BR0013993A - Método de preparar um composto de tetraciclina substituìda, complexo quìmico reativo de tetraciclina, composto de tetraciclina 7-substituìdo, e, composto de tetraciclina 9-substituìdo - Google Patents

Método de preparar um composto de tetraciclina substituìda, complexo quìmico reativo de tetraciclina, composto de tetraciclina 7-substituìdo, e, composto de tetraciclina 9-substituìdo

Info

Publication number
BR0013993A
BR0013993A BR0013993-9A BR0013993A BR0013993A BR 0013993 A BR0013993 A BR 0013993A BR 0013993 A BR0013993 A BR 0013993A BR 0013993 A BR0013993 A BR 0013993A
Authority
BR
Brazil
Prior art keywords
tetracycline
substituted
tetracycline compound
compound
reactive
Prior art date
Application number
BR0013993-9A
Other languages
English (en)
Portuguese (pt)
Inventor
Mark L Nelson
Glen Rennie
Darrell J Koza
Original Assignee
Tufts College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tufts College filed Critical Tufts College
Publication of BR0013993A publication Critical patent/BR0013993A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BR0013993-9A 1999-09-14 2000-09-13 Método de preparar um composto de tetraciclina substituìda, complexo quìmico reativo de tetraciclina, composto de tetraciclina 7-substituìdo, e, composto de tetraciclina 9-substituìdo BR0013993A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15470199P 1999-09-14 1999-09-14
US23209100P 2000-09-12 2000-09-12
PCT/US2000/025040 WO2001019784A1 (en) 1999-09-14 2000-09-13 Methods of preparing substituted tetracyclines with transition metal-based chemistries

Publications (1)

Publication Number Publication Date
BR0013993A true BR0013993A (pt) 2002-07-02

Family

ID=26851695

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0013993-9A BR0013993A (pt) 1999-09-14 2000-09-13 Método de preparar um composto de tetraciclina substituìda, complexo quìmico reativo de tetraciclina, composto de tetraciclina 7-substituìdo, e, composto de tetraciclina 9-substituìdo

Country Status (21)

Country Link
US (3) US6617318B1 (https=)
EP (5) EP2327687A3 (https=)
JP (2) JP5093953B2 (https=)
KR (1) KR100764992B1 (https=)
CN (2) CN102336680A (https=)
AT (2) ATE323671T1 (https=)
AU (3) AU781439C (https=)
BR (1) BR0013993A (https=)
CA (2) CA2672722C (https=)
CY (1) CY1105094T1 (https=)
CZ (1) CZ301835B6 (https=)
DE (1) DE60027465T2 (https=)
DK (1) DK1240133T3 (https=)
EA (3) EA016099B1 (https=)
ES (1) ES2260051T3 (https=)
HR (1) HRP20020322B1 (https=)
HU (1) HUP0202798A3 (https=)
IL (4) IL148482A0 (https=)
MX (1) MXPA02002595A (https=)
PT (1) PT1240133E (https=)
WO (1) WO2001019784A1 (https=)

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US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
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AU3105801A (en) 2000-01-24 2001-07-31 Trustees Of Tufts College Tetracycline compounds for treatment of cryptosporidium parvum related disorders
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PT1240133E (pt) 2006-07-31
AU781439B2 (en) 2005-05-26
AU2009225351A1 (en) 2009-11-05
HRP20020322B1 (en) 2009-04-30
EA200400944A1 (ru) 2005-04-28
IL183124A (en) 2012-05-31
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US20060166946A1 (en) 2006-07-27
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EA012203B1 (ru) 2009-08-28
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CA2383364A1 (en) 2001-03-22
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