BR112012005888A2 - membrana do grafeno de camada única desencapada tendo um nanoporo com habilitação para detecção e análise molecular de alta sensibilidade - Google Patents

membrana do grafeno de camada única desencapada tendo um nanoporo com habilitação para detecção e análise molecular de alta sensibilidade

Info

Publication number
BR112012005888A2
BR112012005888A2 BR112012005888A BR112012005888A BR112012005888A2 BR 112012005888 A2 BR112012005888 A2 BR 112012005888A2 BR 112012005888 A BR112012005888 A BR 112012005888A BR 112012005888 A BR112012005888 A BR 112012005888A BR 112012005888 A2 BR112012005888 A2 BR 112012005888A2
Authority
BR
Brazil
Prior art keywords
nanopore
high sensitivity
layer graphene
molecular detection
graphene membrane
Prior art date
Application number
BR112012005888A
Other languages
English (en)
Other versions
BR112012005888B1 (pt
Inventor
Branton Daniel
Slaven Garaj
A Golovchenko Jene
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of BR112012005888A2 publication Critical patent/BR112012005888A2/pt
Publication of BR112012005888B1 publication Critical patent/BR112012005888B1/pt

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/12—Coulter-counters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
    • C12Q2565/631—Detection means characterised by use of a special device being a biochannel or pore
    • G01N15/1023—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N2015/0038—Investigating nanoparticles
BR112012005888A 2009-09-18 2010-09-17 sensores de nanoporo de grafeno e método para avaliar uma molécula de polímero BR112012005888B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24360709P 2009-09-18 2009-09-18
US35552810P 2010-06-16 2010-06-16
PCT/US2010/049238 WO2011046706A1 (en) 2009-09-18 2010-09-17 Bare single-layer graphene membrane having a nanopore enabling high-sensitivity molecular detection and analysis

Publications (2)

Publication Number Publication Date
BR112012005888A2 true BR112012005888A2 (pt) 2017-06-06
BR112012005888B1 BR112012005888B1 (pt) 2019-10-22

Family

ID=43057332

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012005888A BR112012005888B1 (pt) 2009-09-18 2010-09-17 sensores de nanoporo de grafeno e método para avaliar uma molécula de polímero

Country Status (9)

Country Link
US (2) US10564144B2 (pt)
EP (2) EP3196645B1 (pt)
JP (2) JP5612695B2 (pt)
KR (1) KR101732207B1 (pt)
CN (1) CN102630304B (pt)
AU (3) AU2010307229B2 (pt)
BR (1) BR112012005888B1 (pt)
CA (1) CA2772789C (pt)
WO (1) WO2011046706A1 (pt)

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Also Published As

Publication number Publication date
AU2016203366A1 (en) 2016-06-16
US10564144B2 (en) 2020-02-18
EP3196645B1 (en) 2019-06-19
EP2470899A1 (en) 2012-07-04
KR101732207B1 (ko) 2017-05-02
JP2015014613A (ja) 2015-01-22
AU2018201010A1 (en) 2018-03-01
CN102630304A (zh) 2012-08-08
EP3196645A1 (en) 2017-07-26
US20120234679A1 (en) 2012-09-20
KR20120069720A (ko) 2012-06-28
CN102630304B (zh) 2014-11-26
WO2011046706A1 (en) 2011-04-21
BR112012005888B1 (pt) 2019-10-22
JP2013505448A (ja) 2013-02-14
JP6054922B2 (ja) 2016-12-27
CA2772789C (en) 2018-10-30
EP2470899B1 (en) 2017-03-15
US20200158712A1 (en) 2020-05-21
AU2018201010B2 (en) 2020-03-12
CA2772789A1 (en) 2011-04-21
AU2010307229A1 (en) 2012-04-12
JP5612695B2 (ja) 2014-10-22
AU2010307229B2 (en) 2016-02-25

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