BG64272B1 - 'Ъ''АВИ, 'ЪДЪРЖА(tm)И ПРО'ИВОГЪБИ-НО 'Р...Д''ВО И А-...'А'...Н Б""...Р - Google Patents

'Ъ''АВИ, 'ЪДЪРЖА(tm)И ПРО'ИВОГЪБИ-НО 'Р...Д''ВО И А-...'А'...Н Б""...Р Download PDF

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Publication number
BG64272B1
BG64272B1 BG102857A BG10285798A BG64272B1 BG 64272 B1 BG64272 B1 BG 64272B1 BG 102857 A BG102857 A BG 102857A BG 10285798 A BG10285798 A BG 10285798A BG 64272 B1 BG64272 B1 BG 64272B1
Authority
BG
Bulgaria
Prior art keywords
compound
pharmaceutically acceptable
composition according
acetate buffer
water
Prior art date
Application number
BG102857A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG102857A (en
Inventor
Maneesh J. Nerurkar
William A. Nunke
Michael J. Kaufman
Original Assignee
Merck & Co.,Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26309400&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG64272(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9611006.9A external-priority patent/GB9611006D0/en
Application filed by Merck & Co.,Inc. filed Critical Merck & Co.,Inc.
Publication of BG102857A publication Critical patent/BG102857A/xx
Publication of BG64272B1 publication Critical patent/BG64272B1/bg

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
BG102857A 1996-04-19 1998-10-19 'Ъ''АВИ, 'ЪДЪРЖА(tm)И ПРО'ИВОГЪБИ-НО 'Р...Д''ВО И А-...'А'...Н Б""...Р BG64272B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1563896P 1996-04-19 1996-04-19
GBGB9611006.9A GB9611006D0 (en) 1996-05-24 1996-05-24 Antifungal compositions
PCT/US1997/006284 WO1997039763A1 (en) 1996-04-19 1997-04-15 Compositions comprising antifungal agent and acetate buffer

Publications (2)

Publication Number Publication Date
BG102857A BG102857A (en) 1999-09-30
BG64272B1 true BG64272B1 (bg) 2004-08-31

Family

ID=26309400

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102857A BG64272B1 (bg) 1996-04-19 1998-10-19 'Ъ''АВИ, 'ЪДЪРЖА(tm)И ПРО'ИВОГЪБИ-НО 'Р...Д''ВО И А-...'А'...Н Б""...Р

Country Status (36)

Country Link
EP (1) EP0904098B1 (xx)
JP (1) JP3258672B2 (xx)
CN (1) CN1132624C (xx)
AR (1) AR006598A1 (xx)
AT (1) ATE241999T1 (xx)
AU (1) AU706250B2 (xx)
BG (1) BG64272B1 (xx)
BR (2) BR9708706B8 (xx)
CA (1) CA2251928C (xx)
CO (1) CO4940486A1 (xx)
CY (1) CY2374B1 (xx)
CZ (1) CZ289361B6 (xx)
DE (1) DE69722615T2 (xx)
DK (1) DK0904098T3 (xx)
DZ (1) DZ2205A1 (xx)
EA (1) EA001386B1 (xx)
EE (1) EE04265B1 (xx)
ES (1) ES2198569T3 (xx)
HK (1) HK1020873A1 (xx)
HR (1) HRP970201B1 (xx)
HU (1) HU228296B1 (xx)
ID (1) ID16643A (xx)
IL (1) IL126479A (xx)
IS (1) IS2159B (xx)
MY (1) MY126305A (xx)
NO (1) NO321954B1 (xx)
NZ (1) NZ332156A (xx)
PE (1) PE63998A1 (xx)
PL (1) PL187294B1 (xx)
PT (1) PT904098E (xx)
RS (1) RS49566B (xx)
SA (1) SA97180104B1 (xx)
SK (1) SK281969B6 (xx)
TR (1) TR199802102T2 (xx)
UA (1) UA55409C2 (xx)
WO (1) WO1997039763A1 (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1156782B1 (en) * 1999-03-03 2005-05-04 Eli Lilly And Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
CN101516387B (zh) * 2006-07-26 2014-06-04 桑多斯股份公司 卡泊芬净制剂
BRPI0715113A2 (pt) * 2006-07-26 2013-06-04 Sandoz Ag Sandoz Sa Sandoz Ltd formulaÇço de caspofungina
JP5537425B2 (ja) * 2007-06-26 2014-07-02 メルク・シャープ・アンド・ドーム・コーポレーション 凍結乾燥抗真菌組成物
US8048853B2 (en) 2008-06-13 2011-11-01 Xellia Pharmaceuticals Aps Process for preparing pharmaceutical compound and intermediates thereof
US20100256074A1 (en) * 2008-06-25 2010-10-07 Chaim Eidelman Processes for preparing high purity aza cyclohexapeptides
WO2010108637A1 (en) * 2009-03-27 2010-09-30 Axellia Pharmaceuticals Aps Crystalline compound
CN102219832B (zh) * 2010-04-15 2013-08-21 上海天伟生物制药有限公司 一种氮杂环六肽或其盐的纯化方法
CN102367267B (zh) * 2010-11-10 2013-09-04 上海天伟生物制药有限公司 一种卡泊芬净的制备方法
CN102367268B (zh) * 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其用途
CN102367269B (zh) * 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其制备方法和用途
CN102614493B (zh) * 2011-01-31 2013-12-11 上海天伟生物制药有限公司 一种含有棘白菌素类抗真菌剂卡泊芬净的液体药用组合物
CN102488887B (zh) * 2011-01-31 2014-06-18 上海天伟生物制药有限公司 一种含有棘白菌素类抗真菌剂卡泊芬净的药用组合物及其制备方法和用途
CN102488888B (zh) * 2011-01-31 2014-07-30 上海天伟生物制药有限公司 一种含有棘白菌素类抗真菌剂的药用组合物及其制备方法和用途
CN102166186A (zh) * 2011-04-18 2011-08-31 深圳市健元医药科技有限公司 一种更加稳定的氮杂环己肽类制剂
CN102488889B (zh) * 2011-09-26 2014-01-22 上海天伟生物制药有限公司 一种低杂质含量的卡泊芬净制剂及其制备方法和用途
CN103315969B (zh) * 2011-09-26 2016-05-18 上海天伟生物制药有限公司 一种低杂质含量的卡泊芬净制剂及其制备方法和用途
CN103212059A (zh) * 2012-01-18 2013-07-24 江苏恒瑞医药股份有限公司 含有抗真菌药物和乳酸盐缓冲液的组合物
DK2827710T3 (da) * 2012-03-19 2020-02-03 Cidara Therapeutics Inc Doseringsskema for echinocandin-klasse-forbindelser
US9828411B2 (en) 2013-05-02 2017-11-28 Dsm Sinochem Pharmaceuticals Netherlands B.V. Method for isolating caspofungin
ES2694561T3 (es) 2015-02-23 2018-12-21 Selectchemie Ag Composición de anidulafungina
EP4268896A3 (en) 2016-03-16 2024-01-03 Cidara Therapeutics, Inc. Dosing regimens for treatment of fungal infections
CA3069423A1 (en) 2017-07-12 2019-01-17 Cidara Therapeutics, Inc. Formulations for the treatment of fungal infections
CN109721641B (zh) * 2017-10-31 2021-08-03 鲁南制药集团股份有限公司 一种卡泊芬净的合成方法
CN113801202A (zh) * 2020-06-15 2021-12-17 杭州中美华东制药有限公司 一种醋酸卡泊芬净杂质g的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1234383A (en) * 1982-03-17 1983-09-22 Inter-Yeda Ltd. Interferon stabilised with polyvinyl-pyrrolidone
EP0417193B1 (en) * 1988-05-27 1993-08-04 Centocor, Inc. Freeze-dried formulation for antibody products
US5939384A (en) * 1991-10-01 1999-08-17 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
DE4305225A1 (de) * 1993-02-19 1994-08-25 Asta Medica Ag Neues Herstellverfahren für Cetrorelix Lyophilisat
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
IL109350A (en) * 1993-05-12 2001-01-28 Genentech Inc Stable liquid preparations of gamma interferon

Also Published As

Publication number Publication date
AU2731197A (en) 1997-11-12
PL187294B1 (pl) 2004-06-30
NO321954B1 (no) 2006-07-31
CN1132624C (zh) 2003-12-31
ID16643A (id) 1997-10-23
NO984860L (no) 1998-12-18
CA2251928A1 (en) 1997-10-30
EA001386B1 (ru) 2001-02-26
EP0904098A1 (en) 1999-03-31
PT904098E (pt) 2003-09-30
CZ289361B6 (cs) 2002-01-16
NZ332156A (en) 2000-04-28
BG102857A (en) 1999-09-30
SK281969B6 (sk) 2001-09-11
SK144898A3 (en) 1999-05-07
RS49566B (sr) 2007-04-10
BR9708706A (pt) 1999-08-03
CA2251928C (en) 2003-06-17
BRPI9708706C8 (pt) 2021-01-05
MY126305A (en) 2006-09-29
EP0904098B1 (en) 2003-06-04
CY2374B1 (en) 2004-06-04
JPH11509555A (ja) 1999-08-24
ATE241999T1 (de) 2003-06-15
JP3258672B2 (ja) 2002-02-18
BR9708706B1 (pt) 2013-08-06
TR199802102T2 (xx) 1999-01-18
HUP9901586A2 (hu) 1999-08-30
IS4858A (is) 1998-10-02
CO4940486A1 (es) 2000-07-24
YU45098A (sh) 1999-07-28
SA97180104B1 (ar) 2006-02-08
CN1222082A (zh) 1999-07-07
NO984860D0 (no) 1998-10-16
EE04265B1 (et) 2004-04-15
DE69722615T2 (de) 2004-04-29
PL329442A1 (en) 1999-03-29
BR9708706B8 (pt) 2019-03-06
DE69722615D1 (de) 2003-07-10
EA199800938A1 (ru) 1999-04-29
HRP970201B1 (en) 2002-06-30
HK1020873A1 (en) 2000-05-26
CZ334798A3 (cs) 1999-06-16
WO1997039763A1 (en) 1997-10-30
EE9800345A (et) 1999-04-15
IS2159B (is) 2006-11-15
IL126479A (en) 2006-08-01
HU228296B1 (en) 2013-03-28
AR006598A1 (es) 1999-09-08
PE63998A1 (es) 1998-10-30
IL126479A0 (en) 1999-08-17
HUP9901586A3 (en) 2002-05-28
ES2198569T3 (es) 2004-02-01
HRP970201A2 (en) 1998-08-31
DK0904098T3 (da) 2003-09-15
UA55409C2 (uk) 2003-04-15
AU706250B2 (en) 1999-06-10
DZ2205A1 (fr) 2002-12-03

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