ATE342962T1 - Zusammensetzungen und verfahren für verbesserte zellkultur - Google Patents
Zusammensetzungen und verfahren für verbesserte zellkulturInfo
- Publication number
- ATE342962T1 ATE342962T1 AT00959455T AT00959455T ATE342962T1 AT E342962 T1 ATE342962 T1 AT E342962T1 AT 00959455 T AT00959455 T AT 00959455T AT 00959455 T AT00959455 T AT 00959455T AT E342962 T1 ATE342962 T1 AT E342962T1
- Authority
- AT
- Austria
- Prior art keywords
- cell culture
- methods
- compositions
- improved cell
- igf
- Prior art date
Links
- 238000004113 cell culture Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 abstract 1
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 abstract 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 230000019491 signal transduction Effects 0.000 abstract 1
- 230000014616 translation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0043—Medium free of human- or animal-derived components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/005—Protein-free medium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/105—Insulin-like growth factors [IGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15064599P | 1999-08-25 | 1999-08-25 | |
| US16894899P | 1999-12-03 | 1999-12-03 | |
| US17194999P | 1999-12-23 | 1999-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE342962T1 true ATE342962T1 (de) | 2006-11-15 |
Family
ID=27387011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00959455T ATE342962T1 (de) | 1999-08-25 | 2000-08-25 | Zusammensetzungen und verfahren für verbesserte zellkultur |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US6413744B1 (de) |
| EP (1) | EP1210411B1 (de) |
| JP (1) | JP2003507058A (de) |
| AT (1) | ATE342962T1 (de) |
| AU (1) | AU784506B2 (de) |
| CA (1) | CA2383073A1 (de) |
| CY (1) | CY1105772T1 (de) |
| DE (1) | DE60031419T2 (de) |
| DK (1) | DK1210411T3 (de) |
| ES (1) | ES2272318T3 (de) |
| IL (2) | IL148060A0 (de) |
| NZ (2) | NZ529329A (de) |
| PT (1) | PT1210411E (de) |
| WO (1) | WO2001014529A1 (de) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6475725B1 (en) | 1997-06-20 | 2002-11-05 | Baxter Aktiengesellschaft | Recombinant cell clones having increased stability and methods of making and using the same |
| US7115231B1 (en) | 1998-06-09 | 2006-10-03 | Symyx Technologies, Inc. | Parallel reactor with knife-edge seal |
| AT409379B (de) | 1999-06-02 | 2002-07-25 | Baxter Ag | Medium zur protein- und serumfreien kultivierung von zellen |
| ATE342962T1 (de) * | 1999-08-25 | 2006-11-15 | Immunex Corp | Zusammensetzungen und verfahren für verbesserte zellkultur |
| IL136232A0 (en) * | 2000-05-18 | 2001-05-20 | Bar Ilan University Res Author | Measurements of enzymatic activity in a single, individual cell in population |
| US6455007B1 (en) | 2000-06-13 | 2002-09-24 | Symyx Technologies, Inc. | Apparatus and method for testing compositions in contact with a porous medium |
| US6439036B1 (en) | 2000-06-13 | 2002-08-27 | Symyx Technologics, Inc. | Method for evaluating a test fluid |
| US7018589B1 (en) | 2000-07-19 | 2006-03-28 | Symyx Technologies, Inc. | High pressure parallel reactor |
| US7091004B1 (en) | 2001-06-08 | 2006-08-15 | Immunex Corporation | Regulation of translation for recombinant protein production |
| US20060073141A1 (en) * | 2001-06-28 | 2006-04-06 | Domantis Limited | Compositions and methods for treating inflammatory disorders |
| US20050271663A1 (en) * | 2001-06-28 | 2005-12-08 | Domantis Limited | Compositions and methods for treating inflammatory disorders |
| ES2344070T3 (es) * | 2001-07-04 | 2010-08-17 | Chromagenics B.V. | Secuencias de adn con actividad anti-represora. |
| WO2003035824A1 (en) * | 2001-10-25 | 2003-05-01 | Bar-Ilan University | Interactive transparent individual cells biochip processor |
| US20030166147A1 (en) * | 2001-12-14 | 2003-09-04 | Lee Chichang | Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media |
| JP2005532057A (ja) | 2002-07-09 | 2005-10-27 | バクスター・インターナショナル・インコーポレイテッド | 細胞を培養するための動物性タンパク質非含有培地 |
| AU2003290453A1 (en) * | 2002-12-20 | 2004-07-14 | Chromagenics B.V. | Means and methods for producing a protein through chromatin openers that are capable of rendering chromatin more accessible to transcription factors |
| IL154677A0 (en) * | 2003-02-27 | 2003-09-17 | Univ Bar Ilan | A method and apparatus for manipulating an individual cell |
| US7888110B2 (en) * | 2003-06-26 | 2011-02-15 | Seng Enterprises Ltd. | Pico liter well holding device and method of making the same |
| US8597597B2 (en) * | 2003-06-26 | 2013-12-03 | Seng Enterprises Ltd. | Picoliter well holding device and method of making the same |
| US9200245B2 (en) | 2003-06-26 | 2015-12-01 | Seng Enterprises Ltd. | Multiwell plate |
| EP1654347B1 (de) * | 2003-06-26 | 2014-06-04 | Seng Enterprises Limited | Verbesserte Materialien zur Konstruktion von Zellchips, Zellchip-Abdeckungen, Zellchip-Hüllen, prozessierte Zellchips und Verwendungen davon |
| US7982751B2 (en) * | 2003-07-11 | 2011-07-19 | The University Of North Carolina | Methods and systems for controlling a computer using a video image and for combining the video image with a computer desktop |
| US20050064524A1 (en) * | 2003-08-11 | 2005-03-24 | Mordechai Deutsch | Population of cells utilizable for substance detection and methods and devices using same |
| EP1711166A1 (de) * | 2004-02-03 | 2006-10-18 | Chemagis Ltd. | Stabile amorphe formen von montelukast natrium |
| US7403647B2 (en) * | 2004-09-13 | 2008-07-22 | Seng Enterprises Ltd. | Method for identifying an image of a well in an image of a well-bearing component |
| EP1763665A1 (de) * | 2004-07-07 | 2007-03-21 | Seng Enterprises Limited | Verfahren und vorrichtung zur identifizierung eines vertiefungsbildes auf einem bild einer komponente mit vertiefungen |
| WO2006021959A2 (en) * | 2004-08-25 | 2006-03-02 | Seng Enterprises Ltd. | Method and device for isolating cells |
| WO2006044594A2 (en) * | 2004-10-15 | 2006-04-27 | Monell Chemical Senses Center | Methods for culturing mammalian taste cells |
| US20060094104A1 (en) | 2004-10-29 | 2006-05-04 | Leopold Grillberger | Animal protein-free media for cultivation of cells |
| US20060195935A1 (en) | 2004-11-08 | 2006-08-31 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US8999667B2 (en) * | 2004-11-08 | 2015-04-07 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US20060172382A1 (en) * | 2004-11-08 | 2006-08-03 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| AU2005300503B2 (en) * | 2004-11-08 | 2010-12-16 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US20100136616A1 (en) * | 2004-11-08 | 2010-06-03 | Chromagenics B.V. | Selection of Host Cells Expressing Protein at High Levels |
| EP1844068A4 (de) * | 2005-01-25 | 2009-09-30 | Apollo Life Sciences Ltd | Moleküle und chimere moleküle davon |
| ES2352344T3 (es) | 2005-01-25 | 2011-02-17 | Seng Enterprises Limited | Dispositivo de microfluido para estudio de células. |
| EP1707634A1 (de) * | 2005-03-29 | 2006-10-04 | Octapharma AG | Verfahren zur Isolierung von rekombinant hergestellten Proteinen |
| US20060232821A1 (en) * | 2005-04-15 | 2006-10-19 | Sridharan Ranganathan | Parallel architecture for vector color error diffusion |
| WO2007002210A2 (en) * | 2005-06-20 | 2007-01-04 | Bresagen, Inc. | Embryonic stem cell culture compositions and methods of use thereof |
| EP1739179A1 (de) | 2005-06-30 | 2007-01-03 | Octapharma AG | Serumfreie stabile Transfektion und Produktion von rekombinanten humanen Proteinen in humanen Zelllinien |
| DE102005034043B4 (de) * | 2005-07-18 | 2019-12-12 | Südzucker Aktiengesellschaft Mannheim/Ochsenfurt | Gemisch, enthaltend L-Carnitin und Trehalulose, sowie Produkt enthaltend das Gemisch |
| US20070141555A1 (en) * | 2005-10-11 | 2007-06-21 | Mordechai Deutsch | Current damper for the study of cells |
| WO2007052245A1 (en) * | 2005-11-03 | 2007-05-10 | Seng Enterprises Ltd. | Method and device for studying floating, living cells |
| CA2633306A1 (en) | 2006-01-04 | 2007-07-12 | Baxter International Inc. | Oligopeptide-free cell culture media |
| US20060223999A1 (en) * | 2006-05-10 | 2006-10-05 | Chemagis Ltd. | Process for preparing montelukast and precursors thereof |
| US7807109B2 (en) | 2007-05-14 | 2010-10-05 | Freeslate, Inc. | Parallel batch reactor with pressure monitoring |
| US7655191B2 (en) | 2007-05-14 | 2010-02-02 | Symyx Solutions, Inc. | Methods for chemical reactions in a parallel batch reactor |
| WO2008149147A2 (en) * | 2007-06-06 | 2008-12-11 | Domantis Limited | Polypeptides, antibody variable domains and antagonists |
| MX2009012467A (es) * | 2007-06-29 | 2010-03-30 | Hoffmann La Roche | Celula de ovario de hamster chino. |
| MX2010003622A (es) * | 2007-10-12 | 2010-04-14 | Hoffmann La Roche | Expresion proteinica a partir de acidos nucleicos multiples. |
| US9975118B2 (en) | 2007-11-15 | 2018-05-22 | Seng Enterprises Ltd. | Device for the study of living cells |
| US9145540B1 (en) | 2007-11-15 | 2015-09-29 | Seng Enterprises Ltd. | Device for the study of living cells |
| US8563303B2 (en) * | 2008-03-19 | 2013-10-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Method for increasing recloning efficiency |
| CN102224239A (zh) * | 2008-09-26 | 2011-10-19 | 先灵公司 | 高效价抗体生产 |
| US8722615B2 (en) * | 2009-12-02 | 2014-05-13 | Acceleron Pharma, Inc. | Compositions and methods for increasing serum half-life |
| HRP20190138T1 (hr) | 2011-02-07 | 2019-03-22 | Cerenis Therapeutics Holding Sa | Lipoproteinski kompleksi i njihova proizvodnja i uporaba |
| US8883982B2 (en) | 2011-06-08 | 2014-11-11 | Acceleron Pharma, Inc. | Compositions and methods for increasing serum half-life |
| CN104822826B (zh) | 2012-10-15 | 2019-04-30 | 百时美施贵宝公司 | 用于蛋白产生的哺乳动物细胞培养过程 |
| WO2015010088A1 (en) * | 2013-07-19 | 2015-01-22 | Technical University Of Denmark | Methods for modeling chinese hamster ovary (cho) cell metabolism |
| UY36687A (es) | 2015-05-29 | 2016-11-30 | Bristol Myers Squibb Company Una Corporación Del Estado De Delaware | Anticuerpos contra ox40 y sus usos |
| CN113493770A (zh) * | 2020-03-18 | 2021-10-12 | 苏州大学 | 人源glut5稳定转染细胞株及其在筛选glut5抑制剂中的应用 |
| MX2023006998A (es) | 2020-12-22 | 2023-06-26 | Amgen Inc | Metodo de cultivo celular. |
| US20250230215A1 (en) * | 2021-11-08 | 2025-07-17 | Memorial Sloan-Kettering Cancer Center | Immune cells expressing glucose transporter 5 (glut5) and compositions and methods including the same |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL87737A (en) | 1987-09-11 | 1993-08-18 | Genentech Inc | Method for culturing polypeptide factor dependent vertebrate recombinant cells |
| WO1991003554A1 (en) * | 1989-09-01 | 1991-03-21 | Genentech, Inc. | Cells transfected with nucleic acid encoding gtp |
| US5605690A (en) | 1989-09-05 | 1997-02-25 | Immunex Corporation | Methods of lowering active TNF-α levels in mammals using tumor necrosis factor receptor |
| US5283173A (en) * | 1990-01-24 | 1994-02-01 | The Research Foundation Of State University Of New York | System to detect protein-protein interactions |
| EP0496453A1 (de) | 1991-01-23 | 1992-07-29 | Merck & Co. Inc. | Menschlicher glut4 Genpromotor |
| US5262308A (en) * | 1992-01-28 | 1993-11-16 | Thomas Jefferson University | Cell lines which constitutively express IGF-1 and IGF-1 R |
| WO1993020200A1 (en) | 1992-04-02 | 1993-10-14 | Imperial Cancer Research Technology Limited | Modified cells and method of treatment |
| US5663314A (en) | 1992-11-20 | 1997-09-02 | The Board Of Regents Of The University Of Washington | Human signal transduction MAPK kinase |
| EP0666312A1 (de) | 1994-02-08 | 1995-08-09 | Wolfgang A. Renner | Verfahren zur Förderung des Wachstums von Säugetierzellen |
| US5597719A (en) * | 1994-07-14 | 1997-01-28 | Onyx Pharmaceuticals, Inc. | Interaction of RAF-1 and 14-3-3 proteins |
| AUPN442295A0 (en) * | 1995-07-26 | 1995-08-17 | Commonwealth Scientific And Industrial Research Organisation | Regulated autocrine growth of mammalian cells |
| JP2001518302A (ja) | 1997-09-26 | 2001-10-16 | オニックス ファーマシューティカルズ,インコーポレイティド | Pkbキナーゼインヒビターを同定するための組成物及び方法 |
| ATE342962T1 (de) * | 1999-08-25 | 2006-11-15 | Immunex Corp | Zusammensetzungen und verfahren für verbesserte zellkultur |
-
2000
- 2000-08-25 AT AT00959455T patent/ATE342962T1/de not_active IP Right Cessation
- 2000-08-25 ES ES00959455T patent/ES2272318T3/es not_active Expired - Lifetime
- 2000-08-25 EP EP00959455A patent/EP1210411B1/de not_active Expired - Lifetime
- 2000-08-25 PT PT00959455T patent/PT1210411E/pt unknown
- 2000-08-25 NZ NZ529329A patent/NZ529329A/en unknown
- 2000-08-25 CA CA 2383073 patent/CA2383073A1/en not_active Abandoned
- 2000-08-25 NZ NZ517215A patent/NZ517215A/en unknown
- 2000-08-25 DK DK00959455T patent/DK1210411T3/da active
- 2000-08-25 AU AU70778/00A patent/AU784506B2/en not_active Ceased
- 2000-08-25 WO PCT/US2000/023483 patent/WO2001014529A1/en not_active Ceased
- 2000-08-25 DE DE2000631419 patent/DE60031419T2/de not_active Expired - Lifetime
- 2000-08-25 JP JP2001518843A patent/JP2003507058A/ja active Pending
- 2000-08-25 IL IL14806000A patent/IL148060A0/xx unknown
- 2000-08-25 US US09/648,667 patent/US6413744B1/en not_active Expired - Lifetime
-
2002
- 2002-02-06 IL IL148060A patent/IL148060A/en not_active IP Right Cessation
- 2002-03-29 US US10/109,971 patent/US6897040B2/en not_active Expired - Lifetime
-
2005
- 2005-02-28 US US11/069,122 patent/US7166445B2/en not_active Expired - Lifetime
-
2006
- 2006-11-13 CY CY20061101630T patent/CY1105772T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ517215A (en) | 2004-01-30 |
| WO2001014529A1 (en) | 2001-03-01 |
| ES2272318T3 (es) | 2007-05-01 |
| EP1210411A1 (de) | 2002-06-05 |
| US20050170462A1 (en) | 2005-08-04 |
| NZ529329A (en) | 2005-06-24 |
| JP2003507058A (ja) | 2003-02-25 |
| DE60031419D1 (de) | 2006-11-30 |
| WO2001014529A9 (en) | 2002-09-06 |
| IL148060A0 (en) | 2002-09-12 |
| DK1210411T3 (da) | 2007-02-19 |
| AU7077800A (en) | 2001-03-19 |
| CA2383073A1 (en) | 2001-03-01 |
| AU784506B2 (en) | 2006-04-13 |
| IL148060A (en) | 2009-07-20 |
| DE60031419T2 (de) | 2007-09-27 |
| US6413744B1 (en) | 2002-07-02 |
| US6897040B2 (en) | 2005-05-24 |
| CY1105772T1 (el) | 2011-02-02 |
| PT1210411E (pt) | 2006-12-29 |
| US7166445B2 (en) | 2007-01-23 |
| EP1210411B1 (de) | 2006-10-18 |
| US20020160455A1 (en) | 2002-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1210411 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |