HUP9901586A2 - Antifungális szert és acetátpuffert tartalmazó készítmények és alkalmazásuk - Google Patents

Antifungális szert és acetátpuffert tartalmazó készítmények és alkalmazásuk

Info

Publication number
HUP9901586A2
HUP9901586A2 HU9901586A HUP9901586A HUP9901586A2 HU P9901586 A2 HUP9901586 A2 HU P9901586A2 HU 9901586 A HU9901586 A HU 9901586A HU P9901586 A HUP9901586 A HU P9901586A HU P9901586 A2 HUP9901586 A2 HU P9901586A2
Authority
HU
Hungary
Prior art keywords
medicinally
soluble
compositions
acetate buffer
antifungal agent
Prior art date
Application number
HU9901586A
Other languages
English (en)
Inventor
William A. Hunke
Michael J. Kaufman
Maneesh J. Nerurkar
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26309400&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9901586(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9611006.9A external-priority patent/GB9611006D0/en
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of HUP9901586A2 publication Critical patent/HUP9901586A2/hu
Publication of HUP9901586A3 publication Critical patent/HUP9901586A3/hu
Publication of HU228296B1 publication Critical patent/HU228296B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A találmány intravénásan adagőlható gyógyászati készítményrevőnatkőzik, amely a) gyógyászatilag hatásős mennyiségű (I) képletű vegyületet vagy annakgyógyászatilag elfőgadható sóját, b) a liőfilizátűm kialakításáhőz szükséges gyógyászatilag elfőgadhatómennyiségű segédanyagőt, példáűl térfőgatnövelő szert, és c) gyógyászatilag elfőgadható pH-érték beállításáhőz szükségesgyógyászatilag elfőgadható mennyiségű acetát pűffert tartalmaz. ŕ
HU9901586A 1996-04-19 1997-04-15 Compositions comprising antifungal agent and acetate buffer and their use HU228296B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1563896P 1996-04-19 1996-04-19
GBGB9611006.9A GB9611006D0 (en) 1996-05-24 1996-05-24 Antifungal compositions
PCT/US1997/006284 WO1997039763A1 (en) 1996-04-19 1997-04-15 Compositions comprising antifungal agent and acetate buffer

Publications (3)

Publication Number Publication Date
HUP9901586A2 true HUP9901586A2 (hu) 1999-08-30
HUP9901586A3 HUP9901586A3 (en) 2002-05-28
HU228296B1 HU228296B1 (en) 2013-03-28

Family

ID=26309400

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9901586A HU228296B1 (en) 1996-04-19 1997-04-15 Compositions comprising antifungal agent and acetate buffer and their use

Country Status (36)

Country Link
EP (1) EP0904098B1 (hu)
JP (1) JP3258672B2 (hu)
CN (1) CN1132624C (hu)
AR (1) AR006598A1 (hu)
AT (1) ATE241999T1 (hu)
AU (1) AU706250B2 (hu)
BG (1) BG64272B1 (hu)
BR (2) BR9708706B8 (hu)
CA (1) CA2251928C (hu)
CO (1) CO4940486A1 (hu)
CY (1) CY2374B1 (hu)
CZ (1) CZ289361B6 (hu)
DE (1) DE69722615T2 (hu)
DK (1) DK0904098T3 (hu)
DZ (1) DZ2205A1 (hu)
EA (1) EA001386B1 (hu)
EE (1) EE04265B1 (hu)
ES (1) ES2198569T3 (hu)
HK (1) HK1020873A1 (hu)
HR (1) HRP970201B1 (hu)
HU (1) HU228296B1 (hu)
ID (1) ID16643A (hu)
IL (1) IL126479A (hu)
IS (1) IS2159B (hu)
MY (1) MY126305A (hu)
NO (1) NO321954B1 (hu)
NZ (1) NZ332156A (hu)
PE (1) PE63998A1 (hu)
PL (1) PL187294B1 (hu)
PT (1) PT904098E (hu)
RS (1) RS49566B (hu)
SA (1) SA97180104B1 (hu)
SK (1) SK281969B6 (hu)
TR (1) TR199802102T2 (hu)
UA (1) UA55409C2 (hu)
WO (1) WO1997039763A1 (hu)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2433678T3 (es) * 1999-03-03 2013-12-12 Eli Lilly & Company Formulaciones farmacéuticas de equinocandina que contienen tensioactivos formadores de micelas
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
CN101516387B (zh) * 2006-07-26 2014-06-04 桑多斯股份公司 卡泊芬净制剂
US8232245B2 (en) * 2006-07-26 2012-07-31 Sandoz Ag Caspofungin formulations
WO2009002481A1 (en) 2007-06-26 2008-12-31 Merck & Co., Inc. Lyophilized anti-fungal composition
US8048853B2 (en) 2008-06-13 2011-11-01 Xellia Pharmaceuticals Aps Process for preparing pharmaceutical compound and intermediates thereof
EP2240507A2 (en) * 2008-06-25 2010-10-20 TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság Processes for preparing high purity aza cyclohexapeptides
WO2010108637A1 (en) * 2009-03-27 2010-09-30 Axellia Pharmaceuticals Aps Crystalline compound
CN102219832B (zh) * 2010-04-15 2013-08-21 上海天伟生物制药有限公司 一种氮杂环六肽或其盐的纯化方法
CN102367267B (zh) * 2010-11-10 2013-09-04 上海天伟生物制药有限公司 一种卡泊芬净的制备方法
CN102367268B (zh) * 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其用途
CN102367269B (zh) * 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其制备方法和用途
CN102488887B (zh) * 2011-01-31 2014-06-18 上海天伟生物制药有限公司 一种含有棘白菌素类抗真菌剂卡泊芬净的药用组合物及其制备方法和用途
CN102614493B (zh) * 2011-01-31 2013-12-11 上海天伟生物制药有限公司 一种含有棘白菌素类抗真菌剂卡泊芬净的液体药用组合物
CN102488888B (zh) * 2011-01-31 2014-07-30 上海天伟生物制药有限公司 一种含有棘白菌素类抗真菌剂的药用组合物及其制备方法和用途
CN102166186A (zh) * 2011-04-18 2011-08-31 深圳市健元医药科技有限公司 一种更加稳定的氮杂环己肽类制剂
CN102488886B (zh) * 2011-09-26 2014-03-26 上海天伟生物制药有限公司 一种低杂质含量的卡泊芬净制剂及其制备方法和用途
CN103386117B (zh) * 2011-09-26 2015-09-30 上海天伟生物制药有限公司 一种低杂质含量的卡泊芬净制剂及其制备方法和用途
CN103212059A (zh) * 2012-01-18 2013-07-24 江苏恒瑞医药股份有限公司 含有抗真菌药物和乳酸盐缓冲液的组合物
RU2639483C2 (ru) * 2012-03-19 2017-12-21 Сидара Терапьютикс, Инк. Режимы дозирования для соединений класса эхинокандинов
WO2014177483A1 (en) * 2013-05-02 2014-11-06 Dsm Sinochem Pharmaceuticals Netherlands B.V. Method for isolating caspofungin
PL3058958T3 (pl) 2015-02-23 2019-02-28 Selectchemie Ag Kompozycja anidulafunginy
CN109154603A (zh) 2016-03-16 2019-01-04 奇达拉治疗公司 用于治疗真菌感染的给药方案
JP2020529973A (ja) 2017-07-12 2020-10-15 シダラ セラピューティクス インコーポレーテッド 真菌感染症の処置のための組成物及び方法
CN109721641B (zh) * 2017-10-31 2021-08-03 鲁南制药集团股份有限公司 一种卡泊芬净的合成方法
CN113801202A (zh) * 2020-06-15 2021-12-17 杭州中美华东制药有限公司 一种醋酸卡泊芬净杂质g的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1234383A (en) * 1982-03-17 1983-09-22 Inter-Yeda Ltd. Interferon stabilised with polyvinyl-pyrrolidone
DE68908175T2 (de) * 1988-05-27 1994-03-03 Centocor Inc Gefriergetrocknete formulierung für antikörperprodukte.
US5939384A (en) * 1991-10-01 1999-08-17 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
DE4305225A1 (de) * 1993-02-19 1994-08-25 Asta Medica Ag Neues Herstellverfahren für Cetrorelix Lyophilisat
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
IL109350A (en) * 1993-05-12 2001-01-28 Genentech Inc Stable liquid preparations of gamma interferon

Also Published As

Publication number Publication date
ES2198569T3 (es) 2004-02-01
PE63998A1 (es) 1998-10-30
BG64272B1 (bg) 2004-08-31
DK0904098T3 (da) 2003-09-15
BR9708706A (pt) 1999-08-03
JPH11509555A (ja) 1999-08-24
SK144898A3 (en) 1999-05-07
NZ332156A (en) 2000-04-28
BG102857A (en) 1999-09-30
CN1222082A (zh) 1999-07-07
PL329442A1 (en) 1999-03-29
DE69722615D1 (de) 2003-07-10
SK281969B6 (sk) 2001-09-11
UA55409C2 (uk) 2003-04-15
YU45098A (sh) 1999-07-28
HU228296B1 (en) 2013-03-28
DZ2205A1 (fr) 2002-12-03
ID16643A (id) 1997-10-23
NO984860D0 (no) 1998-10-16
NO321954B1 (no) 2006-07-31
PL187294B1 (pl) 2004-06-30
AR006598A1 (es) 1999-09-08
IL126479A0 (en) 1999-08-17
TR199802102T2 (xx) 1999-01-18
CZ334798A3 (cs) 1999-06-16
EP0904098A1 (en) 1999-03-31
AU2731197A (en) 1997-11-12
DE69722615T2 (de) 2004-04-29
BR9708706B1 (pt) 2013-08-06
CA2251928C (en) 2003-06-17
CN1132624C (zh) 2003-12-31
RS49566B (sr) 2007-04-10
JP3258672B2 (ja) 2002-02-18
AU706250B2 (en) 1999-06-10
CA2251928A1 (en) 1997-10-30
IS2159B (is) 2006-11-15
EE04265B1 (et) 2004-04-15
IS4858A (is) 1998-10-02
PT904098E (pt) 2003-09-30
HUP9901586A3 (en) 2002-05-28
EA199800938A1 (ru) 1999-04-29
EE9800345A (et) 1999-04-15
HRP970201B1 (en) 2002-06-30
SA97180104B1 (ar) 2006-02-08
HK1020873A1 (en) 2000-05-26
ATE241999T1 (de) 2003-06-15
MY126305A (en) 2006-09-29
BR9708706B8 (pt) 2019-03-06
EP0904098B1 (en) 2003-06-04
CY2374B1 (en) 2004-06-04
NO984860L (no) 1998-12-18
BRPI9708706C8 (pt) 2021-01-05
IL126479A (en) 2006-08-01
EA001386B1 (ru) 2001-02-26
HRP970201A2 (en) 1998-08-31
CZ289361B6 (cs) 2002-01-16
CO4940486A1 (es) 2000-07-24
WO1997039763A1 (en) 1997-10-30

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Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: MERCK SHARP & DOHME CORP., US

Free format text: FORMER OWNER(S): MERCK & CO., INC., US

GB9A Succession in title

Owner name: MERCK SHARP & DOHME CORP., US

Free format text: FORMER OWNER(S): MERCK SHARP & DOHME CORP., US; MERCK & CO., INC., US; SCHERING CORPORATION, US

HC9A Change of name, address

Owner name: MERCK SHARP & DOHME CORP., US

Free format text: FORMER OWNER(S): MERCK SHARP & DOHME CORP., US; MERCK & CO., INC., US; SCHERING CORPORATION, US