ZA957483B - Compounds and methods for the treatment of cancer - Google Patents

Compounds and methods for the treatment of cancer

Info

Publication number
ZA957483B
ZA957483B ZA957483A ZA957483A ZA957483B ZA 957483 B ZA957483 B ZA 957483B ZA 957483 A ZA957483 A ZA 957483A ZA 957483 A ZA957483 A ZA 957483A ZA 957483 B ZA957483 B ZA 957483B
Authority
ZA
South Africa
Prior art keywords
cancer
compounds
treatment
methods
Prior art date
Application number
ZA957483A
Other languages
English (en)
Inventor
Chung K Chu
Yung-Chi Cheng
Original Assignee
Univ Georgia Res Found
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/301,298 external-priority patent/US5817667A/en
Application filed by Univ Georgia Res Found, Univ Yale filed Critical Univ Georgia Res Found
Publication of ZA957483B publication Critical patent/ZA957483B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA957483A 1994-09-06 1995-09-06 Compounds and methods for the treatment of cancer ZA957483B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/301,298 US5817667A (en) 1991-04-17 1994-09-06 Compounds and methods for the treatment of cancer
US39063395A 1995-02-17 1995-02-17

Publications (1)

Publication Number Publication Date
ZA957483B true ZA957483B (en) 1997-06-06

Family

ID=26972285

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA957483A ZA957483B (en) 1994-09-06 1995-09-06 Compounds and methods for the treatment of cancer

Country Status (31)

Country Link
US (3) US6063787A (ja)
EP (2) EP0781136B1 (ja)
JP (1) JP3979662B2 (ja)
KR (1) KR100374477B1 (ja)
CN (3) CN1827108A (ja)
AP (1) AP783A (ja)
AT (1) ATE267015T1 (ja)
AU (1) AU704977B2 (ja)
BG (1) BG63122B1 (ja)
BR (1) BR9508886A (ja)
CA (1) CA2199117C (ja)
CZ (1) CZ297873B6 (ja)
DE (1) DE69533066T2 (ja)
DK (1) DK0781136T3 (ja)
ES (1) ES2219666T3 (ja)
FI (1) FI970918A (ja)
HU (1) HUT77172A (ja)
IL (1) IL115156A (ja)
IS (1) IS2011B (ja)
MY (1) MY121548A (ja)
NO (1) NO313268B1 (ja)
NZ (1) NZ335013A (ja)
OA (1) OA10473A (ja)
PL (2) PL188359B1 (ja)
PT (1) PT781136E (ja)
RO (1) RO118748B1 (ja)
RU (1) RU2168995C2 (ja)
SI (1) SI0781136T1 (ja)
SK (1) SK284564B6 (ja)
WO (1) WO1996007413A1 (ja)
ZA (1) ZA957483B (ja)

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CN1307421C (zh) 1997-08-08 2007-03-28 塞米得肿瘤学美国公司 克服生物及化学治疗抗性的方法与组合物
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US6653318B1 (en) 1999-07-21 2003-11-25 Yale University 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use
US6683061B1 (en) 1999-07-22 2004-01-27 Newbiotics, Inc. Enzyme catalyzed therapeutic activation
US6583149B1 (en) 1999-09-24 2003-06-24 Biochem Pharma Inc. Method for the treatment or prevention of viral infection using nucleoside analogues
US6566365B1 (en) 1999-11-04 2003-05-20 Biochem Pharma Inc. Method for the treatment of Flaviviridea viral infection using nucleoside analogues
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CA2441350A1 (en) 2001-01-19 2002-07-25 Newbiotics, Inc. Methods to treat autoimmune and inflammatory conditions
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MXPA04002365A (es) 2002-06-21 2004-11-22 Lg Electronics Inc Medio de grabacion que tiene estructura de datos para manejar la reproduccion de datos de video grabados en el mismo.
KR20040000290A (ko) 2002-06-24 2004-01-03 엘지전자 주식회사 고밀도 광디스크의 멀티 경로 데이터 스트림 관리방법
WO2004001751A1 (en) 2002-06-24 2003-12-31 Lg Electronics Inc. Recording medium having data structure including navigation control information for managing reproduction of video data recorded thereon and recording and reproducing methods and apparatuses
CA2459086C (en) 2002-06-28 2013-08-13 Lg Electronics Inc. Recording medium having data structure for managing recording and reproduction of multiple path data recorded thereon and recording and reproducing methods and apparatus
RU2347284C2 (ru) 2002-10-14 2009-02-20 Эл Джи Электроникс Инк. Носитель записи со структурой данных для управления воспроизведением записанного на нем множества аудиопотоков и способы и устройства записи и воспроизведения
CN100479051C (zh) 2002-10-15 2009-04-15 Lg电子有限公司 具有管理多路图形流重现的数据结构的记录介质及记录和重现方法和装置
US7720356B2 (en) 2002-11-12 2010-05-18 Lg Electronics Inc Recording medium having data structure for managing reproduction of multiple reproduction path video data recorded thereon and recording and reproducing methods and apparatuses
US7664372B2 (en) 2002-11-20 2010-02-16 Lg Electronics Inc. Recording medium having data structure for managing reproduction of multiple component data recorded thereon and recording and reproducing methods and apparatuses
US7693394B2 (en) 2003-02-26 2010-04-06 Lg Electronics Inc. Recording medium having data structure for managing reproduction of data streams recorded thereon and recording and reproducing methods and apparatuses
US7809775B2 (en) 2003-02-27 2010-10-05 Lg Electronics, Inc. Recording medium having data structure for managing playback control recorded thereon and recording and reproducing methods and apparatuses
EP1604356A4 (en) 2003-02-28 2009-12-16 Lg Electronics Inc RECORD MEDIUM WITH A DATA STRUCTURE FOR MANAGING THE RANDOM / SHUFFLE PLAYBACK OF RECORDED VIDEO DATA, AND METHOD AND DEVICES FOR RECORDING AND PLAYING
US7620301B2 (en) 2003-04-04 2009-11-17 Lg Electronics Inc. System and method for resuming playback
AU2004281525B2 (en) 2003-10-09 2010-01-28 Aresus Pharma GmbH The use of a polyphenol for the treatment of a cancerous or pre-cancerous lesion of the skin
CN103735560A (zh) 2005-06-07 2014-04-23 耶鲁大学 使用克来夫定和替比夫定治疗癌症和其它病症或疾病状态的方法
US7951788B2 (en) * 2005-12-02 2011-05-31 Yale University Method of treating cancer and other conditions or disease states using L-cytosine nucleoside analogs
NO324263B1 (no) 2005-12-08 2007-09-17 Clavis Pharma Asa Kjemiske forbindelser, anvendelse derav ved behandling av kreft, samt farmasoytiske preparater som omfatter slike forbindelser
CN101534835B (zh) * 2006-09-01 2012-05-30 佐治亚大学研究基金会 用于癌症的L-OddC的前药
CN102406649A (zh) * 2011-11-15 2012-04-11 张始状 人体五种正常碱基在制备治疗肿瘤药物中的应用
CN103720693A (zh) * 2011-11-15 2014-04-16 张始状 人体五种正常碱基在制备治疗肿瘤药物中的应用
SG10201609131YA (en) 2016-11-01 2018-06-28 Xylonix Ip Holdings Pte Ltd Zinc-pga compositions and methods for treating cancer
CN110168092A (zh) * 2016-12-28 2019-08-23 特朗斯吉有限公司 溶瘤病毒和治疗分子
SG10201708886RA (en) * 2017-10-30 2019-05-30 Xylonix Ip Holdings Pte Ltd α-PGA-ZINC COMPOSITIONS AND METHODS FOR TREATING CANCER

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Also Published As

Publication number Publication date
IL115156A (en) 2000-07-16
JP3979662B2 (ja) 2007-09-19
KR970705393A (ko) 1997-10-09
WO1996007413A1 (en) 1996-03-14
PL318971A1 (en) 1997-07-21
AP9700939A0 (en) 1997-04-30
ATE267015T1 (de) 2004-06-15
CA2199117A1 (en) 1996-03-14
SK284564B6 (sk) 2005-06-02
NO971015L (no) 1997-03-05
CZ297873B6 (cs) 2007-04-18
BG101284A (en) 1998-03-31
NO313268B1 (no) 2002-09-09
CN1448142A (zh) 2003-10-15
KR100374477B1 (ko) 2003-06-19
SK28197A3 (en) 1997-09-10
CN1111409C (zh) 2003-06-18
JPH10506385A (ja) 1998-06-23
DE69533066D1 (de) 2004-06-24
FI970918A0 (fi) 1997-03-04
AU704977B2 (en) 1999-05-13
US7262213B2 (en) 2007-08-28
CN1251680C (zh) 2006-04-19
EP0781136A1 (en) 1997-07-02
CN1160351A (zh) 1997-09-24
PL189288B1 (pl) 2005-07-29
DK0781136T3 (da) 2004-08-02
US6063787A (en) 2000-05-16
BR9508886A (pt) 1997-12-30
OA10473A (en) 2002-04-08
NZ335013A (en) 2000-07-28
US20050261320A1 (en) 2005-11-24
AP783A (en) 1999-11-17
AU3586295A (en) 1996-03-27
US8076347B2 (en) 2011-12-13
US20080171758A1 (en) 2008-07-17
IL115156A0 (en) 1995-12-31
ES2219666T3 (es) 2004-12-01
HUT77172A (hu) 1998-03-02
CZ63397A3 (en) 1997-07-16
PT781136E (pt) 2004-09-30
IS4434A (is) 1997-03-04
FI970918A (fi) 1997-05-02
NO971015D0 (no) 1997-03-05
DE69533066T2 (de) 2005-06-02
EP0781136B1 (en) 2004-05-19
MY121548A (en) 2006-02-28
RO118748B1 (ro) 2003-10-30
CN1827108A (zh) 2006-09-06
PL188359B1 (pl) 2005-01-31
RU2168995C2 (ru) 2001-06-20
IS2011B (is) 2005-05-13
EP1468687A1 (en) 2004-10-20
SI0781136T1 (en) 2004-08-31
BG63122B1 (en) 2001-04-30
CA2199117C (en) 2006-04-11
EP0781136A4 (en) 1999-06-23

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