DE60031419D1 - Zusammensetzungen und verfahren für verbesserte zellkultur - Google Patents

Zusammensetzungen und verfahren für verbesserte zellkultur

Info

Publication number
DE60031419D1
DE60031419D1 DE60031419T DE60031419T DE60031419D1 DE 60031419 D1 DE60031419 D1 DE 60031419D1 DE 60031419 T DE60031419 T DE 60031419T DE 60031419 T DE60031419 T DE 60031419T DE 60031419 D1 DE60031419 D1 DE 60031419D1
Authority
DE
Germany
Prior art keywords
cell culture
methods
compositions
improved cell
igf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60031419T
Other languages
English (en)
Other versions
DE60031419T2 (de
Inventor
E Morris
Pranhitha Reddy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunex Corp
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Application granted granted Critical
Publication of DE60031419D1 publication Critical patent/DE60031419D1/de
Publication of DE60031419T2 publication Critical patent/DE60031419T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0043—Medium free of human- or animal-derived components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/005—Protein-free medium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/105—Insulin-like growth factors [IGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE2000631419 1999-08-25 2000-08-25 Zusammensetzungen und verfahren für verbesserte zellkultur Expired - Lifetime DE60031419T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US15064599P 1999-08-25 1999-08-25
US150645P 1999-08-25
US16894899P 1999-12-03 1999-12-03
US168948P 1999-12-03
US17194999P 1999-12-23 1999-12-23
US171949P 1999-12-23
PCT/US2000/023483 WO2001014529A1 (en) 1999-08-25 2000-08-25 Compositions and methods for improved cell culture

Publications (2)

Publication Number Publication Date
DE60031419D1 true DE60031419D1 (de) 2006-11-30
DE60031419T2 DE60031419T2 (de) 2007-09-27

Family

ID=27387011

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2000631419 Expired - Lifetime DE60031419T2 (de) 1999-08-25 2000-08-25 Zusammensetzungen und verfahren für verbesserte zellkultur

Country Status (14)

Country Link
US (3) US6413744B1 (de)
EP (1) EP1210411B1 (de)
JP (1) JP2003507058A (de)
AT (1) ATE342962T1 (de)
AU (1) AU784506B2 (de)
CA (1) CA2383073A1 (de)
CY (1) CY1105772T1 (de)
DE (1) DE60031419T2 (de)
DK (1) DK1210411T3 (de)
ES (1) ES2272318T3 (de)
IL (2) IL148060A0 (de)
NZ (2) NZ529329A (de)
PT (1) PT1210411E (de)
WO (1) WO2001014529A1 (de)

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US6439036B1 (en) 2000-06-13 2002-08-27 Symyx Technologics, Inc. Method for evaluating a test fluid
US6455007B1 (en) 2000-06-13 2002-09-24 Symyx Technologies, Inc. Apparatus and method for testing compositions in contact with a porous medium
US7018589B1 (en) 2000-07-19 2006-03-28 Symyx Technologies, Inc. High pressure parallel reactor
US7091004B1 (en) 2001-06-08 2006-08-15 Immunex Corporation Regulation of translation for recombinant protein production
US20050271663A1 (en) * 2001-06-28 2005-12-08 Domantis Limited Compositions and methods for treating inflammatory disorders
US20060073141A1 (en) * 2001-06-28 2006-04-06 Domantis Limited Compositions and methods for treating inflammatory disorders
ES2344070T3 (es) * 2001-07-04 2010-08-17 Chromagenics B.V. Secuencias de adn con actividad anti-represora.
EP1438385A1 (de) * 2001-10-25 2004-07-21 Bar-Ilan University Interaktiver transparenter biochip-prozessor für einzeln adressierbare zellen
US20030166147A1 (en) * 2001-12-14 2003-09-04 Lee Chichang Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media
EP1520008B1 (de) 2002-07-09 2012-09-05 Baxter International Inc. Tierproteinfreies zellkulturmedium
EP1572994B1 (de) * 2002-12-20 2007-02-21 Chromagenics B.V. Mittel und methoden zur produktion eines proteins durch chromatin-öffner, die chromatin zugänglicher für transkriptionsfaktoren machen können
IL154677A0 (en) * 2003-02-27 2003-09-17 Univ Bar Ilan A method and apparatus for manipulating an individual cell
US7888110B2 (en) * 2003-06-26 2011-02-15 Seng Enterprises Ltd. Pico liter well holding device and method of making the same
US9200245B2 (en) 2003-06-26 2015-12-01 Seng Enterprises Ltd. Multiwell plate
US8597597B2 (en) * 2003-06-26 2013-12-03 Seng Enterprises Ltd. Picoliter well holding device and method of making the same
WO2004113492A1 (en) * 2003-06-26 2004-12-29 Molecular Cytomics Ltd. Improved materials for constructing cell-chips, cell-chip covers, cell-chip coats, processed cell-chips and uses thereof
US7982751B2 (en) * 2003-07-11 2011-07-19 The University Of North Carolina Methods and systems for controlling a computer using a video image and for combining the video image with a computer desktop
US20050064524A1 (en) * 2003-08-11 2005-03-24 Mordechai Deutsch Population of cells utilizable for substance detection and methods and devices using same
JP2007520546A (ja) * 2004-02-03 2007-07-26 ケマジス リミティド モンテルカストナトリウムの安定な非晶質性形態
US7403647B2 (en) * 2004-09-13 2008-07-22 Seng Enterprises Ltd. Method for identifying an image of a well in an image of a well-bearing component
EP1763665A1 (de) * 2004-07-07 2007-03-21 Seng Enterprises Limited Verfahren und vorrichtung zur identifizierung eines vertiefungsbildes auf einem bild einer komponente mit vertiefungen
US20080009051A1 (en) * 2004-08-25 2008-01-10 Seng Enterprises Ltd. Method and Device for Isolating Cells
EP1833961B1 (de) * 2004-10-15 2011-07-20 Monell Chemical Senses Center Verfahren zur kultivierung von geschmackszellen aus säugern
US20060094104A1 (en) 2004-10-29 2006-05-04 Leopold Grillberger Animal protein-free media for cultivation of cells
JP5291341B2 (ja) * 2004-11-08 2013-09-18 クロマジェニックス ベー ヴェー タンパク質を高レベルで発現する宿主細胞の選定
US20060195935A1 (en) 2004-11-08 2006-08-31 Chromagenics B.V. Selection of host cells expressing protein at high levels
US8999667B2 (en) * 2004-11-08 2015-04-07 Chromagenics B.V. Selection of host cells expressing protein at high levels
US20100136616A1 (en) * 2004-11-08 2010-06-03 Chromagenics B.V. Selection of Host Cells Expressing Protein at High Levels
SI1809750T1 (sl) 2004-11-08 2012-08-31 Chromagenics Bv Izbira gostiteljskih celic, ki imajo visok nivo izraĹľanja proteina
ES2352344T3 (es) * 2005-01-25 2011-02-17 Seng Enterprises Limited Dispositivo de microfluido para estudio de células.
EP1844068A4 (de) * 2005-01-25 2009-09-30 Apollo Life Sciences Ltd Moleküle und chimere moleküle davon
EP1707634A1 (de) 2005-03-29 2006-10-04 Octapharma AG Verfahren zur Isolierung von rekombinant hergestellten Proteinen
US20060232821A1 (en) * 2005-04-15 2006-10-19 Sridharan Ranganathan Parallel architecture for vector color error diffusion
WO2007002210A2 (en) * 2005-06-20 2007-01-04 Bresagen, Inc. Embryonic stem cell culture compositions and methods of use thereof
EP1739179A1 (de) 2005-06-30 2007-01-03 Octapharma AG Serumfreie stabile Transfektion und Produktion von rekombinanten humanen Proteinen in humanen Zelllinien
DE102005034043B4 (de) * 2005-07-18 2019-12-12 Südzucker Aktiengesellschaft Mannheim/Ochsenfurt Gemisch, enthaltend L-Carnitin und Trehalulose, sowie Produkt enthaltend das Gemisch
US20070141555A1 (en) * 2005-10-11 2007-06-21 Mordechai Deutsch Current damper for the study of cells
WO2007052245A1 (en) * 2005-11-03 2007-05-10 Seng Enterprises Ltd. Method and device for studying floating, living cells
PL3121266T3 (pl) 2006-01-04 2020-07-13 Baxalta Incorporated Wolne od oligopeptydów pożywki do hodowli komórkowej
US20060223999A1 (en) * 2006-05-10 2006-10-05 Chemagis Ltd. Process for preparing montelukast and precursors thereof
US7655191B2 (en) 2007-05-14 2010-02-02 Symyx Solutions, Inc. Methods for chemical reactions in a parallel batch reactor
US7807109B2 (en) 2007-05-14 2010-10-05 Freeslate, Inc. Parallel batch reactor with pressure monitoring
CA2683801A1 (en) * 2007-06-06 2008-12-11 Domantis Limited Polypeptides, antibody variable domains and antagonists
AU2008271657A1 (en) * 2007-06-29 2009-01-08 F. Hoffmann-La Roche Ag CHO cell
EP2207881A1 (de) * 2007-10-12 2010-07-21 F. Hoffmann-Roche AG Proteinexpression aus mehreren nukleinsäuren
US9145540B1 (en) 2007-11-15 2015-09-29 Seng Enterprises Ltd. Device for the study of living cells
US9975118B2 (en) 2007-11-15 2018-05-22 Seng Enterprises Ltd. Device for the study of living cells
WO2009115495A1 (de) * 2008-03-19 2009-09-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Methode zur steigerung der reklonierungseffizienz
CA2737580A1 (en) * 2008-09-26 2010-04-01 Schering Corporation High titer antibody production
JP2013512674A (ja) * 2009-12-02 2013-04-18 アクセルロン ファーマ， インコーポレイテッド Ｆｃ融合タンパク質の血清半減期を増加させるための組成物および方法
CA2826158A1 (en) 2011-02-07 2012-08-16 Rose ACKERMANN Lipoprotein complexes and manufacturing and uses thereof
EP2718328A4 (de) 2011-06-08 2014-12-24 Acceleron Pharma Inc Zusammensetzungen und verfahren zur erhöhung der halbwertszeit von serum
WO2014062535A1 (en) 2012-10-15 2014-04-24 Bristol-Myers Squibb Company Mammalian cell culture processes for protein production
WO2015010088A1 (en) * 2013-07-19 2015-01-22 Technical University Of Denmark Methods for modeling chinese hamster ovary (cho) cell metabolism
US9644032B2 (en) 2015-05-29 2017-05-09 Bristol-Myers Squibb Company Antibodies against OX40 and uses thereof
CN113493770A (zh) * 2020-03-18 2021-10-12 苏州大学 人源glut5稳定转染细胞株及其在筛选glut5抑制剂中的应用
JP2024503239A (ja) 2020-12-22 2024-01-25 アムジェン インコーポレイテッド 細胞培養法

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Also Published As

Publication number Publication date
ES2272318T3 (es) 2007-05-01
DE60031419T2 (de) 2007-09-27
ATE342962T1 (de) 2006-11-15
PT1210411E (pt) 2006-12-29
WO2001014529A9 (en) 2002-09-06
EP1210411B1 (de) 2006-10-18
US7166445B2 (en) 2007-01-23
IL148060A0 (en) 2002-09-12
IL148060A (en) 2009-07-20
CA2383073A1 (en) 2001-03-01
NZ517215A (en) 2004-01-30
AU784506B2 (en) 2006-04-13
US6413744B1 (en) 2002-07-02
CY1105772T1 (el) 2011-02-02
US6897040B2 (en) 2005-05-24
WO2001014529A1 (en) 2001-03-01
NZ529329A (en) 2005-06-24
US20050170462A1 (en) 2005-08-04
US20020160455A1 (en) 2002-10-31
JP2003507058A (ja) 2003-02-25
DK1210411T3 (da) 2007-02-19
AU7077800A (en) 2001-03-19
EP1210411A1 (de) 2002-06-05

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: IMMUNEX CORP., THOUSAND OAKS, CALIF., US

8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: DF-MP, 80333 MUENCHEN