BR112012009481A2 - método e dispositivo para detectar uma pluralidade de alvos em uma amostra biológica, e, kit para detectar uma pluralidade de alvos múltiplos em uma amostra biológica - Google Patents

método e dispositivo para detectar uma pluralidade de alvos em uma amostra biológica, e, kit para detectar uma pluralidade de alvos múltiplos em uma amostra biológica

Info

Publication number
BR112012009481A2
BR112012009481A2 BR112012009481A BR112012009481A BR112012009481A2 BR 112012009481 A2 BR112012009481 A2 BR 112012009481A2 BR 112012009481 A BR112012009481 A BR 112012009481A BR 112012009481 A BR112012009481 A BR 112012009481A BR 112012009481 A2 BR112012009481 A2 BR 112012009481A2
Authority
BR
Brazil
Prior art keywords
biological sample
detecting
targets
kit
target
Prior art date
Application number
BR112012009481A
Other languages
English (en)
Inventor
Anup Sood
John Richard Nelson
Michael Gerdes
Original Assignee
Gen Electric
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Electric filed Critical Gen Electric
Publication of BR112012009481A2 publication Critical patent/BR112012009481A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

método e dispositivo para detectar uma pluralidade de alvos em uma amostra biológica, e, kit para detectar uma pluralidade de alvos múltiplos em uma amostra biológica. métodos para detectar uma pluralidade de alvos em uma amostra biológica são fornecidos. o método compreende contatar a amostra biológica com uma pluralidade de sondas de ligação-alvo para formar uma pluralidade de sondas ligadas ao alvo, ligar covalentemente pelo menos uma das sondas ligadas ao alvo á amostra biológica e observando-se os sinais das sondas ligadas ao alvo sequencialmente. um kit e dispositivo associados para a detecção da pluralidade de alvos também são conhecidos.
BR112012009481A 2009-10-21 2010-10-21 método e dispositivo para detectar uma pluralidade de alvos em uma amostra biológica, e, kit para detectar uma pluralidade de alvos múltiplos em uma amostra biológica BR112012009481A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/582,745 US9677125B2 (en) 2009-10-21 2009-10-21 Detection of plurality of targets in biological samples
PCT/EP2010/065876 WO2011048184A1 (en) 2009-10-21 2010-10-21 Detection of plurality of targets in biological samples

Publications (1)

Publication Number Publication Date
BR112012009481A2 true BR112012009481A2 (pt) 2016-11-29

Family

ID=43103438

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012009481A BR112012009481A2 (pt) 2009-10-21 2010-10-21 método e dispositivo para detectar uma pluralidade de alvos em uma amostra biológica, e, kit para detectar uma pluralidade de alvos múltiplos em uma amostra biológica

Country Status (11)

Country Link
US (1) US9677125B2 (pt)
EP (1) EP2491132B1 (pt)
JP (1) JP2013507941A (pt)
KR (1) KR20120088716A (pt)
CN (1) CN102803510A (pt)
AU (1) AU2010309739A1 (pt)
BR (1) BR112012009481A2 (pt)
CA (1) CA2777421A1 (pt)
IN (1) IN2012DN03156A (pt)
RU (1) RU2012115681A (pt)
WO (1) WO2011048184A1 (pt)

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Also Published As

Publication number Publication date
EP2491132B1 (en) 2018-03-21
CN102803510A (zh) 2012-11-28
US9677125B2 (en) 2017-06-13
WO2011048184A1 (en) 2011-04-28
KR20120088716A (ko) 2012-08-08
EP2491132A1 (en) 2012-08-29
US20110092381A1 (en) 2011-04-21
RU2012115681A (ru) 2013-11-27
IN2012DN03156A (pt) 2015-09-18
CA2777421A1 (en) 2011-04-28
JP2013507941A (ja) 2013-03-07
AU2010309739A1 (en) 2012-05-03

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