PL2197900T3 - Zmutowane podwójnie cyklizowane peptydy receptorowe hamujące przeciwciała przeciwko beta 1-adrenoreceptorowi - Google Patents

Zmutowane podwójnie cyklizowane peptydy receptorowe hamujące przeciwciała przeciwko beta 1-adrenoreceptorowi

Info

Publication number
PL2197900T3
PL2197900T3 PL08801676T PL08801676T PL2197900T3 PL 2197900 T3 PL2197900 T3 PL 2197900T3 PL 08801676 T PL08801676 T PL 08801676T PL 08801676 T PL08801676 T PL 08801676T PL 2197900 T3 PL2197900 T3 PL 2197900T3
Authority
PL
Poland
Prior art keywords
receptor peptides
inhibiting beta
peptides inhibiting
mutant double
cyclized
Prior art date
Application number
PL08801676T
Other languages
English (en)
Inventor
Roland Jahns
Valérie Jahns
Martin Lohse
Viacheslav Nikolaev
Original Assignee
Univ Wuerzburg J Maximilians
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wuerzburg J Maximilians filed Critical Univ Wuerzburg J Maximilians
Publication of PL2197900T3 publication Critical patent/PL2197900T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
PL08801676T 2007-08-24 2008-08-22 Zmutowane podwójnie cyklizowane peptydy receptorowe hamujące przeciwciała przeciwko beta 1-adrenoreceptorowi PL2197900T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07016637 2007-08-24
PCT/EP2008/006932 WO2009027063A2 (en) 2007-08-24 2008-08-22 MUTANT DOUBLE CYCLIZED RECEPTOR PEPTIDES INHIBITING β1-ADRENOCEPTOR ANTIBODIES
EP08801676A EP2197900B9 (en) 2007-08-24 2008-08-22 Mutant double cyclized receptor peptides inhibiting beta 1-adrenoceptor antibodies

Publications (1)

Publication Number Publication Date
PL2197900T3 true PL2197900T3 (pl) 2012-12-31

Family

ID=40130559

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08801676T PL2197900T3 (pl) 2007-08-24 2008-08-22 Zmutowane podwójnie cyklizowane peptydy receptorowe hamujące przeciwciała przeciwko beta 1-adrenoreceptorowi

Country Status (14)

Country Link
US (1) US9062095B2 (pl)
EP (3) EP2197900B9 (pl)
JP (3) JP5248610B2 (pl)
CN (2) CN101835793B (pl)
AU (1) AU2008291296B2 (pl)
CA (1) CA2697108C (pl)
DK (1) DK2197900T3 (pl)
ES (1) ES2391358T3 (pl)
HK (1) HK1176363A1 (pl)
HR (1) HRP20120827T1 (pl)
PL (1) PL2197900T3 (pl)
PT (1) PT2197900E (pl)
SI (1) SI2197900T1 (pl)
WO (1) WO2009027063A2 (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9062095B2 (en) * 2007-08-24 2015-06-23 Julius-Maximilians-Universtitat-Wurzburg Mutant double cyclized receptor peptides inhibiting β1-adrenoceptor antibodies
BRPI1007007A2 (pt) * 2009-01-27 2016-03-22 Julius Maximilians Universität Würzburg peptídeos cíclico, molécula de ácido nucleico, vetor, célula hospedeira, método para produção de um peptídeo cíclico, composição farmacêutica, método para detecção de anticorpos contra um b-ar (em uma amostra)
DE102010018878B4 (de) 2009-04-30 2013-09-26 Julius-Maximilians-Universität Würzburg Neue Zell-Linie zur Fluoreszenz-basierten Detektion von funktionell aktiven Antikörpern und Autoantikörpern gegen den Beta1-adrenergen Rezeptor
EP2402016A1 (en) * 2010-06-29 2012-01-04 Charité - Universitätsmedizin Berlin Aptamers that inhibit interaction between antibody and 1st or 2nd extracellular loop of human beta-1-adrenergic receptor
CA2835231A1 (en) 2011-06-10 2012-12-13 Corimmun Gmbh Binding compounds to human .beta.1-adrenoreceptor (.beta.1-ar) and their use in the measurement of auto-anti-.beta.1-ar antibodies
NZ628126A (en) 2012-02-16 2016-10-28 Atyr Pharma Inc Histidyl-trna synthetases for treating autoimmune and inflammatory diseases
DK3460054T3 (da) 2013-03-15 2021-01-18 Atyr Pharma Inc Histidyl-tRNA-syntetase-Fc-konjugater
WO2015022953A1 (ja) * 2013-08-14 2015-02-19 株式会社新日本科学 血液脳関門障害改善剤
CA3060514A1 (en) 2017-04-20 2018-10-25 Atyr Pharma, Inc. Compositions and methods for treating lung inflammation
CN108218963B (zh) * 2018-01-19 2020-10-13 首都医科大学 一种环肽及其制备方法和用途
SG11202109424RA (en) * 2019-03-14 2021-09-29 Genentech Inc Treatment of cancer with her2xcd3 bispecific antibodies in combination with anti-her2 mab
US11986536B2 (en) 2019-03-23 2024-05-21 Ablevia Biotech Gmbh Compound for the sequestration of undesirable antibodies in a patient
KR20230074641A (ko) * 2020-09-23 2023-05-30 아블레비아 바이오테크 게엠베하 자가항체-매개 병태의 예방 또는 치료를 위한 화합물
CN112266330B (zh) * 2020-10-15 2023-02-24 长沙博源医疗科技有限公司 一种甲氧基肾上腺素衍生物、免疫原、抗甲氧基肾上腺素特异性抗体及其制备方法与应用
WO2023028590A1 (en) * 2021-08-27 2023-03-02 Yale University Molecular degraders of extracellular proteins
JP2023117892A (ja) * 2022-02-14 2023-08-24 公益財団法人 鷹揚郷 ヘプシジン結合ペプチド

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4711955A (en) 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
CA1223831A (en) 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
US4880635B1 (en) 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
US5792608A (en) 1991-12-12 1998-08-11 Gilead Sciences, Inc. Nuclease stable and binding competent oligomers and methods for their use
US5525711A (en) 1994-05-18 1996-06-11 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pteridine nucleotide analogs as fluorescent DNA probes
JP2003514772A (ja) * 1999-09-21 2003-04-22 アフィーナ イミュンテヒニク ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｄｃｍを引き起こす自己抗体に対するペプチド
CN1433325A (zh) * 1999-11-05 2003-07-30 加利福尼亚大学董事会 通过体内基因递送治疗心血管疾病的技术和组合物
US20040001827A1 (en) * 2002-06-28 2004-01-01 Dennis Mark S. Serum albumin binding peptides for tumor targeting
JP4541490B2 (ja) 2000-04-07 2010-09-08 株式会社カネカ 拡張型心筋症用吸着体
WO2001083693A2 (en) 2000-04-28 2001-11-08 Glaxo Group Limited Compounds having affinity for the vascular endothelial growth factor receptor-2 (vegfr-2) and associated uses
KR20040004538A (ko) * 2001-08-23 2004-01-13 질랜드 파마 에이/에스 세포간 커뮤니케이션을 촉진시켜주는 화합물의 신규한의약적 용도
AU2003225922A1 (en) * 2002-03-26 2003-10-13 Dyax Corp Fibrinogen binding moieties
WO2004069863A2 (en) * 2003-02-04 2004-08-19 New York University Constrained hiv v3 loop peptides as immunogens and receptor antagonists
EP1536020A1 (en) 2003-11-26 2005-06-01 Bayerische Julius-Maximilians-Universität Würzburg Means and methods for optical determination of cAMP in vitro and in vivo
ES2441177T3 (es) * 2005-03-31 2014-02-03 Julius-Maximilians-Universität Würzburg Medios para la inhibición de anticuerpos anti-receptor 1-adrenérgico
US9062095B2 (en) * 2007-08-24 2015-06-23 Julius-Maximilians-Universtitat-Wurzburg Mutant double cyclized receptor peptides inhibiting β1-adrenoceptor antibodies

Also Published As

Publication number Publication date
ES2391358T3 (es) 2012-11-23
EP2559698A2 (en) 2013-02-20
CN101835793A (zh) 2010-09-15
HK1176363A1 (en) 2013-07-26
JP2013176369A (ja) 2013-09-09
JP2010536356A (ja) 2010-12-02
PT2197900E (pt) 2012-10-24
CA2697108C (en) 2018-05-22
AU2008291296B2 (en) 2014-02-06
CA2697108A1 (en) 2009-03-05
JP5248610B2 (ja) 2013-07-31
EP2197900A2 (en) 2010-06-23
EP2197900B1 (en) 2012-08-01
SI2197900T1 (sl) 2012-11-30
HRP20120827T1 (hr) 2012-11-30
US20100209445A1 (en) 2010-08-19
JP2013138679A (ja) 2013-07-18
WO2009027063A2 (en) 2009-03-05
EP2559698B1 (en) 2014-11-12
EP2497777A2 (en) 2012-09-12
EP2497777A3 (en) 2012-10-10
US9062095B2 (en) 2015-06-23
CN101835793B (zh) 2014-04-23
EP2559698A3 (en) 2013-03-06
DK2197900T3 (da) 2012-10-22
EP2197900B9 (en) 2013-01-09
WO2009027063A3 (en) 2009-07-23
AU2008291296A1 (en) 2009-03-05
CN103992406A (zh) 2014-08-20

Similar Documents

Publication Publication Date Title
HK1176363A1 (en) Mutant double cyclized receptor peptides inhibiting beta 1-adrenoceptor antibodies 1-
HK1244694A1 (zh) 新穎的胰高血糖素受體拮抗劑
HRP20151108T1 (en) Nogo receptor antagonists
EP2184278A4 (en) P2X4 RECEIVER ANTAGONIST
EP2151236A4 (en) G PROTEIN COUPLED RECEPTOR AGONIST
IL204536A0 (en) Anti - il -6 receptor antibody
EP2058304A4 (en) P2X4 RECEPTOR ANTAGONIST
ZA201001874B (en) Nmda receptor antagonists for neuroprotection
EP2099454A4 (en) AMINOPYRROLIDINES AS CHEMOKINE RECEPTOR ANTAGONISTS
ZA201001597B (en) Octahydropentalene compounds as chemokine receptor antagonists
HK1136302A1 (en) Progesterone receptor antagonists
IL212551A0 (en) Cxcr4 receptor compounds
IL187424A0 (en) C5a RECEPTOR ANTAGONISTS
ZA200705237B (en) C5A receptor antagonists
ZA201001125B (en) Pyrrolidine Aryl-Ether as NK3 receptor antagonists
ZA201000676B (en) Pyrrolidine aryl-ether as NK3 receptor antagonists
EP2191830A4 (en) SOLID PREPARATION COMPRISING A NPYY5 RECEPTOR ANTAGONIST
HK1163063A1 (en) Novel pyrazole-3-carboxamide derivate having 5-ht2b receptor antagonist activity 5-ht2b -3-
IL198542A0 (en) 2-aminoquinolines as 5-ht(5a)receptor antagonists
EP2153736A4 (en) NEW LEUKOTRIEN RECEPTOR ANTAGONIST
EP2478001A4 (en) BENEFICIAL PEPTIDE COMPOUNDS OF MU OPIACEOUS RECEPTOR
IL202454A0 (en) Urotensin ii receptor antagonists
EP2229400A4 (en) ADVANTAGEOUS SALTS OF MU-OPIOD RECEPTOR PEPTIDES
IL200380A0 (en) Mineralcorticoid receptor antagonists for the treatment of endometriosis
ZA200903499B (en) Indoles which act as via receptor antagonists