SG11201402661TA - Therapeutic agents comprising insulin amino acid sequences - Google Patents

Therapeutic agents comprising insulin amino acid sequences

Info

Publication number
SG11201402661TA
SG11201402661TA SG11201402661TA SG11201402661TA SG11201402661TA SG 11201402661T A SG11201402661T A SG 11201402661TA SG 11201402661T A SG11201402661T A SG 11201402661TA SG 11201402661T A SG11201402661T A SG 11201402661TA SG 11201402661T A SG11201402661T A SG 11201402661TA
Authority
SG
Singapore
Prior art keywords
amino acid
acid sequences
therapeutic agents
insulin amino
insulin
Prior art date
Application number
SG11201402661TA
Inventor
James Jowett
Christopher Woods
Original Assignee
Phasebio Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phasebio Pharmaceuticals Inc filed Critical Phasebio Pharmaceuticals Inc
Publication of SG11201402661TA publication Critical patent/SG11201402661TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
SG11201402661TA 2011-11-28 2012-11-28 Therapeutic agents comprising insulin amino acid sequences SG11201402661TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161563985P 2011-11-28 2011-11-28
PCT/US2012/066795 WO2013082116A1 (en) 2011-11-28 2012-11-28 Therapeutic agents comprising insulin amino acid sequences

Publications (1)

Publication Number Publication Date
SG11201402661TA true SG11201402661TA (en) 2014-08-28

Family

ID=48536000

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201402661TA SG11201402661TA (en) 2011-11-28 2012-11-28 Therapeutic agents comprising insulin amino acid sequences

Country Status (14)

Country Link
US (2) US20130150291A1 (en)
EP (1) EP2785367A4 (en)
JP (1) JP2014534265A (en)
KR (1) KR20140103985A (en)
CN (1) CN104080473A (en)
AU (1) AU2012346058A1 (en)
BR (1) BR112014012789A2 (en)
CA (1) CA2856967A1 (en)
HK (1) HK1202067A1 (en)
IL (1) IL232781A0 (en)
MX (1) MX2014006391A (en)
RU (1) RU2014126244A (en)
SG (1) SG11201402661TA (en)
WO (1) WO2013082116A1 (en)

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US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US8841255B2 (en) 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
CA2953975C (en) 2008-06-27 2019-11-26 Duke University Therapeutic agents comprising elastin-like peptides
US9561262B2 (en) 2011-06-06 2017-02-07 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
US20150290328A1 (en) 2012-11-20 2015-10-15 Phasebio Pharmaceuticals, Inc. Formulations of active agents for sustained release
JP2016505627A (en) * 2013-01-15 2016-02-25 フェーズバイオ ファーマシューティカルズ,インコーポレイテッド Therapeutic agents, compositions, and methods for glycemic control
CA2947982C (en) 2014-05-08 2022-11-29 Phasebio Pharmaceuticals, Inc. Methods and compositions for treating cystic fibrosis
EP3220936A4 (en) * 2014-11-21 2018-08-22 Phasebio Pharmaceuticals, Inc. Elp fusion proteins for controlled and sustained release
AU2016219513B2 (en) 2015-02-09 2021-09-30 Immunoforge Co., Ltd. Methods and compositions for treating muscle disease and disorders
TW201718627A (en) * 2015-06-11 2017-06-01 梅茲製藥有限兩合公司 Recombinant clostridial neurotoxin, a use thereof, and a method for generating the same, a pharmaceutical composition comprising the same and a precursor corresponding to the same, a nucleic acid sequence encoding the precursor and a method for obtaining
EP3124495A1 (en) * 2015-07-31 2017-02-01 Centre National de la Recherche Scientifique (C.N.R.S.) Derivatives of elastin-like polypeptides and uses thereof
JP6882782B2 (en) 2015-08-04 2021-06-02 デューク ユニバーシティ Genetically encoded, essentially chaotic delivery stealth polymers and how to use them
CN105061566A (en) * 2015-09-05 2015-11-18 苏州普罗达生物科技有限公司 Pseudoinsulin polypeptide and application thereof
CN108473548A (en) * 2015-09-24 2018-08-31 韩美药品股份有限公司 Insulin production method
KR101815080B1 (en) * 2015-11-03 2018-01-04 재단법인대구경북과학기술원 Pharmaceutical composition for treating diabetes comprising islet and artificial extracellular matrix of elastin like polypeptide
US11752213B2 (en) 2015-12-21 2023-09-12 Duke University Surfaces having reduced non-specific binding and antigenicity
EP3448872A4 (en) 2016-04-27 2019-12-11 The Regents of the University of California Preparation of functional homocysteine residues in polypeptides and peptides
MX2018013546A (en) * 2016-05-06 2019-04-22 Phasebio Pharmaceuticals Inc Elp fusion proteins for controlled and sustained release.
US11467156B2 (en) 2016-06-01 2022-10-11 Duke University Nonfouling biosensors
KR20190064600A (en) 2016-09-23 2019-06-10 듀크 유니버시티 Unstructured non-repetitive polypeptides with LCST behavior
US11220467B2 (en) 2017-01-11 2022-01-11 Recycle Track Systems, Inc. Indoor food waste fermentation and recycling process
US11648200B2 (en) 2017-01-12 2023-05-16 Duke University Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly
WO2018213320A1 (en) 2017-05-15 2018-11-22 Duke University Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents
WO2018233813A1 (en) 2017-06-20 2018-12-27 Merz Pharma Gmbh & Co. Kgaa Novel recombinant botulinum toxin with increased duration of effect
WO2019006374A1 (en) 2017-06-30 2019-01-03 Duke University Order and disorder as a design principle for stimuli-responsive biopolymer networks
US11155802B2 (en) 2017-07-06 2021-10-26 Merz Pharma Gmbh & Co. Kgaa Recombinant botulinum neurotoxins with increased duration of effect
EP3829622A4 (en) 2018-08-02 2022-05-11 Duke University Dual agonist fusion proteins
CN111939244A (en) * 2019-05-14 2020-11-17 阿莫生命科学有限公司 Pharmaceutical composition for preventing or treating diabetic complications
KR102456958B1 (en) * 2019-05-14 2022-10-21 강원대학교 산학협력단 Pharmaceutical composition for treating or preventing diabetic complications
US11512314B2 (en) 2019-07-12 2022-11-29 Duke University Amphiphilic polynucleotides
JPWO2021112249A1 (en) * 2019-12-06 2021-06-10

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
CN1278737A (en) * 1997-11-12 2001-01-03 阿尔萨公司 Method for decreasing self-association of polypeptides
US7846445B2 (en) * 2005-09-27 2010-12-07 Amunix Operating, Inc. Methods for production of unstructured recombinant polymers and uses thereof
WO2007073486A2 (en) * 2005-12-20 2007-06-28 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
MX2008010562A (en) * 2006-02-15 2009-03-05 Imclone Systems Inc Antibody formulation.
CN101438158A (en) * 2006-03-06 2009-05-20 阿穆尼克斯股份有限公司 Genetic packages and uses thereof
CA2953975C (en) * 2008-06-27 2019-11-26 Duke University Therapeutic agents comprising elastin-like peptides
WO2010014689A1 (en) * 2008-07-29 2010-02-04 Phasebio Pharmaceuticals, Inc. Pharmaceutical formulations comprising elastin-like proteins
SG178195A1 (en) * 2009-07-31 2012-03-29 Sanofi Aventis Deutschland Long acting insulin composition
KR101943420B1 (en) * 2009-08-14 2019-04-17 파세비오 파마수티컬스 인코포레이티드 Modified Vasoactive Intestinal Peptide

Also Published As

Publication number Publication date
US20140364362A1 (en) 2014-12-11
JP2014534265A (en) 2014-12-18
CA2856967A1 (en) 2013-06-06
RU2014126244A (en) 2016-01-27
US20130150291A1 (en) 2013-06-13
KR20140103985A (en) 2014-08-27
WO2013082116A1 (en) 2013-06-06
AU2012346058A1 (en) 2014-06-12
EP2785367A4 (en) 2015-06-17
IL232781A0 (en) 2014-07-31
EP2785367A1 (en) 2014-10-08
MX2014006391A (en) 2014-09-22
HK1202067A1 (en) 2015-09-18
BR112014012789A2 (en) 2019-09-24
CN104080473A (en) 2014-10-01

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