ATE448322T1 - Erhöhte in vitro-synthese von aktiven, disulfidbrücken-enthaltenden proteinen - Google Patents
Erhöhte in vitro-synthese von aktiven, disulfidbrücken-enthaltenden proteinenInfo
- Publication number
- ATE448322T1 ATE448322T1 AT01968701T AT01968701T ATE448322T1 AT E448322 T1 ATE448322 T1 AT E448322T1 AT 01968701 T AT01968701 T AT 01968701T AT 01968701 T AT01968701 T AT 01968701T AT E448322 T1 ATE448322 T1 AT E448322T1
- Authority
- AT
- Austria
- Prior art keywords
- increased
- vitro synthesis
- disulfide bridge
- containing proteins
- bridge containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23038100P | 2000-09-06 | 2000-09-06 | |
| PCT/US2001/028159 WO2002020818A1 (en) | 2000-09-06 | 2001-09-06 | Enhanced in vitro synthesis of active proteins containing disulfide bonds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE448322T1 true ATE448322T1 (de) | 2009-11-15 |
Family
ID=22865001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01968701T ATE448322T1 (de) | 2000-09-06 | 2001-09-06 | Erhöhte in vitro-synthese von aktiven, disulfidbrücken-enthaltenden proteinen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6548276B2 (de) |
| EP (1) | EP1315826B1 (de) |
| JP (1) | JP4889185B2 (de) |
| AT (1) | ATE448322T1 (de) |
| AU (2) | AU2001288931B2 (de) |
| CA (1) | CA2419996C (de) |
| DE (1) | DE60140458D1 (de) |
| DK (1) | DK1315826T3 (de) |
| ES (1) | ES2334887T3 (de) |
| PT (1) | PT1315826E (de) |
| WO (1) | WO2002020818A1 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7041479B2 (en) * | 2000-09-06 | 2006-05-09 | The Board Of Trustess Of The Leland Stanford Junior University | Enhanced in vitro synthesis of active proteins containing disulfide bonds |
| US20050176157A1 (en) * | 2001-12-19 | 2005-08-11 | Elena Vasilyeva | Methods for detecting half-antibodies using chip-based gel electrophoresis |
| CA2477440A1 (en) * | 2002-02-28 | 2003-09-04 | Yaeta Endo | Reaction solution for cell-free protein synthesis, method of preparing the same and protein synthesis method using the same |
| JP5259046B2 (ja) | 2002-08-19 | 2013-08-07 | ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ | 改良されたインビトロ・タンパク質合成の方法 |
| KR100505744B1 (ko) * | 2003-02-15 | 2005-08-03 | 드림바이오젠 주식회사 | 단백질의 수용성 형태로의 생산을 위한 무세포단백질생산방법 |
| EP1685240B1 (de) | 2003-11-20 | 2014-12-31 | The Board of Trustees of the Leland Stanford Junior University | Verbesserte verfahren zur in-vitro-proteinsynthese |
| WO2005052567A1 (en) * | 2003-11-24 | 2005-06-09 | Biogen Idec Ma Inc. | Methods for detecting half-antibodies using chip-based gel electrophoresis |
| EP1757688A4 (de) * | 2004-04-30 | 2009-07-08 | Post Genome Inst Co Ltd | Verfahren des disulfidquervernetzungsbildungstyps in der in-vitro-proteinsynthese |
| DE102004032460B3 (de) * | 2004-06-30 | 2005-08-18 | Rina-Netzwerk Rna Technologien Gmbh | Verfahren zur präparativen in vitro Proteinbiosynthese |
| US20070117179A1 (en) * | 2005-09-27 | 2007-05-24 | Invitrogen Corporation | In vitro protein synthesis systems for membrane proteins that include adolipoproteins and phospholipid-adolipoprotein particles |
| US20080248565A1 (en) * | 2007-03-01 | 2008-10-09 | Invitrogen Corporation | Isolated phospholipid-protein particles |
| CA2673765A1 (en) * | 2007-01-18 | 2008-07-24 | The Board Of Trustees Of The Leland Stanford Junior University | Enhanced cell-free synthesis of active proteins containing disulfide bonds |
| US20090053786A1 (en) | 2007-07-09 | 2009-02-26 | Yung-Hsiang Kao | Prevention of disulfide bond reduction during recombinant production of polypeptides |
| US9637746B2 (en) | 2008-12-15 | 2017-05-02 | Greenlight Biosciences, Inc. | Methods for control of flux in metabolic pathways |
| CN105132387A (zh) * | 2008-12-22 | 2015-12-09 | 绿光生物科学公司 | 用于制造化合物的组合物和方法 |
| CN102051406A (zh) * | 2009-11-03 | 2011-05-11 | 凯熙医药(武汉)有限公司 | 一种用于预报人体发生异常增殖或肿瘤发生风险的检测方法 |
| EP2566953B1 (de) | 2010-05-07 | 2019-01-02 | Greenlight Biosciences, Inc. | Verfahren zur flusssteuerung bei stoffwechselwegen druch enzymumpositionierung |
| WO2012030980A1 (en) | 2010-08-31 | 2012-03-08 | Greenlight Biosciences, Inc. | Methods for control of flux in metabolic pathways through protease manipulation |
| EP2753702B1 (de) | 2011-09-09 | 2021-12-15 | GreenLight Biosciences, Inc. | Zellfreie herstellung von carbapenemen |
| SG11201504930PA (en) | 2012-12-21 | 2015-07-30 | Greenlight Biosciences Inc | Cell-free system for converting methane into fuel, pyruvate or isobutanol |
| CA2936092A1 (en) | 2013-01-23 | 2014-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Stabilized hepatitis b core polypeptide |
| DK3030671T3 (en) | 2013-08-05 | 2019-01-21 | Greenlight Biosciences Inc | MODIFIED PROTEINS WITH A PROTEASE CLEANING PLACE |
| KR20230048162A (ko) | 2015-03-30 | 2023-04-10 | 그린라이트 바이오사이언시스, 아이엔씨. | 리보핵산의 무세포 생산 |
| AU2017246458B2 (en) | 2016-04-06 | 2022-08-11 | Greenlight Biosciences, Inc. | Cell-free production of ribonucleic acid |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| BR112019013853A2 (pt) | 2017-01-06 | 2020-01-28 | Greenlight Biosciences Inc | produção de açúcares isentos de células |
| WO2019035916A1 (en) | 2017-08-15 | 2019-02-21 | Northwestern University | DESIGN OF PROTEIN GLYCOSYLATION SITES BY RAPID EXPRESSION AND CHARACTERIZATION OF N-GLYCOSYLTRANSFERASES |
| IL273887B (en) | 2017-10-11 | 2022-09-01 | Greenlight Biosciences Inc | Methods and preparations for the production of nucleoside triphosphate and ribonucleic acid |
| WO2019094859A1 (en) | 2017-11-10 | 2019-05-16 | Northwestern University | Cell-free protein synthesis platform derived from cellular extracts of vibrio natriegens |
| US11725224B2 (en) | 2018-04-16 | 2023-08-15 | Northwestern University | Methods for co-activating in vitro non-standard amino acid (nsAA) incorporation and glycosylation in crude cell lysates |
| WO2020040840A2 (en) | 2018-06-01 | 2020-02-27 | Northwestern University | Expanding the chemical substrates for genetic code reprogramming |
| CN114026107A (zh) * | 2019-04-16 | 2022-02-08 | 巴克姆股份公司 | 二硫键肽的生产 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6027888A (en) * | 1996-04-05 | 2000-02-22 | Board Of Regents, The University Of Texas System | Methods for producing soluble, biologically-active disulfide-bond containing eukaryotic proteins in bacterial cells |
-
2001
- 2001-09-05 US US09/948,052 patent/US6548276B2/en not_active Expired - Lifetime
- 2001-09-06 AU AU2001288931A patent/AU2001288931B2/en not_active Expired
- 2001-09-06 DK DK01968701.1T patent/DK1315826T3/da active
- 2001-09-06 CA CA2419996A patent/CA2419996C/en not_active Expired - Lifetime
- 2001-09-06 WO PCT/US2001/028159 patent/WO2002020818A1/en active Application Filing
- 2001-09-06 EP EP01968701A patent/EP1315826B1/de not_active Expired - Lifetime
- 2001-09-06 AT AT01968701T patent/ATE448322T1/de active
- 2001-09-06 ES ES01968701T patent/ES2334887T3/es not_active Expired - Lifetime
- 2001-09-06 DE DE60140458T patent/DE60140458D1/de not_active Expired - Lifetime
- 2001-09-06 PT PT01968701T patent/PT1315826E/pt unknown
- 2001-09-06 AU AU8893101A patent/AU8893101A/xx active Pending
- 2001-09-06 JP JP2002525824A patent/JP4889185B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE60140458D1 (de) | 2009-12-24 |
| US20020058303A1 (en) | 2002-05-16 |
| AU8893101A (en) | 2002-03-22 |
| EP1315826A4 (de) | 2004-08-04 |
| CA2419996A1 (en) | 2002-03-14 |
| PT1315826E (pt) | 2010-02-19 |
| EP1315826B1 (de) | 2009-11-11 |
| CA2419996C (en) | 2012-11-06 |
| AU2001288931B2 (en) | 2006-08-10 |
| EP1315826A1 (de) | 2003-06-04 |
| DK1315826T3 (da) | 2010-03-22 |
| ES2334887T3 (es) | 2010-03-17 |
| JP4889185B2 (ja) | 2012-03-07 |
| WO2002020818A1 (en) | 2002-03-14 |
| US6548276B2 (en) | 2003-04-15 |
| JP2004508050A (ja) | 2004-03-18 |
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| UEP | Publication of translation of european patent specification |
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