BG63895B1 - Метод за количествен синтез на 3-[l-пироглутамил]-l- тиазолидин-4-карбоксилна киселина и на нейни производни - Google Patents

Метод за количествен синтез на 3-[l-пироглутамил]-l- тиазолидин-4-карбоксилна киселина и на нейни производни Download PDF

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Publication number
BG63895B1
BG63895B1 BG101310A BG10131097A BG63895B1 BG 63895 B1 BG63895 B1 BG 63895B1 BG 101310 A BG101310 A BG 101310A BG 10131097 A BG10131097 A BG 10131097A BG 63895 B1 BG63895 B1 BG 63895B1
Authority
BG
Bulgaria
Prior art keywords
formula
halide
carboxylic acid
pyroglutamyl
thiazolidine
Prior art date
Application number
BG101310A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG101310A (en
Inventor
Stefano Poli
Ambrogio Magni
Gianettore Bocchiola
Original Assignee
Poli Industria Chimica S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poli Industria Chimica S.P.A. filed Critical Poli Industria Chimica S.P.A.
Publication of BG101310A publication Critical patent/BG101310A/xx
Publication of BG63895B1 publication Critical patent/BG63895B1/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Pyrrole Compounds (AREA)
BG101310A 1994-09-27 1997-03-11 Метод за количествен синтез на 3-[l-пироглутамил]-l- тиазолидин-4-карбоксилна киселина и на нейни производни BG63895B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI941955A IT1270017B (it) 1994-09-27 1994-09-27 "sintesi quantitativa dell'acido 3-(l-piroglutamil)-l-tiazolidin-4- carbossilico e suoi derivati"
PCT/EP1995/003720 WO1996010036A1 (en) 1994-09-27 1995-09-21 A process for the quantitative synthesis of 3-(l-pyroglutamyl)-l-thiazolidine-4-carboxylic acid and derivatives thereof

Publications (2)

Publication Number Publication Date
BG101310A BG101310A (en) 1997-12-30
BG63895B1 true BG63895B1 (bg) 2003-05-30

Family

ID=11369599

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101310A BG63895B1 (bg) 1994-09-27 1997-03-11 Метод за количествен синтез на 3-[l-пироглутамил]-l- тиазолидин-4-карбоксилна киселина и на нейни производни

Country Status (10)

Country Link
CN (1) CN1143863C (it)
BG (1) BG63895B1 (it)
BR (1) BR9509087A (it)
CO (1) CO4480030A1 (it)
CZ (1) CZ91597A3 (it)
IT (1) IT1270017B (it)
PL (1) PL181824B1 (it)
RO (1) RO115957B1 (it)
SK (1) SK40097A3 (it)
WO (1) WO1996010036A1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108088936B (zh) * 2017-12-08 2020-05-22 常州寅盛药业有限公司 制备匹多莫德乙酯所得杂质及其质量检测方法
CN108715598A (zh) * 2018-06-13 2018-10-30 峨眉山宏昇药业股份有限公司 一种匹多莫德的制备方法
CN117088939A (zh) * 2022-05-11 2023-11-21 江苏吴中医药集团有限公司 一种匹多莫德的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1202426B (it) * 1987-01-26 1989-02-09 Poli Ind Chimica Spa Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono
IT1239029B (it) * 1989-10-12 1993-09-20 Poli Ind Chimica Spa Processo per la preparazione dell'acido 3-(l-piroglutamil)-l- tiazolidin-4-carbossilico e suoi derivati.

Also Published As

Publication number Publication date
SK40097A3 (en) 1997-09-10
BG101310A (en) 1997-12-30
CO4480030A1 (es) 1997-07-09
PL319380A1 (en) 1997-08-04
WO1996010036A1 (en) 1996-04-04
RO115957B1 (ro) 2000-08-30
BR9509087A (pt) 1998-07-21
CZ91597A3 (en) 1997-09-17
ITMI941955A1 (it) 1996-03-27
CN1143863C (zh) 2004-03-31
CN1158620A (zh) 1997-09-03
ITMI941955A0 (it) 1994-09-27
PL181824B1 (pl) 2001-09-28
IT1270017B (it) 1997-04-16

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