ATE430807T1 - Verfahren zur kultivierung von circovirus - Google Patents

Verfahren zur kultivierung von circovirus

Info

Publication number
ATE430807T1
ATE430807T1 AT02712700T AT02712700T ATE430807T1 AT E430807 T1 ATE430807 T1 AT E430807T1 AT 02712700 T AT02712700 T AT 02712700T AT 02712700 T AT02712700 T AT 02712700T AT E430807 T1 ATE430807 T1 AT E430807T1
Authority
AT
Austria
Prior art keywords
circovirus
cultivation
methods
culturing
present
Prior art date
Application number
AT02712700T
Other languages
English (en)
Inventor
Qiang Liu
Suresh Tikoo
Philip Willson
Lorne Babiuk
Original Assignee
Univ Saskatchewan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Saskatchewan filed Critical Univ Saskatchewan
Application granted granted Critical
Publication of ATE430807T1 publication Critical patent/ATE430807T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10041Use of virus, viral particle or viral elements as a vector
    • C12N2750/10043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10051Methods of production or purification of viral material
    • C12N2750/10052Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT02712700T 2001-03-27 2002-03-27 Verfahren zur kultivierung von circovirus ATE430807T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27917301P 2001-03-27 2001-03-27
PCT/CA2002/000413 WO2002077210A2 (en) 2001-03-27 2002-03-27 Methods to culture circovirus

Publications (1)

Publication Number Publication Date
ATE430807T1 true ATE430807T1 (de) 2009-05-15

Family

ID=23067939

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02712700T ATE430807T1 (de) 2001-03-27 2002-03-27 Verfahren zur kultivierung von circovirus

Country Status (24)

Country Link
US (3) US6794163B2 (de)
EP (1) EP1379671B1 (de)
JP (1) JP4038127B2 (de)
KR (1) KR100876629B1 (de)
CN (2) CN1840656B (de)
AT (1) ATE430807T1 (de)
AU (1) AU2002244584B2 (de)
BR (1) BRPI0208456B8 (de)
CA (1) CA2442135C (de)
CY (1) CY1109267T1 (de)
CZ (1) CZ304525B6 (de)
DE (1) DE60232234D1 (de)
DK (1) DK1379671T3 (de)
ES (1) ES2324466T3 (de)
HU (1) HU228065B1 (de)
MX (1) MXPA03008810A (de)
MY (2) MY148759A (de)
PL (1) PL202951B1 (de)
PT (1) PT1379671E (de)
RU (2) RU2312142C2 (de)
SK (1) SK287969B6 (de)
UA (1) UA82647C2 (de)
WO (1) WO2002077210A2 (de)
ZA (1) ZA200307517B (de)

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US20040062775A1 (en) * 1997-12-05 2004-04-01 Agence Francaise De Securite Sanitaire Des Aliments Circovirus sequences associated with piglet weight loss disease (PWD)
FR2772047B1 (fr) * 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
ES2170622B1 (es) * 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
SK287969B6 (sk) * 2001-03-27 2012-08-06 University Of Saskatchewan Method to culture circovirus
US20030096377A1 (en) * 2001-06-28 2003-05-22 Virginia Tech Intellectual Properties, Inc. Differential PCR-RFLP assay for detecting and distinguishing between nonpathogenic PCV-1 and pathogenic PCV-2
US7279166B2 (en) 2001-12-12 2007-10-09 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US7276353B2 (en) 2001-12-12 2007-10-02 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7833707B2 (en) * 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
US8834891B2 (en) 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
DK3127551T3 (da) 2005-12-29 2020-10-12 Boehringer Ingelheim Animal Health Usa Inc Pcv2-immunogen-sammensætning til at mindske kliniske symptomer i grise
AU2006330491B2 (en) 2005-12-29 2011-08-18 Boehringer Ingelheim Animal Health USA Inc. Multivalent PCV2 immunogenic compositions and methods of producing such compositions
US20100129397A1 (en) * 2006-12-11 2010-05-27 Boehringer Ingelheim Vetmedica, Inc. Effective method of treatment of porcine circovirus and lawsonia intracellularis infections
DK2481420T3 (da) * 2006-12-15 2019-05-06 Boehringer Ingelheim Animal Health Usa Inc Enkeltdosis-anti-PCV2-svinevaccine
EP1941903A1 (de) * 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxe und Behandlung von PRDC
EP1958644A1 (de) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Vorbeugung und Behandlung von subklinischer PCVD
AU2007353480B2 (en) * 2007-05-11 2013-09-19 Temasek Life Sciences Laboratory Limited Production of a homogeneous cell line highly permissive to porcine circovirus type 2 (PCV2) infection
WO2008151215A1 (en) * 2007-06-04 2008-12-11 Merial Limited Production of porcine circovirus proteins in plants
US7829274B2 (en) * 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
RU2493254C9 (ru) * 2007-12-21 2013-12-20 ВАЙЕТ ЭлЭлСи Способы и композиции для иммунизации свиней против свиного цирковируса
AU2008347235A1 (en) * 2007-12-31 2009-07-16 Boehringer Ingelheim Vetmedica, Inc. PCV2 ORF2 virus like particle with foreign amino acid insertion
KR20100113582A (ko) * 2008-01-23 2010-10-21 베링거잉겔하임베트메디카인코퍼레이티드 Pcv2 마이코플라즈마 히오뉴모니에 면역원성 조성물 및 당해 조성물의 생산 방법
KR20100135903A (ko) * 2008-04-16 2010-12-27 버지니아 테크 인터렉추얼 프라퍼티스, 인크. 키메라 돼지 써코바이러스 PCV2Gen―1Rep 및 이의 용도
AR078253A1 (es) * 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
US20120100168A1 (en) * 2010-01-25 2012-04-26 Blood Systems, Inc. Cyclovirus and methods of use
KR102319843B1 (ko) 2013-09-25 2021-10-29 조에티스 서비시즈 엘엘씨 Pcv2b 분지형 백신 조성물 및 사용 방법
EA035265B1 (ru) 2013-10-02 2020-05-21 Бёрингер Ингельхайм Энимал Хелс Ю-Эс-Эй Инк. Вариант белка opc2 pcv2 и содержащие его вирусоподобные частицы
US9944904B2 (en) * 2015-05-14 2018-04-17 Merial Inc. Method for porcine circovirus production and PCV2 vaccines
WO2018071511A1 (en) * 2016-10-11 2018-04-19 Orion Labs Group communication forwarding to a secondary service
CN114934020B (zh) * 2022-01-30 2024-02-13 山东省滨州畜牧兽医研究院 猪视网膜上皮细胞系及其建立方法和应用

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WO1998017799A1 (en) * 1996-10-23 1998-04-30 The Trustees Of The University Of Pennsylvania Immunotherapy and improved vaccines
AUPO856097A0 (en) 1997-08-14 1997-09-04 Commonwealth Scientific And Industrial Research Organisation Vector
UA78180C2 (uk) 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
US6391314B1 (en) 1997-10-03 2002-05-21 Merial Porcine circoviruses vaccines diagnostic reagents
US7192594B2 (en) 1997-10-03 2007-03-20 Merial Limited Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
FR2781159B1 (fr) 1998-07-06 2000-10-06 Merial Sas Vaccin circovirus et parvovirus porcin
US6517843B1 (en) * 1999-08-31 2003-02-11 Merial Reduction of porcine circovirus-2 viral load with inactivated PCV-2
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
WO1999045956A1 (en) 1998-03-13 1999-09-16 University Of Georgia Research Foundation, Inc. Vaccines against circovirus infections
US6492343B1 (en) 1998-04-15 2002-12-10 University Of Saskatchewan Porcine adenovirus type 3 genome
EP1112274B1 (de) 1998-09-08 2009-12-09 Brij P. Giri Chemolumineszente 1,2-dioxetane
EP1127151A2 (de) * 1998-11-02 2001-08-29 University of Saskatchewan Bovine zellen,die essentielle adenovirale funktionen zur verfügung stellen, für die vermehrung von rekombinanten adenoviralen vektoren
FR2789695B1 (fr) 1999-02-11 2003-03-07 Merial Sas Vecteurs et vaccins viraux a base d'adenovirus porcins recombines et replicatifs
US6943152B1 (en) 1999-06-10 2005-09-13 Merial DNA vaccine-PCV
US6497883B1 (en) 1999-06-10 2002-12-24 Merial Porcine circovirus recombinant poxvirus vaccine
WO2001083737A2 (en) * 2000-05-03 2001-11-08 University Of Guelph Porcine adenovirus type 5 vector and vaccine
SK287969B6 (sk) * 2001-03-27 2012-08-06 University Of Saskatchewan Method to culture circovirus

Also Published As

Publication number Publication date
RU2312142C2 (ru) 2007-12-10
PT1379671E (pt) 2009-07-20
CA2442135A1 (en) 2002-10-03
HUP0500161A2 (hu) 2005-05-30
WO2002077210A3 (en) 2003-08-21
JP4038127B2 (ja) 2008-01-23
US7172899B2 (en) 2007-02-06
CY1109267T1 (el) 2014-07-02
DE60232234D1 (de) 2009-06-18
ES2324466T3 (es) 2009-08-07
RU2007110808A (ru) 2008-09-27
RU2003131342A (ru) 2005-04-20
SK12102003A3 (sk) 2004-05-04
US6794163B2 (en) 2004-09-21
JP2005500822A (ja) 2005-01-13
BR0208456A (pt) 2004-03-02
MY148759A (en) 2013-05-31
AU2002244584B2 (en) 2006-12-14
MY146518A (en) 2012-08-15
SK287969B6 (sk) 2012-08-06
CA2442135C (en) 2008-08-19
CZ20032584A3 (en) 2004-03-17
CN1625598A (zh) 2005-06-08
CN1840656A (zh) 2006-10-04
US7560278B2 (en) 2009-07-14
CN1840656B (zh) 2010-06-02
HU228065B1 (en) 2012-09-28
HUP0500161A3 (en) 2010-01-28
KR100876629B1 (ko) 2009-01-07
KR20040002881A (ko) 2004-01-07
CZ304525B6 (cs) 2014-06-18
BRPI0208456B8 (pt) 2021-05-25
EP1379671A2 (de) 2004-01-14
PL364077A1 (en) 2004-12-13
US20070128700A1 (en) 2007-06-07
ZA200307517B (en) 2004-09-27
MXPA03008810A (es) 2004-02-17
CN1309836C (zh) 2007-04-11
US20050239187A1 (en) 2005-10-27
DK1379671T3 (da) 2009-06-29
WO2002077210A2 (en) 2002-10-03
BRPI0208456B1 (pt) 2016-10-18
PL202951B1 (pl) 2009-08-31
US20020177216A1 (en) 2002-11-28
EP1379671B1 (de) 2009-05-06
UA82647C2 (uk) 2008-05-12

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