ATE430807T1 - Verfahren zur kultivierung von circovirus - Google Patents

Verfahren zur kultivierung von circovirus

Info

Publication number
ATE430807T1
ATE430807T1 AT02712700T AT02712700T ATE430807T1 AT E430807 T1 ATE430807 T1 AT E430807T1 AT 02712700 T AT02712700 T AT 02712700T AT 02712700 T AT02712700 T AT 02712700T AT E430807 T1 ATE430807 T1 AT E430807T1
Authority
AT
Austria
Prior art keywords
circovirus
cultivation
methods
culturing
present
Prior art date
Application number
AT02712700T
Other languages
English (en)
Inventor
Qiang Liu
Suresh Tikoo
Philip Willson
Lorne Babiuk
Original Assignee
Univ Saskatchewan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Saskatchewan filed Critical Univ Saskatchewan
Application granted granted Critical
Publication of ATE430807T1 publication Critical patent/ATE430807T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10041Use of virus, viral particle or viral elements as a vector
    • C12N2750/10043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10051Methods of production or purification of viral material
    • C12N2750/10052Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
AT02712700T 2001-03-27 2002-03-27 Verfahren zur kultivierung von circovirus ATE430807T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27917301P 2001-03-27 2001-03-27
PCT/CA2002/000413 WO2002077210A2 (en) 2001-03-27 2002-03-27 Methods to culture circovirus

Publications (1)

Publication Number Publication Date
ATE430807T1 true ATE430807T1 (de) 2009-05-15

Family

ID=23067939

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02712700T ATE430807T1 (de) 2001-03-27 2002-03-27 Verfahren zur kultivierung von circovirus

Country Status (24)

Country Link
US (3) US6794163B2 (de)
EP (1) EP1379671B1 (de)
JP (1) JP4038127B2 (de)
KR (1) KR100876629B1 (de)
CN (2) CN1309836C (de)
AT (1) ATE430807T1 (de)
AU (1) AU2002244584B2 (de)
BR (1) BRPI0208456B8 (de)
CA (1) CA2442135C (de)
CY (1) CY1109267T1 (de)
CZ (1) CZ304525B6 (de)
DE (1) DE60232234D1 (de)
DK (1) DK1379671T3 (de)
ES (1) ES2324466T3 (de)
HU (1) HU228065B1 (de)
MX (1) MXPA03008810A (de)
MY (2) MY146518A (de)
PL (1) PL202951B1 (de)
PT (1) PT1379671E (de)
RU (2) RU2312142C2 (de)
SK (1) SK287969B6 (de)
UA (1) UA82647C2 (de)
WO (1) WO2002077210A2 (de)
ZA (1) ZA200307517B (de)

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US20040062775A1 (en) * 1997-12-05 2004-04-01 Agence Francaise De Securite Sanitaire Des Aliments Circovirus sequences associated with piglet weight loss disease (PWD)
FR2772047B1 (fr) * 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
ES2170622B1 (es) * 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
PT1379671E (pt) 2001-03-27 2009-07-20 Univ Saskatchewan Métodos de cultura de circovírus
US20030096377A1 (en) * 2001-06-28 2003-05-22 Virginia Tech Intellectual Properties, Inc. Differential PCR-RFLP assay for detecting and distinguishing between nonpathogenic PCV-1 and pathogenic PCV-2
US7276353B2 (en) 2001-12-12 2007-10-02 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US7279166B2 (en) 2001-12-12 2007-10-09 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7833707B2 (en) * 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
US8834891B2 (en) 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
HUE025994T2 (en) * 2005-12-29 2016-05-30 Boehringer Ingelheim Vetmedica Inc Use of PCV2 immunogenic composition to reduce clinical symptoms in piglets
PL1968630T3 (pl) 2005-12-29 2018-08-31 Boehringer Ingelheim Vetmedica, Inc. Multiwalentne immunogenne kompozycje PCV2
US20100129397A1 (en) * 2006-12-11 2010-05-27 Boehringer Ingelheim Vetmedica, Inc. Effective method of treatment of porcine circovirus and lawsonia intracellularis infections
TWI466682B (zh) * 2006-12-15 2015-01-01 Boehringer Ingelheim Vetmed 以豬第二型環狀病毒(pcv2)抗原治療豬
EP1941903A1 (de) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxe und Behandlung von PRDC
EP1958644A1 (de) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Vorbeugung und Behandlung von subklinischer PCVD
AU2007353480B2 (en) * 2007-05-11 2013-09-19 Temasek Life Sciences Laboratory Limited Production of a homogeneous cell line highly permissive to porcine circovirus type 2 (PCV2) infection
WO2008151215A1 (en) * 2007-06-04 2008-12-11 Merial Limited Production of porcine circovirus proteins in plants
US7829274B2 (en) * 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
UA99495C2 (ru) * 2007-12-21 2012-08-27 Вайет Ллк Изольованный цирковирус свиней, композиции и способы для иммунизации свиней против цирковируса свиней
WO2009088950A2 (en) * 2007-12-31 2009-07-16 Boehringer Ingelheim Vetmedica, Inc. Pcv2 orf2 virus like particle with foreign amino acid insertion
US20090317423A1 (en) * 2008-01-23 2009-12-24 Boehringer Ingelheim Vetmedica, Inc. Pcv2 mycoplasma hyopneumoniae immunogenic compositions and methods of producing such compositions
JP2011519273A (ja) * 2008-04-16 2011-07-07 ヴァージニア テック インテレクチュアル プロパティーズ,インコーポレーテッド キメラブタサーコウイルスPCV2Gen−1Repおよびその使用
TWI627281B (zh) * 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低pcv-2組合物殺病毒活性之方法及具有改良免疫原性之pcv-2組合物
EP2528931A4 (de) * 2010-01-25 2013-12-04 Blood Systems Inc Cyclovirus und verwendungsverfahren dafür
EP4091629A1 (de) 2013-09-25 2022-11-23 Zoetis Services LLC Divergente impfstoffzusammensetzung gegen pcv2b und verfahren zur verwendung
KR20220083861A (ko) 2013-10-02 2022-06-20 베링거 인겔하임 애니멀 헬스 유에스에이 인크. Pcv2 orf2 단백질 변이체 및 이로 이루어진 바이러스 유사 입자
MX2017014414A (es) 2015-05-14 2018-03-16 Merial Inc Metodo para la produccion de circovirus porcino y vacunas pcv2.
WO2018071511A1 (en) * 2016-10-11 2018-04-19 Orion Labs Group communication forwarding to a secondary service
CN114934020B (zh) * 2022-01-30 2024-02-13 山东省滨州畜牧兽医研究院 猪视网膜上皮细胞系及其建立方法和应用

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WO1998017799A1 (en) * 1996-10-23 1998-04-30 The Trustees Of The University Of Pennsylvania Immunotherapy and improved vaccines
AUPO856097A0 (en) 1997-08-14 1997-09-04 Commonwealth Scientific And Industrial Research Organisation Vector
US7192594B2 (en) 1997-10-03 2007-03-20 Merial Limited Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
FR2781159B1 (fr) 1998-07-06 2000-10-06 Merial Sas Vaccin circovirus et parvovirus porcin
UA78180C2 (uk) 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
US6517843B1 (en) * 1999-08-31 2003-02-11 Merial Reduction of porcine circovirus-2 viral load with inactivated PCV-2
US6391314B1 (en) 1997-10-03 2002-05-21 Merial Porcine circoviruses vaccines diagnostic reagents
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
EP1064024A4 (de) 1998-03-13 2005-04-06 Univ Georgia Res Found Impfstoffe gegen circovirus infektionen
US6492343B1 (en) 1998-04-15 2002-12-10 University Of Saskatchewan Porcine adenovirus type 3 genome
DE69941786D1 (de) 1998-09-08 2010-01-21 Brij P Giri Chemolumineszente 1,2-dioxetane
CA2349760C (en) 1998-11-02 2012-02-21 University Of Saskatchewan Bovine cells expressing adeno virus essential functions for propagation of recombinant adenoviral vectors
FR2789695B1 (fr) 1999-02-11 2003-03-07 Merial Sas Vecteurs et vaccins viraux a base d'adenovirus porcins recombines et replicatifs
US6943152B1 (en) 1999-06-10 2005-09-13 Merial DNA vaccine-PCV
US6497883B1 (en) 1999-06-10 2002-12-24 Merial Porcine circovirus recombinant poxvirus vaccine
EP1311698A2 (de) 2000-05-03 2003-05-21 University Of Guelph Schweine-adenovirus 5 vektor und impfstoff
PT1379671E (pt) 2001-03-27 2009-07-20 Univ Saskatchewan Métodos de cultura de circovírus

Also Published As

Publication number Publication date
KR20040002881A (ko) 2004-01-07
RU2003131342A (ru) 2005-04-20
US6794163B2 (en) 2004-09-21
BR0208456A (pt) 2004-03-02
KR100876629B1 (ko) 2009-01-07
CN1309836C (zh) 2007-04-11
CY1109267T1 (el) 2014-07-02
WO2002077210A2 (en) 2002-10-03
CN1840656A (zh) 2006-10-04
PL364077A1 (en) 2004-12-13
HU228065B1 (en) 2012-09-28
UA82647C2 (uk) 2008-05-12
DK1379671T3 (da) 2009-06-29
DE60232234D1 (de) 2009-06-18
ZA200307517B (en) 2004-09-27
JP2005500822A (ja) 2005-01-13
RU2007110808A (ru) 2008-09-27
CZ304525B6 (cs) 2014-06-18
CA2442135A1 (en) 2002-10-03
CN1840656B (zh) 2010-06-02
MY146518A (en) 2012-08-15
BRPI0208456B1 (pt) 2016-10-18
EP1379671A2 (de) 2004-01-14
CA2442135C (en) 2008-08-19
JP4038127B2 (ja) 2008-01-23
PT1379671E (pt) 2009-07-20
AU2002244584B2 (en) 2006-12-14
EP1379671B1 (de) 2009-05-06
RU2312142C2 (ru) 2007-12-10
CZ20032584A3 (en) 2004-03-17
HUP0500161A3 (en) 2010-01-28
CN1625598A (zh) 2005-06-08
MXPA03008810A (es) 2004-02-17
PL202951B1 (pl) 2009-08-31
SK12102003A3 (sk) 2004-05-04
US20070128700A1 (en) 2007-06-07
MY148759A (en) 2013-05-31
US7560278B2 (en) 2009-07-14
BRPI0208456B8 (pt) 2021-05-25
US7172899B2 (en) 2007-02-06
WO2002077210A3 (en) 2003-08-21
US20050239187A1 (en) 2005-10-27
SK287969B6 (sk) 2012-08-06
HUP0500161A2 (hu) 2005-05-30
ES2324466T3 (es) 2009-08-07
US20020177216A1 (en) 2002-11-28

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