DE602005016024D1 - Synthese von peptid t-1249 mit peptidzwischenproduktfragmenten - Google Patents

Synthese von peptid t-1249 mit peptidzwischenproduktfragmenten

Info

Publication number
DE602005016024D1
DE602005016024D1 DE602005016024T DE602005016024T DE602005016024D1 DE 602005016024 D1 DE602005016024 D1 DE 602005016024D1 DE 602005016024 T DE602005016024 T DE 602005016024T DE 602005016024 T DE602005016024 T DE 602005016024T DE 602005016024 D1 DE602005016024 D1 DE 602005016024D1
Authority
DE
Germany
Prior art keywords
peptide
synthesis
intermediate fragments
peptide intermediates
fragments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005016024T
Other languages
English (en)
Inventor
Yeun-Kwei Han
Mark L Hodges
David A Johnston
Hiralal N Khatri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE602005016024D1 publication Critical patent/DE602005016024D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE602005016024T 2004-12-30 2005-12-22 Synthese von peptid t-1249 mit peptidzwischenproduktfragmenten Active DE602005016024D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64071604P 2004-12-30 2004-12-30
PCT/EP2005/013854 WO2006069729A1 (en) 2004-12-30 2005-12-22 Synthesis of peptide t-1249 using peptide intermediate fragments

Publications (1)

Publication Number Publication Date
DE602005016024D1 true DE602005016024D1 (de) 2009-09-24

Family

ID=36001047

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005016024T Active DE602005016024D1 (de) 2004-12-30 2005-12-22 Synthese von peptid t-1249 mit peptidzwischenproduktfragmenten

Country Status (9)

Country Link
US (1) US7544665B2 (de)
EP (1) EP1856142B1 (de)
JP (1) JP4886703B2 (de)
CN (1) CN101133076B (de)
AT (1) ATE439371T1 (de)
CA (1) CA2593866C (de)
DE (1) DE602005016024D1 (de)
ES (1) ES2329270T3 (de)
WO (1) WO2006069729A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE445636T1 (de) * 2004-12-30 2009-10-15 Hoffmann La Roche Synthese des peptides t-20 aus peptidfragmenten als zwischenprodukte
DK2205624T3 (da) * 2007-10-27 2017-01-02 Corden Pharma Colorado Inc Insulinotropisk peptidsyntese under anvendelse af faststof- og opløsningsfasekombinationsteknikker
KR20100102652A (ko) * 2007-12-11 2010-09-24 에프. 호프만-라 로슈 아게 고체- 및 용액-상 조합 기법을 사용한 인슐린친화성 펩타이드 합성
DE102008017645A1 (de) 2008-04-04 2009-10-08 Carl Zeiss Smt Ag Vorrichtung zur mikrolithographischen Projektionsbelichtung sowie Vorrichtung zur Inspektion einer Oberfläche eines Substrats

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994002505A1 (en) 1992-07-20 1994-02-03 Duke University Compounds which inhibit hiv replication
US6281335B1 (en) 1993-10-08 2001-08-28 Coulter Corporation Hybridoma and anti-KC-4 humanized monoclonal antibody
US5464933A (en) 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission
US6479055B1 (en) 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
US6281331B1 (en) * 1998-03-23 2001-08-28 Trimeris, Inc. Methods and compositions for peptide synthesis
US6469136B1 (en) * 1999-07-07 2002-10-22 Trimeris, Inc. Methods and composition for peptide synthesis
US20040209999A1 (en) * 2002-08-16 2004-10-21 Bohling James Charles Method of manufacturing polypeptides, including T-20 and T-1249, at commercial scale, and polypeptide compositions related thereto
AU2004200485A1 (en) * 2003-02-25 2004-09-09 Rohm And Haas Company Method of manufacturing T-20 and T-1249 peptides at commercial scale, and T-20 and T-1249 compositions related thereto
ATE445636T1 (de) 2004-12-30 2009-10-15 Hoffmann La Roche Synthese des peptides t-20 aus peptidfragmenten als zwischenprodukte

Also Published As

Publication number Publication date
CA2593866C (en) 2013-08-06
US20060173163A1 (en) 2006-08-03
EP1856142B1 (de) 2009-08-12
WO2006069729A1 (en) 2006-07-06
ATE439371T1 (de) 2009-08-15
ES2329270T3 (es) 2009-11-24
EP1856142A1 (de) 2007-11-21
CN101133076B (zh) 2011-07-13
JP2008526699A (ja) 2008-07-24
US7544665B2 (en) 2009-06-09
JP4886703B2 (ja) 2012-02-29
CA2593866A1 (en) 2006-07-06
CN101133076A (zh) 2008-02-27

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Legal Events

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