BR0008760A - Genes pks da schizochytrium - Google Patents
Genes pks da schizochytriumInfo
- Publication number
- BR0008760A BR0008760A BR0008760-2A BR0008760A BR0008760A BR 0008760 A BR0008760 A BR 0008760A BR 0008760 A BR0008760 A BR 0008760A BR 0008760 A BR0008760 A BR 0008760A
- Authority
- BR
- Brazil
- Prior art keywords
- production
- genes
- pks
- long
- plants
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 241000233671 Schizochytrium Species 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 5
- 235000020978 long-chain polyunsaturated fatty acids Nutrition 0.000 abstract 3
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 2
- DVSZKTAMJJTWFG-UHFFFAOYSA-N docosa-2,4,6,8,10,12-hexaenoic acid Chemical compound CCCCCCCCCC=CC=CC=CC=CC=CC=CC(O)=O DVSZKTAMJJTWFG-UHFFFAOYSA-N 0.000 abstract 2
- 229930195729 fatty acid Natural products 0.000 abstract 2
- 239000000194 fatty acid Substances 0.000 abstract 2
- 150000004665 fatty acids Chemical class 0.000 abstract 2
- 241000294598 Moritella marina Species 0.000 abstract 1
- 241000863432 Shewanella putrefaciens Species 0.000 abstract 1
- 108700019146 Transgenes Proteins 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
- MBMBGCFOFBJSGT-KUBAVDMBSA-N docosahexaenoic acid Natural products CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 abstract 1
- SBHCLVQMTBWHCD-UHFFFAOYSA-N icosa-2,4,6,8,10-pentaenoic acid Chemical compound CCCCCCCCCC=CC=CC=CC=CC=CC(O)=O SBHCLVQMTBWHCD-UHFFFAOYSA-N 0.000 abstract 1
- 238000011031 large-scale manufacturing process Methods 0.000 abstract 1
- 150000004668 long chain fatty acids Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 239000003921 oil Substances 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/405—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from algae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6432—Eicosapentaenoic acids [EPA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6434—Docosahexenoic acids [DHA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/231,899 US6566583B1 (en) | 1997-06-04 | 1999-01-14 | Schizochytrium PKS genes |
PCT/US2000/000956 WO2000042195A2 (en) | 1999-01-14 | 2000-01-14 | Schizochytrium pks genes |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0008760A true BR0008760A (pt) | 2002-10-08 |
Family
ID=22871074
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0008760-2A BR0008760A (pt) | 1999-01-14 | 2000-01-14 | Genes pks da schizochytrium |
Country Status (10)
Country | Link |
---|---|
US (6) | US6566583B1 (pt) |
EP (4) | EP2333071A1 (pt) |
JP (3) | JP2002534123A (pt) |
BR (1) | BR0008760A (pt) |
CA (1) | CA2359629C (pt) |
ES (1) | ES2427017T3 (pt) |
HK (2) | HK1041292A1 (pt) |
IL (4) | IL144269A0 (pt) |
MX (1) | MX252154B (pt) |
WO (1) | WO2000042195A2 (pt) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6566583B1 (en) * | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
US7271315B2 (en) * | 1999-01-14 | 2007-09-18 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
US7217856B2 (en) * | 1999-01-14 | 2007-05-15 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
US7247461B2 (en) | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
US20070244192A1 (en) * | 1999-01-14 | 2007-10-18 | Martek Biosciences Corporation | Plant seed oils containing polyunsaturated fatty acids |
US7211418B2 (en) * | 1999-01-14 | 2007-05-01 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
US8003772B2 (en) * | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
RU2336307C2 (ru) | 2000-01-19 | 2008-10-20 | Мартек Биосайнсис Корпорейшн | Способ получения липидов (варианты) и липиды, полученные этим способом |
KR101293135B1 (ko) | 2000-01-28 | 2013-09-12 | 디에스엠 아이피 어셋츠 비.브이. | 발효기 내에서 진핵 미생물의 고밀도 배양에 의한 고도불포화 지방산을 함유하는 지질의 증진된 생산 방법 |
TWI337619B (en) * | 2001-04-16 | 2011-02-21 | Martek Biosciences Corp | Pufa polyketide synthase systems and uses thereof |
AU2003238264B2 (en) | 2002-06-18 | 2009-05-21 | Dsm Ip Assets B.V. | Stable emulsions of oils in aqueous solutions and methods for producing same |
BR0317304A (pt) | 2002-12-19 | 2005-11-08 | Univ Bristol | Processo para a produção de compostos, sequência de ácido nucleico isolada, sequência de aminoácidos, construção gênica, vetor, e, organismo |
ATE517984T1 (de) | 2003-02-27 | 2011-08-15 | Basf Plant Science Gmbh | Verfahren zur herstellung mehrfach ungesättigter fettsäuren |
US20070082008A1 (en) * | 2003-03-07 | 2007-04-12 | Advanced Bionutrition Corporation | Feed formulation for terrestrial and aquatic animals |
EP1623008B1 (en) * | 2003-03-26 | 2014-07-30 | DSM IP Assets B.V. | Pufa polyketide synthase systems and uses thereof |
WO2004087902A2 (de) | 2003-03-31 | 2004-10-14 | University Of Bristol | Neue pflanzliche acyltransferasen spezifisch für langkettige mehrfach ungesättigte fettsäuren |
US7208590B2 (en) * | 2003-07-15 | 2007-04-24 | Abbott Laboratories | Genes involved in polyketide synthase pathways and uses thereof |
US7646815B2 (en) * | 2003-07-15 | 2010-01-12 | Lsi Corporation | Intra estimation chroma mode 0 sub-block dependent prediction |
DE102004017370A1 (de) * | 2004-04-08 | 2005-10-27 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | PUFA-PKS Gene aus Ulkenia |
DE102004017369A1 (de) * | 2004-04-08 | 2005-11-03 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Screeningverfahren zur Identifizierung von PUFA-PKS in Proben |
ES2529572T3 (es) | 2004-04-22 | 2015-02-23 | Commonwealth Scientific And Industrial Research Organisation | Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes |
CA2884237C (en) | 2004-04-22 | 2020-09-08 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
CA2598792A1 (en) * | 2005-03-02 | 2006-09-08 | Metanomics Gmbh | Process for the production of fine chemicals |
CA2611324C (en) | 2005-06-07 | 2017-02-14 | Ocean Nutrition Canada Limited | Eukaryotic microorganisms for producing lipids and antioxidants |
JP4819888B2 (ja) | 2005-07-01 | 2011-11-24 | マーテック バイオサイエンシーズ コーポレーション | 多価不飽和脂肪酸含有油産物ならびにその使用および産生 |
JP4943678B2 (ja) * | 2005-08-01 | 2012-05-30 | 国立大学法人北海道大学 | 細胞の脂肪酸組成を改変する方法およびその利用 |
DK1965658T3 (en) | 2005-11-18 | 2019-01-21 | Commw Scient Ind Res Org | FEATURES FOR AQUACULTURE INCLUDING STEARIDONIC ACID |
KR101506347B1 (ko) * | 2006-03-15 | 2015-03-26 | 디에스엠 아이피 어셋츠 비.브이. | 다불포화 지방산을 함유하는 식물 종자 오일 |
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ES2668640T5 (es) | 2006-06-22 | 2022-05-12 | Dsm Ip Assets Bv | Composiciones de compuestos lábiles encapsulados y métodos para preparar las mismas |
WO2008129358A2 (en) * | 2006-08-01 | 2008-10-30 | Ocean Nutrition Canada Ltd. | Oil producing microbes and methods of modification thereof |
AU2007289233A1 (en) | 2006-08-29 | 2008-03-06 | Dsm Ip Assets B.V. | Use of DPA(n-6) oils in infant formula |
WO2008025068A1 (en) | 2006-08-29 | 2008-03-06 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of fatty acids |
EP2126042A4 (en) * | 2007-01-12 | 2010-08-04 | Univ Colorado Regents | COMPOSITIONS AND METHODS FOR IMPROVING THE PRODUCTION TOLERANCE OF ORGANIC CHEMICALS FROM MICROORGANISMS |
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WO2009017678A2 (en) | 2007-07-26 | 2009-02-05 | Pacific Biosciences Of California, Inc. | Molecular redundant sequencing |
US8048624B1 (en) | 2007-12-04 | 2011-11-01 | Opx Biotechnologies, Inc. | Compositions and methods for 3-hydroxypropionate bio-production from biomass |
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CA2743880C (en) | 2008-11-18 | 2020-08-18 | James Robertson Petrie | Recombinant cells comprising exogenous a5 elongase and methods for producing docosapentaenoic acid |
WO2010108114A2 (en) | 2009-03-19 | 2010-09-23 | Martek Biosciences Corporation | Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof |
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PL3082793T3 (pl) | 2013-12-20 | 2020-10-05 | Dsm Ip Assets B.V. | Sposoby otrzymywania oleju drobnoustrojowego z komórek drobnoustrojowych |
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KR102527795B1 (ko) | 2014-06-27 | 2023-05-02 | 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 | 도코사펜타에노산을 포함하는 지질 |
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EP2333072A1 (en) | 2011-06-15 |
IL224871A (en) | 2017-11-30 |
CA2359629C (en) | 2015-02-24 |
HK1159166A1 (en) | 2012-07-27 |
EP1147197A2 (en) | 2001-10-24 |
HK1041292A1 (zh) | 2002-07-05 |
WO2000042195A3 (en) | 2000-09-28 |
IL144269A0 (en) | 2002-05-23 |
IL188590A (en) | 2013-06-27 |
MX252154B (es) | 2007-12-04 |
JP2008099697A (ja) | 2008-05-01 |
EP2333072B1 (en) | 2013-06-19 |
MXPA01007153A (es) | 2003-07-21 |
CA2359629A1 (en) | 2000-07-20 |
JP2002534123A (ja) | 2002-10-15 |
US7214853B2 (en) | 2007-05-08 |
US8829274B2 (en) | 2014-09-09 |
EP2333073A1 (en) | 2011-06-15 |
IL144269A (en) | 2010-04-15 |
US7897844B2 (en) | 2011-03-01 |
US20090098622A1 (en) | 2009-04-16 |
IL188590A0 (en) | 2008-04-13 |
WO2000042195A2 (en) | 2000-07-20 |
US20140053299A1 (en) | 2014-02-20 |
WO2000042195B1 (en) | 2000-11-09 |
US20110250342A1 (en) | 2011-10-13 |
JP2010252811A (ja) | 2010-11-11 |
US20030101486A1 (en) | 2003-05-29 |
ES2427017T3 (es) | 2013-10-28 |
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