BR0114561A - Derivados amida reticulados do acido hialurÈnico e método de produção dos mesmos - Google Patents
Derivados amida reticulados do acido hialurÈnico e método de produção dos mesmosInfo
- Publication number
- BR0114561A BR0114561A BR0114561-4A BR0114561A BR0114561A BR 0114561 A BR0114561 A BR 0114561A BR 0114561 A BR0114561 A BR 0114561A BR 0114561 A BR0114561 A BR 0114561A
- Authority
- BR
- Brazil
- Prior art keywords
- hyaluronic acid
- amide derivatives
- cross
- production
- linked
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
Abstract
"DERIVADOS AMIDA RETICULADOS DO áCIDO HIALURÈNICO E MéTODO DE PRODUçãO DOS MESMOS". A presente invenção refere-se a derivados amida reticulados, insolúveis em água de ácido hialurónico e métodos de produção destes, onde os derivados amida do ácido hialurónico são caracterizados por reticulação do polímero ou oligómero com dois ou mais grupos amina, com ácido hialurónico ou seus sais de hialuronato, através de reação de amidação. Os derivados amida reticulados, insolúveis em água de ácido hialurónico de acordo com a presente invenção podem ser usados diferentemente, para prevenção de aderência apos operação cirúrgica, correção de rugas faciais, crescimento dérmico, engenharia de tecido, visco-suplemento para osteoartrite, etc.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2000-0059443A KR100375299B1 (ko) | 2000-10-10 | 2000-10-10 | 히알루론산의 가교결합형 아마이드 유도체와 이의 제조방법 |
PCT/KR2001/001687 WO2002030990A1 (en) | 2000-10-10 | 2001-10-10 | Crosslinked amide derivatives of hyaluronic acid and manufacturing method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0114561A true BR0114561A (pt) | 2003-08-26 |
Family
ID=19692693
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0114561-4A BR0114561A (pt) | 2000-10-10 | 2001-10-10 | Derivados amida reticulados do acido hialurÈnico e método de produção dos mesmos |
Country Status (8)
Country | Link |
---|---|
US (1) | US6903199B2 (pt) |
EP (1) | EP1328552B1 (pt) |
JP (1) | JP4230767B2 (pt) |
KR (1) | KR100375299B1 (pt) |
CN (1) | CN1290869C (pt) |
AU (1) | AU2001294320A1 (pt) |
BR (1) | BR0114561A (pt) |
WO (1) | WO2002030990A1 (pt) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITPD980169A1 (it) | 1998-07-06 | 2000-01-06 | Fidia Advanced Biopolymers Srl | Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione. |
KR20040009891A (ko) * | 2002-07-26 | 2004-01-31 | 주식회사 엘지생명과학 | 히알루론산의 유도체 겔 및 그 제조방법 |
KR100523953B1 (ko) * | 2002-08-27 | 2005-10-25 | 주식회사 엘지생명과학 | 천연다당류와 히알루론산의 마이크로비드 및 이의 제조 방법 |
KR100507545B1 (ko) * | 2002-09-03 | 2005-08-09 | 주식회사 엘지생명과학 | 히알루론산 유도체 및 그의 제조방법 |
FR2861734B1 (fr) | 2003-04-10 | 2006-04-14 | Corneal Ind | Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus |
US20050220721A1 (en) * | 2004-03-17 | 2005-10-06 | Kablik J J | Anti-adhesion spraying |
ES2246695B1 (es) | 2004-04-29 | 2007-05-01 | Instituto Cientifico Y Tecnologico De Navarra, S.A. | Composicion estimuladora de la respuesta inmunitaria que comprende nanoparticulas a base de un copolimero de metil vinil eter y anhidrido maleico. |
ES2246694B1 (es) | 2004-04-29 | 2007-05-01 | Instituto Cientifico Y Tecnologico De Navarra, S.A. | Nanoparticulas pegiladas. |
ITPD20050056A1 (it) * | 2005-03-02 | 2006-09-03 | Fidia Farmaceutici | Derivati ammidici del'acido ialuronico in osteoartrosi |
KR100737954B1 (ko) * | 2006-01-03 | 2007-07-13 | 고려대학교 산학협력단 | 조직재생을 위한 히알루론산-기초된 주사형 하이드로겔 |
US7674781B2 (en) * | 2006-04-28 | 2010-03-09 | Heather Sheardown | Hyaluronic acid-retaining polymers |
CA2657823A1 (en) * | 2006-08-04 | 2008-02-07 | Novozymes Biopolymer A/S | Branched hyaluronic acid and method of manufacture |
US8043773B2 (en) | 2006-11-16 | 2011-10-25 | Ricoh Company, Limited | Image bearing member, image forming apparatus and process cartridge |
JP5006164B2 (ja) | 2006-11-21 | 2012-08-22 | 株式会社リコー | 画像形成装置、画像形成方法及びプロセスカートリッジ |
BRPI0811784A2 (pt) * | 2007-05-23 | 2011-05-10 | Allergan Inc | colÁgeno reticulado e uso do mesmo |
JP5382404B2 (ja) | 2007-07-02 | 2014-01-08 | 株式会社リコー | 電子写真感光体、該電子写真感光体を有するプロセスカートリッジ及び電子写真装置 |
US20110077737A1 (en) * | 2007-07-30 | 2011-03-31 | Allergan, Inc. | Tunably Crosslinked Polysaccharide Compositions |
US8697044B2 (en) | 2007-10-09 | 2014-04-15 | Allergan, Inc. | Crossed-linked hyaluronic acid and collagen and uses thereof |
EP2207424B1 (en) | 2007-11-16 | 2014-06-04 | Allergan, Inc. | Compositions and methods for treating purpura |
US8394784B2 (en) | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having multi-stage bioactive agent delivery |
US8394782B2 (en) | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having increased longevity |
KR101008595B1 (ko) * | 2008-05-16 | 2011-01-17 | 고형배 | 스크린 골프 연습 시스템 |
WO2009148985A2 (en) * | 2008-06-03 | 2009-12-10 | E. I. Du Pont De Nemours And Company | A tissue coating for preventing undesired tissue-to-tissue adhesions |
US8357795B2 (en) | 2008-08-04 | 2013-01-22 | Allergan, Inc. | Hyaluronic acid-based gels including lidocaine |
ES2829971T3 (es) | 2008-09-02 | 2021-06-02 | Tautona Group Lp | Hilos de ácido hialurónico y/o derivados de los mismos, métodos para fabricar los mismos y usos de los mismos |
CN102271658B (zh) | 2009-01-13 | 2013-06-12 | 佩加马公司 | 用于治疗伤口、瘢痕、外科手术后粘连形成的含有透明质酸的组合物 |
ES2621380T3 (es) * | 2009-04-02 | 2017-07-03 | Allergan, Inc. | Hidrogeles con forma de cabello para aumento de tejidos blandos |
KR101047510B1 (ko) * | 2009-04-07 | 2011-07-08 | (주)다림티센 | 에스터화 아텔로콜라겐과 히알루론산을 이용한 유착 방지제 제조방법 |
US9114188B2 (en) | 2010-01-13 | 2015-08-25 | Allergan, Industrie, S.A.S. | Stable hydrogel compositions including additives |
US20110172180A1 (en) | 2010-01-13 | 2011-07-14 | Allergan Industrie. Sas | Heat stable hyaluronic acid compositions for dermatological use |
EP2544652A2 (en) | 2010-03-12 | 2013-01-16 | Allergan Industrie SAS | A fluid composition comprising a hyaluronan polymer and mannitol for improving skin condition. |
DK2550027T4 (da) | 2010-03-22 | 2019-05-13 | Allergan Inc | Tværbundne polysaccharid- og protein-polysaccharid-hydrogeler til blødvævsforøgelse |
US8883139B2 (en) | 2010-08-19 | 2014-11-11 | Allergan Inc. | Compositions and soft tissue replacement methods |
US8889123B2 (en) | 2010-08-19 | 2014-11-18 | Allergan, Inc. | Compositions and soft tissue replacement methods |
US9005605B2 (en) | 2010-08-19 | 2015-04-14 | Allergan, Inc. | Compositions and soft tissue replacement methods |
US8697057B2 (en) | 2010-08-19 | 2014-04-15 | Allergan, Inc. | Compositions and soft tissue replacement methods |
KR101047512B1 (ko) * | 2011-04-20 | 2011-07-08 | (주)다림티센 | 에스터화 아텔로콜라겐과 히알루론산을 이용한 유착 방지제 제조방법 |
US20130096081A1 (en) | 2011-06-03 | 2013-04-18 | Allergan, Inc. | Dermal filler compositions |
EP2714002B1 (en) | 2011-06-03 | 2019-04-03 | Allergan, Inc. | Dermal filler compositions including antioxidants |
US9408797B2 (en) | 2011-06-03 | 2016-08-09 | Allergan, Inc. | Dermal filler compositions for fine line treatment |
US9393263B2 (en) | 2011-06-03 | 2016-07-19 | Allergan, Inc. | Dermal filler compositions including antioxidants |
US9662422B2 (en) | 2011-09-06 | 2017-05-30 | Allergan, Inc. | Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation |
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US9480747B2 (en) | 2012-01-24 | 2016-11-01 | Bvw Holding Ag | Class of anti-adhesion hydrogels with healing aspects |
CN102793952B (zh) * | 2012-08-20 | 2013-11-13 | 山东省立医院 | 防止肠粘连的凝胶材料 |
WO2014032780A1 (en) * | 2012-08-28 | 2014-03-06 | University Of Geneva | Hybrid hydrogels |
FR2997014B1 (fr) | 2012-10-24 | 2015-03-20 | Teoxane | Composition sterile dermo-injectable |
US20140315828A1 (en) | 2013-04-22 | 2014-10-23 | Allergan, Inc. | Cross-linked silk-hyaluronic acid compositions |
CN104208010A (zh) * | 2014-08-18 | 2014-12-17 | 广州贝奥吉因生物科技有限公司 | 一种纳米靶向缓控释系统的制备方法 |
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EP3200838B1 (en) | 2014-09-30 | 2019-09-18 | Allergan Industrie, SAS | Stable hydrogel compositions including additives |
WO2016128783A1 (en) | 2015-02-09 | 2016-08-18 | Allergan Industrie Sas | Compositions and methods for improving skin appearance |
CN105381501A (zh) * | 2015-12-15 | 2016-03-09 | 日照天一生物医疗科技有限公司 | 可降解生物复合止血膜及其制备方法 |
EP3623390B1 (en) | 2015-12-29 | 2023-08-02 | Galderma S.A. | Carbohydrate crosslinker |
EP3252082A1 (en) * | 2016-05-31 | 2017-12-06 | Galderma S.A. | Method for deacetylation of biopolymers |
US10668190B2 (en) | 2016-05-03 | 2020-06-02 | Bvw Holding Ag | Multiphase gel |
PT3623390T (pt) | 2016-05-31 | 2023-10-27 | Galderma Sa | Reticulador de hidrato de carbono |
CN106693067A (zh) * | 2016-07-15 | 2017-05-24 | 温州生物材料与工程研究所 | 一种自愈合无模板多孔支架的制备 |
CA3033536A1 (en) | 2016-08-24 | 2018-03-01 | Allergan, Inc. | Co-crosslinked hyaluronic acid-silk fibroin hydrogels for improving tissue graft viability and for soft tissue augmentation |
KR101969446B1 (ko) * | 2017-06-30 | 2019-04-16 | 한양대학교 산학협력단 | 히알루론산 기반 보습 소재 |
CN109602686A (zh) * | 2019-02-02 | 2019-04-12 | 西安力邦制药有限公司 | 一种水凝胶化妆品组合物及其制备方法 |
CN109939260A (zh) * | 2019-03-01 | 2019-06-28 | 昆明理工大学 | 一种医用壳聚糖/透明质酸钠偶联水凝胶的制备方法 |
CN110773241A (zh) * | 2019-09-16 | 2020-02-11 | 浙江工业大学 | 一种耐有机溶剂阳离子交换膜的制备方法 |
CN110773240A (zh) * | 2019-09-16 | 2020-02-11 | 浙江工业大学 | 一种兼具耐高温及耐有机溶剂阳离子交换膜的制备方法 |
KR20220110786A (ko) | 2019-12-02 | 2022-08-09 | 갈더마 홀딩 소시에떼 아노님 | 고분자량 에스테틱 조성물 |
CN111249519A (zh) * | 2020-01-17 | 2020-06-09 | 浙江理工大学 | 一种皮肤创口粘合修复材料及其制备方法、应用 |
CN111732675A (zh) * | 2020-08-18 | 2020-10-02 | 山东华熙海御生物医药有限公司 | 透明质酸-氨基葡萄糖接枝共聚物、制法及其应用 |
CN114716581A (zh) * | 2022-03-25 | 2022-07-08 | 常州百瑞吉生物医药有限公司 | 一种多重改性透明质酸衍生物及其应用 |
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SE456346B (sv) | 1984-07-23 | 1988-09-26 | Pharmacia Ab | Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning |
US4582865A (en) | 1984-12-06 | 1986-04-15 | Biomatrix, Inc. | Cross-linked gels of hyaluronic acid and products containing such gels |
US4713448A (en) | 1985-03-12 | 1987-12-15 | Biomatrix, Inc. | Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues |
US5017229A (en) | 1990-06-25 | 1991-05-21 | Genzyme Corporation | Water insoluble derivatives of hyaluronic acid |
US6174999B1 (en) * | 1987-09-18 | 2001-01-16 | Genzyme Corporation | Water insoluble derivatives of polyanionic polysaccharides |
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JPH0675680B2 (ja) * | 1988-08-09 | 1994-09-28 | 富士紡績株式会社 | 陰イオン交換能を有するキトサン成形物の製造法 |
US5708152A (en) * | 1992-03-27 | 1998-01-13 | Ciba Specialty Chemicals Corporation | N-substituted chitosan derivatives in a process for their preparation |
US5616568A (en) * | 1993-11-30 | 1997-04-01 | The Research Foundation Of State University Of New York | Functionalized derivatives of hyaluronic acid |
US5597811A (en) * | 1995-04-10 | 1997-01-28 | Amerchol Corporation | Oxirane carboxylic acid derivatives of polyglucosamines |
KR19990049107A (ko) * | 1997-12-11 | 1999-07-05 | 이영무 | 고분자 전해질 복합체 스폰지의 제조방법 |
ITPD980169A1 (it) * | 1998-07-06 | 2000-01-06 | Fidia Advanced Biopolymers Srl | Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione. |
IT1303738B1 (it) * | 1998-11-11 | 2001-02-23 | Aquisitio S P A | Processo di reticolazione di polisaccaridi carbossilati. |
IT1303735B1 (it) * | 1998-11-11 | 2001-02-23 | Falorni Italia Farmaceutici S | Acidi ialuronici reticolati e loro usi medici. |
JP4187917B2 (ja) * | 2000-09-08 | 2008-11-26 | 独立行政法人科学技術振興機構 | 組織再生マトリックス用グリコサミノグリカン−コラーゲン複合体の製造方法 |
-
2000
- 2000-10-10 KR KR10-2000-0059443A patent/KR100375299B1/ko not_active IP Right Cessation
-
2001
- 2001-10-10 AU AU2001294320A patent/AU2001294320A1/en not_active Abandoned
- 2001-10-10 BR BR0114561-4A patent/BR0114561A/pt not_active IP Right Cessation
- 2001-10-10 CN CNB018170986A patent/CN1290869C/zh not_active Expired - Fee Related
- 2001-10-10 WO PCT/KR2001/001687 patent/WO2002030990A1/en active Application Filing
- 2001-10-10 US US10/398,065 patent/US6903199B2/en not_active Expired - Fee Related
- 2001-10-10 JP JP2002534373A patent/JP4230767B2/ja not_active Expired - Fee Related
- 2001-10-10 EP EP01974948A patent/EP1328552B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO2002030990A1 (en) | 2002-04-18 |
KR20020028435A (ko) | 2002-04-17 |
CN1468262A (zh) | 2004-01-14 |
US6903199B2 (en) | 2005-06-07 |
US20040014960A1 (en) | 2004-01-22 |
EP1328552B1 (en) | 2012-12-12 |
JP2004511588A (ja) | 2004-04-15 |
KR100375299B1 (ko) | 2003-03-10 |
EP1328552A4 (en) | 2005-11-09 |
JP4230767B2 (ja) | 2009-02-25 |
CN1290869C (zh) | 2006-12-20 |
EP1328552A1 (en) | 2003-07-23 |
AU2001294320A1 (en) | 2002-04-22 |
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