコーポレイテッド
スリーエム イノベイティブ プロパティーズ カンパニー，ア フォーリー オウンド サブシディアリー オブ スリーエム カンパニー
スリーエム イノベイティブ プロパティーズ カンパニー，ア フォーリー オウンド サブシディアリー オブ スリーエム カンパニー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Medical Informatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
JP2014506585A 2011-04-22 2012-04-20 ＰＴＨ、ＰＴＨｒＰ、および関連ペプチドの薬剤送達方法 Expired - Fee Related JP6033280B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161478466P 2011-04-22 2011-04-22
US61/478,466 2011-04-22
US201161578120P 2011-12-20 2011-12-20
US61/578,120 2011-12-20
PCT/US2012/034510 WO2012145665A2 (en) 2011-04-22 2012-04-20 Method of drug delivery for pth, pthrp and related peptides

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016208896A Division JP2017036323A (ja) 2011-04-22 2016-10-25 ＰＴＨ、ＰＴＨｒＰ、および関連ペプチドの薬剤送達方法

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Publication Number Publication Date
JP2014517825A JP2014517825A (ja) 2014-07-24
JP2014517825A5 JP2014517825A5 (enExample) 2015-06-11
JP6033280B2 true JP6033280B2 (ja) 2016-11-30

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JP2014506585A Expired - Fee Related JP6033280B2 (ja) 2011-04-22 2012-04-20 ＰＴＨ、ＰＴＨｒＰ、および関連ペプチドの薬剤送達方法
JP2016208896A Pending JP2017036323A (ja) 2011-04-22 2016-10-25 ＰＴＨ、ＰＴＨｒＰ、および関連ペプチドの薬剤送達方法

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Country Link
US (6) US20130006217A1 (enExample)
EP (2) EP2699252B1 (enExample)
JP (2) JP6033280B2 (enExample)
KR (1) KR20140047043A (enExample)
CN (1) CN103917242A (enExample)
AU (2) AU2012245301B2 (enExample)
BR (1) BR112013027153A2 (enExample)
CA (1) CA2833571A1 (enExample)
ES (1) ES2648864T3 (enExample)
IL (1) IL228942A0 (enExample)
MX (1) MX2013012349A (enExample)
RU (1) RU2013151314A (enExample)
SG (1) SG194570A1 (enExample)
WO (1) WO2012145665A2 (enExample)

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Also Published As

Publication number Publication date
NZ618003A (en) 2016-05-27
CA2833571A1 (en) 2012-10-26
EP2699252B1 (en) 2017-10-25
AU2012245301B2 (en) 2016-05-19
RU2013151314A (ru) 2015-05-27
WO2012145665A2 (en) 2012-10-26
SG194570A1 (en) 2013-12-30
ES2648864T3 (es) 2018-01-08
JP2017036323A (ja) 2017-02-16
JP2014517825A (ja) 2014-07-24
AU2016216584A1 (en) 2016-09-01
EP3332799A1 (en) 2018-06-13
US20130006217A1 (en) 2013-01-03
BR112013027153A2 (pt) 2016-11-29
EP2699252A2 (en) 2014-02-26
WO2012145665A3 (en) 2014-04-24
EP2699252A4 (en) 2015-05-27
US20190290738A1 (en) 2019-09-26
US20210052705A1 (en) 2021-02-25
IL228942A0 (en) 2013-12-31
US20140046292A1 (en) 2014-02-13
CN103917242A (zh) 2014-07-09
MX2013012349A (es) 2014-07-09
US20170189493A1 (en) 2017-07-06
KR20140047043A (ko) 2014-04-21
US20140046293A1 (en) 2014-02-13

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