BR0213805A - Células estromais derivadas de tecido adiposo para diferenciação endócrina do pâncreas e usos das mesmas - Google Patents
Células estromais derivadas de tecido adiposo para diferenciação endócrina do pâncreas e usos das mesmasInfo
- Publication number
- BR0213805A BR0213805A BR0213805-0A BR0213805A BR0213805A BR 0213805 A BR0213805 A BR 0213805A BR 0213805 A BR0213805 A BR 0213805A BR 0213805 A BR0213805 A BR 0213805A
- Authority
- BR
- Brazil
- Prior art keywords
- derived stromal
- stromal cells
- pancreas
- cells
- fat
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/39—Pancreas; Islets of Langerhans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/126—Immunoprotecting barriers, e.g. jackets, diffusion chambers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1305—Adipocytes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1384—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from adipose-derived stem cells [ADSC], from adipose stromal stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Nutrition Science (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Physiology (AREA)
- Developmental Biology & Embryology (AREA)
- Dentistry (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Environmental Sciences (AREA)
Abstract
"CéLULAS ESTROMAIS DERIVADAS DE TECIDO ADIPOSO PARA DIFERENCIAçãO ENDóCRINA DO PâNCREAS E USOS DAS MESMAS". A invenção fornece células, composições e métodos baseados na diferenciação de células estromais derivadas de tecido adiposo em uma, célula que expressa pelo menos uma característica genotípica ou fenotípica de uma célula pancreática. As células produzidas no método são úteis no fornecimento de uma fonte de células diferenciadas e funcionais para pesquisa, implantação, transplante e desenvolvimento de produtos de engenharia de tecido para o tratamento de doenças do pâncreas e reparo de tecido pancreático.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34491301P | 2001-11-09 | 2001-11-09 | |
PCT/US2002/036373 WO2003039489A2 (en) | 2001-11-09 | 2002-11-12 | Endocrine pancreas differentiation of adipose tissue-derived stromal cells and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0213805A true BR0213805A (pt) | 2005-08-16 |
Family
ID=23352635
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0213805-0A BR0213805A (pt) | 2001-11-09 | 2002-11-12 | Células estromais derivadas de tecido adiposo para diferenciação endócrina do pâncreas e usos das mesmas |
Country Status (14)
Country | Link |
---|---|
US (1) | US20030124721A1 (pt) |
EP (1) | EP1453954A4 (pt) |
JP (2) | JP2005533480A (pt) |
KR (2) | KR20050044393A (pt) |
CN (1) | CN1596305A (pt) |
AU (1) | AU2002359390A1 (pt) |
BR (1) | BR0213805A (pt) |
CA (1) | CA2465950A1 (pt) |
CZ (1) | CZ2004696A3 (pt) |
HU (1) | HUP0500699A3 (pt) |
MX (1) | MXPA04004311A (pt) |
PL (1) | PL374557A1 (pt) |
RU (1) | RU2351648C2 (pt) |
WO (1) | WO2003039489A2 (pt) |
Families Citing this family (64)
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US8491883B2 (en) * | 2003-06-27 | 2013-07-23 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
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ES2300320T3 (es) * | 2000-02-26 | 2008-06-16 | Artecel, Inc. | Celulas madre pluripotentes generadas a partir de celulas del estroma derivadas de tejido adiposo y sus usos. |
ES2299417T3 (es) * | 2000-04-12 | 2008-06-01 | Beta-Cell N.V. | Metodo para producir preparaciones de celulas endocrinas pancreaticas madura e inmaduras, preparacion de las celulas y su utilizacion para el tratamiento de la diabetes mellitus. |
US20020136709A1 (en) * | 2000-12-12 | 2002-09-26 | Nucleus Remodeling, Inc. | In vitro-derived adult pluripotent stem cells and uses therefor |
US20040121460A1 (en) * | 2001-01-24 | 2004-06-24 | Lumelsky Nadya L | Differentiation of stem cells to pancreatic endocrine cells |
JP2005506074A (ja) * | 2001-10-18 | 2005-03-03 | イクシオン・バイオテクノロジー・インコーポレーテッド | 肝臓の幹細胞および前駆細胞の膵臓機能細胞への転換 |
-
2002
- 2002-11-12 AU AU2002359390A patent/AU2002359390A1/en not_active Abandoned
- 2002-11-12 RU RU2004117530/13A patent/RU2351648C2/ru not_active IP Right Cessation
- 2002-11-12 KR KR1020047007085A patent/KR20050044393A/ko not_active Application Discontinuation
- 2002-11-12 KR KR1020097022668A patent/KR20090115984A/ko not_active Application Discontinuation
- 2002-11-12 CA CA002465950A patent/CA2465950A1/en not_active Abandoned
- 2002-11-12 JP JP2003541781A patent/JP2005533480A/ja not_active Withdrawn
- 2002-11-12 WO PCT/US2002/036373 patent/WO2003039489A2/en active Application Filing
- 2002-11-12 BR BR0213805-0A patent/BR0213805A/pt not_active Application Discontinuation
- 2002-11-12 MX MXPA04004311A patent/MXPA04004311A/es not_active Application Discontinuation
- 2002-11-12 HU HU0500699A patent/HUP0500699A3/hu unknown
- 2002-11-12 PL PL02374557A patent/PL374557A1/xx not_active Application Discontinuation
- 2002-11-12 US US10/293,398 patent/US20030124721A1/en not_active Abandoned
- 2002-11-12 EP EP02793925A patent/EP1453954A4/en not_active Ceased
- 2002-11-12 CZ CZ2004696A patent/CZ2004696A3/cs unknown
- 2002-11-12 CN CNA02823717XA patent/CN1596305A/zh active Pending
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2008
- 2008-02-14 JP JP2008033005A patent/JP2008194044A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
RU2351648C2 (ru) | 2009-04-10 |
EP1453954A2 (en) | 2004-09-08 |
HUP0500699A2 (hu) | 2005-11-28 |
HUP0500699A3 (en) | 2010-01-28 |
WO2003039489A2 (en) | 2003-05-15 |
MXPA04004311A (es) | 2005-03-31 |
EP1453954A4 (en) | 2004-12-15 |
KR20090115984A (ko) | 2009-11-10 |
CN1596305A (zh) | 2005-03-16 |
KR20050044393A (ko) | 2005-05-12 |
WO2003039489A3 (en) | 2004-01-29 |
JP2005533480A (ja) | 2005-11-10 |
JP2008194044A (ja) | 2008-08-28 |
AU2002359390A1 (en) | 2003-05-19 |
CA2465950A1 (en) | 2003-05-15 |
CZ2004696A3 (cs) | 2005-02-16 |
RU2004117530A (ru) | 2005-03-27 |
PL374557A1 (en) | 2005-10-31 |
US20030124721A1 (en) | 2003-07-03 |
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