DE60334533D1 - Gewebe-engineering - Google Patents

Gewebe-engineering

Info

Publication number
DE60334533D1
DE60334533D1 DE60334533T DE60334533T DE60334533D1 DE 60334533 D1 DE60334533 D1 DE 60334533D1 DE 60334533 T DE60334533 T DE 60334533T DE 60334533 T DE60334533 T DE 60334533T DE 60334533 D1 DE60334533 D1 DE 60334533D1
Authority
DE
Germany
Prior art keywords
tissue engineering
engineering
lifespan
extending
general
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60334533T
Other languages
English (en)
Inventor
Laura E Niklason
Andrew J Mckee
Christopher M Counter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duke University
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Application granted granted Critical
Publication of DE60334533D1 publication Critical patent/DE60334533D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1276—RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • C12N5/0691—Vascular smooth muscle cells; 3D culture thereof, e.g. models of blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60334533T 2002-03-15 2003-03-17 Gewebe-engineering Expired - Lifetime DE60334533D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36408702P 2002-03-15 2002-03-15
PCT/US2003/008054 WO2003078597A2 (en) 2002-03-15 2003-03-17 Tissue engineering

Publications (1)

Publication Number Publication Date
DE60334533D1 true DE60334533D1 (de) 2010-11-25

Family

ID=28041870

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60334533T Expired - Lifetime DE60334533D1 (de) 2002-03-15 2003-03-17 Gewebe-engineering

Country Status (8)

Country Link
US (1) US7943378B2 (de)
EP (1) EP1487274B1 (de)
AT (1) ATE484195T1 (de)
AU (1) AU2003233404A1 (de)
CA (1) CA2479512C (de)
DE (1) DE60334533D1 (de)
ES (1) ES2353665T3 (de)
WO (1) WO2003078597A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002014480A2 (en) * 2000-08-16 2002-02-21 Duke University Decellularized tissue engineered constructs and tissues
CA2576055A1 (en) * 2004-08-05 2006-03-23 Steven E. Artandi Methods and compositions for cell activation
EP1693025A1 (de) 2005-02-17 2006-08-23 Universität Zürich Verfahren zur Herstellung einer Prothese aus Gewebe
US20130013083A1 (en) * 2011-01-06 2013-01-10 Humacyte Tissue-Engineered Constructs
JP5878181B2 (ja) 2011-01-06 2016-03-08 ヒューマサイト 組織工学構築物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6172210B1 (en) * 1996-04-02 2001-01-09 Blood Center Research Foundation DNA encoding phospholipid scramblase
US6331406B1 (en) * 1997-03-31 2001-12-18 The John Hopkins University School Of Medicine Human enbryonic germ cell and methods of use
EP0893493A3 (de) * 1997-07-21 2002-12-04 Aventis Pharma Deutschland GmbH Genetisch veränderte Zellen und deren Verwendung in der Prophylaxe oder Therapie von Erkrankungen
WO1999035245A2 (en) * 1998-01-12 1999-07-15 Board Of Regents, The University Of Texas System Methods for preparing and using immortalized human neuroendocrine cells
US6399384B1 (en) * 1999-09-17 2002-06-04 Reneuron Limited Conditional immortalization of cells
AU2002232405A1 (en) * 2000-11-20 2002-05-27 California Institute Of Technology Artery smooth muscle- and vein smooth muscle-specific proteins and uses therefor
US20040044403A1 (en) * 2001-10-30 2004-03-04 Joyce Bischoff Tissue-engineered vascular structures
US7166464B2 (en) * 2001-12-11 2007-01-23 Cytograft Tissue Engineering, Inc. Method of culturing cells to produce a tissue sheet
US20030175961A1 (en) * 2002-02-26 2003-09-18 Herron G. Scott Immortal micorvascular endothelial cells and uses thereof

Also Published As

Publication number Publication date
EP1487274A4 (de) 2006-06-21
EP1487274B1 (de) 2010-10-13
ATE484195T1 (de) 2010-10-15
AU2003233404A1 (en) 2003-09-29
ES2353665T3 (es) 2011-03-03
WO2003078597A9 (en) 2003-12-11
CA2479512C (en) 2012-10-16
EP1487274A2 (de) 2004-12-22
US7943378B2 (en) 2011-05-17
WO2003078597A3 (en) 2004-04-08
US20030235562A1 (en) 2003-12-25
AU2003233404A8 (en) 2003-09-29
WO2003078597A2 (en) 2003-09-25
CA2479512A1 (en) 2003-09-25

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