ZA200202481B - Recombinant adenoviruses preparation and adenovirus banks. - Google Patents

Recombinant adenoviruses preparation and adenovirus banks.

Info

Publication number
ZA200202481B
ZA200202481B ZA200202481A ZA200202481A ZA200202481B ZA 200202481 B ZA200202481 B ZA 200202481B ZA 200202481 A ZA200202481 A ZA 200202481A ZA 200202481 A ZA200202481 A ZA 200202481A ZA 200202481 B ZA200202481 B ZA 200202481B
Authority
ZA
South Africa
Prior art keywords
banks
adenovirus
preparation
recombinant adenoviruses
adenoviruses
Prior art date
Application number
ZA200202481A
Other languages
English (en)
Inventor
Jean-Jacques Robert
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of ZA200202481B publication Critical patent/ZA200202481B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • C12N15/861Adenoviral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/30Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron
ZA200202481A 1999-10-07 2002-03-27 Recombinant adenoviruses preparation and adenovirus banks. ZA200202481B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9912521A FR2799472B1 (fr) 1999-10-07 1999-10-07 Preparation d'adenovirus recombinants et de banques adenovirales
US16835699P 1999-12-01 1999-12-01

Publications (1)

Publication Number Publication Date
ZA200202481B true ZA200202481B (en) 2003-09-23

Family

ID=26235132

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200202481A ZA200202481B (en) 1999-10-07 2002-03-27 Recombinant adenoviruses preparation and adenovirus banks.

Country Status (22)

Country Link
US (1) US8263395B2 (xx)
EP (1) EP1224310B1 (xx)
JP (1) JP5260815B2 (xx)
KR (1) KR100928105B1 (xx)
CN (1) CN1384885B (xx)
AT (1) ATE355385T1 (xx)
AU (1) AU785431B2 (xx)
BR (1) BR0014489B1 (xx)
CA (1) CA2383225C (xx)
CZ (1) CZ302282B6 (xx)
DE (1) DE60033679T2 (xx)
DK (1) DK1224310T3 (xx)
FR (1) FR2799472B1 (xx)
HK (1) HK1050211B (xx)
HU (1) HU228933B1 (xx)
IL (2) IL148493A0 (xx)
MX (1) MXPA02003247A (xx)
NO (1) NO330916B1 (xx)
NZ (1) NZ518763A (xx)
PL (1) PL210590B1 (xx)
WO (1) WO2001025463A1 (xx)
ZA (1) ZA200202481B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001234980A1 (en) * 2000-02-09 2001-08-20 Genvec, Inc. Methods of preparing and using a viral vector library
EP2471909A1 (en) * 2010-12-30 2012-07-04 SIRION BIOTECH GmbH Nucleic acid molecules for generating adenoviral vectors
GB201322851D0 (en) * 2013-12-23 2014-02-12 Psioxus Therapeutics Ltd Method
CN109576231B (zh) * 2017-09-28 2022-03-25 北京康万达医药科技有限公司 分离的重组溶瘤腺病毒、药物组合物及其在治疗肿瘤和/或癌症的药物中的用途
JP7287611B2 (ja) * 2018-02-07 2023-06-06 学校法人日本医科大学 改良型アデノ随伴ウイルスベクター

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3486053T3 (de) 1983-10-20 2004-01-08 The Research Foundation Of State University Of New York Regulierung von Gen-Expression durch Translationshemmung unter Verwendung von m-RNS hinderndem Komplementär-RNS.
FR2573436B1 (fr) 1984-11-20 1989-02-17 Pasteur Institut Adn recombinant comportant une sequence nucleotidique codant pour un polypeptide determine sous le controle d'un promoteur d'adenovirus, vecteurs contenant cet adn recombinant, cellules eucaryotes transformees par cet adn recombinant, produits d'excretion de ces cellules transformees et leurs applications, notamment a la constitution de vaccins
US6696420B1 (en) * 1984-11-20 2004-02-24 Institut Pasteur Adenoviral vector with a deletion in the E1A coding region expressing a hetorologous protein
US6007806A (en) * 1986-08-13 1999-12-28 Transgene S.A. Expression of a tumor-specific antigen by a recombinant vector virus and use thereof in preventive or curative treatment of the corresponding tumor
FR2602790B1 (fr) 1986-08-13 1990-06-01 Transgene Sa Expression d'un antigene specifique de tumeur par un virus vecteur recombinant et utilisation de celui-ci pour le traitement preventif ou curatif de la tumeur correspondante
US5744133A (en) * 1986-08-13 1998-04-28 Transgene S.A. Expression of a tumor-specific antigen by a recombinant vector virus and use thereof in preventitive or curative treatment of the corresponding tumor
FR2688514A1 (fr) 1992-03-16 1993-09-17 Centre Nat Rech Scient Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant.
EP0673431A1 (en) 1992-12-03 1995-09-27 Genzyme Corporation Gene therapy for cystic fibrosis
FR2704556B1 (fr) 1993-04-30 1995-07-13 Rhone Poulenc Rorer Sa Virus recombinants et leur utilisation en thérapie génique.
FR2705363B1 (fr) 1993-05-13 1995-08-11 Clecim Sa Procédé de fusion de ferraille dans un four électrique et installation pour la mise en Óoeuvre du procédé.
FR2705361B1 (fr) 1993-05-18 1995-08-04 Centre Nat Rech Scient Vecteurs viraux et utilisation en thérapie génique.
FR2705686B1 (fr) * 1993-05-28 1995-08-18 Transgene Sa Nouveaux adénovirus défectifs et lignées de complémentation correspondantes.
US6133028A (en) * 1993-05-28 2000-10-17 Transgene S.A. Defective adenoviruses and corresponding complementation lines
CA2144040A1 (fr) 1993-07-13 1995-01-26 Michel Perricaudet Vecteurs adenoviraux defectifs et utilisation en therapie genique
FR2718150B1 (fr) * 1994-03-29 1996-04-26 Rhone Poulenc Rorer Sa Virus recombinants, préparation et utilisation en thérapie génique.
US7252989B1 (en) 1994-04-04 2007-08-07 Board Of Regents, The University Of Texas System Adenovirus supervector system
ATE336587T1 (de) 1994-06-10 2006-09-15 Genvec Inc Adenoviren-vektor systeme und zelllinien
FR2724945B1 (fr) * 1994-09-27 1996-12-27 Centre Nat Rech Scient Vecteurs viraux et utilisation en therapie genique
FR2726285B1 (fr) 1994-10-28 1996-11-29 Centre Nat Rech Scient Adenovirus depourvus de particules contaminantes viables, preparation et utilisation
FR2730504B1 (fr) * 1995-02-13 1997-03-28 Rhone Poulenc Rorer Sa Procede de preparation de genomes d'adenovirus recombinants
FR2730411B1 (fr) * 1995-02-14 1997-03-28 Centre Nat Rech Scient Association medicamenteuse utile pour la transfection et l'expression in vivo d'exogenes
AU724922B2 (en) * 1995-06-07 2000-10-05 Invitrogen Corporation Recombinational cloning using engineered recombination sites
US5783431A (en) * 1996-04-24 1998-07-21 Chromaxome Corporation Methods for generating and screening novel metabolic pathways
FR2749857B1 (fr) * 1996-06-12 1998-08-14 Centre Nat Rech Scient Generation de molecules replicatives in vivo
FR2755975B1 (fr) 1996-11-15 1999-05-07 Rhone Poulenc Rorer Sa Virus recombinants bicistroniques utiles pour le traitement de pathologies liees aux dyslipoproteinemies
US5846812A (en) * 1996-11-22 1998-12-08 Pioneer Hi-Bred International, Inc. Zearalenone detoxification compositions and methods
FR2774699B1 (fr) * 1997-11-17 2003-10-03 Rhone Poulenc Rorer Sa Methode de reduction des evenements de recombinaison homologue
US5922576A (en) * 1998-02-27 1999-07-13 The John Hopkins University Simplified system for generating recombinant adenoviruses
US6844270B2 (en) * 2000-11-26 2005-01-18 Shipley Company, L.L.C. Polymers and photoresist compositions for short wavelength imaging
SE523617C2 (sv) * 2001-10-01 2004-05-04 Sandvik Ab Skär för spånavskiljande bearbetning försedd med spånbrytande geometri
JP4308485B2 (ja) * 2002-07-08 2009-08-05 パナソニック株式会社 容量素子の製造方法
US6856551B2 (en) * 2003-02-06 2005-02-15 Sandisk Corporation System and method for programming cells in non-volatile integrated memory devices

Also Published As

Publication number Publication date
AU785431B2 (en) 2007-05-31
DE60033679T2 (de) 2007-11-15
HU228933B1 (en) 2013-06-28
BR0014489A (pt) 2002-06-04
US20090149349A1 (en) 2009-06-11
KR100928105B1 (ko) 2009-11-24
CA2383225A1 (fr) 2001-04-12
JP5260815B2 (ja) 2013-08-14
KR20020057969A (ko) 2002-07-12
IL148493A (en) 2010-04-15
CN1384885B (zh) 2011-06-22
BR0014489B1 (pt) 2013-05-21
AU7794700A (en) 2001-05-10
US8263395B2 (en) 2012-09-11
DE60033679D1 (de) 2007-04-12
EP1224310A1 (fr) 2002-07-24
WO2001025463A1 (fr) 2001-04-12
FR2799472A1 (fr) 2001-04-13
NZ518763A (en) 2005-01-28
CZ20021215A3 (cs) 2002-08-14
HK1050211B (zh) 2008-01-25
ATE355385T1 (de) 2006-03-15
IL148493A0 (en) 2002-09-12
CN1384885A (zh) 2002-12-11
FR2799472B1 (fr) 2004-07-16
PL354099A1 (en) 2003-12-29
JP2003512823A (ja) 2003-04-08
HUP0203801A2 (hu) 2003-03-28
CZ302282B6 (cs) 2011-02-02
DK1224310T3 (da) 2007-07-02
MXPA02003247A (es) 2002-09-30
HUP0203801A3 (en) 2005-01-28
CA2383225C (fr) 2011-12-13
NO330916B1 (no) 2011-08-15
NO20021634L (no) 2002-06-04
HK1050211A1 (en) 2003-06-13
PL210590B1 (pl) 2012-02-29
EP1224310B1 (fr) 2007-02-28
NO20021634D0 (no) 2002-04-05

Similar Documents

Publication Publication Date Title
EP1180932A4 (en) ADENOVIRUS WITH REINFORCED AND CONDITIONALLY REPLICATED INFECTIVE POWER, AND APPLICATIONS THEREOF
WO1997049827A3 (en) Adenoviral mediated gene transfer in adipocytes and related implants
IL132951A0 (en) Compounds preparation and use for transferring nucleic acids into cells
WO2001023592A3 (en) Methods for making recombinant proteins using apoptosis inhibitors
EP1775345A3 (en) Vector constructors
WO2002024640A3 (en) Recombinant adenovirus vectors that are replication-competent in tert-expressing cells
AU1741601A (en) Mesenchymal stem cells and/or progenitor cells, their isolation and use
IL206604A (en) Protein @ trans @membrane @@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ @@
WO2004099422A3 (en) Adenovirus particles with enhanced infectivity of dendritic cells and particles with decreased infectivity of hepatocytes
WO1997026322A3 (en) Methods and compositions for inhibiting hexokinase
WO2000042208A8 (en) Adenovirus vectors, packaging cell lines, compositions, and methods for preparation and use
EP1070122A4 (en) INDUCTION OF THE EXPRESSION OF APOPTOTIC OR CYTOTOXIC GENES BY CO-SUPPORT OF ADENOVIRAL MEDIATED GENES
HK1048593A1 (zh) 用於通過體內基因輸送治療心血管疾病的技術和組合物
IL148493A0 (en) Recombinant adenovirus preparation and adenovirus banks
IL162343A0 (en) Cell constructs cultured in vitro, preparation anduses
AU4378996A (en) Cell compositions for use in transplantation and ex vivo gene therapy
MXPA05004074A (es) Nuevos adenovirus, acidos nucleicos que los codifican y su uso.
FR2778670B1 (fr) Methodes et compositions pour la production de particules virales
CA2441535A1 (en) Methods for delivering nucleic acid molecules into cells and assessment thereof
AU2001253812A1 (en) In vivo loading of mhc
WO2000004918A3 (de) Mittel zur immuntherapie von tumorerkrankungen
GB2379446A (en) Cells,culture methods and their uses
AU3804997A (en) Vectors for inhibiting HIV and tumor growth
MXPA03003983A (es) Formulaciones que comprenden polimeros de dextrina en combinacion con azucares para la administracion de acidos nucleicos.
AU2000265672A1 (en) Somatic cloning gene transfer for the production of recombinant proteins, cells and organs