HK1048593A1 - 用於通過體內基因輸送治療心血管疾病的技術和組合物 - Google Patents
用於通過體內基因輸送治療心血管疾病的技術和組合物Info
- Publication number
- HK1048593A1 HK1048593A1 HK03100751.6A HK03100751A HK1048593A1 HK 1048593 A1 HK1048593 A1 HK 1048593A1 HK 03100751 A HK03100751 A HK 03100751A HK 1048593 A1 HK1048593 A1 HK 1048593A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- vivo
- compositions
- techniques
- cardiovascular disease
- gene delivery
- Prior art date
Links
- 208000024172 Cardiovascular disease Diseases 0.000 title 1
- 238000001476 gene delivery Methods 0.000 title 1
- 238000001727 in vivo Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/025—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a parvovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43515699A | 1999-11-05 | 1999-11-05 | |
US60908000A | 2000-06-30 | 2000-06-30 | |
PCT/US2000/030345 WO2001034208A1 (en) | 1999-11-05 | 2000-11-03 | Techniques and compositions for treating cardiovascular disease by in vivo gene delivery |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1048593A1 true HK1048593A1 (zh) | 2003-04-11 |
Family
ID=27030448
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK03100751.6A HK1048593A1 (zh) | 1999-11-05 | 2003-01-29 | 用於通過體內基因輸送治療心血管疾病的技術和組合物 |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1225921A1 (zh) |
JP (1) | JP2003513942A (zh) |
KR (1) | KR20020049031A (zh) |
CN (1) | CN1433325A (zh) |
AU (1) | AU784392B2 (zh) |
CA (1) | CA2389524A1 (zh) |
EA (1) | EA008538B1 (zh) |
HK (1) | HK1048593A1 (zh) |
NZ (1) | NZ546670A (zh) |
WO (1) | WO2001034208A1 (zh) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1433325A (zh) * | 1999-11-05 | 2003-07-30 | 加利福尼亚大学董事会 | 通过体内基因递送治疗心血管疾病的技术和组合物 |
US20030093147A1 (en) * | 2001-11-13 | 2003-05-15 | Ogle Matthew F. | Medical devices that stimulate growth factor production |
KR100562824B1 (ko) | 2002-03-20 | 2006-03-23 | 주식회사 바이로메드 | 유전자 발현효율이 높으며 간세포 성장인자의 두 가지이형체를 동시에 발현하는 하이브리드 간세포 성장인자유전자 |
PL195457B1 (pl) * | 2002-08-05 | 2007-09-28 | Zaklady Farm Polpharma Sa | Kaseta ekspresyjna, dwucistronowy wektor plazmidowy, środek farmaceutyczny oraz ich zastosowanie |
CA2658628A1 (en) * | 2006-07-25 | 2008-01-31 | Celladon Corporation | Extended antegrade epicardial coronary infusion of adeno-associated viral vectors for gene therapy |
PL2197900T3 (pl) * | 2007-08-24 | 2012-12-31 | Univ Wuerzburg J Maximilians | Zmutowane podwójnie cyklizowane peptydy receptorowe hamujące przeciwciała przeciwko beta 1-adrenoreceptorowi |
BRPI0911511B8 (pt) | 2008-04-09 | 2021-05-25 | Helixmith Co Ltd | formulação de dna liofilizadas para aumentar a expressão de dna de plasmídeo |
WO2010078624A1 (en) * | 2009-01-07 | 2010-07-15 | Vegenics Limited | Materials and methods for the treatment of hypertension |
KR101006106B1 (ko) * | 2009-06-04 | 2011-01-07 | 김현태 | 전·자기장 차단 전열선 |
US10155099B2 (en) | 2009-09-21 | 2018-12-18 | Cook Regentec Llc | Method for infusing stem cells |
HUE036640T2 (hu) * | 2012-02-14 | 2018-07-30 | Univ California | Parakrin gének szisztémás bejuttatása és szabályozott expressziója szív és érrendszeri betegségekre és egyéb állapotokra |
KR20150016970A (ko) | 2012-06-05 | 2015-02-13 | 머핀 인코포레이티드 | 세포 치료요법에 유용한 카테터 시스템 및 방법 |
BR112016008267A2 (pt) | 2013-10-22 | 2017-10-03 | Viromed Co Ltd | Composição para prevenir ou tratar esclerose lateral amiotrófica usando duas ou mais isoformas de fator de crescimento de hepatócito |
US20210393805A1 (en) * | 2018-05-16 | 2021-12-23 | University Of Massachusetts | Perfusion-based delivery of recombinant aav vectors for expression of secreted proteins |
AU2019305221A1 (en) | 2018-07-19 | 2021-02-18 | Helixmith Co., Ltd. | Lyophilized pharmaceutical compositions for naked DNA gene therapy |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1136920C (zh) * | 1995-02-28 | 2004-02-04 | 加利福尼亚大学董事会 | 基因转移介导的血管形成疗法 |
US5792453A (en) * | 1995-02-28 | 1998-08-11 | The Regents Of The University Of California | Gene transfer-mediated angiogenesis therapy |
AU745409B2 (en) * | 1997-01-29 | 2002-03-21 | Cornell Research Foundation Inc. | Multiple site delivery of adenoviral vector for the induction of angiogenesis |
KR20070005030A (ko) * | 1997-05-06 | 2007-01-09 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 혈관형성성 트랜스유전자의 생체내 송달에 의한 심장 질환및 심실 리모델링을 치료하기 위한 방법 및 조성물 |
CN101186928A (zh) * | 1998-02-11 | 2008-05-28 | 加利福尼亚大学董事会 | 核酸和血管活性剂相组合用于加强的基因投递 |
AU763049B2 (en) * | 1998-12-28 | 2003-07-10 | Arch Development Corporation | Efficient and stable (in vivo) gene transfer to cardiomyocytes using recombinantadeno-associated virus vectors |
CN1433325A (zh) * | 1999-11-05 | 2003-07-30 | 加利福尼亚大学董事会 | 通过体内基因递送治疗心血管疾病的技术和组合物 |
-
2000
- 2000-11-03 CN CN00816481A patent/CN1433325A/zh active Pending
- 2000-11-03 KR KR1020027005855A patent/KR20020049031A/ko not_active Application Discontinuation
- 2000-11-03 AU AU14604/01A patent/AU784392B2/en not_active Ceased
- 2000-11-03 EP EP00976894A patent/EP1225921A1/en not_active Withdrawn
- 2000-11-03 EA EA200200533A patent/EA008538B1/ru not_active IP Right Cessation
- 2000-11-03 WO PCT/US2000/030345 patent/WO2001034208A1/en active Application Filing
- 2000-11-03 NZ NZ546670A patent/NZ546670A/en not_active IP Right Cessation
- 2000-11-03 CA CA002389524A patent/CA2389524A1/en not_active Abandoned
- 2000-11-03 JP JP2001536204A patent/JP2003513942A/ja active Pending
-
2003
- 2003-01-29 HK HK03100751.6A patent/HK1048593A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
AU784392B2 (en) | 2006-03-23 |
AU1460401A (en) | 2001-06-06 |
EP1225921A1 (en) | 2002-07-31 |
EA008538B1 (ru) | 2007-06-29 |
WO2001034208A1 (en) | 2001-05-17 |
NZ546670A (en) | 2009-02-28 |
JP2003513942A (ja) | 2003-04-15 |
CA2389524A1 (en) | 2001-05-17 |
EA200200533A1 (ru) | 2002-12-26 |
CN1433325A (zh) | 2003-07-30 |
KR20020049031A (ko) | 2002-06-24 |
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