ATE511753T1 - Postnatale stammzellen und deren verwendungen - Google Patents

Postnatale stammzellen und deren verwendungen

Info

Publication number
ATE511753T1
ATE511753T1 AT03724136T AT03724136T ATE511753T1 AT E511753 T1 ATE511753 T1 AT E511753T1 AT 03724136 T AT03724136 T AT 03724136T AT 03724136 T AT03724136 T AT 03724136T AT E511753 T1 ATE511753 T1 AT E511753T1
Authority
AT
Austria
Prior art keywords
cells
stem cells
postnatal
relates
postnatal stem
Prior art date
Application number
AT03724136T
Other languages
English (en)
Inventor
Songtao Shi
Pamela Robey
Masako Miura
Stan Gronthos
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of ATE511753T1 publication Critical patent/ATE511753T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0664—Dental pulp stem cells, Dental follicle stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
    • C12N2506/1361—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from dental pulp or dental follicle stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin
AT03724136T 2003-04-19 2003-04-19 Postnatale stammzellen und deren verwendungen ATE511753T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2003/012276 WO2004094588A2 (en) 2003-04-19 2003-04-19 Postnatal stem cells and uses thereof

Publications (1)

Publication Number Publication Date
ATE511753T1 true ATE511753T1 (de) 2011-06-15

Family

ID=33308987

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03724136T ATE511753T1 (de) 2003-04-19 2003-04-19 Postnatale stammzellen und deren verwendungen

Country Status (7)

Country Link
US (3) US9175264B2 (de)
EP (1) EP1619949B1 (de)
AT (1) ATE511753T1 (de)
AU (1) AU2003231015B2 (de)
CA (1) CA2522669C (de)
ES (1) ES2366085T3 (de)
WO (1) WO2004094588A2 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8062675B2 (en) * 1999-07-07 2011-11-22 Angioblast Systems, Inc. Mesenchymal precursor cell
US7670628B2 (en) * 1999-07-07 2010-03-02 Angioblast Systems, Inc. Mesenchymal precursor cell
US20050158289A1 (en) * 1999-07-07 2005-07-21 Simmons Paul J. Mesenchymal precursor cell and use thereof in the repair of bone defects and fractures in mammals
AUPQ147799A0 (en) * 1999-07-07 1999-07-29 Medvet Science Pty. Ltd. Mesenchymal precursor cell
AU2003901668A0 (en) 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
EP1619949B1 (de) 2003-04-19 2011-06-08 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Postnatale stammzellen und deren verwendungen
ITNA20040043A1 (it) * 2004-07-28 2004-10-28 Francesco Carinci Tecnica di ingegneria tissutale ottenibile mediante isolamento di una nuova sottopopolazione di cellule staminali mbp-shed ed mbp-dpsc, isolate da polpa di denti decidui e permanenti in grado di produrre in vitro tessuto osseo umano.
KR20070085288A (ko) * 2004-09-24 2007-08-27 안지오블라스트 시스템스 인코퍼레이티드 간엽 전구세포의 증식 및/또는 생존성 증강 방법
US20070258957A1 (en) * 2006-05-04 2007-11-08 Russell Bowermaster Method for obtaining and storing multipotent stem cells
DE602005012081D1 (de) * 2005-07-29 2009-02-12 Univ Bonn Verfahren zur Isolierung von Stammzellen aus ein kissenformiges Gewebe der Zähne
WO2008080200A1 (en) * 2006-12-29 2008-07-10 Irina Kerkis Process for obtaining stem cells
WO2009044943A1 (en) * 2007-10-01 2009-04-09 Seoul National University Industry Foundation Various human dental stem cells having a mineralization ability and the method for culturing them
JP5408578B2 (ja) * 2007-12-05 2014-02-05 国立大学法人名古屋大学 歯髄幹細胞を用いた自家又は同種移植用組成物及びその用途
WO2009113733A1 (ja) * 2008-03-12 2009-09-17 財団法人ヒューマンサイエンス振興財団 根管充填材及び歯組織再生方法
WO2009124213A2 (en) * 2008-04-02 2009-10-08 The Trustees Of Columbia University In The City Of New York Dental stem cell differentiation
ITRM20080342A1 (it) 2008-06-26 2009-12-27 Univ Degli Studi Udine Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.
US20110177041A1 (en) * 2008-08-22 2011-07-21 Misako Nakashima Material for treatment of cerebral infarction and brain tissue regeneration method
US10328103B2 (en) 2009-01-03 2019-06-25 Ray C. Wasielewski Medical treatment composition comprising mammalian dental pulp stem cells
US20100172951A1 (en) 2009-01-03 2010-07-08 Ray Wasielewski Enhanced Medical Implant
US8470308B2 (en) * 2009-01-03 2013-06-25 Ray C. Wasielewski Enhanced medical implant comprising disrupted tooth pulp and tooth particles
WO2010083730A1 (zh) * 2009-01-23 2010-07-29 赛尔珍尼克斯生物科学公司 牙齿相关干细胞的新用途
US20150335400A1 (en) * 2009-06-17 2015-11-26 The Trustees Of Columbia University In The City Of New York Tooth scaffolds
US20130022989A1 (en) * 2009-06-25 2013-01-24 The Trustees Of Columbia University In The City Of New York Dental stem cell reprogramming
CN102596270B (zh) 2009-09-11 2016-10-12 独立行政法人国立长寿医疗研究中心 非拔牙根管填充材料以及非拔牙的牙组织再生方法
WO2011118795A1 (ja) * 2010-03-26 2011-09-29 国立大学法人名古屋大学 損傷部治療用組成物
WO2012048275A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
WO2013011131A2 (en) * 2011-07-20 2013-01-24 Angewandte Biotechnologie Gmbh Pluripotent tendon and ligament perivascular cells
CA2846318C (en) * 2013-03-15 2020-04-28 Ray C. Wasielewski Enhanced medical implant
US10633625B2 (en) 2013-11-16 2020-04-28 Terumo Bct, Inc. Expanding cells in a bioreactor
WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
CN106715676A (zh) 2014-09-26 2017-05-24 泰尔茂比司特公司 按计划供养
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
CN110612344B (zh) 2017-03-31 2023-09-12 泰尔茂比司特公司 细胞扩增
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
EP3817753A1 (de) * 2018-07-03 2021-05-12 Universidad del País Vasco - Euskal Herriko Unibertsitatea Zellaggregate zur verwendung in der vaskularisierungstherapie
CN109321522A (zh) * 2018-11-20 2019-02-12 潍坊市康华生物技术有限公司 一种制备牙髓干细胞的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7707801A (en) * 2000-07-21 2002-02-05 Us Health Adult human dental pulp stem cells in vitro and in vivo
DE60321440D1 (de) 2002-02-06 2008-07-17 Stiftung Caesar Aus zähnen gewonnene pluripotente embryonalähnliche stammzellen und verwendungen davon
EP1619949B1 (de) 2003-04-19 2011-06-08 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Postnatale stammzellen und deren verwendungen

Also Published As

Publication number Publication date
US20160008404A1 (en) 2016-01-14
EP1619949A2 (de) 2006-02-01
US20070274958A1 (en) 2007-11-29
EP1619949A4 (de) 2007-07-04
ES2366085T3 (es) 2011-10-17
AU2003231015A1 (en) 2004-11-19
CA2522669C (en) 2013-06-18
US9175264B2 (en) 2015-11-03
US20170258847A1 (en) 2017-09-14
CA2522669A1 (en) 2004-11-04
AU2003231015B2 (en) 2009-10-08
US9682107B2 (en) 2017-06-20
WO2004094588A3 (en) 2004-12-16
WO2004094588A2 (en) 2004-11-04
EP1619949B1 (de) 2011-06-08

Similar Documents

Publication Publication Date Title
ATE511753T1 (de) Postnatale stammzellen und deren verwendungen
IL273422A (en) Methods and systems for extracorporeal organ treatment
TW200618817A (en) Diffractive colorants for cosmetics
ATE437663T1 (de) Legierungszusammensetzungen und diese enthaltende vorrichtungen
HK1085140A1 (en) Pharmaceutical compositions and method of using levodopa and carbidopa
TW200612918A (en) Lonidamine analogs
UA94221C2 (en) Lipocalin protein
SG155947A1 (en) Compositions and methods for the diagnosis and treatment of tumor
DE602005027899D1 (de) Mundpflegezusammensetzung mit dem extrakt von unoxidierter kamelie
ATE397654T1 (de) Aus zähnen gewonnene pluripotente embryonalähnliche stammzellen und verwendungen davon
MX2010003258A (es) Utilizacion de un nuevo agente natural en composiciones cosmeticas.
ITRM20030210A1 (it) Protesi da impiegarsi nella terapia chirurgica del prolasso
MX2009006452A (es) Gel-crema que comprende al menos un retinoide y peroxido de benzoilo.
TW200716091A (en) New therapeutic combinations for the treatment or prevention of psychotic disorders
MY155032A (en) High fluoride ion oral care composition and method for maintaining anticaries activity
NO20055741D0 (no) Nye kjemiske forbindelser
PL1654253T3 (pl) Podstawione pochodne 3-pirolidynoindolu
WO2004000293A3 (fr) Utilisation de la taurine ou de derives pour le traitement de l'alopecie
ATE431846T1 (de) Neurale stammzellen
ATE322901T1 (de) Maca und geweih zur steigerung des testosteronspiegels
WO2005052140A3 (en) Multipotent postnatal stem cells from human periodontal ligament and uses thereof
IL175303A0 (en) Oral formulations for 5-ht-receptor agonists, uses and methods of treatment employing the same
MX2007002277A (es) Metodos para formar retinoides y usos de los mismos.
IL174594A (en) MANIPULATED NKT CELLS MODULATING THE Th1/Th2 BALANCE, USES AND THERAPEUTIC COMPOSITIONS THEREOF IN THE TREATMENT OF IMMUNE-RELATED DISORDERS
SG165324A1 (en) Compositions and methods to counteract oral malodour

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties