DK1315826T3 - Forøget in vitro syntese af aktive proteiner indeholdende disulfidbindinger - Google Patents
Forøget in vitro syntese af aktive proteiner indeholdende disulfidbindingerInfo
- Publication number
- DK1315826T3 DK1315826T3 DK01968701.1T DK01968701T DK1315826T3 DK 1315826 T3 DK1315826 T3 DK 1315826T3 DK 01968701 T DK01968701 T DK 01968701T DK 1315826 T3 DK1315826 T3 DK 1315826T3
- Authority
- DK
- Denmark
- Prior art keywords
- disulfide bonds
- increased
- containing disulfide
- vitro synthesis
- proteins containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23038100P | 2000-09-06 | 2000-09-06 | |
| PCT/US2001/028159 WO2002020818A1 (en) | 2000-09-06 | 2001-09-06 | Enhanced in vitro synthesis of active proteins containing disulfide bonds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1315826T3 true DK1315826T3 (da) | 2010-03-22 |
Family
ID=22865001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01968701.1T DK1315826T3 (da) | 2000-09-06 | 2001-09-06 | Forøget in vitro syntese af aktive proteiner indeholdende disulfidbindinger |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6548276B2 (da) |
| EP (1) | EP1315826B1 (da) |
| JP (1) | JP4889185B2 (da) |
| AT (1) | ATE448322T1 (da) |
| AU (2) | AU8893101A (da) |
| CA (1) | CA2419996C (da) |
| DE (1) | DE60140458D1 (da) |
| DK (1) | DK1315826T3 (da) |
| ES (1) | ES2334887T3 (da) |
| PT (1) | PT1315826E (da) |
| WO (1) | WO2002020818A1 (da) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7041479B2 (en) * | 2000-09-06 | 2006-05-09 | The Board Of Trustess Of The Leland Stanford Junior University | Enhanced in vitro synthesis of active proteins containing disulfide bonds |
| US20050176157A1 (en) * | 2001-12-19 | 2005-08-11 | Elena Vasilyeva | Methods for detecting half-antibodies using chip-based gel electrophoresis |
| US7273615B2 (en) * | 2002-02-28 | 2007-09-25 | Cellfree Sciences Co., Ltd. | Reaction solution for cell-free protein synthesis, method of preparing the same, and protein synthesis method using the same |
| ATE445699T1 (de) | 2002-08-19 | 2009-10-15 | Univ Leland Stanford Junior | Verbesserte verfahren zur in-vitro- proteinsynthese |
| KR100505744B1 (ko) * | 2003-02-15 | 2005-08-03 | 드림바이오젠 주식회사 | 단백질의 수용성 형태로의 생산을 위한 무세포단백질생산방법 |
| ES2532608T3 (es) | 2003-11-20 | 2015-03-30 | The Board Of Trustees Of The Leland Stanford Junior University | Métodos mejorados de síntesis proteica in vitro |
| WO2005052567A1 (en) * | 2003-11-24 | 2005-06-09 | Biogen Idec Ma Inc. | Methods for detecting half-antibodies using chip-based gel electrophoresis |
| KR20070015216A (ko) * | 2004-04-30 | 2007-02-01 | 가부시키가이샤 포스트 게놈 겐큐쇼 | 디술피드 가교 형성형 시험관내 단백질 합성 방법 |
| DE102004032460B3 (de) * | 2004-06-30 | 2005-08-18 | Rina-Netzwerk Rna Technologien Gmbh | Verfahren zur präparativen in vitro Proteinbiosynthese |
| US20070117179A1 (en) * | 2005-09-27 | 2007-05-24 | Invitrogen Corporation | In vitro protein synthesis systems for membrane proteins that include adolipoproteins and phospholipid-adolipoprotein particles |
| WO2008088884A2 (en) * | 2007-01-18 | 2008-07-24 | The Board Of Trustees Of The Leland Stanford Junior University | Enhanced cell-free synthesis of active proteins containing disulfide bonds |
| WO2008106660A2 (en) * | 2007-03-01 | 2008-09-04 | Invitrogen Corporation | Isolated phospholipid-protein particles |
| LT3597659T (lt) | 2007-07-09 | 2023-05-10 | Genentech, Inc. | Disulfidinės jungties redukcijos prevencijos būdas gaminant polipeptidą rekombinantiniu būdu |
| WO2010077806A1 (en) | 2008-12-15 | 2010-07-08 | Greenlight Biosciences, Inc. | Methods for control of flux in metabolic pathways |
| US20110008867A1 (en) * | 2008-12-22 | 2011-01-13 | Greenlight Biosciences | Compositions and methods for the production of a compound |
| CN102051406A (zh) * | 2009-11-03 | 2011-05-11 | 凯熙医药(武汉)有限公司 | 一种用于预报人体发生异常增殖或肿瘤发生风险的检测方法 |
| DK2566953T3 (da) | 2010-05-07 | 2019-04-15 | Greenlight Biosciences Inc | Fremgangsmåder til styring af strømmen ad metaboliske veje ved hjælp af enzymrelokering |
| DK3219796T3 (da) | 2010-08-31 | 2020-12-21 | Greenlight Biosciences Inc | Fremgangsmåder til kontrol af strømningen i metaboliske reaktionsveje ved hjælp af proteasemanipulation |
| SG2014014377A (en) | 2011-09-09 | 2014-05-29 | Greenlight Biosciences Inc | Cell-free preparation of carbapenems |
| EP2935598A1 (en) | 2012-12-21 | 2015-10-28 | Greenlight Biosciences Inc. | Cell-free system for converting methane into fuel, pyruvate or isobutanol |
| CA2936092A1 (en) | 2013-01-23 | 2014-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Stabilized hepatitis b core polypeptide |
| KR20160037194A (ko) | 2013-08-05 | 2016-04-05 | 그린라이트 바이오사이언시스, 아이엔씨. | 프로테아제 분열 위치를 갖는 엔지니어링된 프로테인 |
| SG11201707370WA (en) | 2015-03-30 | 2017-10-30 | Greenlight Biosciences Inc | Cell-free production of ribonucleic acid |
| JP7011599B2 (ja) | 2016-04-06 | 2022-02-10 | グリーンライト バイオサイエンシーズ インコーポレーテッド | リボ核酸の無細胞的生産 |
| US11998599B2 (en) | 2016-12-30 | 2024-06-04 | Vaxcyte, Inc. | Polypeptide-antigen conjugates with non-natural amino acids |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| WO2018129275A1 (en) | 2017-01-06 | 2018-07-12 | Greenlight Biosciences, Inc. | Cell-free production of sugars |
| WO2019035916A1 (en) | 2017-08-15 | 2019-02-21 | Northwestern University | DESIGN OF PROTEIN GLYCOSYLATION SITES BY RAPID EXPRESSION AND CHARACTERIZATION OF N-GLYCOSYLTRANSFERASES |
| CN111465701A (zh) | 2017-10-11 | 2020-07-28 | 绿光生物科技股份有限公司 | 用于三磷酸核苷和核糖核酸生成的方法和组合物 |
| US11673921B2 (en) | 2017-11-10 | 2023-06-13 | Northwestern University | Cell-free protein synthesis platform derived from cellular extracts of Vibrio natriegens |
| WO2019204346A1 (en) | 2018-04-16 | 2019-10-24 | Northwestern University | METHODS FOR CO-ACTIVATING IN VITRO NON-STANDARD AMINO ACID (nsAA) INCORPORATION AND GLYCOSYLATION IN CRUDE CELLLYSATES |
| US11814621B2 (en) | 2018-06-01 | 2023-11-14 | Northwestern University | Expanding the chemical substrates for genetic code reprogramming |
| US20220213139A1 (en) * | 2019-04-16 | 2022-07-07 | Bachem Holding Ag | Manufacture of disulfide bonded peptides |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997038123A1 (en) * | 1996-04-05 | 1997-10-16 | Board Of Regents, The University Of Texas System | Methods for producing soluble, biologically-active disulfide bond-containing eukaryotic proteins in bacterial cells |
-
2001
- 2001-09-05 US US09/948,052 patent/US6548276B2/en not_active Expired - Lifetime
- 2001-09-06 PT PT01968701T patent/PT1315826E/pt unknown
- 2001-09-06 ES ES01968701T patent/ES2334887T3/es not_active Expired - Lifetime
- 2001-09-06 JP JP2002525824A patent/JP4889185B2/ja not_active Expired - Lifetime
- 2001-09-06 AU AU8893101A patent/AU8893101A/xx active Pending
- 2001-09-06 WO PCT/US2001/028159 patent/WO2002020818A1/en active Application Filing
- 2001-09-06 DE DE60140458T patent/DE60140458D1/de not_active Expired - Lifetime
- 2001-09-06 CA CA2419996A patent/CA2419996C/en not_active Expired - Lifetime
- 2001-09-06 AT AT01968701T patent/ATE448322T1/de active
- 2001-09-06 AU AU2001288931A patent/AU2001288931B2/en not_active Expired
- 2001-09-06 EP EP01968701A patent/EP1315826B1/en not_active Expired - Lifetime
- 2001-09-06 DK DK01968701.1T patent/DK1315826T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| US6548276B2 (en) | 2003-04-15 |
| PT1315826E (pt) | 2010-02-19 |
| JP2004508050A (ja) | 2004-03-18 |
| ES2334887T3 (es) | 2010-03-17 |
| CA2419996C (en) | 2012-11-06 |
| US20020058303A1 (en) | 2002-05-16 |
| AU2001288931B2 (en) | 2006-08-10 |
| EP1315826B1 (en) | 2009-11-11 |
| ATE448322T1 (de) | 2009-11-15 |
| EP1315826A1 (en) | 2003-06-04 |
| JP4889185B2 (ja) | 2012-03-07 |
| CA2419996A1 (en) | 2002-03-14 |
| EP1315826A4 (en) | 2004-08-04 |
| AU8893101A (en) | 2002-03-22 |
| WO2002020818A1 (en) | 2002-03-14 |
| DE60140458D1 (de) | 2009-12-24 |
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