HUP0500161A2 - Cirkovírusok tenyésztésére szolgáló eljárás - Google Patents

Cirkovírusok tenyésztésére szolgáló eljárás

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Publication number
HUP0500161A2
HUP0500161A2 HU0500161A HUP0500161A HUP0500161A2 HU P0500161 A2 HUP0500161 A2 HU P0500161A2 HU 0500161 A HU0500161 A HU 0500161A HU P0500161 A HUP0500161 A HU P0500161A HU P0500161 A2 HUP0500161 A2 HU P0500161A2
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Hungary
Prior art keywords
mammalian
circovirus
methods
replication
cells
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HU0500161A
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English (en)
Inventor
Qiang Liu
Suresh K. Tikoo
Philip Willson
Lorne A. Babiuk
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University Of Saskatchewan
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Publication date
Application filed by University Of Saskatchewan filed Critical University Of Saskatchewan
Publication of HUP0500161A2 publication Critical patent/HUP0500161A2/hu
Publication of HUP0500161A3 publication Critical patent/HUP0500161A3/hu
Publication of HU228065B1 publication Critical patent/HU228065B1/hu

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    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10041Use of virus, viral particle or viral elements as a vector
    • C12N2750/10043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10051Methods of production or purification of viral material
    • C12N2750/10052Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A jelen találmány tárgyát emlős cirkovírusok tenyésztésére szolgálóeljárások képezik, amely eljárások tartalmazzák az alábbi lépéseket:a) olyan emlőssejtek biztosítása, amelyekben kifejeződik egy emlős-adenovírus E1 génjének a funkciója, és amely sejtek permisszívek azemlős cirkovírusok replikációja szempontjából; b) az emlős cirkovirus-genom - vagy egy replikációra alkalmas részének - a bejuttatása azemlített emlőssejtekbe; és c) az említett emlőssejtek tenyésztéseolyan körülmények között, amelyek megfelelőek az említettemlőscirkovírus replikációja szempontjából. Ó
HU0500161A 2001-03-27 2002-03-27 Methods to culture circovirus HU228065B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27917301P 2001-03-27 2001-03-27
PCT/CA2002/000413 WO2002077210A2 (en) 2001-03-27 2002-03-27 Methods to culture circovirus

Publications (3)

Publication Number Publication Date
HUP0500161A2 true HUP0500161A2 (hu) 2005-05-30
HUP0500161A3 HUP0500161A3 (en) 2010-01-28
HU228065B1 HU228065B1 (en) 2012-09-28

Family

ID=23067939

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0500161A HU228065B1 (en) 2001-03-27 2002-03-27 Methods to culture circovirus

Country Status (24)

Country Link
US (3) US6794163B2 (hu)
EP (1) EP1379671B1 (hu)
JP (1) JP4038127B2 (hu)
KR (1) KR100876629B1 (hu)
CN (2) CN1840656B (hu)
AT (1) ATE430807T1 (hu)
AU (1) AU2002244584B2 (hu)
BR (1) BRPI0208456B8 (hu)
CA (1) CA2442135C (hu)
CY (1) CY1109267T1 (hu)
CZ (1) CZ304525B6 (hu)
DE (1) DE60232234D1 (hu)
DK (1) DK1379671T3 (hu)
ES (1) ES2324466T3 (hu)
HU (1) HU228065B1 (hu)
MX (1) MXPA03008810A (hu)
MY (2) MY148759A (hu)
PL (1) PL202951B1 (hu)
PT (1) PT1379671E (hu)
RU (2) RU2312142C2 (hu)
SK (1) SK287969B6 (hu)
UA (1) UA82647C2 (hu)
WO (1) WO2002077210A2 (hu)
ZA (1) ZA200307517B (hu)

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US20040062775A1 (en) * 1997-12-05 2004-04-01 Agence Francaise De Securite Sanitaire Des Aliments Circovirus sequences associated with piglet weight loss disease (PWD)
ES2170622B1 (es) * 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
DK1379671T3 (da) 2001-03-27 2009-06-29 Univ Saskatchewan Fremgangsmåder til dyrkning af circovirus
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US7276353B2 (en) 2001-12-12 2007-10-02 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7833707B2 (en) 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
US8834891B2 (en) 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
JP5394750B2 (ja) * 2005-12-29 2014-01-22 ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド 多価pcv2免疫原性組成物及び当該組成物を製造する方法
MX338626B (es) 2005-12-29 2016-04-26 Boehringer Ingelheim Vetmed Uso de una composicion inmunogenica de pcv2 para producir los sintomas clinicos en cerdos.
WO2008073464A2 (en) 2006-12-11 2008-06-19 Boehringer Ingelheim Vetmedica, Inc. Effective method of treatment of porcine circovirus and lawsonia intracellularis infections
PL2481420T3 (pl) * 2006-12-15 2019-08-30 Boehringer Ingelheim Animal Health USA Inc. Jednodawkowa szczepionka anty-PCV2 dla świń
EP1941903A1 (en) * 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
DK2155246T3 (da) * 2007-05-11 2013-04-02 Temasek Life Sciences Lab Ltd Fremstilling af en homogen cellelinje højtolerant til porcine circovirus type 2 (pcv2)-infektion
WO2008151215A1 (en) * 2007-06-04 2008-12-11 Merial Limited Production of porcine circovirus proteins in plants
US7829274B2 (en) * 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
ME01156B (me) * 2007-12-21 2013-03-20 Zoetis Services Llc Postupci i kompozicije za imunizaciju svinja protiv svinjskog cirkovirusa
CN101932336B (zh) * 2007-12-31 2014-07-09 贝林格尔.英格海姆维特梅迪卡有限公司 有外来氨基酸插入的pcv2 orf2病毒样颗粒
CN101980720A (zh) 2008-01-23 2011-02-23 贝林格尔.英格海姆维特梅迪卡有限公司 Pcv2猪肺炎支原体致免疫组合物及其制备方法
BRPI0911200A2 (pt) * 2008-04-16 2016-07-05 Virginia Tech Intelectual Properties Inc circovírus suíno quimérico pcv2gen-1 rep e usos do mesmo
TWI627281B (zh) * 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低pcv-2組合物殺病毒活性之方法及具有改良免疫原性之pcv-2組合物
US20120100168A1 (en) * 2010-01-25 2012-04-26 Blood Systems, Inc. Cyclovirus and methods of use
BR112016006192A2 (pt) 2013-09-25 2017-09-26 Zoetis Services Llc composição de vacina de divergente de pcv2b e métodos de uso
ES2778425T3 (es) 2013-10-02 2020-08-10 Boehringer Ingelheim Animal Health Usa Inc Variante de la proteína ORF2 del PCV2 y partículas similares a virus compuestas por esta
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DK1379671T3 (da) 2001-03-27 2009-06-29 Univ Saskatchewan Fremgangsmåder til dyrkning af circovirus

Also Published As

Publication number Publication date
WO2002077210A3 (en) 2003-08-21
JP2005500822A (ja) 2005-01-13
BRPI0208456B8 (pt) 2021-05-25
BR0208456A (pt) 2004-03-02
US7560278B2 (en) 2009-07-14
BRPI0208456B1 (pt) 2016-10-18
KR100876629B1 (ko) 2009-01-07
ATE430807T1 (de) 2009-05-15
HU228065B1 (en) 2012-09-28
WO2002077210A2 (en) 2002-10-03
CN1840656A (zh) 2006-10-04
UA82647C2 (uk) 2008-05-12
US20050239187A1 (en) 2005-10-27
US7172899B2 (en) 2007-02-06
CZ20032584A3 (en) 2004-03-17
EP1379671B1 (en) 2009-05-06
SK12102003A3 (sk) 2004-05-04
AU2002244584B2 (en) 2006-12-14
PT1379671E (pt) 2009-07-20
CA2442135A1 (en) 2002-10-03
CZ304525B6 (cs) 2014-06-18
ZA200307517B (en) 2004-09-27
US20020177216A1 (en) 2002-11-28
DK1379671T3 (da) 2009-06-29
CN1625598A (zh) 2005-06-08
DE60232234D1 (de) 2009-06-18
MY148759A (en) 2013-05-31
KR20040002881A (ko) 2004-01-07
ES2324466T3 (es) 2009-08-07
CA2442135C (en) 2008-08-19
US20070128700A1 (en) 2007-06-07
US6794163B2 (en) 2004-09-21
MY146518A (en) 2012-08-15
CY1109267T1 (el) 2014-07-02
RU2003131342A (ru) 2005-04-20
EP1379671A2 (en) 2004-01-14
RU2312142C2 (ru) 2007-12-10
JP4038127B2 (ja) 2008-01-23
MXPA03008810A (es) 2004-02-17
SK287969B6 (sk) 2012-08-06
HUP0500161A3 (en) 2010-01-28
PL202951B1 (pl) 2009-08-31
RU2007110808A (ru) 2008-09-27
CN1309836C (zh) 2007-04-11
PL364077A1 (en) 2004-12-13
CN1840656B (zh) 2010-06-02

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