HUE036640T2 - Parakrin gének szisztémás bejuttatása és szabályozott expressziója szív és érrendszeri betegségekre és egyéb állapotokra - Google Patents
Parakrin gének szisztémás bejuttatása és szabályozott expressziója szív és érrendszeri betegségekre és egyéb állapotokraInfo
- Publication number
- HUE036640T2 HUE036640T2 HUE13749674A HUE13749674A HUE036640T2 HU E036640 T2 HUE036640 T2 HU E036640T2 HU E13749674 A HUE13749674 A HU E13749674A HU E13749674 A HUE13749674 A HU E13749674A HU E036640 T2 HUE036640 T2 HU E036640T2
- Authority
- HU
- Hungary
- Prior art keywords
- paracrine
- genes
- conditions
- cardiovascular diseases
- systemic delivery
- Prior art date
Links
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261598772P | 2012-02-14 | 2012-02-14 |
Publications (1)
Publication Number | Publication Date |
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HUE036640T2 true HUE036640T2 (hu) | 2018-07-30 |
Family
ID=48984885
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE13749674A HUE036640T2 (hu) | 2012-02-14 | 2013-02-13 | Parakrin gének szisztémás bejuttatása és szabályozott expressziója szív és érrendszeri betegségekre és egyéb állapotokra |
Country Status (18)
Country | Link |
---|---|
US (3) | US20150118287A1 (hu) |
EP (2) | EP3311830A1 (hu) |
JP (3) | JP6562632B2 (hu) |
KR (1) | KR102107482B1 (hu) |
CN (2) | CN108310396B (hu) |
AU (2) | AU2013221615B2 (hu) |
BR (1) | BR112014020127A2 (hu) |
CA (1) | CA2864100A1 (hu) |
DK (1) | DK2814513T3 (hu) |
ES (1) | ES2660492T3 (hu) |
HK (2) | HK1203845A1 (hu) |
HU (1) | HUE036640T2 (hu) |
IL (3) | IL234007A0 (hu) |
IN (1) | IN2014DN06789A (hu) |
PL (1) | PL2814513T3 (hu) |
PT (1) | PT2814513T (hu) |
RU (1) | RU2642605C2 (hu) |
WO (1) | WO2013123094A2 (hu) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010138263A2 (en) | 2009-05-28 | 2010-12-02 | University Of Massachusetts | Novel aav 's and uses thereof |
KR102107482B1 (ko) * | 2012-02-14 | 2020-05-08 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 심혈관 질환 및 다른 증상에 대한 파라크린 유전자의 전신 전달 및 조절 발현 |
US20170182129A1 (en) * | 2014-04-03 | 2017-06-29 | The Regents Of The University Of California | Systemic delivery of virus vectors encoding urocortin-2 and related genes to treat diabetes-related cardiac dysfunctions and congestive heart failure |
US10577627B2 (en) | 2014-06-09 | 2020-03-03 | Voyager Therapeutics, Inc. | Chimeric capsids |
US10480011B2 (en) * | 2014-10-21 | 2019-11-19 | University Of Massachusetts | Recombinant AAV variants and uses thereof |
CA2966620A1 (en) | 2014-11-05 | 2016-05-12 | Voyager Therapeutics, Inc. | Aadc polynucleotides for the treatment of parkinson's disease |
EP3218484A4 (en) | 2014-11-14 | 2018-05-30 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
US10570395B2 (en) | 2014-11-14 | 2020-02-25 | Voyager Therapeutics, Inc. | Modulatory polynucleotides |
US11697825B2 (en) | 2014-12-12 | 2023-07-11 | Voyager Therapeutics, Inc. | Compositions and methods for the production of scAAV |
CN107531752B (zh) * | 2015-05-12 | 2022-05-10 | 加利福尼亚大学董事会 | 用于炎症和纤维化的肽治疗 |
CN108025047B (zh) * | 2015-05-28 | 2021-11-19 | 康奈尔大学 | 腺相关病毒介导的c1ei递送作为用于血管性水肿的疗法 |
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