ES8305347A1 - "procedimiento para la fabricacion de derivados de las (tienil-2)- y (tienil-3)-2 etilaminas". - Google Patents
"procedimiento para la fabricacion de derivados de las (tienil-2)- y (tienil-3)-2 etilaminas".Info
- Publication number
- ES8305347A1 ES8305347A1 ES514191A ES514191A ES8305347A1 ES 8305347 A1 ES8305347 A1 ES 8305347A1 ES 514191 A ES514191 A ES 514191A ES 514191 A ES514191 A ES 514191A ES 8305347 A1 ES8305347 A1 ES 8305347A1
- Authority
- ES
- Spain
- Prior art keywords
- give
- thienyl
- alkyl
- substd
- heterocycle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 3
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 2
- -1 nitro, cyano, amino, carboxy Chemical group 0.000 abstract 2
- 125000000022 2-aminoethyl group Chemical group [H]C([*])([H])C([H])([H])N([H])[H] 0.000 abstract 1
- 125000001541 3-thienyl group Chemical group S1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000004986 diarylamino group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003947 ethylamines Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
- C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Liquid Deposition Of Substances Of Which Semiconductor Devices Are Composed (AREA)
- Saccharide Compounds (AREA)
- Compositions Of Oxide Ceramics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Vehicle Body Suspensions (AREA)
- Electrical Control Of Air Or Fuel Supplied To Internal-Combustion Engine (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE (TIENIL-2)- Y (TIENIL-3)-2 ETILAMINAS, DE FORMULA (I), EN LA QUE R , R Y AR PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA TRANSFORMACION DEL CARBANION DE FORMULA (II), EN LA QUE R , X E Y PUEDEN SER VARIOS TIPOS DE RADICALES, POR CALENTAMIENTO ENTRE -78 C Y 150 C; SEGUIDA DE HIDROLISIS Y REDUCCION CON UN AGENTE REDUCTOR, TAL COMO BOROHIDRURO SODICO; REACCION CON UNA BASE DE FORMULA B~PM~O; TRATAMIENTO CON UN DERIVADO HALOGENADO DE FORMULA AR-CHX-R , EN LA QUE X ES UN HALOGENO, Y AR Y R SON LOS MISMOS QUE EN LA FORMULA (I); Y, FINALMENTE, REACCION CON UN ACIDO MINERAL U ORGANICO. ESTOS COMPUESTOS TIENEN APLICACIONES COMO INTERMEDIOS EN PROCESOS DE SINTESIS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8113064A FR2508455A1 (fr) | 1981-06-30 | 1981-06-30 | Procede de preparation de derives des (thienyl-2)- et (thienyl-3)-2 ethylamines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8305347A1 true ES8305347A1 (es) | 1983-04-01 |
| ES514191A0 ES514191A0 (es) | 1983-04-01 |
Family
ID=9260131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES514191A Granted ES514191A0 (es) | 1981-06-30 | 1982-06-14 | "procedimiento para la fabricacion de derivados de las (tienil-2)- y (tienil-3)-2 etilaminas". |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4458086A (es) |
| EP (1) | EP0068983B1 (es) |
| JP (1) | JPS5813583A (es) |
| KR (1) | KR840000538A (es) |
| AT (1) | ATE18764T1 (es) |
| AU (1) | AU549063B2 (es) |
| CA (1) | CA1205808A (es) |
| CS (1) | CS244112B2 (es) |
| DD (1) | DD202712A5 (es) |
| DE (1) | DE3270081D1 (es) |
| DK (1) | DK289482A (es) |
| ES (1) | ES514191A0 (es) |
| FI (1) | FI822317L (es) |
| FR (1) | FR2508455A1 (es) |
| GR (1) | GR77205B (es) |
| HU (1) | HU194861B (es) |
| IE (1) | IE53242B1 (es) |
| IL (1) | IL65982A (es) |
| NO (1) | NO155344C (es) |
| NZ (1) | NZ200854A (es) |
| PT (1) | PT75154B (es) |
| SU (1) | SU1181543A3 (es) |
| YU (1) | YU142882A (es) |
| ZA (1) | ZA824616B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6145A (ja) * | 1984-06-09 | 1986-01-06 | Kaken Pharmaceut Co Ltd | Ｎ‐（４‐ｔｅｒｔ‐ブチルベンジル）‐Ｎ‐メチル‐１‐ナフチルメチルアミンおよびそれを有効成分とする抗真菌剤 |
| US5334628A (en) * | 1984-06-09 | 1994-08-02 | Kaken Pharmaceutical Co., Ltd. | Amine derivatives, processes for preparing the same and fungicides containing the same |
| EP0253595A3 (en) * | 1986-07-16 | 1988-12-14 | COOKSON GROUP plc | Novel pyrrole monomers and polymers prepared therefrom |
| FR2624860B1 (fr) * | 1987-12-18 | 1990-06-01 | Sanofi Sa | Procede de preparation de la n-(chloro-2 benzyl) (thienyl-2)-2 ethylamine |
| US4900539A (en) * | 1988-12-22 | 1990-02-13 | The United States Of America As Represented By The United States Department Of Energy | Radiohalogenated thienylethylamine derivatives for evaluating local cerebral blood flow |
| US7820180B2 (en) * | 2004-09-24 | 2010-10-26 | The Trustees Of The University Of Pennsylvania | Listeria-based and LLO-based vaccines |
| HU225504B1 (en) | 1997-05-13 | 2007-01-29 | Sanofi Aventis | Novel halophenyl-(2-(2-thienyl)-ethylamino)-acetonitriles and process for producing them |
-
1981
- 1981-06-30 FR FR8113064A patent/FR2508455A1/fr active Granted
-
1982
- 1982-06-01 IE IE1312/82A patent/IE53242B1/en unknown
- 1982-06-04 NZ NZ200854A patent/NZ200854A/xx unknown
- 1982-06-06 IL IL65982A patent/IL65982A/xx unknown
- 1982-06-09 GR GR68376A patent/GR77205B/el unknown
- 1982-06-10 AU AU84756/82A patent/AU549063B2/en not_active Ceased
- 1982-06-14 ES ES514191A patent/ES514191A0/es active Granted
- 1982-06-17 DE DE8282401101T patent/DE3270081D1/de not_active Expired
- 1982-06-17 EP EP82401101A patent/EP0068983B1/fr not_active Expired
- 1982-06-17 AT AT82401101T patent/ATE18764T1/de not_active IP Right Cessation
- 1982-06-25 SU SU823456110A patent/SU1181543A3/ru active
- 1982-06-28 DK DK289482A patent/DK289482A/da not_active Application Discontinuation
- 1982-06-29 CA CA000406266A patent/CA1205808A/en not_active Expired
- 1982-06-29 ZA ZA824616A patent/ZA824616B/xx unknown
- 1982-06-29 US US06/393,388 patent/US4458086A/en not_active Expired - Fee Related
- 1982-06-29 NO NO822226A patent/NO155344C/no unknown
- 1982-06-29 DD DD82241199A patent/DD202712A5/de unknown
- 1982-06-29 FI FI822317A patent/FI822317L/fi not_active Application Discontinuation
- 1982-06-29 CS CS824897A patent/CS244112B2/cs unknown
- 1982-06-29 PT PT75154A patent/PT75154B/pt not_active IP Right Cessation
- 1982-06-29 HU HU822108A patent/HU194861B/hu unknown
- 1982-06-30 YU YU01428/82A patent/YU142882A/xx unknown
- 1982-06-30 JP JP57113844A patent/JPS5813583A/ja active Pending
- 1982-06-30 KR KR1019820002914A patent/KR840000538A/ko unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SU1181543A3 (ru) | 1985-09-23 |
| IE821312L (en) | 1982-12-30 |
| US4458086A (en) | 1984-07-03 |
| EP0068983B1 (fr) | 1986-03-26 |
| KR840000538A (ko) | 1984-02-25 |
| ATE18764T1 (de) | 1986-04-15 |
| NO155344C (no) | 1987-03-18 |
| YU142882A (en) | 1984-12-31 |
| PT75154B (fr) | 1984-05-29 |
| DK289482A (da) | 1982-12-31 |
| ZA824616B (en) | 1983-04-27 |
| GR77205B (es) | 1984-09-11 |
| FR2508455B1 (es) | 1984-01-06 |
| FI822317A0 (fi) | 1982-06-29 |
| IL65982A (en) | 1985-09-29 |
| AU549063B2 (en) | 1986-01-09 |
| EP0068983A1 (fr) | 1983-01-05 |
| NO155344B (no) | 1986-12-08 |
| FR2508455A1 (fr) | 1982-12-31 |
| IL65982A0 (en) | 1982-09-30 |
| AU8475682A (en) | 1983-01-06 |
| NO822226L (no) | 1983-01-03 |
| DE3270081D1 (en) | 1986-04-30 |
| CA1205808A (en) | 1986-06-10 |
| PT75154A (fr) | 1982-07-01 |
| DD202712A5 (de) | 1983-09-28 |
| CS244112B2 (en) | 1986-07-17 |
| FI822317L (fi) | 1982-12-31 |
| CS489782A2 (en) | 1985-08-15 |
| JPS5813583A (ja) | 1983-01-26 |
| IE53242B1 (en) | 1988-09-14 |
| NZ200854A (en) | 1985-09-13 |
| ES514191A0 (es) | 1983-04-01 |
| HU194861B (en) | 1988-03-28 |
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