BG63122B1 - Compounds and methods for cancer treatment - Google Patents
Compounds and methods for cancer treatmentInfo
- Publication number
- BG63122B1 BG63122B1 BG101284A BG10128497A BG63122B1 BG 63122 B1 BG63122 B1 BG 63122B1 BG 101284 A BG101284 A BG 101284A BG 10128497 A BG10128497 A BG 10128497A BG 63122 B1 BG63122 B1 BG 63122B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- compounds
- methods
- cancer treatment
- treatment
- citosyne
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/301,298 US5817667A (en) | 1991-04-17 | 1994-09-06 | Compounds and methods for the treatment of cancer |
US39063395A | 1995-02-17 | 1995-02-17 | |
PCT/US1995/011464 WO1996007413A1 (en) | 1994-09-06 | 1995-09-05 | Compounds and methods for the treatment of cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
BG101284A BG101284A (en) | 1998-03-31 |
BG63122B1 true BG63122B1 (en) | 2001-04-30 |
Family
ID=26972285
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG101284A BG63122B1 (en) | 1994-09-06 | 1997-03-05 | Compounds and methods for cancer treatment |
Country Status (31)
Country | Link |
---|---|
US (3) | US6063787A (ja) |
EP (2) | EP1468687A1 (ja) |
JP (1) | JP3979662B2 (ja) |
KR (1) | KR100374477B1 (ja) |
CN (3) | CN1827108A (ja) |
AP (1) | AP783A (ja) |
AT (1) | ATE267015T1 (ja) |
AU (1) | AU704977B2 (ja) |
BG (1) | BG63122B1 (ja) |
BR (1) | BR9508886A (ja) |
CA (1) | CA2199117C (ja) |
CZ (1) | CZ297873B6 (ja) |
DE (1) | DE69533066T2 (ja) |
DK (1) | DK0781136T3 (ja) |
ES (1) | ES2219666T3 (ja) |
FI (1) | FI970918A (ja) |
HU (1) | HUT77172A (ja) |
IL (1) | IL115156A (ja) |
IS (1) | IS2011B (ja) |
MY (1) | MY121548A (ja) |
NO (1) | NO313268B1 (ja) |
NZ (1) | NZ335013A (ja) |
OA (1) | OA10473A (ja) |
PL (2) | PL189288B1 (ja) |
PT (1) | PT781136E (ja) |
RO (1) | RO118748B1 (ja) |
RU (1) | RU2168995C2 (ja) |
SI (1) | SI0781136T1 (ja) |
SK (1) | SK284564B6 (ja) |
WO (1) | WO1996007413A1 (ja) |
ZA (1) | ZA957483B (ja) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
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US6903224B2 (en) | 1988-04-11 | 2005-06-07 | Biochem Pharma Inc. | Substituted 1,3-oxathiolanes |
US6069252A (en) * | 1990-02-01 | 2000-05-30 | Emory University | Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers |
IL115156A (en) * | 1994-09-06 | 2000-07-16 | Univ Georgia | Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines |
US6022876A (en) * | 1996-11-15 | 2000-02-08 | Yale University | L-β-dioxolane uridine analogs and methods for treating and preventing Epstein-Barr virus infections |
JP2001512830A (ja) | 1997-08-08 | 2001-08-28 | ニューバイオティックス インコーポレイテッド | 生物療法耐性および化学療法耐性を克服するための方法および組成物 |
US7462605B2 (en) | 1998-01-23 | 2008-12-09 | Celmed Oncology (Usa), Inc. | Phosphoramidate compounds and methods of use |
IL137164A0 (en) | 1998-01-23 | 2001-07-24 | Newbiotics Inc | Enzyme catalyzed therapeutic agents |
ES2276515T3 (es) | 1998-02-25 | 2007-06-16 | Emory University | 2'-fluoronucleosidos. |
ATE442151T1 (de) | 1999-03-29 | 2009-09-15 | Shire Canada Inc | Verwendung von cytidinderivaten zur behandlung von leukämie |
AU2004201676B2 (en) * | 1999-03-29 | 2006-03-09 | University Of Georgia Research Foundation, Inc. | Methods of treating leukemia |
US6653318B1 (en) | 1999-07-21 | 2003-11-25 | Yale University | 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use |
US6683061B1 (en) | 1999-07-22 | 2004-01-27 | Newbiotics, Inc. | Enzyme catalyzed therapeutic activation |
EP1214074B1 (en) | 1999-09-24 | 2004-06-16 | Shire Biochem Inc. | Dioxolane nucleoside analogs for the treatment or prevention of viral infection |
CA2389745C (en) | 1999-11-04 | 2010-03-23 | Shire Biochem Inc. | Method for the treatment or prevention of flaviviridae viral infection using nucleoside analogues |
EP1634888A3 (en) | 1999-11-12 | 2007-11-21 | Pharmasset, Inc. | Synthesis of 2'-deoxy-L-nucleosides |
CA2425359A1 (en) * | 2000-10-13 | 2002-04-18 | Shire Biochem Inc. | Dioxolane analogs for improved inter-cellular delivery |
AU2002241911B9 (en) | 2001-01-19 | 2007-01-25 | Celmed Oncology (Usa), Inc. | Methods to treat autoimmune and inflammatory conditions |
NZ528394A (en) | 2001-03-23 | 2005-06-24 | Shire Biochem Inc | Pharmaceutical combinations for the treatment of cancer comprising dioxolane analogues and nuceloside analogues and/or chemotherapeutic agents |
CN1744902B (zh) * | 2001-03-23 | 2010-05-26 | 希拉加拿大股份有限公司 | 治疗癌症的药物组合 |
US20030027799A1 (en) * | 2001-03-30 | 2003-02-06 | Shire Biochem Inc. | Methods of treating cancer using a combination of drugs |
EP1441733A1 (en) * | 2001-11-02 | 2004-08-04 | Shire Biochem Inc. | Pharmaceutical compositions for the treatment of leukemia comprising dioxolane nucleosides analogs |
MXPA04004532A (es) * | 2001-11-19 | 2004-08-11 | Medigene Ag | Medicamento para el tratamiento de enfermedades tumorales y virales de la piel. |
MXPA04002365A (es) | 2002-06-21 | 2004-11-22 | Lg Electronics Inc | Medio de grabacion que tiene estructura de datos para manejar la reproduccion de datos de video grabados en el mismo. |
AU2003228113B2 (en) | 2002-06-21 | 2009-02-26 | Lg Electronics Inc. | Recording medium having data structure for managing reproduction of video data recorded thereon |
JP4418747B2 (ja) | 2002-06-24 | 2010-02-24 | エルジー エレクトロニクス インコーポレイティド | ビデオデータの再生を管理するためのナビゲーション制御情報が含まれたデータ構造を有する記録媒体と、それによる記録と再生の方法及び装置 |
KR20040000290A (ko) | 2002-06-24 | 2004-01-03 | 엘지전자 주식회사 | 고밀도 광디스크의 멀티 경로 데이터 스트림 관리방법 |
WO2004003908A1 (en) | 2002-06-28 | 2004-01-08 | Lg Electronics Inc. | Recording medium having data structure for managing recording and reproduction of multiple path data recorded thereon and recording and reproducing methods and apparatus |
JP4431043B2 (ja) | 2002-10-14 | 2010-03-10 | エルジー エレクトロニクス インコーポレイティド | 記録された複数のオーディオストリームの再生を管理するためのデータ構造を有する光ディスク、それによる記録及び再生方法及び装置 |
ATE547792T1 (de) | 2002-10-15 | 2012-03-15 | Lg Electronics Inc | Aufzeichnungsmedium mit einer datenstruktur zur verwaltung der wiedergabe mehrerer darauf aufgezeichneter grafikströme und aufzeichnungs- und wiedergabeverfahren und vorrichtungen |
US7720356B2 (en) | 2002-11-12 | 2010-05-18 | Lg Electronics Inc | Recording medium having data structure for managing reproduction of multiple reproduction path video data recorded thereon and recording and reproducing methods and apparatuses |
US7664372B2 (en) | 2002-11-20 | 2010-02-16 | Lg Electronics Inc. | Recording medium having data structure for managing reproduction of multiple component data recorded thereon and recording and reproducing methods and apparatuses |
US7693394B2 (en) | 2003-02-26 | 2010-04-06 | Lg Electronics Inc. | Recording medium having data structure for managing reproduction of data streams recorded thereon and recording and reproducing methods and apparatuses |
US7809775B2 (en) | 2003-02-27 | 2010-10-05 | Lg Electronics, Inc. | Recording medium having data structure for managing playback control recorded thereon and recording and reproducing methods and apparatuses |
WO2004077417A1 (en) | 2003-02-28 | 2004-09-10 | Lg Electronics Inc. | Recording medium having data structure for managing random/shuffle reproduction of video data recorded thereon and recording and reproducing methods and apparatuses |
US7620301B2 (en) | 2003-04-04 | 2009-11-17 | Lg Electronics Inc. | System and method for resuming playback |
WO2005037300A1 (en) | 2003-10-09 | 2005-04-28 | Medigene Ag | The use of a polyphenol for the treatment of a cancerous or pre-cancerous lesion of the skin |
BRPI0613796A2 (pt) * | 2005-06-07 | 2011-02-15 | Univ Yale | composicões farmacêuticas e seus usos, e métodos de tratamento de cáncer e outras condições ou estados patológicos, por meio do uso de clevudina (lfmau) e telbivudina (ldt) |
US7951788B2 (en) * | 2005-12-02 | 2011-05-31 | Yale University | Method of treating cancer and other conditions or disease states using L-cytosine nucleoside analogs |
NO324263B1 (no) * | 2005-12-08 | 2007-09-17 | Clavis Pharma Asa | Kjemiske forbindelser, anvendelse derav ved behandling av kreft, samt farmasoytiske preparater som omfatter slike forbindelser |
CA2662147A1 (en) * | 2006-09-01 | 2008-03-13 | University Of Georgia Research Foundation, Inc. | L-oddc prodrugs for cancer |
CN103720693A (zh) * | 2011-11-15 | 2014-04-16 | 张始状 | 人体五种正常碱基在制备治疗肿瘤药物中的应用 |
CN102406649A (zh) * | 2011-11-15 | 2012-04-11 | 张始状 | 人体五种正常碱基在制备治疗肿瘤药物中的应用 |
SG10201609131YA (en) | 2016-11-01 | 2018-06-28 | Xylonix Ip Holdings Pte Ltd | Zinc-pga compositions and methods for treating cancer |
JP7110203B2 (ja) * | 2016-12-28 | 2022-08-01 | トランジェーヌ | 腫瘍溶解性ウイルスおよび治療用分子 |
SG10201708886RA (en) * | 2017-10-30 | 2019-05-30 | Xylonix Ip Holdings Pte Ltd | α-PGA-ZINC COMPOSITIONS AND METHODS FOR TREATING CANCER |
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JPS5668674A (en) * | 1979-11-08 | 1981-06-09 | Shionogi & Co Ltd | 5-fluorouracil derivative |
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US4879277A (en) * | 1985-08-26 | 1989-11-07 | The United States Of America As Represented By The Department Of Health And Human Services | Antiviral compositions and methods |
ATE190064T1 (de) * | 1985-09-17 | 2000-03-15 | Wellcome Found | Kombination therapeutische nukleoside mit weiteren therapeutisch wirksamen komponenten. |
IN164556B (ja) * | 1986-03-06 | 1989-04-08 | Takeda Chemical Industries Ltd | |
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GB9104740D0 (en) * | 1991-03-06 | 1991-04-17 | Wellcome Found | Antiviral nucleoside combination |
US5817667A (en) * | 1991-04-17 | 1998-10-06 | University Of Georgia Research Foudation | Compounds and methods for the treatment of cancer |
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-
1995
- 1995-09-04 IL IL11515695A patent/IL115156A/xx not_active IP Right Cessation
- 1995-09-05 HU HU9701687A patent/HUT77172A/hu unknown
- 1995-09-05 ES ES95933071T patent/ES2219666T3/es not_active Expired - Lifetime
- 1995-09-05 PT PT95933071T patent/PT781136E/pt unknown
- 1995-09-05 DE DE69533066T patent/DE69533066T2/de not_active Expired - Lifetime
- 1995-09-05 AU AU35862/95A patent/AU704977B2/en not_active Ceased
- 1995-09-05 EP EP04003357A patent/EP1468687A1/en not_active Withdrawn
- 1995-09-05 EP EP95933071A patent/EP0781136B1/en not_active Expired - Lifetime
- 1995-09-05 WO PCT/US1995/011464 patent/WO1996007413A1/en active IP Right Grant
- 1995-09-05 US US08/809,007 patent/US6063787A/en not_active Expired - Fee Related
- 1995-09-05 CN CNA2006100549917A patent/CN1827108A/zh active Pending
- 1995-09-05 BR BR9508886A patent/BR9508886A/pt not_active Application Discontinuation
- 1995-09-05 CZ CZ0063397A patent/CZ297873B6/cs not_active IP Right Cessation
- 1995-09-05 AT AT95933071T patent/ATE267015T1/de not_active IP Right Cessation
- 1995-09-05 SI SI9530703T patent/SI0781136T1/xx unknown
- 1995-09-05 RO RO97-00419A patent/RO118748B1/ro unknown
- 1995-09-05 AP APAP/P/1997/000939A patent/AP783A/en active
- 1995-09-05 SK SK281-97A patent/SK284564B6/sk not_active IP Right Cessation
- 1995-09-05 KR KR1019970701464A patent/KR100374477B1/ko not_active IP Right Cessation
- 1995-09-05 JP JP50970596A patent/JP3979662B2/ja not_active Expired - Lifetime
- 1995-09-05 RU RU97105381/04A patent/RU2168995C2/ru not_active IP Right Cessation
- 1995-09-05 CA CA002199117A patent/CA2199117C/en not_active Expired - Fee Related
- 1995-09-05 CN CN95195621A patent/CN1111409C/zh not_active Expired - Lifetime
- 1995-09-05 PL PL95358979A patent/PL189288B1/pl not_active IP Right Cessation
- 1995-09-05 PL PL95318971A patent/PL188359B1/pl not_active IP Right Cessation
- 1995-09-05 DK DK95933071T patent/DK0781136T3/da active
- 1995-09-06 ZA ZA957483A patent/ZA957483B/xx unknown
- 1995-09-06 MY MYPI95002637A patent/MY121548A/en unknown
-
1997
- 1997-03-03 OA OA60972A patent/OA10473A/en unknown
- 1997-03-04 IS IS4434A patent/IS2011B/is unknown
- 1997-03-04 FI FI970918A patent/FI970918A/fi unknown
- 1997-03-05 NO NO19971015A patent/NO313268B1/no not_active IP Right Cessation
- 1997-03-05 BG BG101284A patent/BG63122B1/xx unknown
-
1999
- 1999-04-01 NZ NZ335013A patent/NZ335013A/xx not_active IP Right Cessation
-
2003
- 2003-04-18 CN CNB031106706A patent/CN1251680C/zh not_active Expired - Lifetime
- 2003-08-22 US US10/646,980 patent/US7262213B2/en not_active Expired - Lifetime
-
2007
- 2007-03-05 US US11/713,975 patent/US8076347B2/en not_active Expired - Lifetime
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