DK1537229T3 - Fremgangsmåder til produktion af biologiske stoffer i pigmentmanglende mutanter af Bacillus-celler - Google Patents

Fremgangsmåder til produktion af biologiske stoffer i pigmentmanglende mutanter af Bacillus-celler

Info

Publication number
DK1537229T3
DK1537229T3 DK03771884.8T DK03771884T DK1537229T3 DK 1537229 T3 DK1537229 T3 DK 1537229T3 DK 03771884 T DK03771884 T DK 03771884T DK 1537229 T3 DK1537229 T3 DK 1537229T3
Authority
DK
Denmark
Prior art keywords
pigment
methods
biological agents
bacillus cells
deficient mutants
Prior art date
Application number
DK03771884.8T
Other languages
English (en)
Inventor
Maria Tang
David Sternberg
Alan Sloma
Regine Behr
Original Assignee
Novozymes Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes Inc filed Critical Novozymes Inc
Application granted granted Critical
Publication of DK1537229T3 publication Critical patent/DK1537229T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK03771884.8T 2002-07-26 2003-07-25 Fremgangsmåder til produktion af biologiske stoffer i pigmentmanglende mutanter af Bacillus-celler DK1537229T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39885302P 2002-07-26 2002-07-26
PCT/US2003/023398 WO2004011609A2 (en) 2002-07-26 2003-07-25 Methods for producing biological substances in pigment-deficient mutants of bacillus cells

Publications (1)

Publication Number Publication Date
DK1537229T3 true DK1537229T3 (da) 2013-12-02

Family

ID=31188506

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03771884.8T DK1537229T3 (da) 2002-07-26 2003-07-25 Fremgangsmåder til produktion af biologiske stoffer i pigmentmanglende mutanter af Bacillus-celler

Country Status (6)

Country Link
US (3) US7476516B2 (da)
EP (1) EP1537229B1 (da)
CN (1) CN100567501C (da)
AU (1) AU2003254196A1 (da)
DK (1) DK1537229T3 (da)
WO (1) WO2004011609A2 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007101498A (ja) * 2005-10-07 2007-04-19 Fujifilm Corp 蛍光プローブ及び蛍光検出方法
EP2021357B1 (en) * 2006-04-26 2011-06-08 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Cyclodipeptide synthetases and their use for synthesis of cyclo(leu-leu) cyclodipeptide
WO2008066931A2 (en) * 2006-11-29 2008-06-05 Novozymes, Inc. Bacillus licheniformis chromosome
EP2212419A1 (en) * 2007-10-31 2010-08-04 Kyowa Hakko Bio Co., Ltd. Cyclodipeptide synthases (cdss) and their use in the synthesis of linear dipeptides
CN101935679A (zh) * 2010-03-04 2011-01-05 上海交通大学 基于革兰氏阳性安全微生物的透明质酸的异源合成方法
CN103451235B (zh) * 2013-06-06 2015-02-11 徐州工程学院 一种利用枯草芽孢杆菌生产红色素的方法
CN106434801B (zh) * 2016-08-29 2020-09-11 湖北大学 一种芽胞杆菌高产普切明的发酵工艺
CN108570477B (zh) * 2018-04-18 2020-06-30 横琴仲泰生物医药有限公司 一种碱性蛋白酶基因及其重组枯草芽孢杆菌菌株的构建方法
EP4031560A1 (en) 2019-08-14 2022-07-27 Danisco US Inc Compositions and methods for increased protein production in bacillus licheniformis
CN116669573A (zh) * 2020-07-19 2023-08-29 以色列国家农业部·农村发展农业研究组织·沃尔卡尼机构 培养益生菌的方法
WO2022178432A1 (en) 2021-02-22 2022-08-25 Danisco Us Inc. Methods and compositions for producing proteins of interest in pigment deficient bacillus cells
BR112023027009A2 (pt) 2021-06-24 2024-03-12 Basf Se Célula hospedeira modificada de bacillus licheniformis, e, métodos para produzir um composto de interesse e para aumentar a pureza de um composto de interesse

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733753A (en) * 1992-12-22 1998-03-31 Novo Nordisk A/S Amplification of genomic DNA by site specific integration of a selectable marker construct
US5958728A (en) * 1996-11-18 1999-09-28 Novo Nordiskbiotech, Inc. Methods for producing polypeptides in mutants of bacillus cells
US5891701A (en) * 1997-06-12 1999-04-06 Novo Nordisk Biotech Inc. Nucleic acids encoding a polypeptide having protease activity
WO2003054163A2 (en) * 2001-12-21 2003-07-03 Novozymes Biopolymer A/S Methods for producing hyaluronan in a recombinant host cell
EP2021357B1 (en) 2006-04-26 2011-06-08 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Cyclodipeptide synthetases and their use for synthesis of cyclo(leu-leu) cyclodipeptide

Also Published As

Publication number Publication date
AU2003254196A8 (en) 2004-02-16
US20100330618A1 (en) 2010-12-30
US20040096944A1 (en) 2004-05-20
AU2003254196A1 (en) 2004-02-16
WO2004011609A2 (en) 2004-02-05
WO2004011609A3 (en) 2004-06-17
EP1537229A4 (en) 2011-01-12
CN1685057A (zh) 2005-10-19
US8124376B2 (en) 2012-02-28
US7476516B2 (en) 2009-01-13
US20090098606A1 (en) 2009-04-16
EP1537229A2 (en) 2005-06-08
CN100567501C (zh) 2009-12-09
US7666625B2 (en) 2010-02-23
EP1537229B1 (en) 2013-09-11

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