BR0014489B1 - processo de produÇço de adenovÍrus, e, kit. - Google Patents
processo de produÇço de adenovÍrus, e, kit.Info
- Publication number
- BR0014489B1 BR0014489B1 BRPI0014489-4A BR0014489A BR0014489B1 BR 0014489 B1 BR0014489 B1 BR 0014489B1 BR 0014489 A BR0014489 A BR 0014489A BR 0014489 B1 BR0014489 B1 BR 0014489B1
- Authority
- BR
- Brazil
- Prior art keywords
- kit
- production process
- adenoviruses
- adenovirus production
- banks
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/861—Adenoviral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10351—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9912521A FR2799472B1 (fr) | 1999-10-07 | 1999-10-07 | Preparation d'adenovirus recombinants et de banques adenovirales |
US16835699P | 1999-12-01 | 1999-12-01 | |
PCT/FR2000/002774 WO2001025463A1 (fr) | 1999-10-07 | 2000-10-05 | Preparation d'adenovirus recombinants et de banques adenovirales |
Publications (2)
Publication Number | Publication Date |
---|---|
BR0014489A BR0014489A (pt) | 2002-06-04 |
BR0014489B1 true BR0014489B1 (pt) | 2013-05-21 |
Family
ID=26235132
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0014489-4A BR0014489B1 (pt) | 1999-10-07 | 2000-10-05 | processo de produÇço de adenovÍrus, e, kit. |
Country Status (22)
Country | Link |
---|---|
US (1) | US8263395B2 (pt) |
EP (1) | EP1224310B1 (pt) |
JP (1) | JP5260815B2 (pt) |
KR (1) | KR100928105B1 (pt) |
CN (1) | CN1384885B (pt) |
AT (1) | ATE355385T1 (pt) |
AU (1) | AU785431B2 (pt) |
BR (1) | BR0014489B1 (pt) |
CA (1) | CA2383225C (pt) |
CZ (1) | CZ302282B6 (pt) |
DE (1) | DE60033679T2 (pt) |
DK (1) | DK1224310T3 (pt) |
FR (1) | FR2799472B1 (pt) |
HK (1) | HK1050211B (pt) |
HU (1) | HU228933B1 (pt) |
IL (2) | IL148493A0 (pt) |
MX (1) | MXPA02003247A (pt) |
NO (1) | NO330916B1 (pt) |
NZ (1) | NZ518763A (pt) |
PL (1) | PL210590B1 (pt) |
WO (1) | WO2001025463A1 (pt) |
ZA (1) | ZA200202481B (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001234980A1 (en) * | 2000-02-09 | 2001-08-20 | Genvec, Inc. | Methods of preparing and using a viral vector library |
EP2471909A1 (en) * | 2010-12-30 | 2012-07-04 | SIRION BIOTECH GmbH | Nucleic acid molecules for generating adenoviral vectors |
GB201322851D0 (en) * | 2013-12-23 | 2014-02-12 | Psioxus Therapeutics Ltd | Method |
CN109576231B (zh) * | 2017-09-28 | 2022-03-25 | 北京康万达医药科技有限公司 | 分离的重组溶瘤腺病毒、药物组合物及其在治疗肿瘤和/或癌症的药物中的用途 |
JP7287611B2 (ja) * | 2018-02-07 | 2023-06-06 | 学校法人日本医科大学 | 改良型アデノ随伴ウイルスベクター |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3486053T3 (de) | 1983-10-20 | 2004-01-08 | The Research Foundation Of State University Of New York | Regulierung von Gen-Expression durch Translationshemmung unter Verwendung von m-RNS hinderndem Komplementär-RNS. |
FR2573436B1 (fr) | 1984-11-20 | 1989-02-17 | Pasteur Institut | Adn recombinant comportant une sequence nucleotidique codant pour un polypeptide determine sous le controle d'un promoteur d'adenovirus, vecteurs contenant cet adn recombinant, cellules eucaryotes transformees par cet adn recombinant, produits d'excretion de ces cellules transformees et leurs applications, notamment a la constitution de vaccins |
US6696420B1 (en) * | 1984-11-20 | 2004-02-24 | Institut Pasteur | Adenoviral vector with a deletion in the E1A coding region expressing a hetorologous protein |
US6007806A (en) * | 1986-08-13 | 1999-12-28 | Transgene S.A. | Expression of a tumor-specific antigen by a recombinant vector virus and use thereof in preventive or curative treatment of the corresponding tumor |
FR2602790B1 (fr) | 1986-08-13 | 1990-06-01 | Transgene Sa | Expression d'un antigene specifique de tumeur par un virus vecteur recombinant et utilisation de celui-ci pour le traitement preventif ou curatif de la tumeur correspondante |
US5744133A (en) * | 1986-08-13 | 1998-04-28 | Transgene S.A. | Expression of a tumor-specific antigen by a recombinant vector virus and use thereof in preventitive or curative treatment of the corresponding tumor |
FR2688514A1 (fr) | 1992-03-16 | 1993-09-17 | Centre Nat Rech Scient | Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant. |
EP0673431A1 (en) | 1992-12-03 | 1995-09-27 | Genzyme Corporation | Gene therapy for cystic fibrosis |
FR2704556B1 (fr) | 1993-04-30 | 1995-07-13 | Rhone Poulenc Rorer Sa | Virus recombinants et leur utilisation en thérapie génique. |
FR2705363B1 (fr) | 1993-05-13 | 1995-08-11 | Clecim Sa | Procédé de fusion de ferraille dans un four électrique et installation pour la mise en Óoeuvre du procédé. |
FR2705361B1 (fr) | 1993-05-18 | 1995-08-04 | Centre Nat Rech Scient | Vecteurs viraux et utilisation en thérapie génique. |
FR2705686B1 (fr) * | 1993-05-28 | 1995-08-18 | Transgene Sa | Nouveaux adénovirus défectifs et lignées de complémentation correspondantes. |
US6133028A (en) * | 1993-05-28 | 2000-10-17 | Transgene S.A. | Defective adenoviruses and corresponding complementation lines |
CA2144040A1 (fr) | 1993-07-13 | 1995-01-26 | Michel Perricaudet | Vecteurs adenoviraux defectifs et utilisation en therapie genique |
FR2718150B1 (fr) * | 1994-03-29 | 1996-04-26 | Rhone Poulenc Rorer Sa | Virus recombinants, préparation et utilisation en thérapie génique. |
US7252989B1 (en) | 1994-04-04 | 2007-08-07 | Board Of Regents, The University Of Texas System | Adenovirus supervector system |
ATE336587T1 (de) | 1994-06-10 | 2006-09-15 | Genvec Inc | Adenoviren-vektor systeme und zelllinien |
FR2724945B1 (fr) * | 1994-09-27 | 1996-12-27 | Centre Nat Rech Scient | Vecteurs viraux et utilisation en therapie genique |
FR2726285B1 (fr) | 1994-10-28 | 1996-11-29 | Centre Nat Rech Scient | Adenovirus depourvus de particules contaminantes viables, preparation et utilisation |
FR2730504B1 (fr) * | 1995-02-13 | 1997-03-28 | Rhone Poulenc Rorer Sa | Procede de preparation de genomes d'adenovirus recombinants |
FR2730411B1 (fr) * | 1995-02-14 | 1997-03-28 | Centre Nat Rech Scient | Association medicamenteuse utile pour la transfection et l'expression in vivo d'exogenes |
AU724922B2 (en) * | 1995-06-07 | 2000-10-05 | Invitrogen Corporation | Recombinational cloning using engineered recombination sites |
US5783431A (en) * | 1996-04-24 | 1998-07-21 | Chromaxome Corporation | Methods for generating and screening novel metabolic pathways |
FR2749857B1 (fr) * | 1996-06-12 | 1998-08-14 | Centre Nat Rech Scient | Generation de molecules replicatives in vivo |
FR2755975B1 (fr) | 1996-11-15 | 1999-05-07 | Rhone Poulenc Rorer Sa | Virus recombinants bicistroniques utiles pour le traitement de pathologies liees aux dyslipoproteinemies |
US5846812A (en) * | 1996-11-22 | 1998-12-08 | Pioneer Hi-Bred International, Inc. | Zearalenone detoxification compositions and methods |
FR2774699B1 (fr) * | 1997-11-17 | 2003-10-03 | Rhone Poulenc Rorer Sa | Methode de reduction des evenements de recombinaison homologue |
US5922576A (en) * | 1998-02-27 | 1999-07-13 | The John Hopkins University | Simplified system for generating recombinant adenoviruses |
US6844270B2 (en) * | 2000-11-26 | 2005-01-18 | Shipley Company, L.L.C. | Polymers and photoresist compositions for short wavelength imaging |
SE523617C2 (sv) * | 2001-10-01 | 2004-05-04 | Sandvik Ab | Skär för spånavskiljande bearbetning försedd med spånbrytande geometri |
JP4308485B2 (ja) * | 2002-07-08 | 2009-08-05 | パナソニック株式会社 | 容量素子の製造方法 |
US6856551B2 (en) * | 2003-02-06 | 2005-02-15 | Sandisk Corporation | System and method for programming cells in non-volatile integrated memory devices |
-
1999
- 1999-10-07 FR FR9912521A patent/FR2799472B1/fr not_active Expired - Fee Related
-
2000
- 2000-10-05 AT AT00967960T patent/ATE355385T1/de not_active IP Right Cessation
- 2000-10-05 PL PL354099A patent/PL210590B1/pl unknown
- 2000-10-05 MX MXPA02003247A patent/MXPA02003247A/es active IP Right Grant
- 2000-10-05 DK DK00967960T patent/DK1224310T3/da active
- 2000-10-05 WO PCT/FR2000/002774 patent/WO2001025463A1/fr active IP Right Grant
- 2000-10-05 CA CA2383225A patent/CA2383225C/fr not_active Expired - Fee Related
- 2000-10-05 EP EP00967960A patent/EP1224310B1/fr not_active Expired - Lifetime
- 2000-10-05 JP JP2001528614A patent/JP5260815B2/ja not_active Expired - Fee Related
- 2000-10-05 DE DE60033679T patent/DE60033679T2/de not_active Expired - Lifetime
- 2000-10-05 CN CN008149038A patent/CN1384885B/zh not_active Expired - Fee Related
- 2000-10-05 CZ CZ20021215A patent/CZ302282B6/cs not_active IP Right Cessation
- 2000-10-05 KR KR1020027004452A patent/KR100928105B1/ko not_active IP Right Cessation
- 2000-10-05 NZ NZ518763A patent/NZ518763A/en not_active IP Right Cessation
- 2000-10-05 HU HU0203801A patent/HU228933B1/hu unknown
- 2000-10-05 AU AU77947/00A patent/AU785431B2/en not_active Ceased
- 2000-10-05 BR BRPI0014489-4A patent/BR0014489B1/pt not_active IP Right Cessation
- 2000-10-05 IL IL14849300A patent/IL148493A0/xx unknown
-
2002
- 2002-03-04 IL IL148493A patent/IL148493A/en not_active IP Right Cessation
- 2002-03-27 ZA ZA200202481A patent/ZA200202481B/xx unknown
- 2002-04-05 NO NO20021634A patent/NO330916B1/no not_active IP Right Cessation
-
2003
- 2003-01-24 HK HK03100648.3A patent/HK1050211B/zh not_active IP Right Cessation
-
2008
- 2008-12-08 US US12/329,772 patent/US8263395B2/en not_active Expired - Lifetime
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] |
Free format text: O DEPOSITANTE DEVERA APRESENTAR A PETICAO DEVIDA PARA O CUMPRIMENTO DESTA EXIGENCIA EM ATE 60 (SESSENTA) DIAS, CONTADOS A PARTIR DA DATA DE PUBLICACAO NA RPI, DE ACORDO COM O ART. 34 (II) DA LPI PARA QUE SE DE INICIO AO EXAME TECNICO DO PEDIDO. |
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B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 21/05/2013, OBSERVADAS AS CONDICOES LEGAIS. |
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B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 15A ANUIDADE. |
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B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2326 DE 04-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |